ATE554384T1 - Verfahren und kit für den nachweis heparinabhängiger antikörper und die diagnose von heparin-potenzierten immun- bzw. autoimmunerkrankungen wie etwa heparin-induzierte thrombopenie - Google Patents
Verfahren und kit für den nachweis heparinabhängiger antikörper und die diagnose von heparin-potenzierten immun- bzw. autoimmunerkrankungen wie etwa heparin-induzierte thrombopenieInfo
- Publication number
- ATE554384T1 ATE554384T1 AT07788927T AT07788927T ATE554384T1 AT E554384 T1 ATE554384 T1 AT E554384T1 AT 07788927 T AT07788927 T AT 07788927T AT 07788927 T AT07788927 T AT 07788927T AT E554384 T1 ATE554384 T1 AT E554384T1
- Authority
- AT
- Austria
- Prior art keywords
- heparin
- substance
- immune
- diagnosis
- detection
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 206010043554 thrombocytopenia Diseases 0.000 title abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 208000026278 immune system disease Diseases 0.000 title 1
- 239000000126 substance Substances 0.000 abstract 11
- 229960002897 heparin Drugs 0.000 abstract 10
- 229920000669 heparin Polymers 0.000 abstract 10
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 9
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000411 inducer Substances 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/22—Haematology
- G01N2800/222—Platelet disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0605662A FR2902884B1 (fr) | 2006-06-23 | 2006-06-23 | Procede pour la detection des anticorps heparine-dependants et le diagnostic des pathologies immunes ou auto-immnues potentialisees par l'heparine telle que la thrombopenie induite par l'heparine |
| PCT/FR2007/001049 WO2007147983A1 (fr) | 2006-06-23 | 2007-06-25 | Procede et necessaire pour la detection des anticorps heparine-dependants et le diagnostic des pathologies immunes ou auto-immunes potentialisees par l'heparine telle que la thrombopenie induite par l'heparine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554384T1 true ATE554384T1 (de) | 2012-05-15 |
Family
ID=37888414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07788927T ATE554384T1 (de) | 2006-06-23 | 2007-06-25 | Verfahren und kit für den nachweis heparinabhängiger antikörper und die diagnose von heparin-potenzierten immun- bzw. autoimmunerkrankungen wie etwa heparin-induzierte thrombopenie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9097731B2 (de) |
| EP (1) | EP2030017B1 (de) |
| AT (1) | ATE554384T1 (de) |
| AU (1) | AU2007262869A1 (de) |
| CA (1) | CA2655582C (de) |
| FR (1) | FR2902884B1 (de) |
| WO (1) | WO2007147983A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120040373A1 (en) * | 2010-08-13 | 2012-02-16 | Mariano Ubeda | Integrated Diagnosis of Heparin-Induced Thrombocytopenia |
| WO2012170435A2 (en) | 2011-06-09 | 2012-12-13 | Gen-Probe Incorporated | Diagnostic devices, methods and systems for detecting platelet factor 4 (pf4)/heparin antibodies |
| US11293916B2 (en) * | 2015-12-11 | 2022-04-05 | Peking University First Hospital | Method and kit for detecting concentration of factor H |
| US12366584B2 (en) | 2020-04-21 | 2025-07-22 | Retham Technologies, Inc. | Identification of platelet activating antibodies |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5466582A (en) * | 1990-08-09 | 1995-11-14 | Serbio | Thrombocytopenia determination |
| US5753445A (en) * | 1994-04-26 | 1998-05-19 | The Mount Sinai Medical Center Of The City University Of New York | Test for the detection of anti-heparin antibodies |
| US5972717A (en) * | 1995-05-10 | 1999-10-26 | The Blood Center Research Foundation, Inc. | Method and kit for detecting heparin induced thrombocytopenia |
| US5972718A (en) * | 1996-02-28 | 1999-10-26 | The Blood Center Research Foundation | Method of detecting heparin-induced thrombocytopenia |
| CA2401411A1 (en) * | 1999-08-30 | 2001-03-08 | Mustapha Abdelouahed | Diagnostic assay for type 2 heparin-induced thrombocytopenia |
| WO2006042089A2 (en) * | 2004-10-04 | 2006-04-20 | Akers Biosciences, Inc. | Methods and kits for detecting heparin/platelet factor 4 antibodies |
-
2006
- 2006-06-23 FR FR0605662A patent/FR2902884B1/fr not_active Expired - Fee Related
-
2007
- 2007-06-25 AT AT07788927T patent/ATE554384T1/de active
- 2007-06-25 CA CA2655582A patent/CA2655582C/fr not_active Expired - Fee Related
- 2007-06-25 WO PCT/FR2007/001049 patent/WO2007147983A1/fr not_active Ceased
- 2007-06-25 EP EP07788927A patent/EP2030017B1/de not_active Not-in-force
- 2007-06-25 AU AU2007262869A patent/AU2007262869A1/en not_active Abandoned
- 2007-06-25 US US12/305,224 patent/US9097731B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2902884A1 (fr) | 2007-12-28 |
| WO2007147983A1 (fr) | 2007-12-27 |
| EP2030017B1 (de) | 2012-04-18 |
| US20100015647A1 (en) | 2010-01-21 |
| CA2655582A1 (fr) | 2007-12-27 |
| AU2007262869A1 (en) | 2007-12-27 |
| FR2902884B1 (fr) | 2008-12-26 |
| EP2030017A1 (de) | 2009-03-04 |
| US9097731B2 (en) | 2015-08-04 |
| CA2655582C (fr) | 2014-12-30 |
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