ES549579A0 - Un procedimiento para la preparacion de derivadas de aminometil-oxooxazolidinilbenceno, utliles como agentes antibacterianos. - Google Patents

Un procedimiento para la preparacion de derivadas de aminometil-oxooxazolidinilbenceno, utliles como agentes antibacterianos.

Info

Publication number: ES549579A0
Authority: ES; Spain
Prior art keywords: derivatives; oxooxazolidinilbenceno; aminometil; procedure; useful
Prior art date: 1984-12-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES549579A

Other languages

English (en)

Other versions

ES8705404A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

EIDP Inc

Original Assignee

EI Du Pont de Nemours and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-05

Filing date

1985-12-04

Publication date

1987-05-01

1985-12-04 Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co

1987-05-01 Publication of ES549579A0 publication Critical patent/ES549579A0/es

1987-05-01 Publication of ES8705404A1 publication Critical patent/ES8705404A1/es

Status Expired legal-status Critical Current

Links

239000003242 anti bacterial agent Substances 0.000 title 1
DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
BXOVBIFUCKLXHK-UHFFFAOYSA-N 2-[2-(aminomethyl)phenyl]-1,3-oxazolidin-4-one Chemical class NCC1=CC=CC=C1C1OCC(=O)N1 BXOVBIFUCKLXHK-UHFFFAOYSA-N 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

ES549579A 1984-12-05 1985-12-04 Un procedimiento para la preparacion de derivadas de aminometil-oxooxazolidinilbenceno, utliles como agentes antibacterianos. Expired ES8705404A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US67674584A	1984-12-05	1984-12-05

Publications (2)

Publication Number	Publication Date
ES549579A0 true ES549579A0 (es)	1987-05-01
ES8705404A1 ES8705404A1 (es)	1987-05-01

Family

ID=24715801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES549579A Expired ES8705404A1 (es)	1984-12-05	1985-12-04	Un procedimiento para la preparacion de derivadas de aminometil-oxooxazolidinilbenceno, utliles como agentes antibacterianos.

Country Status (17)

Country	Link
EP (1)	EP0184170B1 (es)
JP (1)	JPS61134379A (es)
AT (1)	ATE68491T1 (es)
AU (1)	AU611627B2 (es)
CA (1)	CA1260948A (es)
DE (1)	DE3584427D1 (es)
DK (1)	DK169103B1 (es)
ES (1)	ES8705404A1 (es)
FI (1)	FI82453C (es)
GR (1)	GR852919B (es)
HU (1)	HU194195B (es)
IE (1)	IE58325B1 (es)
NO (1)	NO164540C (es)
NZ (1)	NZ214437A (es)
PT (1)	PT81610B (es)
SU (1)	SU1528317A3 (es)
ZA (1)	ZA859329B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES8506659A1 (es) *	1983-06-07	1985-08-01	Du Pont	Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US4801600A (en) *	1987-10-09	1989-01-31	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5036092A (en) *	1987-10-09	1991-07-30	Du Pont Merck Pharmaceutical	Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US4985429A (en) *	1987-10-09	1991-01-15	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4921869A (en) *	1987-10-09	1990-05-01	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) *	1987-10-09	1990-10-23	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US5039690A (en) *	1987-10-09	1991-08-13	Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US5036093A (en) *	1987-10-09	1991-07-30	Du Pont Merck Pharmaceutical	Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) *	1987-10-09	1991-07-16	Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4942183A (en) *	1987-10-16	1990-07-17	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
CA1320730C (en) *	1987-10-16	1993-07-27	The Du Pont Merck Pharmaceutical Company	Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
ES2059467T3 (es) *	1987-10-21	1994-11-16	Du Pont Merck Pharma	Derivados de aminometil-oxooxazolidinil-etenilbenceno utiles como agentes antibacterianos.
US4977173A (en) *	1987-10-21	1990-12-11	E. I. Du Pont De Nemours And Company	Aminomethyl oxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents
US4948801A (en) *	1988-07-29	1990-08-14	E. I. Du Pont De Nemours And Company	Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
ATE112773T1 (de) *	1988-09-15	1994-10-15	Upjohn Co	5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(nitrogen- substituierte)phenyl-5-beta-amidomethyloxazolid n-2-one.
US5182403A (en) *	1988-09-15	1993-01-26	The Upjohn Company	Substituted 3(5'indazolyl) oxazolidin-2-ones
US5225565A (en) *	1988-09-15	1993-07-06	The Upjohn Company	Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
US5231188A (en) *	1989-11-17	1993-07-27	The Upjohn Company	Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
AU667198B2 (en) *	1991-11-01	1996-03-14	Pharmacia & Upjohn Company	Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
JP3558088B2 (ja) *	1992-12-08	2004-08-25	ファルマシア・アンド・アップジョン・カンパニー	トロポン−置換のフェニルオキサゾリジノン抗菌剤
US5688792A (en) *	1994-08-16	1997-11-18	Pharmacia & Upjohn Company	Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en) *	1993-09-09	2003-04-30	Upjohn Co	Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9601666D0 (en) *	1996-01-27	1996-03-27	Zeneca Ltd	Chemical compounds
GB9702213D0 (en)	1996-02-24	1997-03-26	Zeneca Ltd	Chemical compounds
GB9609919D0 (en)	1996-05-11	1996-07-17	Zeneca Ltd	Chemical compounds
CN1138765C (zh) *	1997-05-30	2004-02-18	法玛西雅厄普约翰美国公司	带有硫代羰基功能基的噁唑烷酮抗菌剂
US6255304B1 (en)	1997-05-30	2001-07-03	Pharmacia & Upjohn Company	Oxazolidinone antibacterial agents having a thiocarbonyl functionality
GB9717804D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9717807D0 (en)	1997-08-22	1997-10-29	Zeneca Ltd	Chemical compounds
GB9725244D0 (en)	1997-11-29	1998-01-28	Zeneca Ltd	Chemical compounds
WO1999037630A1 (en) *	1998-01-23	1999-07-29	Versicor, Inc.	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
US6518285B2 (en) *	1999-12-21	2003-02-11	Ortho Mcneil Pharmaceutical, Inc.	Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
GB0009803D0 (en)	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
US6410728B1 (en) *	2000-08-31	2002-06-25	Abbott Laboratories	Oxazolidinone chemotherapeutic agents
JP2005519996A (ja)	2001-10-18	2005-07-07	ミシガンステイトユニバーシティー	オキサゾリジノン類の製造方法及びその使用方法
AU2003207340A1 (en)	2002-02-28	2003-09-09	Astrazeneca Ab	3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents
NZ535591A (en) *	2002-02-28	2006-07-28	Astrazeneca Ab	Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them
WO2012162635A1 (en) *	2011-05-26	2012-11-29	Sunovion Pharmaceuticals Inc.	Metabotropic glutamate receptors 5 modulators and methods of use thereof
US9573910B2 (en) *	2013-11-08	2017-02-21	Lee Pharma Limited	Oxazolidinone antibacterial compound

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1222708A (en) *	1968-10-22	1971-02-17	Delalande Sa	Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
USRE29607E (en)	1969-03-18	1978-04-11	Delalande S. A.	Derivatives of 5-hydroxymethyl-3-substituted-2-oxazolidinones, process of preparation thereof and therapeutic application
LU80081A1 (fr)	1977-08-26	1979-05-15	Delalande Sa	Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
US4128654A (en)	1978-02-10	1978-12-05	E. I. Du Pont De Nemours And Company	5-Halomethyl-3-phenyl-2-oxazolidinones
US4340606A (en) *	1980-10-23	1982-07-20	E. I. Du Pont De Nemours And Company	3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr) *	1981-02-25	1982-08-27	Delalande Sa	Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
ES8401951A1 (es) *	1981-12-04	1984-01-16	Du Pont	Un procedimiento para la preparacion de derivados de bencenosulfonamidas.
US4461773A (en)	1982-09-15	1984-07-24	E. I. Dupont De Nemours And Company	P-Oxooxazolidinylbenzene compounds as antibacterial agents
ES8506659A1 (es) *	1983-06-07	1985-08-01	Du Pont	Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.

1985
- 1985-11-28 CA CA000496421A patent/CA1260948A/en not_active Expired
- 1985-11-30 EP EP85115243A patent/EP0184170B1/en not_active Expired - Lifetime
- 1985-11-30 DE DE8585115243T patent/DE3584427D1/de not_active Expired - Lifetime
- 1985-11-30 AT AT85115243T patent/ATE68491T1/de active
- 1985-12-04 HU HU854642A patent/HU194195B/hu not_active IP Right Cessation
- 1985-12-04 NZ NZ214437A patent/NZ214437A/xx unknown
- 1985-12-04 JP JP60271719A patent/JPS61134379A/ja active Pending
- 1985-12-04 IE IE304785A patent/IE58325B1/en not_active IP Right Cessation
- 1985-12-04 SU SU853988501A patent/SU1528317A3/ru active
- 1985-12-04 NO NO854883A patent/NO164540C/no unknown
- 1985-12-04 PT PT81610A patent/PT81610B/pt not_active IP Right Cessation
- 1985-12-04 ES ES549579A patent/ES8705404A1/es not_active Expired
- 1985-12-04 FI FI854804A patent/FI82453C/fi not_active IP Right Cessation
- 1985-12-04 GR GR852919A patent/GR852919B/el unknown
- 1985-12-04 DK DK561885A patent/DK169103B1/da not_active IP Right Cessation
- 1985-12-05 ZA ZA859329A patent/ZA859329B/xx unknown
- 1985-12-05 AU AU50816/85A patent/AU611627B2/en not_active Expired

Also Published As

Publication number	Publication date
HU194195B (en)	1988-01-28
GR852919B (es)	1986-04-07
IE58325B1 (en)	1993-09-08
HUT39436A (en)	1986-09-29
NZ214437A (en)	1989-01-06
PT81610A (en)	1986-01-01
IE853047L (en)	1986-06-05
EP0184170B1 (en)	1991-10-16
NO164540C (no)	1990-10-17
FI82453C (fi)	1991-03-11
FI854804A7 (fi)	1986-06-06
ATE68491T1 (de)	1991-11-15
PT81610B (pt)	1988-04-21
FI854804A0 (fi)	1985-12-04
JPS61134379A (ja)	1986-06-21
NO854883L (no)	1986-06-06
EP0184170A2 (en)	1986-06-11
CA1260948A (en)	1989-09-26
DK169103B1 (da)	1994-08-15
AU5081685A (en)	1987-06-11
DK561885D0 (da)	1985-12-04
DE3584427D1 (de)	1991-11-21
EP0184170A3 (en)	1987-09-02
FI82453B (fi)	1990-11-30
NO164540B (no)	1990-07-09
DK561885A (da)	1986-06-06
ZA859329B (en)	1987-08-26
ES8705404A1 (es)	1987-05-01
AU611627B2 (en)	1991-06-20
SU1528317A3 (ru)	1989-12-07

Legal Events

Date	Code	Title	Description
1997-07-01	FD1A	Patent lapsed	Effective date: 19970519

Publication	Publication Date	Title
EP0184170A3 (en)	1987-09-02	Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
FI870113A0 (fi)	1987-01-13	Menetelmä uusien terapeuttisesti käyttökelpoisten 4,5,6-substioitujenN-(substituoitu-fenyyli)-2-pyrimidiiniamiinien valmistamiseksi
ES542320A0 (es)	1985-12-16	Un procedimiento para la preparacion de derivados de la 2 pirimidinil 1 piperazina
FI884755A0 (fi)	1988-10-14	Aminometyloxo-oxazolidinylaroyl -benzenderivat anvaendbara som antibakteriella aemnen.
HUT52075A (en)	1990-06-28	Process for producing pharmaceutical compositions comprising (aminomethyloxooxazolidinyl)-ethylene benzene derivatives as active ingredient and for producing the active ingredient
ES557151A0 (es)	1987-08-16	Un procedimiento para preparar laudanos
ES540637A0 (es)	1986-05-16	Un procedimiento de producir un compuesto de guanidina acti-vo como fungicida, de baja toxicidad.
PT87051A (pt)	1988-04-01	Process for preparing indane sulphonamide antiarrhythmic agents
IT1212143B (it)	1989-11-08	Composizione ad attivita'tricogena.
GB8707309D0 (en)	1987-04-29	Compounds
ES543419A0 (es)	1986-08-16	Un procedimiento para la preparacion de nuevos compuestos de sulfonil urea.
ES503143A0 (es)	1982-11-01	Procedimiento para la obtencion de benzoil-(tio)ureas susti-tuidas,de efecto pesticida
PT84498B (pt)	1989-11-10	Processo para a preparacao de novas fenil-ureias
ES538040A0 (es)	1985-11-01	Procedimiento para preparar compuesto de adicion apropiados como agentes dispersantes.
ES2055699T3 (es)	1994-09-01	Un procedimiento para la preparacion de nuevos derivados de eritromicilamina.
ES509168A0 (es)	1982-12-16	"procedimiento para la preparacion de derivados de fenoxi-aminopropanol substituidos" como divisional de la patente de invencion n 502.649 del 1 junio 1981.
PT82322B (pt)	1988-10-14	Processo para a preparacao de cicloalcanocarboxanilidas
ATE70841T1 (de)	1992-01-15	2-(1-oxo-1-imino-1-thiacycloalkyl)-thiopenemderivate.
ES530841A0 (es)	1985-05-16	Procedimiento para la obtencion de un nuevo derivado del acido tiolactico
AR217342A1 (es)	1980-03-14	Compuestos de 1,1-dioxido de acido 6-aminopenicilanico desprovistos de actividad terapeutica,utiles como intermediarios para la preparacion de un inhibidor de beta-lactamasa y un procedimiento para preparar el inhibidor de beta-lactamasa partiendo de dichos intermediarios
ES2175273T3 (es)	2002-11-16	Procedimiento para la preparacion de 5-(alcoximetil)-2,3-piridindicarboximidas.
ES2033772T3 (es)	1993-04-01	Un procedimiento para preparar n-metil-carbamato de 2-cloro-4(cianometil)tio)fenilo.
ES498238A0 (es)	1981-12-01	Procedimiento para la obtencion de acido n-(3-(1'-3''-oxa- pentametilenamino-etilidenamino)-2,4,6-triyodobenzoil)-b- amino-@-metil-propionico
AR220601A1 (es)	1980-11-14	Nuevo procedimiento para la fabricacion de la n-metil-n'-2,4-xilil-n-(n-2,4-xililformimidoil)formamidina
ES509169A0 (es)	1982-12-16	"un procedimiento para la preparacion de cicloalca 4,5 pirrolo 2,3-g-isoquinolinas" como divisional de la patente de invencion n 499.861 del 27 febrero 1981.