PT87972A - Processo para a preparacao de4'-deoxi-13(s)-dihidro-4'-iododoxorubicina com actividade anti-tumor mediante reducao estereo-selectiva microbiana de 4'-deoxi-4'-iododoxorubicina - Google Patents
Processo para a preparacao de4'-deoxi-13(s)-dihidro-4'-iododoxorubicina com actividade anti-tumor mediante reducao estereo-selectiva microbiana de 4'-deoxi-4'-iododoxorubicinaInfo
- Publication number
- PT87972A PT87972A PT8797288A PT8797288A PT87972A PT 87972 A PT87972 A PT 87972A PT 8797288 A PT8797288 A PT 8797288A PT 8797288 A PT8797288 A PT 8797288A PT 87972 A PT87972 A PT 87972A
- Authority
- PT
- Portugal
- Prior art keywords
- deoxy
- doxorubicin
- iodo
- obtd
- redn
- Prior art date
Links
- 241000187081 Streptomyces peucetius Species 0.000 title abstract 3
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 title 4
- 229960004679 doxorubicin Drugs 0.000 title 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- WTLKTXIHIHFSGU-UHFFFAOYSA-N 2-nitrosoguanidine Chemical compound NC(N)=NN=O WTLKTXIHIHFSGU-UHFFFAOYSA-N 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT8797288A PT87972B (pt) | 1988-07-12 | 1988-07-12 | Processo para a preparacao de4'-deoxi-13(s)-dihidro-4'-iododoxorubicina com actividade anti-tumor mediante reducao estereo-selectiva microbiana de 4'-deoxi-4'-iododoxorubicina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT8797288A PT87972B (pt) | 1988-07-12 | 1988-07-12 | Processo para a preparacao de4'-deoxi-13(s)-dihidro-4'-iododoxorubicina com actividade anti-tumor mediante reducao estereo-selectiva microbiana de 4'-deoxi-4'-iododoxorubicina |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87972A true PT87972A (pt) | 1991-03-20 |
| PT87972B PT87972B (pt) | 1995-03-01 |
Family
ID=20084273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT8797288A PT87972B (pt) | 1988-07-12 | 1988-07-12 | Processo para a preparacao de4'-deoxi-13(s)-dihidro-4'-iododoxorubicina com actividade anti-tumor mediante reducao estereo-selectiva microbiana de 4'-deoxi-4'-iododoxorubicina |
Country Status (1)
| Country | Link |
|---|---|
| PT (1) | PT87972B (pt) |
-
1988
- 1988-07-12 PT PT8797288A patent/PT87972B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT87972B (pt) | 1995-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU1170095A (en) | Locking device for drawers and the like | |
| EP0870771A4 (en) | SUGAR COMPOUNDS | |
| AU2974489A (en) | 3'-deamino-4'-deoxy-4'-amino anthracyclines | |
| IL116559A (en) | Chimeric protein consisting of a bacterial toxin and a myelin basic protein sequence | |
| IL117656A (en) | Pharmaceutical compositions comprising a supported saccharide for the treatment of travellers' diarrhea caused by E.coli LT enterotoxin | |
| DE3061789D1 (en) | Process for the preparation of pure 4.4-dihydroxydiphenyl alkanes or cycloalkanes | |
| GB8701381D0 (en) | Antitumor agent | |
| CA2092045A1 (en) | Erythromycin derivatives, preparation and use thereof | |
| IL72214A0 (en) | Anthracycline derivatives,a microbiological process for their preparation and their use as cytostatics | |
| EP0488718A3 (en) | Immunostimulant agent containing interleukin-2 and 5'-deoxy-5-fluorouridine | |
| NO934293L (no) | Fremgangsmåte og streptomycesstamme for fremstilling av antiparastiske forbindelser | |
| PT87972A (pt) | Processo para a preparacao de4'-deoxi-13(s)-dihidro-4'-iododoxorubicina com actividade anti-tumor mediante reducao estereo-selectiva microbiana de 4'-deoxi-4'-iododoxorubicina | |
| EP0254484A3 (en) | 6-amino anthracyclines, process for their preparation and use thereof | |
| MY105727A (en) | Muramyl dipeptide derivatives. | |
| CA2037431A1 (en) | Transposon consisting of a fragment of the r plasmid pcxm82b | |
| MY103552A (en) | Saccharide derivatives | |
| CA2107110A1 (en) | Novel Immunosuppressant Agent from Streptomyces Braegensis | |
| ZA90835B (en) | 4'-epi-4'-amino anthracyclines | |
| CA2004206A1 (en) | Method for preparing pertussis toxin toxoid | |
| IE811453L (en) | Cephalosporin sulfoxides | |
| AU7734687A (en) | Novel substituted (4.2.0.)bicyclooctane derivatives with valuable therapeutic properties | |
| ES8706816A1 (es) | Un procedimiento para la preparacion de un nuevo compuesto denominado sustancia n. 51262 por cultivo de un microorganismo del genero streptomyces | |
| ES480904A1 (es) | Un procedimiento para la produccion del antibiotico mycopla-necin. | |
| DE3360601D1 (en) | Macrolide antibiotics from streptomyces | |
| GB2137204B (en) | Improvements in or relating to macrolideantibiotics |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940818 |
|
| PC3A | Transfer or assignment |
Free format text: 961212 PHARMACIA & UPJOHN S.P.A. IT |
|
| TE3A | Change of address (patent) | ||
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20040229 |