ATE547701T1 - Assays auf membranbasis - Google Patents

Assays auf membranbasis

Info

Publication number
ATE547701T1
ATE547701T1 AT03795701T AT03795701T ATE547701T1 AT E547701 T1 ATE547701 T1 AT E547701T1 AT 03795701 T AT03795701 T AT 03795701T AT 03795701 T AT03795701 T AT 03795701T AT E547701 T1 ATE547701 T1 AT E547701T1
Authority
AT
Austria
Prior art keywords
membrane
bilayers
bilayer
fluid
based assays
Prior art date
Application number
AT03795701T
Other languages
English (en)
Inventor
Vikky Yamazaki
Robert Schafer
Morrison Ulman
John Groves
Original Assignee
Synamem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synamem Corp filed Critical Synamem Corp
Application granted granted Critical
Publication of ATE547701T1 publication Critical patent/ATE547701T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT03795701T 2002-09-11 2003-09-11 Assays auf membranbasis ATE547701T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41017302P 2002-09-11 2002-09-11
PCT/US2003/028762 WO2004025262A2 (en) 2002-09-11 2003-09-11 Membrane-based assays

Publications (1)

Publication Number Publication Date
ATE547701T1 true ATE547701T1 (de) 2012-03-15

Family

ID=31994083

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03795701T ATE547701T1 (de) 2002-09-11 2003-09-11 Assays auf membranbasis

Country Status (7)

