ATE56729T1 - Protein mit zellwachstumsstimulierender wirkung, dessen zusammensetzung und verfahren zu seiner herstellung. - Google Patents

Protein mit zellwachstumsstimulierender wirkung, dessen zusammensetzung und verfahren zu seiner herstellung.

Info

Publication number: ATE56729T1
Authority: AT; Austria
Prior art keywords: molecular weight; protein; cell growth; growth stimulating; sub
Prior art date: 1983-06-30

Application number

AT84101573T

Other languages

English (en)

Inventor

Setsuro Fujii

Nobumoto Chikazawa

Teruo Arima

Masakazu Fukushima

Original Assignee

Sanwa Kagaku Kenkyusho Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-30

Filing date

1984-02-16

Publication date

1990-10-15

1984-02-16 Application filed by Sanwa Kagaku Kenkyusho Co filed Critical Sanwa Kagaku Kenkyusho Co

1990-10-15 Application granted granted Critical

1990-10-15 Publication of ATE56729T1 publication Critical patent/ATE56729T1/de

Links

102000004169 proteins and genes Human genes 0.000 title abstract 3
108090000623 proteins and genes Proteins 0.000 title abstract 3
230000010261 cell growth Effects 0.000 title abstract 2
230000004936 stimulating effect Effects 0.000 title abstract 2
230000002378 acidificating effect Effects 0.000 abstract 2
235000001014 amino acid Nutrition 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
235000018102 proteins Nutrition 0.000 abstract 2
241000283690 Bos taurus Species 0.000 abstract 1
241000283073 Equus caballus Species 0.000 abstract 1
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
102000036675 Myoglobin Human genes 0.000 abstract 1
108010062374 Myoglobin Proteins 0.000 abstract 1
108010011356 Nucleoside phosphotransferase Proteins 0.000 abstract 1
229930003270 Vitamin B Natural products 0.000 abstract 1
206010052428 Wound Diseases 0.000 abstract 1
208000027418 Wounds and injury Diseases 0.000 abstract 1
235000003704 aspartic acid Nutrition 0.000 abstract 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000011088 calibration curve Methods 0.000 abstract 1
235000013922 glutamic acid Nutrition 0.000 abstract 1
239000004220 glutamic acid Substances 0.000 abstract 1
238000004128 high performance liquid chromatography Methods 0.000 abstract 1
239000003550 marker Substances 0.000 abstract 1
230000007935 neutral effect Effects 0.000 abstract 1
230000001737 promoting effect Effects 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
235000019156 vitamin B Nutrition 0.000 abstract 1
239000011720 vitamin B Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/255—Salmonella (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/335—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S435/842—Clostridium
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- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/843—Corynebacterium
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/879—Salmonella
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- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/88—Serratia
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/882—Staphylococcus
- Y10S435/884—Staphylococcus epidermidis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Epidemiology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Inorganic Chemistry (AREA)
General Engineering & Computer Science (AREA)
Dermatology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT84101573T 1983-06-30 1984-02-16 Protein mit zellwachstumsstimulierender wirkung, dessen zusammensetzung und verfahren zu seiner herstellung. ATE56729T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP58119863A JPS6028999A (ja)	1983-06-30	1983-06-30	細胞増殖促進作用を有するたんぱく質、その組成物と製造方法
EP84101573A EP0134385B1 (de)	1983-06-30	1984-02-16	Protein mit Zellwachstumsstimulierender Wirkung, dessen Zusammensetzung und Verfahren zu seiner Herstellung

Publications (1)

Publication Number	Publication Date
ATE56729T1 true ATE56729T1 (de)	1990-10-15

Family

ID=14772132

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT84101573T ATE56729T1 (de)	1983-06-30	1984-02-16	Protein mit zellwachstumsstimulierender wirkung, dessen zusammensetzung und verfahren zu seiner herstellung.

Country Status (7)

Country	Link
US (1)	US4604234A (de)
EP (1)	EP0134385B1 (de)
JP (1)	JPS6028999A (de)
KR (1)	KR850000524A (de)
AT (1)	ATE56729T1 (de)
CA (1)	CA1224435A (de)
DE (1)	DE3483227D1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3346953A1 (de) *	1983-12-24	1985-08-14	Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg	Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung
FR2565985B1 (fr) *	1984-06-19	1987-09-25	Rhone Poulenc Sante	Nouvelles substances biologiquement actives obtenues a partir de la caseine bovine, leur procede de preparation et les compositions qui les contiennent
US4746729A (en) *	1986-07-30	1988-05-24	Kuettner Klaus E	Cartilage-derived leukocyte elastase-inhibitor
SE8604587D0 (sv) *	1986-10-28	1986-10-28	Pharmacia Ab	Lekemedelssats for sarlekningsstimulering samt sett att anvenda och tillverka satsen
US5019559A (en) *	1986-11-14	1991-05-28	President And Fellows Of Harvard College	Wound healing using PDGF and IGF-II
US4861757A (en) *	1986-11-14	1989-08-29	Institute Of Molecular Biology	Wound healing and bone regeneration using PDGF and IGF-I
GB8713169D0 (en) *	1987-06-05	1987-07-08	Peters T J	Uptake of iron by body
WO1988004180A1 (en) *	1986-12-11	1988-06-16	National Research Development Corporation	Improvements in or relating to the use of epidermal growth factor
JPH03503117A (ja) *	1988-02-12	1991-07-18	ハイテク　レセプター　アーベー	免疫グロブリン結合性物質そのサブフラグメント、それらの製造方法、試薬キットおよび免疫グロブリン結合性物質
US5256644A (en) *	1988-05-20	1993-10-26	Institute Of Molecular Biology, Inc.	Wound healing using IGF-II and TGF
US4983581A (en) *	1988-05-20	1991-01-08	Institute Of Molecular Biology, Inc.	Wound healing composition of IGF-I and TGF-β
US5006509A (en) *	1988-06-24	1991-04-09	Harald Waago	Use of human growth hormone in treating topical ulcers
US5034375A (en) *	1988-08-10	1991-07-23	Institute Of Molecular Biology, Inc.	Process of wound healing using PDGF and EGF
US5175147A (en) *	1988-08-19	1992-12-29	Takeda Chemical Industries, Ltd	Acid-resistant fgf composition and method of treating ulcerating diseases of the gastrointestinal tract
US5032575A (en) *	1988-10-12	1991-07-16	Eye Research Institute Of Retina Foundation, Inc.	Method for enhancing healing of corneal endothelial wounds
US5051443A (en) *	1988-10-12	1991-09-24	Eye Research Institute Of Retina Foundation, Inc.	Method for enhancing healing of corneal endothelial wounds
US5036046A (en) *	1988-10-12	1991-07-30	Eye Research Institute Of Retina Foundation, Inc.	Method for enhancing healing of corneal endothelial wounds
FR2647784B1 (fr) *	1989-06-06	1991-10-04	Grimberg Georges	Association de vitamine a a dose physiologique et de differents principes actifs ayant une activite therapeutique
US5206023A (en) *	1991-01-31	1993-04-27	Robert F. Shaw	Method and compositions for the treatment and repair of defects or lesions in cartilage
US5149691A (en) *	1991-03-12	1992-09-22	Creative Biomolecules, Inc.	Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
US5270300A (en) *	1991-09-06	1993-12-14	Robert Francis Shaw	Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
US5618544A (en) *	1992-08-12	1997-04-08	Bays-Brown Dermatologics, Inc.	Method of decreasing cutaneous senescence
EP0624642B1 (de) *	1993-05-12	1999-01-20	Indian Council For Medical Research	Neues thrombolytisches Agens, Verfahren zu seiner Herstellung und seines Gebrauches für die Herstellung eines thrombenauflösenden Arzneimittels
EP0661293A3 (de) *	1993-12-29	1999-05-19	Sanwa Kagaku Kenkyusho Co., Ltd.	Protein mit Zellwachstumsstimulierender und Makrophage chemotaktischer Wirkung, Verfahren zur Herstellung und Verwendung
GB9401689D0 (en) *	1994-01-28	1994-03-23	Univ Manchester	Diagnosis and treatment of endocarditis
US6541447B1 (en)	1999-09-01	2003-04-01	B & M Healthcare Technologies, Inc.	Wound healing composition and method for use thereof
CA2554534C (en)	2004-02-04	2013-01-08	Merck & Co., Inc.	Process for large scale production of plasmid dna by e. coli fermentation
US7897800B2 (en)	2006-02-03	2011-03-01	Jr Chem, Llc	Chemical compositions and methods of making them
US7687650B2 (en)	2006-02-03	2010-03-30	Jr Chem, Llc	Chemical compositions and methods of making them
AU2006337161B2 (en)	2006-02-03	2012-06-07	Obagi Cosmeceuticals Llc	Anti-aging treatment using copper and zinc compositions
CL2007002615A1 (es) *	2006-09-08	2008-04-18	Wyeth Corp	Metodos para aislar o purificar un producto que comprende poner el producto enlazado en contacto con al menos una solucion de lavado que comprende arginina y luego eluir el producto; y dicho producto.
US7867522B2 (en)	2006-09-28	2011-01-11	Jr Chem, Llc	Method of wound/burn healing using copper-zinc compositions
US8273791B2 (en)	2008-01-04	2012-09-25	Jr Chem, Llc	Compositions, kits and regimens for the treatment of skin, especially décolletage
US20160184354A1 (en)	2009-01-23	2016-06-30	Jr Chem, Llc	Rosacea treatments and kits for performing them
US8952057B2 (en)	2011-01-11	2015-02-10	Jr Chem, Llc	Compositions for anorectal use and methods for treating anorectal disorders

