ATE552340T1 - Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln - Google Patents
Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittelnInfo
- Publication number
- ATE552340T1 ATE552340T1 AT99118785T AT99118785T ATE552340T1 AT E552340 T1 ATE552340 T1 AT E552340T1 AT 99118785 T AT99118785 T AT 99118785T AT 99118785 T AT99118785 T AT 99118785T AT E552340 T1 ATE552340 T1 AT E552340T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis
- treatment
- sequences
- present
- virus genotype
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93401099 | 1993-04-27 | ||
| EP93402019 | 1993-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE552340T1 true ATE552340T1 (de) | 2012-04-15 |
Family
ID=26134679
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99118784T ATE551423T1 (de) | 1993-04-27 | 1994-04-27 | Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika |
| AT99118783T ATE553201T1 (de) | 1993-04-27 | 1994-04-27 | Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel |
| AT94915550T ATE373093T1 (de) | 1993-04-27 | 1994-04-27 | Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika |
| AT99118785T ATE552340T1 (de) | 1993-04-27 | 1994-04-27 | Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismitteln |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99118784T ATE551423T1 (de) | 1993-04-27 | 1994-04-27 | Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika |
| AT99118783T ATE553201T1 (de) | 1993-04-27 | 1994-04-27 | Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel |
| AT94915550T ATE373093T1 (de) | 1993-04-27 | 1994-04-27 | Sequenzen der genotype des hepatitis-c-virus sowie ihre verwendung als arzneimitteln und diagnostika |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US6762024B2 (de) |
| EP (4) | EP0984068B1 (de) |
| JP (5) | JPH07508423A (de) |
| CN (1) | CN1108030A (de) |
| AT (4) | ATE551423T1 (de) |
| AU (1) | AU688323B2 (de) |
| BR (1) | BR9405334A (de) |
| CA (2) | CA2662090A1 (de) |
| DE (1) | DE69435023T2 (de) |
| ES (1) | ES2294779T3 (de) |
| FI (1) | FI946066L (de) |
| NO (1) | NO944967L (de) |
| NZ (1) | NZ266148A (de) |
| SG (1) | SG50563A1 (de) |
| WO (1) | WO1994025601A2 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2065863T3 (es) | 1991-11-21 | 2003-09-01 | Common Services Agency | Analisis para la deteccion de virus de la hepatitis c. |
| US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
| US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
| US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US7258977B1 (en) * | 1992-11-27 | 2007-08-21 | Innogenetics N.V. | Process for typing of HCV isolates |
| US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
| ATE551423T1 (de) | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika |
| ES2231773T3 (es) | 1993-05-05 | 2005-05-16 | Common Services Agency | Virus de la hepatitis c de tipo 4, 5 y 6. |
| US5514539A (en) * | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
| US5882852A (en) * | 1993-06-29 | 1999-03-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates |
| US7070790B1 (en) | 1993-06-29 | 2006-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
| DE69526973T3 (de) * | 1994-10-21 | 2010-01-07 | Innogenetics N.V. | Sequenzen von hepatitis-c-virus genotype 7, und deren verwendung als vorbeugende, therapeutische und diagnostische mittel |
| US5851759A (en) * | 1996-04-19 | 1998-12-22 | Chiron Corporation | Heteroduplex tracking assay (HTA) for genotyping HCV |
| CA2266656A1 (en) * | 1996-09-17 | 1998-03-26 | Chiron Corporation | Compositions and methods for treating intracellular diseases |
| CZ298268B6 (cs) | 1998-04-17 | 2007-08-08 | Innogenetics N. V. | Imunodiagnostický test používající redukující cinidla |
| DE19980730D2 (de) * | 1998-04-28 | 2001-05-10 | Wolfgang Bergter | Radioimmunpharmaka zur Therapie der Hepatitis C |
| ES2281179T3 (es) * | 1998-06-09 | 2007-09-16 | Andrea D. Branch | Nuevos peptidos del virus de la hepatitis c y usos de los mismos. |
| US7052830B1 (en) | 1998-06-09 | 2006-05-30 | Branch Andrea D | Hepatitis C virus peptides and uses thereof |
| SK287694B6 (sk) | 2000-06-15 | 2011-06-06 | Novartis Vaccines & Diagnostics, Inc. | Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku |
| US6680059B2 (en) * | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US7022830B2 (en) * | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| AU2001292151B2 (en) * | 2000-08-17 | 2006-05-04 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US7196183B2 (en) | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
| MD2149G2 (ro) * | 2001-11-23 | 2003-10-31 | Институт Генетики И Физиологии Растений Академии Наук Молдовы | Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C |
| DE60326327D1 (de) * | 2002-03-11 | 2009-04-09 | Lab 21 Ltd | Verfahren und zusammensetzungen zur identifikation und charakterisierung von hepatitis c |
| CA2484941A1 (en) | 2002-07-24 | 2004-02-05 | Intercell Ag | Antigens encoded by alternative reading frame from pathogenic viruses |
| WO2004024182A2 (en) | 2002-09-13 | 2004-03-25 | Intercell Ag | Method for isolating hepatitis c virus peptides |
| ES2562456T3 (es) | 2003-03-24 | 2016-03-04 | Valneva Austria Gmbh | Uso de un adyuvante que induce una respuesta inmune Th1 para mejorar las respuestas inmunes |
| CA2530062A1 (en) | 2003-07-11 | 2005-01-20 | Intercell Ag | Hcv vaccines |
| ES2596753T3 (es) * | 2003-08-29 | 2017-01-11 | Fujirebio Europe N.V. | Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo |
| JP5138230B2 (ja) | 2004-01-07 | 2013-02-06 | サード・ウェーブ・テクノロジーズ・インク | C型肝炎ウイルスの遺伝子型の決定方法 |
| US20060162667A1 (en) * | 2005-01-26 | 2006-07-27 | Papadoyianis Ernest D | Aquatic habitat and ecological tank |
| WO2007031867A2 (en) * | 2005-05-25 | 2007-03-22 | Tripep Ab | A hepatitis c virus non-stru tural ns3/4a fusion gene |
| US7919242B2 (en) | 2005-06-30 | 2011-04-05 | Roche Molecular Systems, Inc. | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis |
| MD3300G2 (ro) * | 2006-09-28 | 2007-11-30 | Институт Генетики, Физиологии И Защиты Растений Академии Наук Молдовы | Primer oligonucleotidic pentru depistarea ARN-ului virusului hepatitei C |
| WO2008046922A2 (en) * | 2006-10-20 | 2008-04-24 | Innogenetics N.V. | Methodology for anaysis of sequence variations within the hcv ns5b genomic region |
| EP2463390A1 (de) | 2006-10-20 | 2012-06-13 | Innogenetics N.V. | Methodik zur Analyse von Sequenzvariationen innerhalb des HCV-NS5B-Genombereichs |
| WO2008046923A2 (en) | 2006-10-20 | 2008-04-24 | Innogenetics N.V. | Methodology for analysis of sequence variations within the hcv ns3/4a genomic region |
| WO2009022939A1 (en) * | 2007-08-09 | 2009-02-19 | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Molekulyarnoi Biologii Im. V.A. Engelgardta Ran (Imb Ran) | Method for identifying the genotype and subtype of hepatitis c virus on a biological microchip |
