ATE555636T1 - Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial - Google Patents
Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterialInfo
- Publication number
- ATE555636T1 ATE555636T1 AT08728244T AT08728244T ATE555636T1 AT E555636 T1 ATE555636 T1 AT E555636T1 AT 08728244 T AT08728244 T AT 08728244T AT 08728244 T AT08728244 T AT 08728244T AT E555636 T1 ATE555636 T1 AT E555636T1
- Authority
- AT
- Austria
- Prior art keywords
- antioxidant
- polymeric materials
- polymer material
- linked polymer
- resistant cross
- Prior art date
Links
- 229920006037 cross link polymer Polymers 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002861 polymer material Substances 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 abstract 5
- 235000006708 antioxidants Nutrition 0.000 abstract 5
- 239000000463 material Substances 0.000 abstract 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 4
- 230000003078 antioxidant effect Effects 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 229930003427 Vitamin E Natural products 0.000 abstract 2
- 238000010828 elution Methods 0.000 abstract 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 2
- 229960001295 tocopherol Drugs 0.000 abstract 2
- 239000011732 tocopherol Substances 0.000 abstract 2
- 239000011709 vitamin E Substances 0.000 abstract 2
- 235000019165 vitamin E Nutrition 0.000 abstract 2
- 229940046009 vitamin E Drugs 0.000 abstract 2
- 238000004132 cross linking Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- -1 for example Substances 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F10/00—Homopolymers and copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
- C08F10/02—Ethene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/505—Stabilizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/003—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
- B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
- B29C43/18—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. compression moulding around inserts or for coating articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C71/00—After-treatment of articles without altering their shape; Apparatus therefor
- B29C71/04—After-treatment of articles without altering their shape; Apparatus therefor by wave energy or particle radiation, e.g. for curing or vulcanising preformed articles
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/28—Treatment by wave energy or particle radiation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/15—Heterocyclic compounds having oxygen in the ring
- C08K5/151—Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
- C08K5/1545—Six-membered rings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
- B29K2023/04—Polymers of ethylene
- B29K2023/06—PE, i.e. polyethylene
- B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
- B29K2023/0683—UHMWPE, i.e. ultra high molecular weight polyethylene
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/06—Condition, form or state of moulded material or of the material to be shaped containing reinforcements, fillers or inserts
- B29K2105/20—Inserts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0056—Biocompatible, e.g. biopolymers or bioelastomers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F110/00—Homopolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
- C08F110/02—Ethene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2323/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