Country Link
US (3) US7407768B2 (de)
EP (1) EP1546696B1 (de)
JP (1) JP2005538377A (de)
AT (1) ATE547701T1 (de)
AU (1) AU2003266155A1 (de)
CA (1) CA2497139A1 (de)
WO (1) WO2004025262A2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004025262A2 (en) * 2002-09-11 2004-03-25 Synamem Corporation Membrane-based assays
WO2005084369A2 (en) * 2004-03-03 2005-09-15 The Regents Of The University Of California Arrays of colloidal crystals
US20080304068A1 (en) * 2004-04-28 2008-12-11 Tsuneo Urisu Biochip Production Method, Biochip, Biochip Analysis Apparatus, and Biochip Analysis Method
SE0403139D0 (sv) * 2004-12-23 2004-12-23 Nanoxis Ab Device and use thereof
JP2005283567A (ja) * 2005-02-15 2005-10-13 Kenji Sato プロテインチップ
WO2007084962A2 (en) * 2006-01-18 2007-07-26 The Regents Of The University Of California A fluid membrane-based ligand display system for live cell assays and disease diagnosis applications
JP4822903B2 (ja) * 2006-03-30 2011-11-24 株式会社東芝 二分子膜の形成装置及びその形成方法
JP2008020412A (ja) * 2006-07-14 2008-01-31 Sony Corp バイオアッセイ用基板、及び、バイオアッセイ方法
JP2008249433A (ja) * 2007-03-29 2008-10-16 Kansai Bunri Sogo Gakuen 被験物質に対するプローブの結合親和性を測定する方法及びその利用
ES2307430B1 (es) * 2007-05-09 2009-10-20 Consejo Superior De Investigaciones Cientificas Biosensor y sus aplicaciones.
US7829272B2 (en) 2007-05-24 2010-11-09 Nanotrope Inc. Viral detection liposomes and method
US8492315B2 (en) * 2007-08-28 2013-07-23 Life Bioscience, Inc. Method of providing a pattern of biological-binding areas for biological testing
US20090131263A1 (en) * 2007-11-19 2009-05-21 Longying Dong Normalization methods for G-protein coupled receptor membrane array
WO2010123608A2 (en) 2009-01-29 2010-10-28 The Regents Of The University Of California A spatial biomarker of disease and detection of spatial organization of cellular recptors
JP5230300B2 (ja) * 2008-08-26 2013-07-10 日本電信電話株式会社 生体分子機能解析用基板、生体分子機能解析用試料体および生体分子機能解析方法
WO2010080640A2 (en) 2008-12-18 2010-07-15 The Texas A&M University System A ph modulation method to detect ligand-receptor binding
WO2010085259A1 (en) * 2009-01-26 2010-07-29 Nanotrope, Inc. Viral detection liposomes and method
US9678055B2 (en) 2010-02-08 2017-06-13 Genia Technologies, Inc. Methods for forming a nanopore in a lipid bilayer
WO2011097028A1 (en) * 2010-02-08 2011-08-11 Genia Technologies, Inc. Systems and methods for manipulating a molecule in a nanopore
US9605307B2 (en) 2010-02-08 2017-03-28 Genia Technologies, Inc. Systems and methods for forming a nanopore in a lipid bilayer
US20120052188A1 (en) 2010-02-08 2012-03-01 Genia Technologies, Inc. Systems and methods for assembling a lipid bilayer on a substantially planar solid surface
WO2012075313A2 (en) 2010-12-01 2012-06-07 The Texas A&M University System Ph modulation methods and systems for detecting binding events
US8962242B2 (en) 2011-01-24 2015-02-24 Genia Technologies, Inc. System for detecting electrical properties of a molecular complex
US8399262B2 (en) 2011-03-23 2013-03-19 Darrel A. Mazzari Biosensor
US8753309B2 (en) 2011-06-24 2014-06-17 The Invention Science Fund I, Llc Device, system, and method including micro-patterned cell treatment array
US8986629B2 (en) 2012-02-27 2015-03-24 Genia Technologies, Inc. Sensor circuit for controlling, detecting, and measuring a molecular complex
US9759711B2 (en) 2013-02-05 2017-09-12 Genia Technologies, Inc. Nanopore arrays
US9869675B2 (en) * 2013-03-13 2018-01-16 Vanderbilt University Low resource processor using surface tension valves for extracting, concentrating, and detecting whole cells
US9551697B2 (en) 2013-10-17 2017-01-24 Genia Technologies, Inc. Non-faradaic, capacitively coupled measurement in a nanopore cell array
KR101568565B1 (ko) * 2014-01-06 2015-11-23 서울대학교산학협력단 이동성이 조절된 탐침이 결합된 지지형 지질 이중층을 포함하는 인공세포막 및 이를 이용하여 분자 간 상호작용을 분석하는 방법
KR101940981B1 (ko) 2014-05-05 2019-01-23 3디 글래스 솔루션즈 인코포레이티드 2d 및 3d 인덕터 안테나 및 변압기 제작 광 활성 기판
JP6404785B2 (ja) * 2015-08-12 2018-10-17 日本電信電話株式会社 生体分子移動度制御方法および電気泳動槽
US10070533B2 (en) 2015-09-30 2018-09-04 3D Glass Solutions, Inc. Photo-definable glass with integrated electronics and ground plane
KR20200010598A (ko) 2016-02-25 2020-01-30 3디 글래스 솔루션즈 인코포레이티드 3d 커패시터 및 커패시터 어레이 제작용 광활성 기재
US12165809B2 (en) 2016-02-25 2024-12-10 3D Glass Solutions, Inc. 3D capacitor and capacitor array fabricating photoactive substrates
WO2017177171A1 (en) 2016-04-08 2017-10-12 3D Glass Solutions, Inc. Methods of fabricating photosensitive substrates suitable for optical coupler
WO2018200804A1 (en) 2017-04-28 2018-11-01 3D Glass Solutions, Inc. Rf circulator
AU2018297035B2 (en) 2017-07-07 2021-02-25 3D Glass Solutions, Inc. 2D and 3D RF lumped element devices for RF system in a package photoactive glass substrates
WO2019118761A1 (en) 2017-12-15 2019-06-20 3D Glass Solutions, Inc. Coupled transmission line resonate rf filter
US11577248B2 (en) * 2017-12-21 2023-02-14 Mcmaster University Biological membrane-based sensor
KR102600200B1 (ko) 2018-01-04 2023-11-10 3디 글래스 솔루션즈 인코포레이티드 고효율 ｒｆ 회로들을 위한 임피던스 정합 도전성 구조
KR102145746B1 (ko) 2018-04-10 2020-08-19 3디 글래스 솔루션즈 인코포레이티드 Rf 집적형 전력 조절 커패시터
KR102475010B1 (ko) 2018-05-29 2022-12-07 3디 글래스 솔루션즈 인코포레이티드 저 삽입 손실 rf 전송 라인
KR102518025B1 (ko) 2018-09-17 2023-04-06 3디 글래스 솔루션즈 인코포레이티드 접지면을 갖는 고효율 컴팩트형 슬롯 안테나
JP7241433B2 (ja) 2018-12-28 2023-03-17 スリーディー グラス ソリューションズ，インク 光活性ガラス基板におけるｒｆ、マイクロ波及びｍｍ波システムのためのヘテロジニアスインテグレーション
WO2020139955A1 (en) 2018-12-28 2020-07-02 3D Glass Solutions, Inc. Annular capacitor rf, microwave and mm wave systems
WO2020206323A1 (en) 2019-04-05 2020-10-08 3D Glass Solutions, Inc. Glass based empty substrate integrated waveguide devices
WO2020214788A1 (en) 2019-04-18 2020-10-22 3D Glass Solutions, Inc. High efficiency die dicing and release
WO2021211855A1 (en) 2020-04-17 2021-10-21 3D Glass Solutions, Inc. Broadband inductor
WO2021215803A1 (ko) * 2020-04-21 2021-10-28 서울대학교산학협력단 지질 나노필러 어레이 기반 면역 측정법
US11740180B2 (en) * 2020-09-28 2023-08-29 Purdue Research Foundation Method of measuring diffusion in a medium
CN113654953A (zh) * 2021-07-29 2021-11-16 山东大学深圳研究院 一种检测纳米颗粒污染物环境行为和生物效应的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US579030A (en) * 1897-03-16 Basket
IL93020A (en) * 1990-01-09 1995-06-29 Yeda Res & Dev Biosensors comprising a lipid bilayer doped with ion channels anchored to a recording electrode by bridging molecules
JPH10502333A (ja) * 1994-04-07 1998-03-03 プロティーンニックス カンパニー バソアクティブ・インテスティナル・ポリペプチド
US5798030A (en) * 1995-05-17 1998-08-25 Australian Membrane And Biotechnology Research Institute Biosensor membranes
DE19607279A1 (de) * 1996-02-27 1997-08-28 Bayer Ag Durch Festkörper unterstützte Membran-Biosensoren
FI102922B (fi) * 1996-06-28 1999-03-15 Valtion Teknillinen Fluoresenssiin perustuva immunomääritysmenetelmä
US7384923B2 (en) * 1999-05-14 2008-06-10 Lipoxen Technologies Limited Liposomes
US6228326B1 (en) * 1996-11-29 2001-05-08 The Board Of Trustees Of The Leland Stanford Junior University Arrays of independently-addressable supported fluid bilayer membranes
US6699719B2 (en) * 1996-11-29 2004-03-02 Proteomic Systems, Inc. Biosensor arrays and methods
US5977311A (en) * 1997-09-23 1999-11-02 Curagen Corporation 53BP2 complexes
WO1999067640A1 (en) * 1998-06-22 1999-12-29 The Regents Of The University Of California Triggered optical biosensor
US6616946B1 (en) * 1999-11-15 2003-09-09 Biocure, Inc. Triblock copolymer hollow particles for agent delivery by permeability change
EP1238076A2 (de) * 1999-11-24 2002-09-11 PHARMACIA & UPJOHN COMPANY G protein-gekoppelter rezeptor-ähnliche rezeptoren und modulatoren davon
US6977155B2 (en) * 2000-08-10 2005-12-20 Corning Incorporated Arrays of biological membranes and methods and use thereof
WO2004025262A2 (en) * 2002-09-11 2004-03-25 Synamem Corporation Membrane-based assays

