ATE66919T1 - Thiophen-derivate. - Google Patents
Thiophen-derivate.Info
- Publication number
- ATE66919T1 ATE66919T1 AT88310085T AT88310085T ATE66919T1 AT E66919 T1 ATE66919 T1 AT E66919T1 AT 88310085 T AT88310085 T AT 88310085T AT 88310085 T AT88310085 T AT 88310085T AT E66919 T1 ATE66919 T1 AT E66919T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- hydrogen
- optionally protected
- optionally
- alkenyl
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000000304 alkynyl group Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000002825 nitriles Chemical class 0.000 abstract 2
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Electrophonic Musical Instruments (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878725260A GB8725260D0 (en) | 1987-10-28 | 1987-10-28 | Organic compounds |
| EP88310085A EP0314464B1 (de) | 1987-10-28 | 1988-10-27 | Thiophen-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE66919T1 true ATE66919T1 (de) | 1991-09-15 |
Family
ID=10626046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88310085T ATE66919T1 (de) | 1987-10-28 | 1988-10-27 | Thiophen-derivate. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4886885A (de) |
| EP (1) | EP0314464B1 (de) |
| JP (1) | JPH01230572A (de) |
| AT (1) | ATE66919T1 (de) |
| DE (1) | DE3864660D1 (de) |
| ES (1) | ES2031606T3 (de) |
| GB (1) | GB8725260D0 (de) |
| GR (1) | GR3002958T3 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03204875A (ja) * | 1989-10-03 | 1991-09-06 | Wakamoto Pharmaceut Co Ltd | テトラゾール酢酸誘導体、及び該誘導体を有効成分とするアルドースレダクターゼ阻害剤 |
| JP2671059B2 (ja) * | 1990-11-30 | 1997-10-29 | 富士レビオ株式会社 | ナフトエ酸誘導体 |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US6162857A (en) | 1997-07-21 | 2000-12-19 | Eastman Chemical Company | Process for making polyester/platelet particle compositions displaying improved dispersion |
| US6734207B2 (en) * | 2001-04-20 | 2004-05-11 | Parker Hughes Institute | Cytotoxic compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2424742C3 (de) * | 1974-05-21 | 1982-04-22 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Thiophenderivate Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| EP0123543B1 (de) * | 1983-04-21 | 1988-02-03 | Merck Frosst Canada Inc. | Leukotrienantagonisten, deren Herstellung und Verwendung sowie diese enthaltende Zusammensetzungen |
| GB8320943D0 (en) * | 1983-08-03 | 1983-09-07 | Lilly Industries Ltd | Organic compounds |
| GB8432144D0 (en) * | 1984-12-20 | 1985-01-30 | Lilly Industries Ltd | Organic compounds |
| GB8502258D0 (en) * | 1985-01-30 | 1985-02-27 | Lilly Industries Ltd | Organic compounds |
| US4663332A (en) * | 1985-10-10 | 1987-05-05 | Hoffman-La Roche Inc. | 5-substituted N-alkylated tetrazoles |
| GB8530222D0 (en) * | 1985-12-07 | 1986-01-15 | Lilly Industries Ltd | Organic compounds |
| US4785004A (en) * | 1985-12-23 | 1988-11-15 | Ciba-Geigy Corporation | Aromatic thioethers |
| US4752613A (en) * | 1987-08-03 | 1988-06-21 | E. R. Squibb & Sons, Inc. | Sulphonamidothienylcarboxylic acid compounds |
-
1987
- 1987-10-28 GB GB878725260A patent/GB8725260D0/en active Pending
-
1988
- 1988-10-26 US US07/262,754 patent/US4886885A/en not_active Expired - Fee Related
- 1988-10-27 EP EP88310085A patent/EP0314464B1/de not_active Expired - Lifetime
- 1988-10-27 ES ES198888310085T patent/ES2031606T3/es not_active Expired - Lifetime
- 1988-10-27 JP JP63271911A patent/JPH01230572A/ja active Pending
- 1988-10-27 DE DE8888310085T patent/DE3864660D1/de not_active Expired - Fee Related
- 1988-10-27 AT AT88310085T patent/ATE66919T1/de not_active IP Right Cessation
-
1991
- 1991-10-22 GR GR91401589T patent/GR3002958T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01230572A (ja) | 1989-09-14 |
| US4886885A (en) | 1989-12-12 |
| EP0314464A1 (de) | 1989-05-03 |
| EP0314464B1 (de) | 1991-09-04 |
| GB8725260D0 (en) | 1987-12-02 |
| ES2031606T3 (es) | 1992-12-16 |
| DE3864660D1 (en) | 1991-10-10 |
| GR3002958T3 (en) | 1993-01-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE19575041I2 (de) | Substituierte Acyl-Derivate von 1, 2, 3, 4-Tetrahydro-6, 7-dimethoxy-3-isoquinolin-Carbonsaeure | |
| DK0412404T3 (da) | Thiazolderivater, fremgangsmåder til fremstilling deraf og farmaceutiske præparater omfattende derivaterne | |
| PT90805A (pt) | Processo para a preparacao de 1-indolilalquil-4-(piridinil substituido)-piperazinas e de composicoes farmaceuticas que as contem | |
| DK249089A (da) | Benzamid-forbindelser, der er nyttige som protease-inhibitorer | |
| FI941649A0 (fi) | Retroviirusproteaasi-inhibiittoreina käytettäviä syklisiä ureoita ja analogeja | |
| DK0418071T3 (da) | Nye N-aryl- og N-heteroarylamid- og urinstofderivater som inhibitorer for acyl-coenzym A: cholesterol-acyltransferase | |
| DE3871916D1 (de) | Thiazolidindione als hypoglykaemische und antiatherosklerotische mittel. | |
| KR890003720A (ko) | 벤조티아졸 및 그를 유효성분으로 함유하는 항류머티스제 | |
| DE68929330D1 (de) | Zwischenprodukte für die Herstellung von Derivaten der 4-Oxochinolin-3-carbonsäure | |
| AR003137A1 (es) | Una composicion farmaceutica para tratar la leucemia | |
| DE3879258D1 (de) | Praeparat gegen ulcus. | |
| ATE66919T1 (de) | Thiophen-derivate. | |
| LV11689A (lv) | 4-Ú(2-benzotiazolil)metilamino¾-alfa-Ú(3,4-difluorfenoksi)metil¾-1-piperidinetanols | |
| DE3684457D1 (de) | Organische verbindungen und ihre pharmazeutische verwendung. | |
| NO885313D0 (no) | Nye forbindelser. | |
| ES2059348T3 (es) | Composicion farmaceutica para el tratamiento de cataratas. | |
| DE68905406D1 (de) | Chinolin-verbindung. | |
| SE7809127L (sv) | Allenaminer | |
| DK0826663T3 (da) | Alkynylaminosyrederivater og deres anvendelse som farmaceutiske forbindelser |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |