ATE546653T1 - Pulsmedium-perfusionsbioreaktor mit verbessertem massentransport für mehrere 3-d-zellkonstrukte - Google Patents

Pulsmedium-perfusionsbioreaktor mit verbessertem massentransport für mehrere 3-d-zellkonstrukte

Info

Publication number
ATE546653T1
ATE546653T1 AT04801604T AT04801604T ATE546653T1 AT E546653 T1 ATE546653 T1 AT E546653T1 AT 04801604 T AT04801604 T AT 04801604T AT 04801604 T AT04801604 T AT 04801604T AT E546653 T1 ATE546653 T1 AT E546653T1
Authority
AT
Austria
Prior art keywords
bioreactor
cell constructs
mass transport
perfusion bioreactor
improved mass
Prior art date
Application number
AT04801604T
Other languages
English (en)
Inventor
Smadar Cohen
Tal Dvir
Michal Shachar
Original Assignee
Univ Ben Gurion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ben Gurion filed Critical Univ Ben Gurion
Application granted granted Critical
Publication of ATE546653T1 publication Critical patent/ATE546653T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04801604T 2003-12-09 2004-12-09 Pulsmedium-perfusionsbioreaktor mit verbessertem massentransport für mehrere 3-d-zellkonstrukte ATE546653T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52771603P 2003-12-09 2003-12-09
PCT/IL2004/001118 WO2005056747A2 (en) 2003-12-09 2004-12-09 Pulse-medium perfusion bioreactor with improved mass transport for multiple 3-d cell constructs

Publications (1)

Publication Number Publication Date
ATE546653T1 true ATE546653T1 (de) 2012-03-15

Family

ID=34676770

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04801604T ATE546653T1 (de) 2003-12-09 2004-12-09 Pulsmedium-perfusionsbioreaktor mit verbessertem massentransport für mehrere 3-d-zellkonstrukte

Country Status (5)

Country Link
US (1) US7608447B2 (de)
EP (1) EP1697494B1 (de)
AT (1) ATE546653T1 (de)
CA (1) CA2548464C (de)
WO (1) WO2005056747A2 (de)

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EP1693025A1 (de) * 2005-02-17 2006-08-23 Universität Zürich Verfahren zur Herstellung einer Prothese aus Gewebe
US20090061508A1 (en) * 2007-08-27 2009-03-05 Biomimetics Technologies Inc Laminar flow reactor
US9057044B2 (en) * 2006-08-30 2015-06-16 Meir Israelowitz Laminar flow reactor
WO2008109816A1 (en) * 2007-03-08 2008-09-12 Hemacell Perfusion, Inc. Method for isolation of afterbirth derived cells
US8278101B2 (en) * 2009-12-07 2012-10-02 Synthecon, Inc. Stem cell bioprocessing and cell expansion
RS59814B1 (sr) * 2009-12-16 2020-02-28 Vivabiocell Spa Skafold za rast tkiva in vivo
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
CN103194390B (zh) * 2013-04-19 2014-08-06 南方医科大学南方医院 双环路振荡灌注式生物反应系统
BR112015031253B1 (pt) 2013-06-13 2021-09-28 Orgenesis Ltd. Método para produção de uma população de células transdiferenciada
CN103614296B (zh) * 2013-11-15 2015-05-20 汪洋 一种双腔三维灌注生物反应器系统
JP6612227B2 (ja) 2013-11-16 2019-11-27 テルモ ビーシーティー、インコーポレーテッド バイオリアクターにおける細胞増殖
US11008547B2 (en) 2014-03-25 2021-05-18 Terumo Bct, Inc. Passive replacement of media
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
MA41296A (fr) 2014-12-30 2017-11-07 Orgenesis Ltd Procédés de transdifférenciation et procédés d'utilisation de ceux-ci
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN106010966B (zh) * 2016-06-08 2019-03-15 中山大学附属第一医院 多方向组织工程多孔材料灌注系统
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
WO2018207179A1 (en) 2017-05-08 2018-11-15 Orgenesis Ltd. Transdifferentiated cell populations and methods of use thereof
IT202000027290A1 (it) * 2020-11-13 2022-05-13 Gerardo Catapano Bioreattore, apparato e procedimento per la coltura in vitro di tessuti riproduttivi, e simili
GB2619893A (en) 2021-03-23 2023-12-20 Terumo Bct Inc Cell capture and expansion
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02109966A (ja) 1988-10-20 1990-04-23 Kirin Brewery Co Ltd ラジアルフロー式充填層型バイオリアクタ
US5068195A (en) 1988-11-02 1991-11-26 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion and maintenance vessel
EP0725134A3 (de) 1995-02-03 1998-05-13 NPBI Nederlands Produktielaboratorium voor Bloedtransfusieapparatuur en Infusievloeistoffen B.V. Flexibler Bioreaktor für therapeutische Zellen

Also Published As

Publication number Publication date
US7608447B2 (en) 2009-10-27
CA2548464C (en) 2013-02-12
EP1697494A2 (de) 2006-09-06
US20070111310A1 (en) 2007-05-17
EP1697494B1 (de) 2012-02-22
CA2548464A1 (en) 2005-06-23
WO2005056747A3 (en) 2005-08-04
WO2005056747A2 (en) 2005-06-23

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