- C08J2323/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
- C08J2323/04—Homopolymers or copolymers of ethene
- C08J2323/06—Polyethene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/012—Additives improving oxygen scavenging properties
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Materials For Medical Uses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Prostheses (AREA)
- Heating, Cooling, Or Curing Plastics Or The Like In General (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88652707P | 2007-01-25 | 2007-01-25 | |
| US88903707P | 2007-02-09 | 2007-02-09 | |
| US89234607P | 2007-03-01 | 2007-03-01 | |
| PCT/US2008/051982 WO2008092047A1 (en) | 2007-01-25 | 2008-01-25 | Methods for making oxidation-resistant cross-linked polymeric materials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE555636T1 true ATE555636T1 (de) | 2012-05-15 |
Family
ID=39644889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08728244T ATE555636T1 (de) | 2007-01-25 | 2008-01-25 | Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8293811B2 (de) |
| EP (4) | EP2456283B1 (de) |
| JP (1) | JP5535650B2 (de) |
| AT (1) | ATE555636T1 (de) |
| AU (1) | AU2008207807B2 (de) |
| CA (1) | CA2674955C (de) |
| ES (1) | ES2385317T3 (de) |
| WO (1) | WO2008092047A1 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8426486B2 (en) * | 2004-02-03 | 2013-04-23 | The General Hospital Corporation | Highly crystalline cross-linked oxidation-resistant polyethylene |
| ATE449618T1 (de) | 2005-08-18 | 2009-12-15 | Zimmer Gmbh | Ultrahochmolekulare polyethylen-artikel und verfahren zur herstellung von ultrahochmolekularen polyethylen-artikeln |
| EP2456283B1 (de) | 2007-01-25 | 2015-12-16 | The General Hospital Corporation | Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial |
| WO2008101116A1 (en) * | 2007-02-14 | 2008-08-21 | Brigham And Women's Hospital, Inc. | Crosslinked polymers and methods of making the same |
| AU2008222967B2 (en) * | 2007-03-02 | 2012-12-13 | Cambridge Polymer Group, Inc. | Cross-linking of antioxidant-containing polymers |
| EP2578248B1 (de) | 2007-04-10 | 2021-05-19 | Zimmer, Inc. | Antioxidans-stabilisiertes, vernetztes Polyethylen mit ultrahohem Molekulargewicht für Medizingeräteanwendungen |
| US8664290B2 (en) | 2007-04-10 | 2014-03-04 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications |
| US8652212B2 (en) | 2008-01-30 | 2014-02-18 | Zimmer, Inc. | Orthopedic component of low stiffness |
| MX2010013737A (es) | 2008-06-13 | 2011-04-11 | Michael J Parrella | Sistema y metodo de captura de calor geotermico de un pozo perforado para generar electricidad. |
| JP5311457B2 (ja) * | 2008-06-20 | 2013-10-09 | ナカシマメディカル株式会社 | 人工関節用摺動部材の成形方法及びこの方法によって成形された人工関節用摺動部材 |
| US20100270001A1 (en) * | 2008-08-05 | 2010-10-28 | Parrella Michael J | System and method of maximizing grout heat conductibility and increasing caustic resistance |
| US9423158B2 (en) | 2008-08-05 | 2016-08-23 | Michael J. Parrella | System and method of maximizing heat transfer at the bottom of a well using heat conductive components and a predictive model |
| WO2010057644A1 (en) | 2008-11-20 | 2010-05-27 | Zimmer Gmbh | Polyethylene materials |
| WO2010096771A2 (en) | 2009-02-20 | 2010-08-26 | The General Hospital Corporation Dba | High temperature melting |
| CN102458492B (zh) * | 2009-05-04 | 2015-11-25 | 史密夫和内修有限公司 | 在uhmwpe中共混多种添加剂的协同作用 |
| GB0922339D0 (en) | 2009-12-21 | 2010-02-03 | Mcminn Derek J W | Acetabular cup prothesis and introducer thereof |
| JP2011173979A (ja) * | 2010-02-24 | 2011-09-08 | Nakashima Medical Co Ltd | 超高分子量ポリエチレンの成形品 |
| JP5765797B2 (ja) * | 2010-02-24 | 2015-08-19 | ナカシマメディカル株式会社 | 超高分子量ポリエチレンの成形品 |
| US8399535B2 (en) | 2010-06-10 | 2013-03-19 | Zimmer, Inc. | Polymer [[s]] compositions including an antioxidant |
| US8966868B2 (en) * | 2011-05-09 | 2015-03-03 | Abbott Cardiovascular Systems Inc. | Methods of stabilizing molecular weight of polymer stents after sterilization |
| AU2012281077A1 (en) | 2011-07-13 | 2014-03-06 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Methods and devices for knee joint replacement with anterior cruciate ligament substitution |
| AU2013243693B2 (en) * | 2012-04-04 | 2016-10-20 | The General Hospital Corporation | Peroxide cross-linking of polymeric materials in the presence of antioxidants |
| US10000305B2 (en) | 2012-05-11 | 2018-06-19 | The General Hospital Corporation | Antioxidant-stabilized joint implants |
| WO2014025636A1 (en) * | 2012-08-06 | 2014-02-13 | The General Hospital Corporation | Spatial control of additives by high temperature |
| BR112015006916A2 (pt) | 2012-09-27 | 2017-07-04 | The General Hospital Corp D/B/A Massachusetts General Hospital | cabeças femorais, inserções móveis, componentes acetabulares e junções modulares para implantes ortopédicos e métodos para uso de cabeças femorais, inserções móveis, componentes acetabulares e junções modulares para implantes ortopédicos |
| EP3052562B1 (de) | 2013-10-01 | 2017-11-08 | Zimmer, Inc. | Polymerzusammensetzungen, enthaltend ein oder mehrere geschützte antioxidantien |
| CA2927056A1 (en) | 2013-10-17 | 2015-04-23 | The General Hospital Corporation | Peroxide cross-linking and high temperature melting |
| US10184031B2 (en) * | 2014-03-12 | 2019-01-22 | Zimmer, Inc. | Melt-stabilized ultra high molecular weight polyethylene and method of making the same |
| EP3227360B1 (de) | 2014-12-03 | 2024-10-16 | Zimmer, Inc. | Mit antioxidationsmittel infundiertes polyethylen mit ultrahohem molekulargewicht |
| JP2016173328A (ja) * | 2015-03-17 | 2016-09-29 | 日本ポリプロ株式会社 | ポリオレフィン中に含まれる添加剤の定量分析方法 |
| WO2017083476A1 (en) | 2015-11-12 | 2017-05-18 | The General Hospital Corporation | Methods of making therapeutic polymeric material |
| AU2017214566A1 (en) | 2016-02-05 | 2018-08-23 | The General Hospital Corporation | Drug eluting polymer composed of biodegradable polymers applied to surface of medical device |
| WO2017192347A1 (en) | 2016-05-02 | 2017-11-09 | The General Hospital Corporation | Implant surfaces for pain control |
| DE102016110500B4 (de) * | 2016-06-07 | 2019-03-14 | Karl Leibinger Medizintechnik Gmbh & Co. Kg | Implantatherstellverfahren mittels additivem selektivem Lasersintern und Implantat |
| US11667762B2 (en) | 2017-08-29 | 2023-06-06 | The General Hospital Corporation | UV-initiated reactions in polymeric materials |
| US11376128B2 (en) | 2018-12-31 | 2022-07-05 | Depuy Ireland Unlimited Company | Acetabular orthopaedic prosthesis and method |
| US12171666B2 (en) | 2019-12-10 | 2024-12-24 | Depuy Ireland Unlimited Company | Metal reinforced acetabular shell liner |
| US11291549B2 (en) | 2019-12-11 | 2022-04-05 | Depuy Ireland Unlimited Company | Ceramic acetabular shell liners with augments |
| US11628066B2 (en) | 2019-12-11 | 2023-04-18 | Depuy Ireland Unlimited Company | Ceramic acetabular shell liner with a metal ring having a lead-in surface |