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2944940A (en) *	1956-01-16	1960-07-12	Armour & Co	Adrenocorticotrophin and zinc composition
NL268104A (de) *	1961-08-10
SE393532B (sv) *	1974-05-02	1977-05-16	Draco Ab	Sett att framstella en farmaceutisk zinkberedning for astadkommande av en smaklig, fordragbar, peroral zinklosning innehallande ett zinkkomplex
FR2269962B1 (de) *	1974-05-06	1978-02-03	Anvar
JPS6019733B2 (ja) *	1977-06-10	1985-05-17	科研製薬株式会社	蛋白質性活性物質
JPS5424801A (en) *	1977-07-28	1979-02-24	Karupisu Shiyokuhin Kougiyou K	Novel antibiotics cc3603 and process for preparing same
US4287184A (en) *	1977-11-23	1981-09-01	The Massachusetts General Hospital	Process for healing wounds
AU517061B2 (en) *	1978-04-12	1981-07-09	Hoechst Aktiengesellschaft	Alpha-amylase inhibitor
JPS5767591A (en) *	1980-10-11	1982-04-24	Kaken Pharmaceut Co Ltd	Protein element substance and its preparation
US4436816A (en) *	1982-01-22	1984-03-13	Pitman-Moore, Inc.	Cell growth promoting material
JPS58222026A (ja) *	1982-06-18	1983-12-23	Masahiro Yoshimura	抗ガン性物質
US4444760A (en) *	1983-06-17	1984-04-24	Merck & Co., Inc.	Purification and characterization of a protein fibroblast growth factor

1983
- 1983-06-30 JP JP58119863A patent/JPS6028999A/ja active Pending
1984
- 1984-02-16 AT AT84101573T patent/ATE56729T1/de not_active IP Right Cessation
- 1984-02-16 EP EP84101573A patent/EP0134385B1/de not_active Expired - Lifetime
- 1984-02-16 DE DE8484101573T patent/DE3483227D1/de not_active Expired - Fee Related
- 1984-02-23 CA CA000448163A patent/CA1224435A/en not_active Expired
- 1984-02-28 US US06/584,335 patent/US4604234A/en not_active Expired - Fee Related
- 1984-04-13 KR KR1019840001951A patent/KR850000524A/ko not_active Ceased

