ATE62248T1 - Ein doxorubicinderivat, ein verfahren zu dessen herstellung, pharmazeutische zusammensetzungen und dessen verwendung fuer die herstellung von arzneimitteln. - Google Patents

Ein doxorubicinderivat, ein verfahren zu dessen herstellung, pharmazeutische zusammensetzungen und dessen verwendung fuer die herstellung von arzneimitteln.

Info

Publication number
ATE62248T1
ATE62248T1 AT88100677T AT88100677T ATE62248T1 AT E62248 T1 ATE62248 T1 AT E62248T1 AT 88100677 T AT88100677 T AT 88100677T AT 88100677 T AT88100677 T AT 88100677T AT E62248 T1 ATE62248 T1 AT E62248T1
Authority
AT
Austria
Prior art keywords
production
doxorubic
derivative
pharmaceutical compositions
medicinal products
Prior art date
Application number
AT88100677T
Other languages
English (en)
Inventor
Giuseppe Cassinelli
Teresa Bordoni
Sergio Merli
Giovanni Rivola
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Application granted granted Critical
Publication of ATE62248T1 publication Critical patent/ATE62248T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT88100677T 1987-01-22 1988-01-19 Ein doxorubicinderivat, ein verfahren zu dessen herstellung, pharmazeutische zusammensetzungen und dessen verwendung fuer die herstellung von arzneimitteln. ATE62248T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB878701381A GB8701381D0 (en) 1987-01-22 1987-01-22 Antitumor agent
EP88100677A EP0275966B1 (de) 1987-01-22 1988-01-19 Ein Doxorubicinderivat, ein Verfahren zu dessen Herstellung, pharmazeutische Zusammensetzungen und dessen Verwendung für die Herstellung von Arzneimitteln
HU883699A HU201972B (en) 1987-01-22 1988-07-15 Process for producing antitumour 4'-deoxy-13(s)-dihydro-4'-iododoxorubicin hydrochloride by stereoselective microbiological reduction of 4'-deoxy-4'-iododoxorubicin
CA000572117A CA1294911C (en) 1987-01-22 1988-07-15 Antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin

Publications (1)

Publication Number Publication Date
ATE62248T1 true ATE62248T1 (de) 1991-04-15

Family

ID=27167996

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88100677T ATE62248T1 (de) 1987-01-22 1988-01-19 Ein doxorubicinderivat, ein verfahren zu dessen herstellung, pharmazeutische zusammensetzungen und dessen verwendung fuer die herstellung von arzneimitteln.

Country Status (12)

Country Link
US (1) US4895933A (de)
EP (1) EP0275966B1 (de)
JP (1) JP2592479B2 (de)
CN (1) CN1039617A (de)
AT (1) ATE62248T1 (de)
CA (1) CA1294911C (de)
DE (1) DE3862196D1 (de)
ES (1) ES2036602T3 (de)
GB (1) GB8701381D0 (de)
GR (1) GR3001717T3 (de)
HU (1) HU201972B (de)
ZA (1) ZA884653B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU601857B2 (en) * 1988-06-30 1990-09-20 Pharmacia & Upjohn S.P.A. A new antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin
IL110289A (en) * 1993-08-06 1998-01-04 Policlinico San Matteo Istitut Pharmaceutical preparations containing 4-iodo-4-deoxydoxorubicin for the treatment of amyloidosis
IT1285777B1 (it) * 1996-10-07 1998-06-18 Indena Spa Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati
KR20100110378A (ko) 2002-05-24 2010-10-12 안지오테크 인터내셔날 아게 의료용 임플란트를 피복하기 위한 조성물 및 방법
US20040146546A1 (en) 2002-09-26 2004-07-29 Angiotech Pharmaceuticals, Inc. Perivascular wraps
ATE457716T1 (de) 2002-12-30 2010-03-15 Angiotech Int Ag Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
EP3084445B1 (de) 2013-12-11 2020-10-28 University of Massachusetts Zusammensetzungen und verfahren zur behandlung einer krankheit mithilfe des salmonella-t3ss-effektorproteins (sipa)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE35993B1 (en) * 1971-01-20 1976-07-21 Rhone Poulenc Sa Process for the preparation of antibiotics 20,798 rp and 27,706 rp and the antibiotic 27,706 rp
US4427664A (en) * 1981-05-29 1984-01-24 The United States Of America As Represented By The Department Of Health And Human Services 2'Halo derivatives of daunomycin, desmethoxy daunomycin, adriamycin and carminomycin
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides

Also Published As

Publication number Publication date
JPS63218694A (ja) 1988-09-12
ES2036602T3 (es) 1993-06-01
CA1294911C (en) 1992-01-28
DE3862196D1 (de) 1991-05-08
HU201972B (en) 1991-01-28
CN1039617A (zh) 1990-02-14
JP2592479B2 (ja) 1997-03-19
EP0275966A1 (de) 1988-07-27
US4895933A (en) 1990-01-23
GB8701381D0 (en) 1987-02-25
HUT50513A (en) 1990-02-28
ZA884653B (en) 1989-03-29
EP0275966B1 (de) 1991-04-03
GR3001717T3 (en) 1992-11-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee