ATE550073T1 - Protein c für die wundheilung - Google Patents
Protein c für die wundheilungInfo
- Publication number
- ATE550073T1 ATE550073T1 AT02729651T AT02729651T ATE550073T1 AT E550073 T1 ATE550073 T1 AT E550073T1 AT 02729651 T AT02729651 T AT 02729651T AT 02729651 T AT02729651 T AT 02729651T AT E550073 T1 ATE550073 T1 AT E550073T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- apc
- wound healing
- agent
- medicament
- Prior art date
Links
- 230000029663 wound healing Effects 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 101800004937 Protein C Proteins 0.000 abstract 2
- 102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 abstract 2
- 101800001700 Saposin-D Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229960000856 protein c Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR5637A AUPR563701A0 (en) | 2001-06-13 | 2001-06-13 | Treatment and composition for wound healing |
| AUPS1433A AUPS143302A0 (en) | 2002-04-02 | 2002-04-02 | Treatment and composition for wound healing |
| PCT/AU2002/000751 WO2002100445A1 (en) | 2001-06-13 | 2002-06-11 | Treatment and composition for wound healing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE550073T1 true ATE550073T1 (de) | 2012-04-15 |
Family
ID=25646727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02729651T ATE550073T1 (de) | 2001-06-13 | 2002-06-11 | Protein c für die wundheilung |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20040176288A1 (de) |
| EP (1) | EP1404412B1 (de) |
| JP (1) | JP4351041B2 (de) |
| AT (1) | ATE550073T1 (de) |
| AU (1) | AU2002302192B2 (de) |
| CA (1) | CA2450240A1 (de) |
| ES (1) | ES2384099T3 (de) |
| WO (1) | WO2002100445A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4516844B2 (ja) | 2002-09-16 | 2010-08-04 | エイジェニックス インコーポレイテッド | 創傷の処置におけるラクトフェリン |
| US7183381B2 (en) | 2004-10-26 | 2007-02-27 | Agennix, Inc. | Composition of lactoferrin related peptides and uses thereof |
| US20080293631A1 (en) * | 2005-01-07 | 2008-11-27 | Christopher John Jackson | Treatment for Autoimmune and Inflammatory Conditions |
| SG158919A1 (en) | 2005-01-24 | 2010-02-26 | Univ Texas | Constructs binding to phosphatidylserine and their use in disease treatment |
| BRPI0613227A2 (pt) * | 2005-06-09 | 2011-01-04 | Chiang Chuan Chi | uma composição para cicatrização de ferida e uso desta |
| EP1971365A4 (de) * | 2005-12-20 | 2010-01-13 | Swiss American Products Inc | Proteasezusammensetzungen zur behandlung von geschädigtem gewebe |
| GR1005700B (el) * | 2006-09-01 | 2007-10-22 | (40%) ����� �������� | Τροπος αντιμετωπισης της 1ης φασης του εγκαυματοσσε μη σηπτικους ασθενεις με συνεχη ενδοφλεβια χορηγηση ενεργοποιημενης πρωτεινης-c για 48 ωρες με στοχο τη μειωση της τελικης εγκαυματικης βλαβης καιαυξηση της ταχυτητας επουλωσης κατα τα πρωτα επτα μετεγκαυματικα 24ωρα |
| EP2014296A1 (de) * | 2007-07-10 | 2009-01-14 | PAION Deutschland GmbH | Neuartige Strategien zur Erhöhung der Reperfusion in einem verstopften Blutgefäß |
| AR067345A1 (es) * | 2007-07-10 | 2009-10-07 | Paion Deutschland Gmbh | Uso de trombomodulina para la preparacion de un medicamento trombolitico |
| GB2457965B8 (en) * | 2008-07-01 | 2011-02-16 | Renovo Ltd | Methods and systems for determining efficacy of medicaments. |
| EP2852401A4 (de) * | 2012-04-02 | 2015-11-11 | Univ Saint Louis | Verfahren und zusammensetzungen zur reduzierung des auftretens von postchirurgischer verklebung |
| IN2014DN11181A (de) * | 2012-07-04 | 2015-10-02 | Univ Sydney | |
| PL3137102T3 (pl) * | 2014-04-16 | 2022-02-07 | Zz Biotech Llc | Apc do stosowania w leczeniu nieprawidłowego bliznowacenia skóry |
