ATE547176T1 - Mikrofluidische verfahren und systeme zur verwendung bei der analytdetektion - Google Patents
Mikrofluidische verfahren und systeme zur verwendung bei der analytdetektionInfo
- Publication number
- ATE547176T1 ATE547176T1 AT08789279T AT08789279T ATE547176T1 AT E547176 T1 ATE547176 T1 AT E547176T1 AT 08789279 T AT08789279 T AT 08789279T AT 08789279 T AT08789279 T AT 08789279T AT E547176 T1 ATE547176 T1 AT E547176T1
- Authority
- AT
- Austria
- Prior art keywords
- reagent
- reactor arrangement
- assembly
- systems
- holding means
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000012491 analyte Substances 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 6
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000006185 dispersion Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07112834A EP2017006A1 (de) | 2007-07-20 | 2007-07-20 | Mikrofluidische Verfahren und Systeme zur Verwendung bei der Analytdetektion |
| PCT/IB2008/052803 WO2009013658A2 (en) | 2007-07-20 | 2008-07-11 | Microfluidic methods and systems for use in detecting analytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE547176T1 true ATE547176T1 (de) | 2012-03-15 |
Family
ID=38695477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08789279T ATE547176T1 (de) | 2007-07-20 | 2008-07-11 | Mikrofluidische verfahren und systeme zur verwendung bei der analytdetektion |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100233824A1 (de) |
| EP (2) | EP2017006A1 (de) |
| JP (1) | JP2010534319A (de) |
| CN (1) | CN101754813A (de) |
| AT (1) | ATE547176T1 (de) |
| BR (1) | BRPI0813535A2 (de) |
| RU (1) | RU2010106175A (de) |
| WO (1) | WO2009013658A2 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2017618A1 (de) * | 2007-07-20 | 2009-01-21 | Koninklijke Philips Electronics N.V. | Detektionsverfahren und -systeme |
| US9086396B2 (en) | 2008-11-28 | 2015-07-21 | Roche Molecular Systems, Inc. | System and method for the automated processing of fluids, method for determining the matching of objects |
| WO2010098884A1 (en) | 2009-02-26 | 2010-09-02 | Jian-Ping Wang | High magnetic moment particle detection |
| DE102009040151B4 (de) * | 2009-05-26 | 2013-09-12 | Analytik Jena Ag | Anordnung zur Detektion von Chemolumineszenz an Gasen |
| DE102009048378B3 (de) * | 2009-10-06 | 2011-02-17 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Mikrofluidische Struktur |
| JP5506440B2 (ja) | 2010-02-08 | 2014-05-28 | 株式会社堀場製作所 | 液体試料定量器 |
| JP5892551B2 (ja) | 2010-06-30 | 2016-03-23 | 株式会社メタボスクリーン | マイクロ化学チップ、その製造方法、及びその使用方法 |
| KR101363157B1 (ko) * | 2010-10-07 | 2014-02-26 | 주식회사 세라젬메디시스 | 입체적 구조의 바이오센서 및 그 제조 방법 |
| DE102012205171B3 (de) * | 2012-03-29 | 2013-09-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Integriertes Einweg-Chipkartuschensystem für mobile Multiparameteranalysen chemischer und/oder biologischer Substanzen |
| DE102012109026A1 (de) * | 2012-09-25 | 2014-03-27 | Eads Deutschland Gmbh | Detektionsvorrichtung und Detektionsverfahren zur automatischen Bestimmung von Biomasse |
| CN102836751B (zh) * | 2012-09-28 | 2014-11-19 | 重庆大学 | 一种水凝胶微流控芯片及其加工方法 |
