ATE548059T1 - Bioartifizieller nierentubulus - Google Patents
Bioartifizieller nierentubulusInfo
- Publication number
- ATE548059T1 ATE548059T1 AT07829816T AT07829816T ATE548059T1 AT E548059 T1 ATE548059 T1 AT E548059T1 AT 07829816 T AT07829816 T AT 07829816T AT 07829816 T AT07829816 T AT 07829816T AT E548059 T1 ATE548059 T1 AT E548059T1
- Authority
- AT
- Austria
- Prior art keywords
- bioartificial
- renal
- mek inhibitor
- artificial membrane
- cells
- Prior art date
Links
- 229940124647 MEK inhibitor Drugs 0.000 abstract 3
- 239000000823 artificial membrane Substances 0.000 abstract 3
- 239000002829 mitogen activated protein kinase inhibitor Substances 0.000 abstract 3
- 210000005239 tubule Anatomy 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000003734 kidney Anatomy 0.000 abstract 2
- 210000004926 tubular epithelial cell Anatomy 0.000 abstract 2
- 230000030944 contact inhibition Effects 0.000 abstract 1
- 238000009563 continuous hemofiltration Methods 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 239000002356 single layer Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
- A61M1/3489—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents by biological cells, e.g. bioreactor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/10—Hollow fibers or tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/16—Hollow fibers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Immunology (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006282826 | 2006-10-17 | ||
| PCT/JP2007/070082 WO2008047760A1 (fr) | 2006-10-17 | 2007-10-15 | Tubule rénal bioartificiel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548059T1 true ATE548059T1 (de) | 2012-03-15 |
Family
ID=39313987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07829816T ATE548059T1 (de) | 2006-10-17 | 2007-10-15 | Bioartifizieller nierentubulus |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090209019A1 (de) |
| EP (1) | EP2075019B1 (de) |
| JP (1) | JP5166275B2 (de) |
| AT (1) | ATE548059T1 (de) |
| WO (1) | WO2008047760A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5671791B2 (ja) * | 2009-09-04 | 2015-02-18 | ニプロ株式会社 | 近位尿細管上皮細胞(rptec)の培養方法 |
| EP2482867A1 (de) * | 2009-10-02 | 2012-08-08 | Agency For Science, Technology And Research | Verbesserte bioartifizielle nieren |
| SG190002A1 (en) | 2010-10-25 | 2013-06-28 | Agency Science Tech & Res | Tubular fiber membrane with nanoporous skin |
| US9447407B2 (en) | 2011-02-02 | 2016-09-20 | Agency For Science, Technology And Research | Double coating procedure for the membranes of bioartificial kidneys |
| JP2012157653A (ja) * | 2011-02-02 | 2012-08-23 | Agency For Science Technology & Research | バイオ人工腎臓の膜のための二重コーティング手法 |
| US20120301958A1 (en) | 2011-05-27 | 2012-11-29 | Advanced Technologies And Regenerative Medicine, Llc | Bioartificial proximal tubule systems and methods of use |
| JP6755085B2 (ja) * | 2015-11-10 | 2020-09-16 | 日機装株式会社 | 細胞支持複合体および細胞支持複合体の製造方法 |
| JP6605618B2 (ja) | 2015-11-10 | 2019-11-20 | 日機装株式会社 | 細胞支持複合体および細胞支持複合体の製造方法 |
| JP6995112B2 (ja) | 2017-04-06 | 2022-02-04 | 日機装株式会社 | 細胞の培養方法及び細胞支持複合体の製造方法 |
| JP6876327B2 (ja) * | 2017-04-28 | 2021-05-26 | 国立大学法人静岡大学 | 血液浄化装置 |
| US20190247560A1 (en) * | 2018-02-13 | 2019-08-15 | Gambro Lundia Ab | Extracorporeal devices and methods of treating complement factor related diseases |
| JP6978585B2 (ja) | 2018-03-22 | 2021-12-08 | 日機装株式会社 | 細胞の培養方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3426331A1 (de) | 1984-07-17 | 1986-01-30 | 6380 Bad Homburg Fresenius AG | Asymmetrische mikroporoese hohlfaser fuer die haemodialyse sowie verfahren zu ihrer herstellung |
| WO1989001967A1 (en) * | 1987-09-03 | 1989-03-09 | Brown University Research Foundation | Blood purification with cultured renal cells |
| US5549674A (en) * | 1992-03-02 | 1996-08-27 | The Regents Of The University Of Michigan | Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo |
| AU4331897A (en) * | 1996-09-05 | 1998-03-26 | Children's Medical Center Corporation | Prosthetic kidney and its use for treating kidney disease |
| US6150164A (en) * | 1996-09-30 | 2000-11-21 | The Regents Of The University Of Michigan | Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo |
| JP2000271213A (ja) * | 1999-03-26 | 2000-10-03 | Daikin Ind Ltd | 定濃度酸素供給装置 |
| WO2002091955A1 (en) * | 2001-05-17 | 2002-11-21 | Kaneka Corporation | Artificial kidney having function of metabolizing protein and mehtod of constructing the same |
| JP2003055266A (ja) * | 2001-06-04 | 2003-02-26 | Univ Texas Syst | Mek5ならびに心臓肥大および拡張型心筋症に関連する方法および組成物 |
| ATE486540T1 (de) * | 2003-12-23 | 2010-11-15 | Fmc Biopolymer As | Verwendung von alginat-matrizen zur kontrolle des zellwachstums |
-
2007
- 2007-10-15 WO PCT/JP2007/070082 patent/WO2008047760A1/ja not_active Ceased
- 2007-10-15 US US12/441,106 patent/US20090209019A1/en not_active Abandoned
- 2007-10-15 JP JP2008539804A patent/JP5166275B2/ja active Active
- 2007-10-15 AT AT07829816T patent/ATE548059T1/de active
- 2007-10-15 EP EP07829816A patent/EP2075019B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008047760A1 (fr) | 2008-04-24 |
| JPWO2008047760A1 (ja) | 2010-02-25 |
| JP5166275B2 (ja) | 2013-03-21 |
| EP2075019B1 (de) | 2012-03-07 |
| US20090209019A1 (en) | 2009-08-20 |
| EP2075019A1 (de) | 2009-07-01 |
| EP2075019A4 (de) | 2011-02-23 |
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