Also Published As

Publication number Publication date
US20080248492A1 (en) 2008-10-09
AU2003266155A1 (en) 2004-04-30
US7407768B2 (en) 2008-08-05
EP1546696A4 (de) 2009-07-29
EP1546696B1 (de) 2012-02-29
EP1546696A2 (de) 2005-06-29
WO2004025262A3 (en) 2004-06-17
AU2003266155A8 (en) 2004-04-30
WO2004025262A2 (en) 2004-03-25
JP2005538377A (ja) 2005-12-15
CA2497139A1 (en) 2004-03-25
US20080176759A1 (en) 2008-07-24
US20040053337A1 (en) 2004-03-18

Similar Documents

Publication Publication Date Title
ATE547701T1 (de) Assays auf membranbasis
EP2176659B1 (de) Mikrofluidische sensorkomplex-struktur
ATE322010T1 (de) Anordnungen von unabhängig voneinander ansteuerbaren, gestützten flüssigbilayer- membranen und ihre anwendungsverfahren
WO2009097174A3 (en) Electrochemical biosensor
WO2006116111A3 (en) Interdigitated chemical sensors, and methods of making and using the same
WO2004044120A3 (en) Multiwell insert device that enables label free detection of cells and other objects
NZ577992A (en) Assay membrane and method of use thereof
WO2008067386A3 (en) Piezoelectric microcantilever sensors for biosensing
GB2438124B (en) Dual path immunoassay device
DK1697752T3 (da) Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner
JP2007526452A5 (de)
EP2047259A4 (de) Biosensor mit interdigitalen elektrodensensoreinheiten
IL285831B (en) Low sample volume sensing device
WO2006107506A3 (en) System and method for performing g protein coupled receptor (gpcr) cell assays using waveguide-grating sensors
US12560572B2 (en) Transistor-based biological assay system comprising mating receptacle plate and gate electrode plate
Yang et al. Electrical percolation-based biosensor for real-time direct detection of staphylococcal enterotoxin B (SEB)
DK1579210T3 (da) Kolorimetriske sensorer, som er konstrueret af diacetylenmaterialer
TW200619616A (en) Sensor for detecting substance in liquid and device for detecting substance in liquid employing the sensor
Park et al. A calcium ion-selective electrode array for monitoring the activity of HepG2/C3As in a microchannel
ATE454418T1 (de) Chemische sensoren, die anilinpolysiloxane als empfindliche substanzen enthalten, und ihre verwendung zum nachweis und zur quantitativen analyse von nitroverbindungen
EP1790982A4 (de) Test der männlichen Fertilität
Porter et al. Detection of Crude Oil in Subsea Environments Using Organic Electrochemical Transistors
RU2007133641A (ru) Сенсорный чип и сенсорная система
WO2007001410A3 (en) Integrated sensing array for producing a biofingerprint of an analyte
ATE421687T1 (de) Biochemischer sensor mit thermoelastischen sonden