| WO2009022236A2 (en) * | 2007-08-16 | 2009-02-19 | Tripep Ab | Immunogen platform |
| CN101842498A (zh) * | 2007-10-30 | 2010-09-22 | 英特芒尼公司 | Hcv基因型分型和表型分型 |
| WO2009130588A2 (en) * | 2008-04-22 | 2009-10-29 | Tripep Ab | Immunogen platform |
| WO2010112733A1 (fr) * | 2009-03-30 | 2010-10-07 | bioMérieux | Support solide de détection du vhc |
| WO2013150450A1 (en) * | 2012-04-02 | 2013-10-10 | Universidade Do Porto | Hcv homolog fragments, cell-lines and applications thereof |
| EP3274478B1 (de) * | 2015-03-27 | 2020-09-23 | Ortho-Clinical Diagnostics, Inc. | Hcv-ns4a/modifizierte ns3-polypeptide und verwendungen davon |
| US10443095B2 (en) * | 2016-08-02 | 2019-10-15 | Roche Molecular Systems, Inc. | Helper oligonucleotide for improved efficiency of amplification and detection/quantitation of nucleic acids |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5350671A (en) | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
| BR8807310A (pt) * | 1987-11-18 | 1990-03-13 | Chiron Corp | Polinucleotidio,polinucleotidio recombinante,vetor recombinante,celula hospedeira,sistema de expressao recombinante,celula transformada,polipeptidio,hcv,preparacao de polipeptidio,polipeptidio de hcv,polipeptidio purificado,polipeptidio recombinante,polipeptidio de fusao,anticorpo monoclonal,preparacao purificada de anticorpos policlonais,particula,sonda de polinucleotidio,kit anticorpo para epetopo de hcv,metodo para producao de polipeptidio,metodo para deteccao de acidos nucleicos de hcv,imunoensaio para detectar antigeno de hcv,imunoensaio para detectar anticorpos dirigidos contra antigeno de hcv,vacina para tratamento de infeccao de hcv,celula,celula infectada com hcv,metodo para producao de anticorpos para hcv e metodo para isolar cdna derivado do genoma de um agente infeccioso nao identificado |
| GB2236819B (en) * | 1989-09-14 | 1993-07-14 | Gen Motors France | Dual master cylinder |
| JP3156200B2 (ja) * | 1989-09-15 | 2001-04-16 | 国立予防衛生研究所長 | 新規のhcv分離株 |
| US5372928A (en) * | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
| CA2032381C (en) | 1989-12-18 | 2006-02-21 | Peter E. Highfield | Viral agent |
| EP0435229A1 (de) * | 1989-12-27 | 1991-07-03 | Sanwa Kagaku Kenkyusho Co., Ltd. | DNS-Gen von einem Non-A Non-B Hepatitis-Virus, seine Klonierung und Verwendung |
| WO1991014779A1 (fr) * | 1990-03-28 | 1991-10-03 | Mitsui Toatsu Chemicals, Incorporated | Diagnostic du virus de l'hepatite |
| EP0461863A1 (de) * | 1990-06-12 | 1991-12-18 | Immuno Japan Inc. | Oligonukleotid-Primer und ihre Anwendung zum Nachweis von non-A, non-B-Hepatitisvirus mit grosser Genauigkeit |
| NZ238681A (en) | 1990-06-25 | 1992-03-26 | Univ Osaka Res Found | Non-a, non-b hepatitis virus particles and their production |
| ATE144993T1 (de) | 1990-12-14 | 1996-11-15 | Innogenetics Nv | Synthetische antigene zum nachweis von antikörpern gegen hepatitis c-virus |
| EP0510952A1 (de) * | 1991-04-26 | 1992-10-28 | Immuno Japan Inc. | Oligonukleotid-Primer und ihre Anwendung zum Nachweis von Non-A, Non-B-Hepatitis mit höchster Genauigkeit |
| HU227548B1 (en) | 1991-05-08 | 2011-08-29 | Novartis Vaccines & Diagnostic | Process for production of non-naturally occuring non-hcv-1 nucleic acids, forming a hybridization product, and detecting hcv genotypes |