| EP2912432B1 (de) * | 2012-10-24 | 2018-07-04 | Genmark Diagnostics Inc. | Integrierte multiplex-zielanalyse |
| US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
| CN103846640B (zh) * | 2012-12-07 | 2017-02-15 | 哈尔滨工业大学深圳研究生院 | 微小孔的等离子体放电加工装置及加工方法 |
| CN105228748B (zh) | 2013-03-15 | 2017-10-10 | 金马克诊断股份有限公司 | 用于操纵可变形流体容器的系统、方法和设备 |
| US10155244B2 (en) * | 2013-09-16 | 2018-12-18 | Taiwan Semiconductor Manufacturing Co., Ltd. | Fluid deposition appartus and method |
| DE102013220908B4 (de) * | 2013-10-15 | 2015-09-24 | Continental Automotive Gmbh | Sensorelement |
| USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
| US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
| JP6632525B2 (ja) * | 2013-11-06 | 2020-01-22 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | マイクロ流体デバイスならびにその製造方法および使用方法 |
| EP2957912A1 (de) * | 2014-06-17 | 2015-12-23 | University College Dublin | Verfahren zur Markierung eines Zielmoleküls als Teil einer Korona von Molekülen auf der Oberfläche eines Objekts im Nanogrößenbereich |
| CN104166008B (zh) * | 2014-08-11 | 2016-03-02 | 江苏大学 | 一种微流控芯片自动同步进样方法与装置 |
| US10005080B2 (en) | 2014-11-11 | 2018-06-26 | Genmark Diagnostics, Inc. | Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation |
| EP3227671B1 (de) * | 2014-12-03 | 2021-02-24 | The Uwm Research Foundation, Inc. | Vorrichtung und verfahren zur erkennung von schadstoffen |
| CN104597242B (zh) * | 2015-02-06 | 2016-07-06 | 无锡市人民医院 | 一种实现肿瘤标志物富集的生物芯片及其应用 |
| US10369567B2 (en) * | 2015-11-04 | 2019-08-06 | International Business Machines Corporation | Continuous, capacitance-based monitoring of liquid flows in a microfluidic device |
| GB201611770D0 (en) * | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
| US11110457B2 (en) | 2017-12-28 | 2021-09-07 | Stmicroelectronics S.R.L. | Analysis unit for a transportable microfluidic device, in particular for sample preparation and molecule analysis |
| US11511278B2 (en) | 2017-12-28 | 2022-11-29 | Stmicroelectronics S.R.L. | Solid reagent containment unit, in particular for a portable microfluidic device for sample preparation and molecule analysis |
| US11278897B2 (en) | 2017-12-28 | 2022-03-22 | Stmicroelectronics S.R.L. | Cartridge for sample preparation and molecule analysis, cartridge control machine, sample preparation system and method using the cartridge |
| US11717825B2 (en) | 2017-12-28 | 2023-08-08 | Stmicroelectronics S.R.L. | Magnetically controllable valve and portable microfluidic device having a magnetically controllable valve, in particular cartridge for sample preparation and molecule analysis |
| US11491489B2 (en) | 2017-12-28 | 2022-11-08 | Stmicroelectronics S.R.L. | Microfluidic connector group, microfluidic device and manufacturing process thereof, in particular for a cartridge for sample preparation and molecule analysis |
| US20210231673A1 (en) * | 2018-08-17 | 2021-07-29 | President And Fellows Of Harvard College | Methods and compositions for detection and quantification of small molecules and other analytes |
| CN112169853B (zh) * | 2020-12-01 | 2021-02-26 | 南京岚煜生物科技有限公司 | 一种多功能微流控检测芯片 |
| CN113426497B (zh) * | 2021-06-02 | 2022-07-12 | 广州大学 | 一种微流控芯片的制造方法 |