Also Published As

Publication number	Publication date
EP0134385A2 (de)	1985-03-20
CA1224435A (en)	1987-07-21
DE3483227D1 (de)	1990-10-25
EP0134385A3 (en)	1987-09-09
JPS6028999A (ja)	1985-02-14
US4604234A (en)	1986-08-05
KR850000524A (ko)	1985-02-27
EP0134385B1 (de)	1990-09-19

Legal Events

Date	Code	Title	Description
1991-03-15	UEP	Publication of translation of european patent specification
1998-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE56729T1 (de)	1990-10-15	Protein mit zellwachstumsstimulierender wirkung, dessen zusammensetzung und verfahren zu seiner herstellung.
KR880701288A (ko)	1988-07-26	M-csf의 제법
DE3584460D1 (de)	1991-11-28	Verfahren zur erhoehung der ausbeute von heterologen proteinen, produziert durch zuechtung von rekombinanten bakterien.
IL100240A0 (en)	1992-09-06	Bile acid derivatives,process for their preparation and use of these compounds as pharmaceuticals
IS2070B (is)	2005-12-15	Stöðugar interferónlyfjablöndur á vökvaformi
IL112585A (en)	2000-08-31	N-terminally chemically modified G-CSF and analogs process for their preparation and pharmaceutical compositions containing them
ATE25525T1 (de)	1987-03-15	N-glycosylierte carbonsaeureamid-derivate, verfahren zu ihrer herstellung sowie ihre verwendung zur beeinflussung der koerpereigenen abwehr.
ATE135712T1 (de)	1996-04-15	Polypeptid, dessen verfahren zur herstellung und dieses enthaltende pharmazeutische zusammensetzung und deren benutzung
US4514387A (en)	1985-04-30	Chemokinesins and chemotaxins of leukocytes and inflamed tissues
PT87658A (pt)	1988-07-01	Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet loesung enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin
ATE61068T1 (de)	1991-03-15	Verfahren zur herstellung eines dem menschlichen gamma-interferon aehnlichen polypeptids.
DK0386752T3 (da)	1994-12-05	Polypeptid og fremstilling heraf
LTIP610A (en)	1994-12-27	Inhibitors of cells proliferation, pharmaceutical composition and method for preparation of compounds
KR870004139A (ko)	1987-05-07	인체 λ-인터페론의 생물학적 활성 유도체를 제조하는 방법
ATE160588T1 (de)	1997-12-15	Aus bakteriellen proteinen bestehender extrakt, verfahren zur dessen herstellung und diesen extrakt enthaltende pharmazeutische zusammensetzung
ATE71110T1 (de)	1992-01-15	Verfahren zur reinigung eines proteins.
DE3687995D1 (de)	1993-04-22	Verfahren zur reinigung von interferon und so hergestellte zusammensetzung.
MA20303A1 (fr)	1985-07-01	Composition nutritive contenant de l'acide alpha-cetoisocaproique, de la leucine et des acides amines essentiels et non essentiels.
JPS57193494A (en)	1982-11-27	Method of purifying or concentrating biologically active protein and drug therefor
DE69232259D1 (de)	2002-01-17	Verfahren zur Herstellung von Interleukin-6 Zusammensetzungen
ATE44750T1 (de)	1989-08-15	Verfahren zur herstellung eines antihaemophiliefaktor-konzentrats.
KR850005456A (ko)	1985-08-26	고농도 단백질의 제조방법
Deshmukh et al.	1971	In vitro formation of crosslinks in mature rat skin collagen in the absence of N-terminal peptides
ES8706815A1 (es)	1987-07-16	Procedimiento de preparar bebidas alcoholicas que tiene un alto contenido de proteinas
Suzuki	1990	Structure and function of egg-associated peptides of sea urchins