ATE68491T1 - Aminomethyl-, n-phenyl-substituierte oxooxazolidin derivate nuetzlich als antibakterielle mittel. - Google Patents

Aminomethyl-, n-phenyl-substituierte oxooxazolidin derivate nuetzlich als antibakterielle mittel.

Info

Publication number: ATE68491T1
Authority: AT; Austria
Prior art keywords: phenyl; oxooxazolidine; aminomethyl; substituted; antibacterial agents
Prior art date: 1984-12-05

Application number

AT85115243T

Other languages

English (en)

Inventor

Walter Adelman Gregory

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-05

Filing date

1985-11-30

Publication date

1991-11-15

1985-11-30 Application filed by Du Pont filed Critical Du Pont

1991-11-15 Application granted granted Critical

1991-11-15 Publication of ATE68491T1 publication Critical patent/ATE68491T1/de

Links

-1 AMINOMETHYL Chemical class 0.000 title 2
239000003242 anti bacterial agent Substances 0.000 title 1
DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
BXOVBIFUCKLXHK-UHFFFAOYSA-N 2-[2-(aminomethyl)phenyl]-1,3-oxazolidin-4-one Chemical class NCC1=CC=CC=C1C1OCC(=O)N1 BXOVBIFUCKLXHK-UHFFFAOYSA-N 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT85115243T 1984-12-05 1985-11-30 Aminomethyl-, n-phenyl-substituierte oxooxazolidin derivate nuetzlich als antibakterielle mittel. ATE68491T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US67674584A	1984-12-05	1984-12-05
EP85115243A EP0184170B1 (de)	1984-12-05	1985-11-30	Aminomethyl-, N-Phenyl-substituierte Oxooxazolidin Derivate nützlich als antibakterielle Mittel

Publications (1)

Publication Number	Publication Date
ATE68491T1 true ATE68491T1 (de)	1991-11-15

Family

ID=24715801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85115243T ATE68491T1 (de)	1984-12-05	1985-11-30	Aminomethyl-, n-phenyl-substituierte oxooxazolidin derivate nuetzlich als antibakterielle mittel.

Country Status (17)

Country	Link
EP (1)	EP0184170B1 (de)
JP (1)	JPS61134379A (de)
AT (1)	ATE68491T1 (de)
AU (1)	AU611627B2 (de)
CA (1)	CA1260948A (de)
DE (1)	DE3584427D1 (de)
DK (1)	DK169103B1 (de)
ES (1)	ES8705404A1 (de)
FI (1)	FI82453C (de)
GR (1)	GR852919B (de)
HU (1)	HU194195B (de)
IE (1)	IE58325B1 (de)
NO (1)	NO164540C (de)
NZ (1)	NZ214437A (de)
PT (1)	PT81610B (de)
SU (1)	SU1528317A3 (de)
ZA (1)	ZA859329B (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES533097A0 (es) *	1983-06-07	1985-08-01	Du Pont	Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US5036092A (en) *	1987-10-09	1991-07-30	Du Pont Merck Pharmaceutical	Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) *	1987-10-09	1989-01-31	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5036093A (en) *	1987-10-09	1991-07-30	Du Pont Merck Pharmaceutical	Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) *	1987-10-09	1990-05-01	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4985429A (en) *	1987-10-09	1991-01-15	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) *	1987-10-09	1990-10-23	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5039690A (en) *	1987-10-09	1991-08-13	Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) *	1987-10-09	1991-07-16	Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) *	1987-10-16	1993-07-27	The Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US4942183A (en) *	1987-10-16	1990-07-17	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
ATE95176T1 (de) *	1987-10-21	1993-10-15	Du Pont Merck Pharma	Aminomethyl-oxo-oxazolidinyl-ethenylbenzenderivate, nuetzlich als antibakterielles mittel.
US4977173A (en) *	1987-10-21	1990-12-11	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents
US4948801A (en) *	1988-07-29	1990-08-14	E. I. Du Pont De Nemours And Company	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5182403A (en) *	1988-09-15	1993-01-26	The Upjohn Company	Substituted 3(5'indazolyl) oxazolidin-2-ones
ES2157934T3 (es) *	1988-09-15	2001-09-01	Upjohn Co	Fenil-5-beta-amidometiloxazolidin-2-onas sustituidas con nitrogeno en la posicion 3.
US5225565A (en) *	1988-09-15	1993-07-06	The Upjohn Company	Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
US5231188A (en) *	1989-11-17	1993-07-27	The Upjohn Company	Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
EP0610265B1 (de) *	1991-11-01	1996-12-27	PHARMACIA & UPJOHN COMPANY	Substituierte aryl- und heteroaryl-phenyloxazolidinone
DE69316240T2 (de) *	1992-12-08	1998-05-20	Upjohn Co	Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel
US5688792A (en) *	1994-08-16	1997-11-18	Pharmacia & Upjohn Company	Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en) *	1993-09-09	2003-04-30	Upjohn Co	Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9601666D0 (en) *	1996-01-27	1996-03-27	Zeneca Ltd	Chemical compounds
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
GB9609919D0 (en) *	1996-05-11	1996-07-17	Zeneca Ltd	Chemical compounds
US6255304B1 (en)	1997-05-30	2001-07-03	Pharmacia & Upjohn Company	Oxazolidinone antibacterial agents having a thiocarbonyl functionality
FI19992555A7 (fi)	1997-05-30	1999-11-30	Upjohn Co	Antibakteerisia oksatosolidinoniaineita, joilla on tiokarbonyylifunktionaalisuus
GB9717804D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9717807D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9725244D0 (en)	1997-11-29	1998-01-28	Zeneca Ltd	Chemical compounds
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
CA2318969A1 (en) *	1998-01-23	1999-07-29	Mikhail F. Gordeev	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
US6518285B2 (en) *	1999-12-21	2003-02-11	Ortho Mcneil Pharmaceutical, Inc.	Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
GB0009803D0 (en)	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
US6410728B1 (en) *	2000-08-31	2002-06-25	Abbott Laboratories	Oxazolidinone chemotherapeutic agents
CA2464109A1 (en)	2001-10-18	2003-12-24	Michigan State University	Process for the preparation of oxazolidinones and method of use thereof
WO2003072576A2 (en) *	2002-02-28	2003-09-04	Astrazeneca Ab	Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
NZ535592A (en)	2002-02-28	2006-07-28	Astrazeneca Ab	3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
AU2012258618B2 (en) *	2011-05-26	2017-05-25	Sunovion Pharmaceuticals Inc.	Metabotropic glutamate receptors 5 modulators and methods of use thereof
JP6286536B2 (ja) *	2013-11-08	2018-02-28	リーファーマリミテッドＬｅｅＰｈａｒｍａＬｉｍｉｔｅｄ	新規オキサゾリジノン抗菌化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1222708A (en) *	1968-10-22	1971-02-17	Delalande Sa	Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
USRE29607E (en)	1969-03-18	1978-04-11	Delalande S. A.	Derivatives of 5-hydroxymethyl-3-substituted-2-oxazolidinones, process of preparation thereof and therapeutic application
LU80081A1 (fr)	1977-08-26	1979-05-15	Delalande Sa	Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
US4128654A (en)	1978-02-10	1978-12-05	E. I. Du Pont De Nemours And Company	5-Halomethyl-3-phenyl-2-oxazolidinones
US4340606A (en) *	1980-10-23	1982-07-20	E. I. Du Pont De Nemours And Company	3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr)	1981-02-25	1982-08-27	Delalande Sa	Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
AU560666B2 (en) *	1981-12-04	1987-04-16	E.I. Du Pont De Nemours And Company	P(2-oxo oxazolidinyl)benzene sulphonamides
US4461773A (en)	1982-09-15	1984-07-24	E. I. Dupont De Nemours And Company	P-Oxooxazolidinylbenzene compounds as antibacterial agents
ES533097A0 (es) *	1983-06-07	1985-08-01	Du Pont	Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.

1985
- 1985-11-28 CA CA000496421A patent/CA1260948A/en not_active Expired
- 1985-11-30 DE DE8585115243T patent/DE3584427D1/de not_active Expired - Lifetime
- 1985-11-30 EP EP85115243A patent/EP0184170B1/de not_active Expired - Lifetime
- 1985-11-30 AT AT85115243T patent/ATE68491T1/de active
- 1985-12-04 PT PT81610A patent/PT81610B/pt not_active IP Right Cessation
- 1985-12-04 NO NO854883A patent/NO164540C/no unknown
- 1985-12-04 NZ NZ214437A patent/NZ214437A/xx unknown
- 1985-12-04 DK DK561885A patent/DK169103B1/da not_active IP Right Cessation
- 1985-12-04 GR GR852919A patent/GR852919B/el unknown
- 1985-12-04 SU SU853988501A patent/SU1528317A3/ru active
- 1985-12-04 HU HU854642A patent/HU194195B/hu not_active IP Right Cessation
- 1985-12-04 FI FI854804A patent/FI82453C/fi not_active IP Right Cessation
- 1985-12-04 ES ES549579A patent/ES8705404A1/es not_active Expired
- 1985-12-04 IE IE304785A patent/IE58325B1/en not_active IP Right Cessation
- 1985-12-04 JP JP60271719A patent/JPS61134379A/ja active Pending
- 1985-12-05 ZA ZA859329A patent/ZA859329B/xx unknown
- 1985-12-05 AU AU50816/85A patent/AU611627B2/en not_active Expired

Also Published As

Publication number	Publication date
NO854883L (no)	1986-06-06
EP0184170A2 (de)	1986-06-11
HUT39436A (en)	1986-09-29
NO164540B (no)	1990-07-09
GR852919B (de)	1986-04-07
FI82453B (fi)	1990-11-30
FI854804A7 (fi)	1986-06-06
AU5081685A (en)	1987-06-11
NZ214437A (en)	1989-01-06
SU1528317A3 (ru)	1989-12-07
DE3584427D1 (de)	1991-11-21
PT81610A (en)	1986-01-01
CA1260948A (en)	1989-09-26
ES549579A0 (es)	1987-05-01
IE58325B1 (en)	1993-09-08
DK561885D0 (da)	1985-12-04
FI82453C (fi)	1991-03-11
DK169103B1 (da)	1994-08-15
ES8705404A1 (es)	1987-05-01
HU194195B (en)	1988-01-28
DK561885A (da)	1986-06-06
FI854804A0 (fi)	1985-12-04
IE853047L (en)	1986-06-05
NO164540C (no)	1990-10-17
ZA859329B (en)	1987-08-26
EP0184170B1 (de)	1991-10-16
PT81610B (pt)	1988-04-21
AU611627B2 (en)	1991-06-20
JPS61134379A (ja)	1986-06-21
EP0184170A3 (en)	1987-09-02

Publication	Publication Date	Title
DE3584427D1 (de)	1991-11-21	Aminomethyl-, n-phenyl-substituierte oxooxazolidin derivate nuetzlich als antibakterielle mittel.
DE3869310D1 (de)	1992-04-23	Aminomethyl-oxo-oxazolidinyl-aroylbenzen-derivate, nuetzlich als antibakterielles mittel.
DE3884563D1 (de)	1993-11-04	Aminomethyl-oxo-oxazolidinyl-ethenylbenzen-derivate, nuetzlich als antibakterielles mittel.
MY104096A (en)	1993-11-30	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68917163D1 (de)	1994-09-08	Antibakterielle Mittel.
IT8026698A0 (it)	1980-12-17	Nastro a strati di inchiosyro colorato, trasferibili per effetto termico.
FI902710A0 (fi)	1990-05-31	Pyranylcyanoguanidinderivat.
ATE47853T1 (de)	1989-11-15	5,6-difluornaphtyridine und 5,6,8trifluorchinoline verwendbar als antibakterielle mittel.
ATE59842T1 (de)	1991-01-15	Indanamin-derivate als antiarrhythmische mittel.
IT1212143B (it)	1989-11-08	Composizione ad attivita'tricogena.
ES2053579T3 (es)	1994-08-01	Nuevas fenilureas.
ATE54151T1 (de)	1990-07-15	Erythromycylamin-derivate.
ATE176477T1 (de)	1999-02-15	Neue phospholipidderivate
IT1167609B (it)	1987-05-13	Nuovi composti chimici ad attivita' antiflogistica, antisettica, detergente
ATE70841T1 (de)	1992-01-15	2-(1-oxo-1-imino-1-thiacycloalkyl)-thiopenemderivate.
IT8420075A0 (it)	1984-03-16	Composti ad attivita'antibatterica.
FI860287L (fi)	1986-07-24	3-(piperidinyl)- och 3-(pyrrolidinyl) -1h-indazoler, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
ATE68490T1 (de)	1991-11-15	Als antibakterielle mittel verwendbare aminomethyloxooxazolidinyl-benzol-derivate.
SU1610823A1 (ru)	2000-05-10	S-трет-бутилтиуронийбромид, обладающий антиишемической активностью
ATE101148T1 (de)	1994-02-15	Alpha,alpha-disubstituierte aromaten und heteroaromaten als wahrnehmungssteigernde mittel.