| US11952439B2 (en) * | 2020-06-25 | 2024-04-09 | b-ONE Medical (Suzhou) Co., Ltd. | Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof |
| WO2022006356A1 (en) | 2020-06-30 | 2022-01-06 | Texas Tech University System | Method and apparatus for collection of fluid samples |
| US11970600B2 (en) | 2021-03-31 | 2024-04-30 | The General Hospital Corporation | Di-cumyl peroxide crosslinking of UHMWPE |
| US12042389B2 (en) | 2021-04-30 | 2024-07-23 | Depuy Ireland Unlimited Company | Apparatus and method for installing an acetabular liner on an acetabular cup |
| US12376964B2 (en) | 2021-04-30 | 2025-08-05 | Depuy Ireland Unlimited Company | Apparatus and method for locking an acetabular liner to an acetabular cup |
| CN114292431A (zh) * | 2021-11-22 | 2022-04-08 | 苏州微创关节医疗科技有限公司 | 超高分子量聚乙烯植入体及其制备方法和关节假体 |
| WO2023201037A2 (en) * | 2022-04-15 | 2023-10-19 | Anuj Bellare | Methods for inducing crystallization in crystallizable polymers, and articles therefrom |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3011505A (en) | 1957-02-08 | 1961-12-05 | Askania Regulator Co | Ejector for use in a jet-type hydraulic relay regulator |
| US3879400A (en) | 1973-11-16 | 1975-04-22 | Upjohn Co | 1-Lower alkyl-(1-adamantylmethyl)piperidines and process for their preparation |
| US4880696A (en) * | 1988-06-27 | 1989-11-14 | James River Ii, Inc. | Flexible packaging material containing an antioxidant |
| US5055328A (en) * | 1989-06-16 | 1991-10-08 | Viskase Corporation | Differentially cross-linked multilayer film |
| US5414049A (en) * | 1993-06-01 | 1995-05-09 | Howmedica Inc. | Non-oxidizing polymeric medical implant |
| ATE196994T1 (de) * | 1995-08-11 | 2000-11-15 | Smith & Nephew | Klebstoffe |
| US5879400A (en) | 1996-02-13 | 1999-03-09 | Massachusetts Institute Of Technology | Melt-irradiated ultra high molecular weight polyethylene prosthetic devices |
| ES2243980T3 (es) | 1996-02-13 | 2005-12-01 | Massachusetts Institute Of Technology | Dispositivos de protesis de polietileno de ultra alto peso molecular tratados por fusion y radiacion. |
| US5753182A (en) * | 1996-02-14 | 1998-05-19 | Biomet, Inc. | Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components |
| US6228900B1 (en) * | 1996-07-09 | 2001-05-08 | The Orthopaedic Hospital And University Of Southern California | Crosslinking of polyethylene for low wear using radiation and thermal treatments |
| US5827904A (en) | 1996-09-27 | 1998-10-27 | Hahn; David | Medical implant composition |
| US6017975A (en) * | 1996-10-02 | 2000-01-25 | Saum; Kenneth Ashley | Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance |
| FR2762428B1 (fr) | 1997-04-16 | 1999-06-11 | Schlumberger Ind Sa | Dispositif de visualisation d'un message sur un distributeur de carburant |
| JP4315261B2 (ja) * | 1998-02-25 | 2009-08-19 | ナカシマメディカル株式会社 | 人工関節用摺動部材および製造方法 |
| US6692679B1 (en) * | 1998-06-10 | 2004-02-17 | Depuy Orthopaedics, Inc. | Cross-linked molded plastic bearings |
| EP0995449A1 (de) * | 1998-10-21 | 2000-04-26 | Sulzer Orthopädie AG | UHMW-Polyethylen für Implantate |
| SE9900519D0 (sv) * | 1999-02-17 | 1999-02-17 | Lars Lidgren | A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof |
| US6620198B2 (en) * | 1999-10-07 | 2003-09-16 | Exactech, Inc. | Composite bearing inserts for total knee joints |
| ATE418933T1 (de) * | 2000-04-27 | 2009-01-15 | Orthopaedic Hospital | Oxidationsbeständige und abriebfeste polyethylene fur menschlichen gelenkersatz und verfahren zu deren herstellung |
| EP1330347B1 (de) | 2000-09-29 | 2006-08-16 | Depuy Orthopaedics, Inc. | Behandlung eines bestrahlten vorformlings eines prothetischen lagerelementes aus polyethylen mit einem überkritischen fluid |
| US6818172B2 (en) * | 2000-09-29 | 2004-11-16 | Depuy Products, Inc. | Oriented, cross-linked UHMWPE molding for orthopaedic applications |
| JP3548169B2 (ja) * | 2001-12-11 | 2004-07-28 | 住友ゴム工業株式会社 | 空気入りタイヤ |
| WO2004064618A2 (en) * | 2003-01-16 | 2004-08-05 | Massachusetts General Hospital | Methods for making oxidation resistant polymeric material |
| JP2004348118A (ja) | 2003-04-30 | 2004-12-09 | Toshiba Corp | フォトマスク及びそれを用いた露光方法、データ発生方法 |
| AT412969B (de) * | 2003-05-19 | 2005-09-26 | Klaus Dr Lederer | Vernetztes, ultra-hochmolekulares polyethylen (uhmw-pe) |
| ES2279930T3 (es) | 2003-10-14 | 2007-09-01 | Saab Ab | Procedimiento de formacion de una estructura compuesta. |
| EP1750614B1 (de) * | 2004-05-11 | 2017-09-27 | The General Hospital Corporation | Verfahren zur herstellung von oxidationsbeständigem polymermaterial |
| JP4913370B2 (ja) * | 2005-06-28 | 2012-04-11 | 株式会社アクトメント | 医療材料及びその製造方法 |
| ATE449618T1 (de) * | 2005-08-18 | 2009-12-15 | Zimmer Gmbh | Ultrahochmolekulare polyethylen-artikel und verfahren zur herstellung von ultrahochmolekularen polyethylen-artikeln |
| EP2456283B1 (de) | 2007-01-25 | 2015-12-16 | The General Hospital Corporation | Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial |
| AU2008222967B2 (en) * | 2007-03-02 | 2012-12-13 | Cambridge Polymer Group, Inc. | Cross-linking of antioxidant-containing polymers |
| US8641959B2 (en) * | 2007-07-27 | 2014-02-04 | Biomet Manufacturing, Llc | Antioxidant doping of crosslinked polymers to form non-eluting bearing components |
| US8872847B2 (en) | 2008-08-28 | 2014-10-28 | Google Inc. | Architectures and methods for creating and representing time-dependent imagery |
| WO2010096771A2 (en) * | 2009-02-20 | 2010-08-26 | The General Hospital Corporation Dba | High temperature melting |
| US9702220B2 (en) | 2012-02-21 | 2017-07-11 | Onesubsea Ip Uk Limited | Well tree hub and interface for retrievable processing modules |
-
2008
- 2008-01-25 EP EP11007297.2A patent/EP2456283B1/de not_active Not-in-force
- 2008-01-25 ES ES08728244T patent/ES2385317T3/es active Active
- 2008-01-25 US US12/522,728 patent/US8293811B2/en active Active
- 2008-01-25 AT AT08728244T patent/ATE555636T1/de active
- 2008-01-25 CA CA2674955A patent/CA2674955C/en not_active Expired - Fee Related
- 2008-01-25 EP EP08728244A patent/EP2110002B1/de not_active Not-in-force
- 2008-01-25 AU AU2008207807A patent/AU2008207807B2/en not_active Ceased
- 2008-01-25 EP EP12150677A patent/EP2464195A1/de not_active Withdrawn
- 2008-01-25 EP EP15200276.2A patent/EP3037442A1/de not_active Withdrawn
- 2008-01-25 JP JP2009547433A patent/JP5535650B2/ja not_active Expired - Fee Related
- 2008-01-25 WO PCT/US2008/051982 patent/WO2008092047A1/en not_active Ceased
-
2012
- 2012-07-31 US US13/562,867 patent/US8569395B2/en not_active Expired - Fee Related
-
2013
- 2013-09-25 US US14/036,586 patent/US9433705B2/en not_active Expired - Fee Related
-
2016
- 2016-06-24 US US15/191,857 patent/US9968709B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2464195A1 (de) | 2012-06-13 |
| CA2674955A1 (en) | 2008-07-31 |
| EP2110002A4 (de) | 2010-03-03 |
| US8569395B2 (en) | 2013-10-29 |
| US20140097559A1 (en) | 2014-04-10 |
| JP5535650B2 (ja) | 2014-07-02 |
| AU2008207807A1 (en) | 2008-07-31 |
| WO2008092047A1 (en) | 2008-07-31 |
| ES2385317T3 (es) | 2012-07-23 |
| EP3037442A1 (de) | 2016-06-29 |
| US20170049934A1 (en) | 2017-02-23 |
| EP2456283B1 (de) | 2015-12-16 |
| US9433705B2 (en) | 2016-09-06 |
| CA2674955C (en) | 2015-05-26 |
| EP2110002A1 (de) | 2009-10-21 |
| US9968709B2 (en) | 2018-05-15 |
| JP2010516517A (ja) | 2010-05-20 |
| US8293811B2 (en) | 2012-10-23 |
| EP2456283A1 (de) | 2012-05-23 |
| US20120292816A1 (en) | 2012-11-22 |
| EP2110002B1 (de) | 2012-04-25 |
| US20100190882A1 (en) | 2010-07-29 |
| AU2008207807B2 (en) | 2013-05-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE555636T1 (de) | Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial | |
| EP2085419A4 (de) | Verfahren zur herstellung von modifiziertem polymer, nach dem verfahren erhaltenes modifiziertes polymer und kautschukzusammensetzung damit | |
| WO2011076971A3 (es) | Artículo de peek poroso como implante | |
| WO2011110894A3 (en) | A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition | |
| EP1596755A4 (de) | Verfahren zur herstellung von oxidationsbeständigem polymermaterial | |
| DE60314865D1 (de) | Verfahren zur herstellung von modifiziertem polymer, danach erhaltenes modifiziertes polymer und kautschukzusammensetzung | |
| SG11201802892SA (en) | Hair strengthening composition and method for strengthening hair | |
| ATE547131T1 (de) | Verfahren zur herstellung von biomaterialien mit variabler steifheit | |
| ATE529475T1 (de) | Verfahren zur herstellung von polyethylen mit ultrahohem molekulargewicht | |
| DE602006020056D1 (de) | Dimercaptanterminierte polythioetherpolymere und verfahren zu ihrer herstellung und verwendung | |
| MY160836A (en) | Modified resin systems for liquid resin infusion applications & process methods related thereto | |
| HUE064687T2 (hu) | Konjugált dién alapú polimer, elágazást biztosító anyag, eljárás konjugált dién alapú polimer elõállítására, olajjal hígított konjugált dién alapú polimer, gumikészítmény és gumiabroncs | |
| HK1207557A1 (en) | Method and system for treating biological tissue | |
| EP3674330A4 (de) | Verfahren zur herstellung von modifiziertem konjugiertem dienbasiertem polymer | |
| ATE447593T1 (de) | Niedrigviskose uretdiongruppenhaltige polyadditionsverbindungen, verfahren zur herstellung und verwendung | |
| EP3763755C0 (de) | Erdölharz, hydriertes erdölharz und verfahren zur herstellung von hydriertem erdölharz | |
| EP3802688A4 (de) | Ethylenpolymermgemisch, verfahren zur herstellung davon und formartikel mit verwendung davon | |
| ATE545749T1 (de) | Oberflächenbelag mit eigenschaften zur ableitung der statischen elektrizität und verfahren zu dessen herstellung | |
| EP4074748C0 (de) | Aromatischer polyether, aromatische polyetherzusammensetzung, folie und verfahren zur herstellung von aromatischem polyether | |
| EP1972648A4 (de) | Aromatisches etherpolymer, herstellungsverfahren dafür und polymerzusammensetzung | |
| EP3584298A4 (de) | Polierzusammensetzung, verfahren zur herstellung davon und polierverfahren mit verwendung der polierzusammensetzung | |
| ATE512238T1 (de) | Materialsystem und verfahren zur dessen herstellung | |
| EP3604368A4 (de) | Härtbare zusammensetzung, verfahren zur herstellung davon und artikel mit verwendung davon | |
| EP3773770A4 (de) | Zusammensetzungen und verfahren zur herstellung und verwendung von nichtimmunogenen, schnell glühenden, mikroporösen, geglühten partikelhydrogelen | |
| MX2010003228A (es) | Ajuste de tiempo de curacion para articulo de caucho. |