ATE549351T1 - Chimärer peptidantagonist für gpcr135 oder gpcr142 - Google Patents

Chimärer peptidantagonist für gpcr135 oder gpcr142

Info

Publication number
ATE549351T1
ATE549351T1 AT08724770T AT08724770T ATE549351T1 AT E549351 T1 ATE549351 T1 AT E549351T1 AT 08724770 T AT08724770 T AT 08724770T AT 08724770 T AT08724770 T AT 08724770T AT E549351 T1 ATE549351 T1 AT E549351T1
Authority
AT
Austria
Prior art keywords
gpcr135
gpcr142
chimeric peptide
peptide antagonist
gpcr1
Prior art date
Application number
AT08724770T
Other languages
English (en)
Inventor
Chester Kuei
Changlu Liu
Cindy Pudiak
Jonathan Shelton
Steven Sutton
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE549351T1 publication Critical patent/ATE549351T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT08724770T 2007-01-30 2008-01-23 Chimärer peptidantagonist für gpcr135 oder gpcr142 ATE549351T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89869307P 2007-01-30 2007-01-30
PCT/US2008/000917 WO2008094437A2 (en) 2007-01-30 2008-01-23 Chimeric peptide antagonist for gpcr135 or gpcr142

Publications (1)

Publication Number Publication Date
ATE549351T1 true ATE549351T1 (de) 2012-03-15

Family

ID=39674681

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08724770T ATE549351T1 (de) 2007-01-30 2008-01-23 Chimärer peptidantagonist für gpcr135 oder gpcr142

Country Status (4)

Country Link
US (1) US8299028B2 (de)
EP (1) EP2129359B1 (de)
AT (1) ATE549351T1 (de)
WO (1) WO2008094437A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008318278B2 (en) * 2007-10-30 2014-05-29 Howard Florey Institute Chimeric relaxin polypeptides comprising an A and B chain derived from different relaxin family peptides
AU2011301146B2 (en) * 2010-09-08 2016-01-21 Howard Florey Institute Of Experimental Physiology And Medicine Single chain relaxin polypeptides
WO2012031328A1 (en) * 2010-09-08 2012-03-15 Howard Florey Institute Of Experimental Physiology And Medicine Treatments for substance abuse and addiction

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2402614A1 (en) * 2000-03-10 2001-09-20 Zymogenetics, Inc. Insulin homolog polypeptide zins4
CA2406855A1 (en) * 2000-04-21 2001-11-01 Takeda Chemical Industries, Ltd. Novel insulin/igf/relaxin family polypeptides and dnas thereof
AU2001276837A1 (en) 2000-06-23 2002-01-08 Tularik, Inc. Human and mouse g-protein couipled receptors
AUPR814401A0 (en) * 2001-10-08 2001-11-01 Howard Florey Institute Of Experimental Physiology And Medicine Human 3 relaxin
EP1599168A2 (de) 2003-03-04 2005-11-30 Janssen Pharmaceutica N.V. Relaxin3-gpcr135-komplexe und ihre herstellung und verwendung
AU2003903124A0 (en) 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
CA2530048A1 (en) 2003-06-30 2005-01-20 Merck & Co., Inc. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
WO2005014616A2 (en) 2003-08-07 2005-02-17 Janssen Pharmaceutica N.V. Complexes of gpcr142 and relaxin3 or insl5, and their production and use
ATE555126T1 (de) 2004-08-25 2012-05-15 Janssen Pharmaceutica Nv Relaxin-chimere polypeptide und deren herstellung und anwendung
ATE479678T1 (de) 2006-03-31 2010-09-15 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyridine als modulatoren des histamin-h4-rezeptors

Also Published As

Publication number Publication date
WO2008094437A2 (en) 2008-08-07
WO2008094437A3 (en) 2008-11-06
EP2129359A2 (de) 2009-12-09
US8299028B2 (en) 2012-10-30
EP2129359B1 (de) 2012-03-14
EP2129359A4 (de) 2011-05-18
US20100145007A1 (en) 2010-06-10

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