ATE554099T1 - Assays auf zellbasis unter anwendung von spannung und calciumfarbstoffen - Google Patents

Assays auf zellbasis unter anwendung von spannung und calciumfarbstoffen

Info

Publication number
ATE554099T1
ATE554099T1 AT04800492T AT04800492T ATE554099T1 AT E554099 T1 ATE554099 T1 AT E554099T1 AT 04800492 T AT04800492 T AT 04800492T AT 04800492 T AT04800492 T AT 04800492T AT E554099 T1 ATE554099 T1 AT E554099T1
Authority
AT
Austria
Prior art keywords
protein
cell
disclosed
voltage
based assay
Prior art date
Application number
AT04800492T
Other languages
English (en)
Inventor
Yong Yao
Liang Cao
Jianming Lu
Isabel Llorente
Original Assignee
Atto Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Atto Bioscience Inc filed Critical Atto Bioscience Inc
Application granted granted Critical
Publication of ATE554099T1 publication Critical patent/ATE554099T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Secondary Cells (AREA)
AT04800492T 2003-10-30 2004-11-01 Assays auf zellbasis unter anwendung von spannung und calciumfarbstoffen ATE554099T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51544203P 2003-10-30 2003-10-30
US58901204P 2004-07-20 2004-07-20
PCT/US2004/036022 WO2005041758A2 (en) 2003-10-30 2004-11-01 Novel cell-based assays employing voltage and calcium dyes

Publications (1)

Publication Number Publication Date
ATE554099T1 true ATE554099T1 (de) 2012-05-15

Family

ID=34555989

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04800492T ATE554099T1 (de) 2003-10-30 2004-11-01 Assays auf zellbasis unter anwendung von spannung und calciumfarbstoffen

Country Status (5)

Country Link
EP (1) EP1682577B1 (de)
JP (1) JP4848282B2 (de)
AT (1) ATE554099T1 (de)
DK (1) DK1682577T3 (de)
WO (1) WO2005041758A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2822594A1 (en) 2010-12-24 2012-06-28 Otsuka Pharmaceutical Co., Ltd. Bioassay method for detecting physiologically active substance

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660790A (en) * 1996-08-13 1997-08-26 Litmus Concepts, Inc. PH and amine test elements
CA2293254A1 (en) * 1997-06-13 1998-12-23 Allelix Biopharmaceuticals Inc. Assay methods and compositions useful for measuring receptor ligand binding
US7115377B2 (en) * 2001-10-26 2006-10-03 Atto Bioscience, Inc. Cell-based assays for G-protein-coupled receptor-mediated activities
US7166463B2 (en) * 2001-11-16 2007-01-23 The Regents Of The University Of Colorado Nucleic acids encoding modified olfactory cyclic nucleotide gated ion channels

Also Published As

Publication number Publication date
EP1682577B1 (de) 2012-04-18
JP2007509631A (ja) 2007-04-19
EP1682577A2 (de) 2006-07-26
WO2005041758A3 (en) 2006-04-13
EP1682577A4 (de) 2007-05-09
DK1682577T3 (da) 2012-07-16
WO2005041758A2 (en) 2005-05-12
JP4848282B2 (ja) 2011-12-28
WO2005041758A9 (en) 2005-06-09

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