| CN115814875B (zh) * | 2022-12-20 | 2025-08-29 | 融智生物科技(青岛)有限公司 | 微量点样系统 |
| CN119186432A (zh) * | 2024-09-23 | 2024-12-27 | 桂林电子科技大学 | 一种基于数字微流控的固液反应控制装置 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2424291C3 (de) | 1974-05-18 | 1978-09-21 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von anorganisches Pigment enthaltenden hydrophilen Polyolefinfasern |
| ATE272213T1 (de) * | 1999-06-18 | 2004-08-15 | Gamera Bioscience Corp | Vorrichtungen und verfahren zur durchführung miniaturisierter homogener tests |
| JP3442338B2 (ja) * | 2000-03-17 | 2003-09-02 | 株式会社日立製作所 | Dna分析装置、dna塩基配列決定装置、dna塩基配列決定方法、および反応モジュール |
| DE10111457B4 (de) * | 2001-03-09 | 2006-12-14 | Siemens Ag | Diagnoseeinrichtung |
| EP1412729A4 (de) * | 2001-06-20 | 2005-03-09 | Cytonome Inc | Mikrofluidisches system mit einem flüssigkeitsgrenzflächendurchlass als virtueller wand zur grenzflächenverbindung von flüssigkeiten mit dem mikrofluidischen system |
| JP2004317307A (ja) * | 2003-04-16 | 2004-11-11 | Arkray Inc | 試薬部対面分析用具およびこの分析用具の製造方法 |
| WO2004092725A1 (ja) * | 2003-04-16 | 2004-10-28 | Arkray Inc. | 試薬の拡散距離が短縮された分析用具およびその製造方法 |
| US20040265172A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method and apparatus for entry and storage of specimens into a microfluidic device |
| CN1934444A (zh) * | 2004-03-05 | 2007-03-21 | 艾格麦迪卡瑞士股份有限公司 | 用于确定生理液体中的分析物浓度的分析物测试系统 |
| FR2870247B1 (fr) | 2004-05-13 | 2006-09-08 | Centre Nat Rech Scient Cnrse | Composition de polymeres moulables a caractere hydrophile durable, canaux pour fluides aqueux a base de cette composition, systeme microfluidique incorporant ces canaux et son procede de fabrication |
| CN1957257A (zh) | 2004-05-24 | 2007-05-02 | 皇家飞利浦电子股份有限公司 | 用于高灵敏度深度探测的磁阻传感器 |
| KR100635110B1 (ko) * | 2004-12-09 | 2006-10-17 | 주식회사 바이오디지트 | 현장분석용 랩온어칩 및 랩온어칩용 신호탐지기 |
| JP2008532929A (ja) | 2005-02-01 | 2008-08-21 | メディバス エルエルシー | ワクチン送達組成物および使用法 |
| EP1920246B1 (de) * | 2005-08-31 | 2010-03-10 | Egomedical Technologies AG | Gerinnungstestsystem |
-
2007
- 2007-07-20 EP EP07112834A patent/EP2017006A1/de not_active Ceased
-
2008
- 2008-07-11 CN CN200880025402.XA patent/CN101754813A/zh active Pending
- 2008-07-11 WO PCT/IB2008/052803 patent/WO2009013658A2/en not_active Ceased
- 2008-07-11 RU RU2010106175/05A patent/RU2010106175A/ru not_active Application Discontinuation
- 2008-07-11 EP EP08789279A patent/EP2170515B1/de not_active Not-in-force
- 2008-07-11 AT AT08789279T patent/ATE547176T1/de active
- 2008-07-11 BR BRPI0813535-5A2A patent/BRPI0813535A2/pt not_active IP Right Cessation
- 2008-07-11 US US12/669,213 patent/US20100233824A1/en not_active Abandoned
- 2008-07-11 JP JP2010516624A patent/JP2010534319A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2017006A1 (de) | 2009-01-21 |
| CN101754813A (zh) | 2010-06-23 |
| WO2009013658A3 (en) | 2009-03-12 |
| WO2009013658A2 (en) | 2009-01-29 |
| US20100233824A1 (en) | 2010-09-16 |
| EP2170515A2 (de) | 2010-04-07 |
| BRPI0813535A2 (pt) | 2014-12-30 |
| JP2010534319A (ja) | 2010-11-04 |
| EP2170515B1 (de) | 2012-02-29 |
| RU2010106175A (ru) | 2011-08-27 |
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