ATE99669T1 - N-2,3-butadienyl-tri-aminoalkanderivate. - Google Patents

N-2,3-butadienyl-tri-aminoalkanderivate.

Info

Publication number
ATE99669T1
ATE99669T1 AT89114354T AT89114354T ATE99669T1 AT E99669 T1 ATE99669 T1 AT E99669T1 AT 89114354 T AT89114354 T AT 89114354T AT 89114354 T AT89114354 T AT 89114354T AT E99669 T1 ATE99669 T1 AT E99669T1
Authority
AT
Austria
Prior art keywords
butadienyl
tri
aminoalkaline
derivatives
polyamines
Prior art date
Application number
AT89114354T
Other languages
English (en)
Inventor
Philippe Bey
David M Stemerick
Michael L Edwards
Alan J Bitonti
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE99669T1 publication Critical patent/ATE99669T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/21—Monoamines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
AT89114354T 1988-08-04 1989-08-03 N-2,3-butadienyl-tri-aminoalkanderivate. ATE99669T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/228,620 US4935449A (en) 1988-08-04 1988-08-04 N-2,3-butadienyl tri- and tetraaminoalkane derivatives
EP89114354A EP0353752B1 (de) 1988-08-04 1989-08-03 N-2,3-Butadienyl-tri-aminoalkanderivate

Publications (1)

Publication Number Publication Date
ATE99669T1 true ATE99669T1 (de) 1994-01-15

Family

ID=22857945

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89114354T ATE99669T1 (de) 1988-08-04 1989-08-03 N-2,3-butadienyl-tri-aminoalkanderivate.

Country Status (19)

Country Link
US (1) US4935449A (de)
EP (1) EP0353752B1 (de)
JP (1) JP2722255B2 (de)
KR (1) KR0144155B1 (de)
CN (1) CN1039800A (de)
AT (1) ATE99669T1 (de)
AU (1) AU617502B2 (de)
CA (1) CA1321603C (de)
DE (1) DE68912020T2 (de)
DK (1) DK381189A (de)
ES (1) ES2061826T3 (de)
FI (1) FI893681L (de)
HU (1) HU207833B (de)
IL (1) IL91184A0 (de)
NO (1) NO172043C (de)
NZ (1) NZ230155A (de)
PH (1) PH27214A (de)
PT (1) PT91365A (de)
ZA (1) ZA895840B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9111794D0 (en) * 1991-05-31 1991-07-24 Robins David J Antifungal compounds
ES2119371T3 (es) * 1993-12-27 1998-10-01 Novartis Ag Aminocompuestos insaturados para usar como un agente anticancerigeno y antiprotozoico.
US5677350A (en) * 1995-06-07 1997-10-14 Wisconsin Alumni Research Foundation Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
HK1040993B (en) 1999-04-30 2006-11-10 Cellgate, Inc. Polyamines and their use in therapy
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
BR0010700A (pt) * 1999-04-30 2002-02-13 Slil Biomedical Corp Conjugados análogos de poliamina e conjugados de quinona como terapias para cânceres e doenças na próstata
AU2002235126A1 (en) * 2000-11-08 2002-05-21 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
US7045550B2 (en) * 2001-08-07 2006-05-16 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
US7273888B2 (en) * 2001-11-16 2007-09-25 Als Therapy Development Foundation, Inc. Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
JP2005511734A (ja) * 2001-12-07 2005-04-28 スリル バイオメディカル コーポレイション 癌治療用のシクロアルキル置換ポリアミンおよびそれらの合成方法
KR20040091014A (ko) * 2002-02-07 2004-10-27 위스콘신 얼럼나이 리서어치 화운데이션 항암 요법과 병행해서 사용하기 위한 폴리아민 화합물 및조성물
EP3971178A1 (de) 2012-03-07 2022-03-23 The McLean Hospital Corporation Aminochinolinderivate und verwendungen davon
CN102924390B (zh) * 2012-09-07 2014-12-31 苏州康润医药有限公司 1,5-二氮杂环辛烷-1-甲酸叔丁酯的合成方法
WO2021108632A1 (en) 2019-11-25 2021-06-03 The General Hospital Corporation Methods and compositions for enzymatic polymerization of n3' -> p5' phosphoramidate dna

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551550A (en) * 1983-12-06 1985-11-05 Merrell Dow Pharmaceuticals Inc. N-2,3-Butadienyl-1,4-butanediamine derivatives
DE3462686D1 (de) * 1983-12-06 1987-04-23 Merrell Dow Pharma N-2,3-butadienyl-1,4-butanediamine derivatives
ZA88600B (en) * 1987-02-03 1988-07-28 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase

Also Published As

Publication number Publication date
NO893135L (no) 1990-02-05
FI893681A7 (fi) 1990-02-05
NO893135D0 (no) 1989-08-03
PH27214A (en) 1993-05-04
ES2061826T3 (es) 1994-12-16
HU207833B (en) 1993-06-28
NO172043B (no) 1993-02-22
KR900003105A (ko) 1990-03-23
IL91184A0 (en) 1990-03-19
KR0144155B1 (ko) 1998-07-15
AU3927189A (en) 1990-02-08
FI893681A0 (fi) 1989-08-03
DK381189A (da) 1990-02-05
DE68912020D1 (de) 1994-02-17
ZA895840B (en) 1990-04-25
CN1039800A (zh) 1990-02-21
DK381189D0 (da) 1989-08-03
CA1321603C (en) 1993-08-24
PT91365A (pt) 1990-03-08
JPH0283357A (ja) 1990-03-23
AU617502B2 (en) 1991-11-28
HUT58037A (en) 1992-01-28
JP2722255B2 (ja) 1998-03-04
EP0353752B1 (de) 1994-01-05
EP0353752A1 (de) 1990-02-07
DE68912020T2 (de) 1994-04-28
US4935449A (en) 1990-06-19
FI893681L (fi) 1990-02-05
NO172043C (no) 1993-06-02
NZ230155A (en) 1991-08-27

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties