ATE552340T1 - Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln - Google Patents

Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln

Info

Publication number
ATE552340T1
ATE552340T1 AT99118785T AT99118785T ATE552340T1 AT E552340 T1 ATE552340 T1 AT E552340T1 AT 99118785 T AT99118785 T AT 99118785T AT 99118785 T AT99118785 T AT 99118785T AT E552340 T1 ATE552340 T1 AT E552340T1
Authority
AT
Austria
Prior art keywords
hepatitis
treatment
sequences
present
virus genotype
Prior art date
Application number
AT99118785T
Other languages
English (en)
Inventor
Geert Maertens
Lieven Stuyver
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Application granted granted Critical
Publication of ATE552340T1 publication Critical patent/ATE552340T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT99118785T 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln ATE552340T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93401099 1993-04-27
EP93402019 1993-08-05

Publications (1)

Publication Number Publication Date
ATE552340T1 true ATE552340T1 (de) 2012-04-15

Family

ID=26134679

Family Applications (4)

Application Number Title Priority Date Filing Date
AT99118784T ATE551423T1 (de) 1993-04-27 1994-04-27 Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika
AT99118783T ATE553201T1 (de) 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel
AT94915550T ATE373093T1 (de) 1993-04-27 1994-04-27 Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika
AT99118785T ATE552340T1 (de) 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AT99118784T ATE551423T1 (de) 1993-04-27 1994-04-27 Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika
AT99118783T ATE553201T1 (de) 1993-04-27 1994-04-27 Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel
AT94915550T ATE373093T1 (de) 1993-04-27 1994-04-27 Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika

Country Status (15)

Country Link
US (3) US6762024B2 (de)
EP (4) EP0984068B1 (de)
JP (5) JPH07508423A (de)
CN (1) CN1108030A (de)
AT (4) ATE551423T1 (de)
AU (1) AU688323B2 (de)
BR (1) BR9405334A (de)
CA (2) CA2662090A1 (de)
DE (1) DE69435023T2 (de)
ES (1) ES2294779T3 (de)
FI (1) FI946066L (de)
NO (1) NO944967L (de)
NZ (1) NZ266148A (de)
SG (1) SG50563A1 (de)
WO (1) WO1994025601A2 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2065863T3 (es) 1991-11-21 2003-09-01 Common Services Agency Analisis para la deteccion de virus de la hepatitis c.
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US7258977B1 (en) * 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
US7255997B1 (en) 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
ATE551423T1 (de) 1993-04-27 2012-04-15 Innogenetics Nv Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika
ES2231773T3 (es) 1993-05-05 2005-05-16 Common Services Agency Virus de la hepatitis c de tipo 4, 5 y 6.
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
DE69526973T3 (de) * 1994-10-21 2010-01-07 Innogenetics N.V. Sequenzen von hepatitis-c-virus genotype 7, und deren verwendung als vorbeugende, therapeutische und diagnostische mittel
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
CA2266656A1 (en) * 1996-09-17 1998-03-26 Chiron Corporation Compositions and methods for treating intracellular diseases
CZ298268B6 (cs) 1998-04-17 2007-08-08 Innogenetics N. V. Imunodiagnostický test používající redukující cinidla
DE19980730D2 (de) * 1998-04-28 2001-05-10 Wolfgang Bergter Radioimmunpharmaka zur Therapie der Hepatitis C
ES2281179T3 (es) * 1998-06-09 2007-09-16 Andrea D. Branch Nuevos peptidos del virus de la hepatitis c y usos de los mismos.
US7052830B1 (en) 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
SK287694B6 (sk) 2000-06-15 2011-06-06 Novartis Vaccines & Diagnostics, Inc. Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
AU2001292151B2 (en) * 2000-08-17 2006-05-04 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
MD2149G2 (ro) * 2001-11-23 2003-10-31 Институт Генетики И Физиологии Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
DE60326327D1 (de) * 2002-03-11 2009-04-09 Lab 21 Ltd Verfahren und zusammensetzungen zur identifikation und charakterisierung von hepatitis c
CA2484941A1 (en) 2002-07-24 2004-02-05 Intercell Ag Antigens encoded by alternative reading frame from pathogenic viruses
WO2004024182A2 (en) 2002-09-13 2004-03-25 Intercell Ag Method for isolating hepatitis c virus peptides
ES2562456T3 (es) 2003-03-24 2016-03-04 Valneva Austria Gmbh Uso de un adyuvante que induce una respuesta inmune Th1 para mejorar las respuestas inmunes
CA2530062A1 (en) 2003-07-11 2005-01-20 Intercell Ag Hcv vaccines
ES2596753T3 (es) * 2003-08-29 2017-01-11 Fujirebio Europe N.V. Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo
JP5138230B2 (ja) 2004-01-07 2013-02-06 サード・ウェーブ・テクノロジーズ・インク C型肝炎ウイルスの遺伝子型の決定方法
US20060162667A1 (en) * 2005-01-26 2006-07-27 Papadoyianis Ernest D Aquatic habitat and ecological tank
WO2007031867A2 (en) * 2005-05-25 2007-03-22 Tripep Ab A hepatitis c virus non-stru tural ns3/4a fusion gene
US7919242B2 (en) 2005-06-30 2011-04-05 Roche Molecular Systems, Inc. Light emission modifiers and their uses in nucleic acid detection, amplification and analysis
MD3300G2 (ro) * 2006-09-28 2007-11-30 Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C
WO2008046922A2 (en) * 2006-10-20 2008-04-24 Innogenetics N.V. Methodology for anaysis of sequence variations within the hcv ns5b genomic region
EP2463390A1 (de) 2006-10-20 2012-06-13 Innogenetics N.V. Methodik zur Analyse von Sequenzvariationen innerhalb des HCV-NS5B-Genombereichs
WO2008046923A2 (en) 2006-10-20 2008-04-24 Innogenetics N.V. Methodology for analysis of sequence variations within the hcv ns3/4a genomic region
WO2009022939A1 (en) * 2007-08-09 2009-02-19 Uchrezhdenie Rossiiskoi Akademii Nauk Institut Molekulyarnoi Biologii Im. V.A. Engelgardta Ran (Imb Ran) Method for identifying the genotype and subtype of hepatitis c virus on a biological microchip
WO2009022236A2 (en) * 2007-08-16 2009-02-19 Tripep Ab Immunogen platform
CN101842498A (zh) * 2007-10-30 2010-09-22 英特芒尼公司 Hcv基因型分型和表型分型
WO2009130588A2 (en) * 2008-04-22 2009-10-29 Tripep Ab Immunogen platform
WO2010112733A1 (fr) * 2009-03-30 2010-10-07 bioMérieux Support solide de détection du vhc
WO2013150450A1 (en) * 2012-04-02 2013-10-10 Universidade Do Porto Hcv homolog fragments, cell-lines and applications thereof
EP3274478B1 (de) * 2015-03-27 2020-09-23 Ortho-Clinical Diagnostics, Inc. Hcv-ns4a/modifizierte ns3-polypeptide und verwendungen davon
US10443095B2 (en) * 2016-08-02 2019-10-15 Roche Molecular Systems, Inc. Helper oligonucleotide for improved efficiency of amplification and detection/quantitation of nucleic acids

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5350671A (en) 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
BR8807310A (pt) * 1987-11-18 1990-03-13 Chiron Corp Polinucleotidio,polinucleotidio recombinante,vetor recombinante,celula hospedeira,sistema de expressao recombinante,celula transformada,polipeptidio,hcv,preparacao de polipeptidio,polipeptidio de hcv,polipeptidio purificado,polipeptidio recombinante,polipeptidio de fusao,anticorpo monoclonal,preparacao purificada de anticorpos policlonais,particula,sonda de polinucleotidio,kit anticorpo para epetopo de hcv,metodo para producao de polipeptidio,metodo para deteccao de acidos nucleicos de hcv,imunoensaio para detectar antigeno de hcv,imunoensaio para detectar anticorpos dirigidos contra antigeno de hcv,vacina para tratamento de infeccao de hcv,celula,celula infectada com hcv,metodo para producao de anticorpos para hcv e metodo para isolar cdna derivado do genoma de um agente infeccioso nao identificado
GB2236819B (en) * 1989-09-14 1993-07-14 Gen Motors France Dual master cylinder
JP3156200B2 (ja) * 1989-09-15 2001-04-16 国立予防衛生研究所長 新規のhcv分離株
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
CA2032381C (en) 1989-12-18 2006-02-21 Peter E. Highfield Viral agent
EP0435229A1 (de) * 1989-12-27 1991-07-03 Sanwa Kagaku Kenkyusho Co., Ltd. DNS-Gen von einem Non-A Non-B Hepatitis-Virus, seine Klonierung und Verwendung
WO1991014779A1 (fr) * 1990-03-28 1991-10-03 Mitsui Toatsu Chemicals, Incorporated Diagnostic du virus de l'hepatite
EP0461863A1 (de) * 1990-06-12 1991-12-18 Immuno Japan Inc. Oligonukleotid-Primer und ihre Anwendung zum Nachweis von non-A, non-B-Hepatitisvirus mit grosser Genauigkeit
NZ238681A (en) 1990-06-25 1992-03-26 Univ Osaka Res Found Non-a, non-b hepatitis virus particles and their production
ATE144993T1 (de) 1990-12-14 1996-11-15 Innogenetics Nv Synthetische antigene zum nachweis von antikörpern gegen hepatitis c-virus
EP0510952A1 (de) * 1991-04-26 1992-10-28 Immuno Japan Inc. Oligonukleotid-Primer und ihre Anwendung zum Nachweis von Non-A, Non-B-Hepatitis mit höchster Genauigkeit
HU227548B1 (en) 1991-05-08 2011-08-29 Novartis Vaccines & Diagnostic Process for production of non-naturally occuring non-hcv-1 nucleic acids, forming a hybridization product, and detecting hcv genotypes
KR0185426B1 (ko) 1991-06-24 1999-04-01 로버트 피. 블랙버언 씨형 간염 바이러스 폴리펩티드
EP0532167A3 (en) * 1991-08-09 1993-03-31 Immuno Japan Inc. Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
JPH06510191A (ja) * 1991-08-21 1994-11-17 アボツト・ラボラトリーズ Ns1に対する組換え抗原を利用したc型肝炎アッセイ
DE69232859T2 (de) 1991-09-13 2003-04-10 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden
ES2065863T3 (es) * 1991-11-21 2003-09-01 Common Services Agency Analisis para la deteccion de virus de la hepatitis c.
ES2133529T3 (es) * 1992-11-27 1999-09-16 Innogenetics Nv Procedimiento para tipificar aislamientos de hcv.
ATE551423T1 (de) 1993-04-27 2012-04-15 Innogenetics Nv Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika
ES2232815T5 (es) 1993-05-10 2009-06-15 Novartis Vaccines And Diagnostics, Inc. Metodos de tipado del virus de la hepatitis c y reactivos para usar en los mismos.
JPH06319563A (ja) 1993-05-13 1994-11-22 Imuno Japan:Kk C型肝炎ウイルス遺伝子、オリゴヌクレオチド、並びにc型 肝炎ウイルス遺伝子型判定方法
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
JP2687852B2 (ja) * 1993-10-13 1997-12-08 日本電気株式会社 半導体メモリ装置

Also Published As

Publication number Publication date
JP2004041206A (ja) 2004-02-12
DE69435023D1 (de) 2007-10-25
JP2002233389A (ja) 2002-08-20
JPH07508423A (ja) 1995-09-21
JP2002233388A (ja) 2002-08-20
WO1994025601A3 (en) 1995-03-02
CA2139100A1 (en) 1994-11-10
SG50563A1 (en) 1998-07-20
DE69435023T2 (de) 2008-09-11
CA2139100C (en) 2009-06-23
EP1004670A3 (de) 2000-09-20
CN1108030A (zh) 1995-09-06
EP0984068A3 (de) 2000-09-20
AU688323B2 (en) 1998-03-12
EP0984068B1 (de) 2012-03-28
ATE553201T1 (de) 2012-04-15
US20030008274A1 (en) 2003-01-09
EP0984068A2 (de) 2000-03-08
EP0984067A2 (de) 2000-03-08
CA2662090A1 (en) 1994-11-10
EP0984067A3 (de) 2000-09-27
EP0984067B1 (de) 2012-04-04
FI946066A7 (fi) 1994-12-23
US7195765B2 (en) 2007-03-27
ES2294779T3 (es) 2008-04-01
US6762024B2 (en) 2004-07-13
EP1004670A2 (de) 2000-05-31
NZ266148A (en) 1997-06-24
AU6722294A (en) 1994-11-21
NO944967D0 (no) 1994-12-21
FI946066A0 (fi) 1994-12-23
JP2004041207A (ja) 2004-02-12
US20030032005A1 (en) 2003-02-13
NO944967L (no) 1994-12-21
EP0651807A1 (de) 1995-05-10
ATE551423T1 (de) 2012-04-15
BR9405334A (pt) 1999-05-25
US7157226B1 (en) 2007-01-02
FI946066L (fi) 1994-12-23
EP0651807B1 (de) 2007-09-12
EP1004670B1 (de) 2012-04-11
ATE373093T1 (de) 2007-09-15
WO1994025601A2 (en) 1994-11-10

Similar Documents

Publication Publication Date Title
ATE553201T1 (de) Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel
Gwack et al. Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein
DK0804584T3 (da) Sekvenser af hepatitis C virus genotype 7 og deres anvendelse som profylaktiske, terapeutiske og diagnostiske midler
ATE507312T1 (de) Nachweis und typisierung das hepatitis c virus (hcv) mittels 5'utr und ns5 nukleinsäuresequenzen
WO1992019743A3 (en) Hcv genomic sequences for diagnostics and therapeutics
DK0770679T4 (da) HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
CA2230452A1 (en) Novel 3' terminal sequence of hepatitis c virus genome and diagnostic and therapeutic uses thereof
ATE244729T1 (de) Verfahren zur identifizierung von wirkstoffen gegen hcv durch verwendung von strukturkoordinaten der hepatitis-c-virus- protease
DE69839557D1 (de) Klonierte genome von infektiösen hepatitis c viren und deren verwendungen
NZ319786A (en) HCV NS3 protein fragments with helicase activity and improved solubility
DE69029092D1 (de) Synthetische Antigene zum Nachweis von Antikörpern gegen Hepatitis C-Virus
DE69232906T2 (de) Detektion des Hepatis-C Virus.
ATE423785T1 (de) Verfahren und zusammensetzungen zur identifikation und charakterisierung von hepatitis c
EP1878797A3 (de) Antigene Peptide zur Gruppierung des Hepatitis-C-Virus, Kit damit und Verfahren zur Gruppierung unter Verwendung dieses Kits
DE69125066D1 (de) cDNS-Sequenz und Detektion des Hepatitis C-Virus
DK0551275T3 (da) Non-A non-B sekvenser
TW369600B (en) Antigenic peptides for grouping hepatitis C virus, kit comprising the same and methods for its grouping the same