| US20170035862A1 (en) | 2014-04-16 | 2017-02-09 | Zz Biotech Llc | Use of APC analogue for wound healing |
| TR202021285A1 (tr) * | 2020-12-22 | 2022-07-21 | Univ Yeditepe | Yara skarinin önlenmesi̇ ve tedavi̇si̇nde kullanilmak üzere erbium borat i̇çeren formülasyon |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571786A (en) * | 1990-08-16 | 1996-11-05 | Immuno Aktiengesellschaft | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
| US6197325B1 (en) * | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| US5648380A (en) * | 1991-03-01 | 1997-07-15 | Warner-Lambert Company | Anti-inflammatory wound healing compositions and methods for preparing and using same |
| AT397615B (de) | 1991-05-14 | 1994-05-25 | Immuno Ag | Arzneimittel enthaltend protein c |
| US5279956A (en) * | 1991-06-24 | 1994-01-18 | The Scripps Research Institute | Activated protein C polypeptides and anti-peptide antibodies, diagnostic methods and systems for inhibiting activated protein C |
| WO1994002172A1 (en) * | 1992-07-24 | 1994-02-03 | Oklahoma Medical Research Foundation | Blockade of protein c activation reduces microvascular surgical blood loss |
| US5583102A (en) * | 1993-12-03 | 1996-12-10 | University Of Iowa Research Foundation | Human thrombomodulin in wound healing |
| WO1995030429A1 (en) * | 1994-05-04 | 1995-11-16 | Board Of Trustees Of The University Of Arkansas | Novel ophthalmologic uses of protein c |
| JP3802104B2 (ja) | 1995-05-31 | 2006-07-26 | 財団法人化学及血清療法研究所 | 脊髄損傷に伴う神経障害の予防・治療剤 |
| SE9600216D0 (sv) * | 1996-01-18 | 1996-01-18 | Hans Arne Hansson | Styrning av läkningsprocesser |
| HUP0001237A3 (en) * | 1997-10-20 | 2002-01-28 | Lilly Co Eli | Methods for treating vascular disorders |
| JP3578627B2 (ja) * | 1998-05-15 | 2004-10-20 | 株式会社ホギメディカル | 創傷患部の治癒を促進する組織シーラント |
| CA2358492A1 (en) | 1998-12-21 | 2000-06-29 | Eli Lilly And Company | Combination therapy for the treatment of sepsis |
| CA2398929C (en) | 2000-02-04 | 2011-05-31 | The Scripps Research Institute | Neuroprotective, antithrombotic and anti-flammatory uses of activated protein c (apc) |
| US7204981B2 (en) * | 2000-03-28 | 2007-04-17 | Eli Lilly And Company | Methods of treating diseases with activated protein C |
| AU2001245319A1 (en) * | 2000-03-28 | 2001-10-08 | Eli Lilly And Company | Methods of treating diseases with activated protein c |
-
2002
- 2002-06-11 AT AT02729651T patent/ATE550073T1/de active
- 2002-06-11 ES ES02729651T patent/ES2384099T3/es not_active Expired - Lifetime
- 2002-06-11 CA CA002450240A patent/CA2450240A1/en not_active Abandoned
- 2002-06-11 AU AU2002302192A patent/AU2002302192B2/en not_active Expired
- 2002-06-11 EP EP02729651A patent/EP1404412B1/de not_active Expired - Lifetime
- 2002-06-11 JP JP2003503264A patent/JP4351041B2/ja not_active Expired - Lifetime
- 2002-06-11 WO PCT/AU2002/000751 patent/WO2002100445A1/en not_active Ceased
- 2002-06-13 US US10/480,586 patent/US20040176288A1/en not_active Abandoned
-
2009
- 2009-07-17 US US12/504,898 patent/US8728512B2/en not_active Expired - Fee Related
-
2014
- 2014-04-09 US US14/248,790 patent/US20140219991A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004532892A (ja) | 2004-10-28 |
| US8728512B2 (en) | 2014-05-20 |
| US20130280234A1 (en) | 2013-10-24 |
| WO2002100445A1 (en) | 2002-12-19 |
| ES2384099T3 (es) | 2012-06-29 |
| US20040176288A1 (en) | 2004-09-09 |
| EP1404412A1 (de) | 2004-04-07 |
| US20140219991A1 (en) | 2014-08-07 |
| JP4351041B2 (ja) | 2009-10-28 |
| EP1404412A4 (de) | 2006-03-01 |
| AU2002302192B2 (en) | 2007-08-16 |
| EP1404412B1 (de) | 2012-03-21 |
| WO2002100445A8 (en) | 2006-10-26 |
| CA2450240A1 (en) | 2002-12-19 |
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