ATE550328T1 - Thiophenderivate, die sich als den augeninnendruck senkende mittel eignen - Google Patents

Thiophenderivate, die sich als den augeninnendruck senkende mittel eignen

Info

Publication number
ATE550328T1
ATE550328T1 AT09734043T AT09734043T ATE550328T1 AT E550328 T1 ATE550328 T1 AT E550328T1 AT 09734043 T AT09734043 T AT 09734043T AT 09734043 T AT09734043 T AT 09734043T AT E550328 T1 ATE550328 T1 AT E550328T1
Authority
AT
Austria
Prior art keywords
agents
thiophene derivatives
eye pressure
lower intra
intra
Prior art date
Application number
AT09734043T
Other languages
English (en)
Inventor
David Old
Vinh Ngo
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of ATE550328T1 publication Critical patent/ATE550328T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/40—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT09734043T 2008-04-24 2009-04-22 Thiophenderivate, die sich als den augeninnendruck senkende mittel eignen ATE550328T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4772608P 2008-04-24 2008-04-24
PCT/US2009/041387 WO2009132087A1 (en) 2008-04-24 2009-04-22 Thiophene derivatives useful as ocular hypotensive agents

Publications (1)

Publication Number Publication Date
ATE550328T1 true ATE550328T1 (de) 2012-04-15

Family

ID=40775174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09734043T ATE550328T1 (de) 2008-04-24 2009-04-22 Thiophenderivate, die sich als den augeninnendruck senkende mittel eignen

Country Status (8)

Country Link
US (1) US7803798B2 (de)
EP (1) EP2288598B1 (de)
AT (1) ATE550328T1 (de)
AU (1) AU2009239371B2 (de)
CA (1) CA2722312C (de)
DK (1) DK2288598T3 (de)
ES (1) ES2381435T3 (de)
WO (1) WO2009132087A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008207991B9 (en) * 2007-01-22 2014-02-27 Allergan, Inc. Thiophene derivatives useful as ocular hypotensive agents
WO2009132093A2 (en) * 2008-04-24 2009-10-29 Allergan, Inc. Substituted arylcyclopentenes as therapeutic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437146B1 (en) 1998-09-25 2002-08-20 Fujisawa Pharmaceutical Co., Ltd. Oxazole compounds as prostaglandin e2 agonists or antagonists
BR0213911A (pt) 2001-11-05 2004-09-28 Allergan Inc Análogos de Èmega-cicloalquil 17-heteroaril prostaglandina e2 como agonistas do receptor ep2
US7091231B2 (en) 2004-12-10 2006-08-15 Allergan, Inc. 12-Aryl prostaglandin analogs
WO2007115020A2 (en) 2006-04-04 2007-10-11 Allergan, Inc. Therapeutic prostaglandin compounds for the treatment of glaucoma
US7439372B2 (en) 2006-05-03 2008-10-21 Allergan, Inc. Therapeutic compounds
EP2046714B1 (de) * 2006-06-20 2015-12-09 Allergan, Inc. Cyclpentanderivate als Mittel gegen Glaukom
US7507817B2 (en) * 2006-11-17 2009-03-24 Allergan, Inc. Prostaglandin prodrugs
AU2008207991B9 (en) * 2007-01-22 2014-02-27 Allergan, Inc. Thiophene derivatives useful as ocular hypotensive agents
WO2009132093A2 (en) * 2008-04-24 2009-10-29 Allergan, Inc. Substituted arylcyclopentenes as therapeutic agents

Also Published As

Publication number Publication date
EP2288598A1 (de) 2011-03-02
AU2009239371B2 (en) 2014-05-01
US7803798B2 (en) 2010-09-28
US20090270386A1 (en) 2009-10-29
WO2009132087A1 (en) 2009-10-29
EP2288598B1 (de) 2012-03-21
AU2009239371A1 (en) 2009-10-29
DK2288598T3 (da) 2012-04-23
ES2381435T3 (es) 2012-05-28
CA2722312A1 (en) 2009-10-29
CA2722312C (en) 2016-08-09

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