ATE66602T1 - Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen. - Google Patents
Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen.Info
- Publication number
- ATE66602T1 ATE66602T1 AT88402734T AT88402734T ATE66602T1 AT E66602 T1 ATE66602 T1 AT E66602T1 AT 88402734 T AT88402734 T AT 88402734T AT 88402734 T AT88402734 T AT 88402734T AT E66602 T1 ATE66602 T1 AT E66602T1
- Authority
- AT
- Austria
- Prior art keywords
- drug
- stimulate
- incorporate
- ability
- host cells
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 4
- -1 NITROPHENYL GROUPS Chemical group 0.000 title 1
- 125000006501 nitrophenyl group Chemical group 0.000 abstract 2
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8715127A FR2622445B1 (fr) | 1987-10-30 | 1987-10-30 | Application de groupes nitrophenyles a la stimulation des capacites d'incorporation d'un medicament dans les cellules sensibles de l'hote |
| EP88402734A EP0314580B1 (de) | 1987-10-30 | 1988-10-28 | Verwendung von Nitrophenylgruppen zur Stimulierung der Inkorporationsfähigkeit eines Arzneimittels in die empfindlichen Wirtszellen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE66602T1 true ATE66602T1 (de) | 1991-09-15 |
Family
ID=9356379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88402734T ATE66602T1 (de) | 1987-10-30 | 1988-10-28 | Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0314580B1 (de) |
| JP (1) | JPH02501933A (de) |
| AT (1) | ATE66602T1 (de) |
| DE (1) | DE3864490D1 (de) |
| DK (1) | DK328189A (de) |
| ES (1) | ES2037862T3 (de) |
| FR (1) | FR2622445B1 (de) |
| GR (1) | GR3002665T3 (de) |
| WO (1) | WO1989003680A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991015200A2 (en) * | 1990-04-03 | 1991-10-17 | Radopath Limited | Use of trinitrobenzenes or carminic acid in the treatment of cancer or viral diseases |
-
1987
- 1987-10-30 FR FR8715127A patent/FR2622445B1/fr not_active Expired - Lifetime
-
1988
- 1988-10-28 ES ES198888402734T patent/ES2037862T3/es not_active Expired - Lifetime
- 1988-10-28 WO PCT/FR1988/000534 patent/WO1989003680A1/fr not_active Ceased
- 1988-10-28 EP EP88402734A patent/EP0314580B1/de not_active Expired - Lifetime
- 1988-10-28 AT AT88402734T patent/ATE66602T1/de not_active IP Right Cessation
- 1988-10-28 JP JP63509063A patent/JPH02501933A/ja active Pending
- 1988-10-28 DE DE8888402734T patent/DE3864490D1/de not_active Expired - Lifetime
-
1989
- 1989-06-30 DK DK328189A patent/DK328189A/da not_active Application Discontinuation
-
1991
- 1991-09-06 GR GR91401273T patent/GR3002665T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK328189D0 (da) | 1989-06-30 |
| FR2622445A1 (fr) | 1989-05-05 |
| EP0314580B1 (de) | 1991-08-28 |
| EP0314580A1 (de) | 1989-05-03 |
| DK328189A (da) | 1989-06-30 |
| WO1989003680A1 (fr) | 1989-05-05 |
| ES2037862T3 (es) | 1993-07-01 |
| FR2622445B1 (fr) | 1990-07-27 |
| GR3002665T3 (en) | 1993-01-25 |
| DE3864490D1 (de) | 1991-10-02 |
| JPH02501933A (ja) | 1990-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |