ATE66602T1 - Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen. - Google Patents

Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen.

Info

Publication number
ATE66602T1
ATE66602T1 AT88402734T AT88402734T ATE66602T1 AT E66602 T1 ATE66602 T1 AT E66602T1 AT 88402734 T AT88402734 T AT 88402734T AT 88402734 T AT88402734 T AT 88402734T AT E66602 T1 ATE66602 T1 AT E66602T1
Authority
AT
Austria
Prior art keywords
drug
stimulate
incorporate
ability
host cells
Prior art date
Application number
AT88402734T
Other languages
English (en)
Inventor
Eustrate-Stratis Avrameas
Panayota Matsiota-Bernard
Therese Ternynck
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE66602T1 publication Critical patent/ATE66602T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT88402734T 1987-10-30 1988-10-28 Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen. ATE66602T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8715127A FR2622445B1 (fr) 1987-10-30 1987-10-30 Application de groupes nitrophenyles a la stimulation des capacites d'incorporation d'un medicament dans les cellules sensibles de l'hote
EP88402734A EP0314580B1 (de) 1987-10-30 1988-10-28 Verwendung von Nitrophenylgruppen zur Stimulierung der Inkorporationsfähigkeit eines Arzneimittels in die empfindlichen Wirtszellen

Publications (1)

Publication Number Publication Date
ATE66602T1 true ATE66602T1 (de) 1991-09-15

Family

ID=9356379

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88402734T ATE66602T1 (de) 1987-10-30 1988-10-28 Verwendung von nitrophenylgruppen zur stimulierung der inkorporationsfaehigkeit eines arzneimittels in die empfindlichen wirtszellen.

Country Status (9)

Country Link
EP (1) EP0314580B1 (de)
JP (1) JPH02501933A (de)
AT (1) ATE66602T1 (de)
DE (1) DE3864490D1 (de)
DK (1) DK328189A (de)
ES (1) ES2037862T3 (de)
FR (1) FR2622445B1 (de)
GR (1) GR3002665T3 (de)
WO (1) WO1989003680A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06501449A (ja) * 1990-04-03 1994-02-17 ラドパス リミテッド 癌またはウイル性疾患の治療におけるトリニトロベンゼン類またはカルミン酸の使用

Also Published As

Publication number Publication date
EP0314580A1 (de) 1989-05-03
DK328189D0 (da) 1989-06-30
GR3002665T3 (en) 1993-01-25
ES2037862T3 (es) 1993-07-01
FR2622445A1 (fr) 1989-05-05
JPH02501933A (ja) 1990-06-28
WO1989003680A1 (fr) 1989-05-05
FR2622445B1 (fr) 1990-07-27
DE3864490D1 (de) 1991-10-02
EP0314580B1 (de) 1991-08-28
DK328189A (da) 1989-06-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee