ATE68964T1 - Liposomen mit anthracyclinderivaten enthaltende mittel. - Google Patents

Liposomen mit anthracyclinderivaten enthaltende mittel.

Info

Publication number
ATE68964T1
ATE68964T1 AT88905137T AT88905137T ATE68964T1 AT E68964 T1 ATE68964 T1 AT E68964T1 AT 88905137 T AT88905137 T AT 88905137T AT 88905137 T AT88905137 T AT 88905137T AT E68964 T1 ATE68964 T1 AT E68964T1
Authority
AT
Austria
Prior art keywords
appropriations
containing liposomes
liposomes
improved
anthracyclin
Prior art date
Application number
AT88905137T
Other languages
English (en)
Inventor
Roman Perez-Soler
Waldemar Priebe
Gabriel Lopez-Berestein
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE68964T1 publication Critical patent/ATE68964T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT88905137T 1987-05-19 1988-05-18 Liposomen mit anthracyclinderivaten enthaltende mittel. ATE68964T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/051,890 US4863739A (en) 1987-05-19 1987-05-19 Liposome compositions of anthracycline derivatives
PCT/US1988/001723 WO1988009166A1 (en) 1987-05-19 1988-05-18 Liposome compositions of anthracycline derivatives
EP88905137A EP0358719B1 (de) 1987-05-19 1988-05-18 Liposomen mit anthracyclinderivaten enthaltende mittel

Publications (1)

Publication Number Publication Date
ATE68964T1 true ATE68964T1 (de) 1991-11-15

Family

ID=21973993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88905137T ATE68964T1 (de) 1987-05-19 1988-05-18 Liposomen mit anthracyclinderivaten enthaltende mittel.

Country Status (7)

Country Link
US (1) US4863739A (de)
EP (1) EP0358719B1 (de)
JP (1) JP2716178B2 (de)
AT (1) ATE68964T1 (de)
AU (1) AU609156B2 (de)
DE (1) DE3865966D1 (de)
WO (1) WO1988009166A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3641835A1 (de) * 1986-12-08 1988-06-16 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
US5811119A (en) * 1987-05-19 1998-09-22 Board Of Regents, The University Of Texas Formulation and use of carotenoids in treatment of cancer
US4950432A (en) * 1987-10-16 1990-08-21 Board Of Regents, The University Of Texas System Polyene microlide pre-liposomal powders
US4981690A (en) * 1987-10-27 1991-01-01 Board Of Regents, The University Of Texas System Liposome-incorporated mepartricin
JPH03502327A (ja) * 1988-01-19 1991-05-30 ボード・オブ・リージェンツ，ザ・ユニバーシティ・オブ・テキサス・システム ３’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5356633A (en) * 1989-10-20 1994-10-18 Liposome Technology, Inc. Method of treatment of inflamed tissues
WO1991009616A1 (en) * 1989-12-22 1991-07-11 Yale University Quinolone antibiotics encapsulated in lipid vesicles
DE4122744C2 (de) * 1990-08-06 1994-02-03 Nattermann A & Cie Wäßriges Liposomensystem und Verfahren zu seiner Herstellung
WO1994020114A1 (en) * 1993-03-12 1994-09-15 Board Of Regents, The University Of Texas System Anthracyclines with unusually high activity against cells resistant to doxorubicin and its analogs
US5834012A (en) * 1995-05-03 1998-11-10 Roman Perez-Soler Lipid complexed topoisomerase I inhibitors
US5902604A (en) * 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
US5858397A (en) * 1995-10-11 1999-01-12 University Of British Columbia Liposomal formulations of mitoxantrone
CA2368656A1 (en) * 2002-01-21 2003-07-21 Vasogen Ireland Limited Receptor-ligand pairing for anti-inflammatory response
US20050058698A1 (en) * 2002-01-21 2005-03-17 Nolan Yvonne Mairead Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease
AU2003284149A1 (en) * 2002-10-15 2004-05-04 The Government Of The United States, As Represented By The Secretary Of Health And Human Services Compositions and methods for inhibiting group b streptococcus-induced pulmonary hypertension in neonates
WO2006113679A2 (en) 2005-04-15 2006-10-26 Board Of Regents, The University Of Texas System Delivery of sirna by neutral lipid compositions
WO2009059449A1 (en) 2007-11-05 2009-05-14 Celsion Corporation Novel thermosensitive liposomes containing therapeutic agents
EP3989978B1 (de) 2019-06-28 2025-12-17 Board of Regents, The University of Texas System Herstellung eines präliposomalen annamycin-lyophilisats
WO2020264161A1 (en) 2019-06-28 2020-12-30 Donald Picker Method of reconstituting liposomal annamycin
AU2020386092A1 (en) * 2019-11-21 2022-06-16 Board Of Regents, The University Of Texas System Lung targeted anticancer therapies with liposomal annamycin

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
JPS5233639B1 (de) * 1971-01-20 1977-08-30
JPS5134915B2 (de) * 1974-07-27 1976-09-29
US3993754A (en) * 1974-10-09 1976-11-23 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome-encapsulated actinomycin for cancer chemotherapy
GB1499026A (en) * 1975-06-20 1978-01-25 Farmaceutici Italia Adriamycin esters
US4035566A (en) * 1975-09-25 1977-07-12 Sidney Farber Cancer Institute, Inc. N-trifluoroacetyladriamycin-14-alkanoates and therapeutic compositions containing same
CH621479A5 (de) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4460577A (en) * 1977-09-30 1984-07-17 Farmitalia Carlo Erba S.P.A. Pharmaceutical compositions consisting or consisting essentially of liposomes, and processes for making same
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
PL124284B1 (en) * 1979-10-17 1983-01-31 Politechnika Gdanska Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group
US4419348A (en) * 1981-04-27 1983-12-06 Georgetown University Anthracycline glycoside compositions, their use and preparation
IT1194381B (it) * 1982-08-27 1988-09-22 Contact Lens Mfg Ltd Protesi,lenti a contatto e polimeri per la loro fabbricazione
GR79729B (de) * 1982-12-20 1984-10-31 Univ Ohio State Res Found
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
US4537802A (en) * 1984-08-31 1985-08-27 Flanagan John J Floor finishing, cleaning and burnishing compositions containing ucon polymers, and method of use
GB8508079D0 (en) * 1985-03-28 1985-05-01 Erba Farmitalia Antitumor anthracyclines
EP0198765A3 (de) * 1985-04-09 1987-10-21 Georgetown University Herstellung von Liposomen
IE58981B1 (en) * 1985-10-15 1993-12-15 Vestar Inc Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles

Also Published As

Publication number Publication date
EP0358719B1 (de) 1991-10-30
DE3865966D1 (de) 1991-12-05
AU1933288A (en) 1988-12-21
AU609156B2 (en) 1991-04-26
JP2716178B2 (ja) 1998-02-18
JPH02503560A (ja) 1990-10-25
WO1988009166A1 (en) 1988-12-01
US4863739A (en) 1989-09-05
EP0358719A1 (de) 1990-03-21

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee