ATE86868T1 - Verfahren zur reinigung von interferon und so hergestellte zusammensetzung. - Google Patents

Verfahren zur reinigung von interferon und so hergestellte zusammensetzung.

Info

Publication number: ATE86868T1
Authority: AT; Austria
Prior art keywords: interferon; composition; results; human immune; purification
Prior art date: 1985-04-25

Application number

AT86302960T

Other languages

English (en)

Inventor

Tsutomu Arakawa

Original Assignee

Amgen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-25

Filing date

1986-04-18

Publication date

1993-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24921509&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE86868(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-04-18 Application filed by Amgen Inc filed Critical Amgen Inc

1993-04-15 Application granted granted Critical

1993-04-15 Publication of ATE86868T1 publication Critical patent/ATE86868T1/de

Links

108010050904 Interferons Proteins 0.000 title abstract 3
102000014150 Interferons Human genes 0.000 title abstract 3
229940079322 interferon Drugs 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
238000000746 purification Methods 0.000 title 1
101000599940 Homo sapiens Interferon gamma Proteins 0.000 abstract 2
USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 abstract 1
239000005695 Ammonium acetate Substances 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
229940043376 ammonium acetate Drugs 0.000 abstract 1
235000019257 ammonium acetate Nutrition 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000004202 carbamide Substances 0.000 abstract 1
239000003398 denaturant Substances 0.000 abstract 1
238000000502 dialysis Methods 0.000 abstract 1
238000010790 dilution Methods 0.000 abstract 1
239000012895 dilution Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000007935 neutral effect Effects 0.000 abstract 1
239000012264 purified product Substances 0.000 abstract 1
239000000243 solution Substances 0.000 abstract 1
238000001228 spectrum Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/142—Interferon

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT86302960T 1985-04-25 1986-04-18 Verfahren zur reinigung von interferon und so hergestellte zusammensetzung. ATE86868T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/727,147 US4873312A (en)	1985-04-25	1985-04-25	Method for purifying interferon and composition of matter produced thereby
EP86302960A EP0199568B1 (de)	1985-04-25	1986-04-18	Verfahren zur Reinigung von Interferon und so hergestellte Zusammensetzung

Publications (1)

Publication Number	Publication Date
ATE86868T1 true ATE86868T1 (de)	1993-04-15

Family

ID=24921509

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86302960T ATE86868T1 (de)	1985-04-25	1986-04-18	Verfahren zur reinigung von interferon und so hergestellte zusammensetzung.

Country Status (8)

Country	Link
US (1)	US4873312A (de)
EP (1)	EP0199568B1 (de)
JP (1)	JPH0733397B2 (de)
AT (1)	ATE86868T1 (de)
CA (1)	CA1263842A (de)
DE (1)	DE3687995T2 (de)
IL (1)	IL78455A (de)
WO (1)	WO1986006385A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1339757C (en)	1987-04-16	1998-03-17	Robert F. Halenbeck	Production of purified biologically active, bacterially produced recombinant human csf-1
US4929700A (en) *	1987-04-16	1990-05-29	Cetus Corporation	Production of purified, biologically active, bacterially produced recombinant human CSF-1
US4931543A (en) *	1987-05-11	1990-06-05	Cetus Corporation	Process for recovering microbially produced interleukin-2
US5599690A (en) *	1988-02-01	1997-02-04	Amgen Inc.	Control of norleucine incorporation into recombinant proteins
US5391713A (en) *	1989-06-20	1995-02-21	Bionative Ab	Interferon purification process
DE3926103A1 (de) *	1989-08-08	1991-02-14	Hoechst Ag	Verfahren zur biokatalytischen korrekten kettenfaltung denaturierter rekombinanter fusionsproteine
DK580789D0 (da) *	1989-11-20	1989-11-20	Novo Nordisk As	Fremgangsmaade til oprensning af polypeptider
US5986070A (en) *	1990-04-06	1999-11-16	Amgen Inc.	Production of biologically active NGF proteins
IT1246296B (it) *	1990-07-25	1994-11-17	Sclavo Spa	Procedimento di estrzione e purificazione del gamma interferone umano ricombinante

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5821691A (ja) *	1981-07-29	1983-02-08	Mochida Pharmaceut Co Ltd	α−及びβ−インタ−フェロンの精製方法
AU561343B2 (en) *	1981-10-19	1987-05-07	Genentech Inc.	Human immune interferon by recombinant dna
US6936694B1 (en) *	1982-05-06	2005-08-30	Intermune, Inc.	Manufacture and expression of large structural genes
WO1984002129A1 (fr) *	1982-11-22	1984-06-07	Takeda Chemical Industries Ltd	Proteine de l'interferon immun humain et son procede de preparation
US4518526A (en) *	1982-12-22	1985-05-21	Genentech, Inc.	Purification and activity assurance of precipitated heterologous proteins
JPH06102034B2 (ja) *	1983-03-25	1994-12-14	セルテクリミテツド	タンパク質の生産方法
US4476049A (en) *	1983-09-20	1984-10-09	Hoffmann-La Roche Inc.	Method for the extraction of immune interferon
JPS6079000A (ja) *	1983-10-04	1985-05-04	Takeda Chem Ind Ltd	ヒトγ型インタ−フエロン単量体の製造法
US4855238A (en) *	1983-12-16	1989-08-08	Genentech, Inc.	Recombinant gamma interferons having enhanced stability and methods therefor

1985
- 1985-04-25 US US06/727,147 patent/US4873312A/en not_active Expired - Fee Related
1986
- 1986-04-04 CA CA000505897A patent/CA1263842A/en not_active Expired
- 1986-04-09 JP JP61502079A patent/JPH0733397B2/ja not_active Expired - Lifetime
- 1986-04-09 IL IL78455A patent/IL78455A/xx not_active IP Right Cessation
- 1986-04-09 WO PCT/US1986/000723 patent/WO1986006385A1/en not_active Ceased
- 1986-04-18 AT AT86302960T patent/ATE86868T1/de not_active IP Right Cessation
- 1986-04-18 DE DE8686302960T patent/DE3687995T2/de not_active Revoked
- 1986-04-18 EP EP86302960A patent/EP0199568B1/de not_active Revoked

Also Published As

Publication number	Publication date
CA1263842A (en)	1989-12-12
IL78455A (en)	1991-11-21
JPS62502540A (ja)	1987-10-01
WO1986006385A1 (en)	1986-11-06
IL78455A0 (en)	1986-08-31
EP0199568A2 (de)	1986-10-29
EP0199568B1 (de)	1993-03-17
DE3687995D1 (de)	1993-04-22
DE3687995T2 (de)	1993-06-24
EP0199568A3 (en)	1988-09-21
US4873312A (en)	1989-10-10
JPH0733397B2 (ja)	1995-04-12

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Legal Events

Date	Code	Title	Description
1993-10-15	UEP	Publication of translation of european patent specification
1996-08-15	RZN	Patent revoked