| KR0185426B1 (ko) | 1991-06-24 | 1999-04-01 | 로버트 피. 블랙버언 | 씨형 간염 바이러스 폴리펩티드 |
| EP0532167A3 (en) * | 1991-08-09 | 1993-03-31 | Immuno Japan Inc. | Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
| JPH06510191A (ja) * | 1991-08-21 | 1994-11-17 | アボツト・ラボラトリーズ | Ns1に対する組換え抗原を利用したc型肝炎アッセイ |
| DE69232859T2 (de) | 1991-09-13 | 2003-04-10 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden |
| ES2065863T3 (es) * | 1991-11-21 | 2003-09-01 | Common Services Agency | Analisis para la deteccion de virus de la hepatitis c. |
| ES2133529T3 (es) * | 1992-11-27 | 1999-09-16 | Innogenetics Nv | Procedimiento para tipificar aislamientos de hcv. |
| ATE551423T1 (de) | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika |
| ES2232815T5 (es) | 1993-05-10 | 2009-06-15 | Novartis Vaccines And Diagnostics, Inc. | Metodos de tipado del virus de la hepatitis c y reactivos para usar en los mismos. |
| JPH06319563A (ja) | 1993-05-13 | 1994-11-22 | Imuno Japan:Kk | C型肝炎ウイルス遺伝子、オリゴヌクレオチド、並びにc型 肝炎ウイルス遺伝子型判定方法 |
| US5514539A (en) * | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
| US5882852A (en) | 1993-06-29 | 1999-03-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates |
| JP2687852B2 (ja) * | 1993-10-13 | 1997-12-08 | 日本電気株式会社 | 半導体メモリ装置 |
-
1994
- 1994-04-27 AT AT99118784T patent/ATE551423T1/de active
- 1994-04-27 AU AU67222/94A patent/AU688323B2/en not_active Expired
- 1994-04-27 EP EP99118784A patent/EP0984068B1/de not_active Expired - Lifetime
- 1994-04-27 JP JP6523877A patent/JPH07508423A/ja active Pending
- 1994-04-27 US US09/878,281 patent/US6762024B2/en not_active Expired - Fee Related
- 1994-04-27 CA CA002662090A patent/CA2662090A1/en not_active Abandoned
- 1994-04-27 EP EP99118783A patent/EP1004670B1/de not_active Expired - Lifetime
- 1994-04-27 NZ NZ266148A patent/NZ266148A/en not_active IP Right Cessation
- 1994-04-27 BR BR9405334A patent/BR9405334A/pt not_active Application Discontinuation
- 1994-04-27 ES ES94915550T patent/ES2294779T3/es not_active Expired - Lifetime
- 1994-04-27 EP EP94915550A patent/EP0651807B1/de not_active Expired - Lifetime
- 1994-04-27 EP EP99118785A patent/EP0984067B1/de not_active Expired - Lifetime
- 1994-04-27 AT AT99118783T patent/ATE553201T1/de active
- 1994-04-27 CN CN94190232A patent/CN1108030A/zh active Pending
- 1994-04-27 US US08/362,455 patent/US7157226B1/en not_active Expired - Fee Related
- 1994-04-27 WO PCT/EP1994/001323 patent/WO1994025601A2/en not_active Ceased
- 1994-04-27 CA CA002139100A patent/CA2139100C/en not_active Expired - Lifetime
- 1994-04-27 AT AT94915550T patent/ATE373093T1/de active
- 1994-04-27 AT AT99118785T patent/ATE552340T1/de active
- 1994-04-27 SG SG1996005012A patent/SG50563A1/en unknown
- 1994-04-27 FI FI946066A patent/FI946066L/fi unknown
- 1994-04-27 DE DE69435023T patent/DE69435023T2/de not_active Expired - Lifetime
- 1994-12-21 NO NO944967A patent/NO944967L/no not_active Application Discontinuation
-
2001
- 2001-07-06 US US09/899,046 patent/US7195765B2/en not_active Expired - Fee Related
- 2001-11-21 JP JP2001356707A patent/JP2002233389A/ja active Pending
- 2001-11-21 JP JP2001355654A patent/JP2002233388A/ja active Pending
-
2003
- 2003-07-08 JP JP2003272022A patent/JP2004041206A/ja not_active Withdrawn
- 2003-07-09 JP JP2003272151A patent/JP2004041207A/ja not_active Withdrawn
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