ATE72116T1 - Erhoehung der tetracyclinwirkung. - Google Patents

Erhoehung der tetracyclinwirkung.

Info

Publication number: ATE72116T1
Authority: AT; Austria
Prior art keywords: tetracycline; effects; increase; resistant; type antibiotics
Prior art date: 1982-11-18

Application number

AT83903900T

Other languages

English (en)

Inventor

Stuart B Levy

Original Assignee

Univ Tufts

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-18

Filing date

1983-11-17

Publication date

1992-02-15

1983-11-17 Application filed by Univ Tufts filed Critical Univ Tufts

1992-02-15 Application granted granted Critical

1992-02-15 Publication of ATE72116T1 publication Critical patent/ATE72116T1/de

Links

239000004098 Tetracycline Substances 0.000 title abstract 3
229960002180 tetracycline Drugs 0.000 title abstract 3
229930101283 tetracycline Natural products 0.000 title abstract 3
235000019364 tetracycline Nutrition 0.000 title abstract 3
150000003522 tetracyclines Chemical class 0.000 title abstract 3
239000003242 anti bacterial agent Substances 0.000 abstract 2
229940088710 antibiotic agent Drugs 0.000 abstract 2
206010034133 Pathogen resistance Diseases 0.000 abstract 1
230000001580 bacterial effect Effects 0.000 abstract 1
239000002981 blocking agent Substances 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
239000013612 plasmid Substances 0.000 abstract 1
230000035945 sensitivity Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT83903900T 1982-11-18 1983-11-17 Erhoehung der tetracyclinwirkung. ATE72116T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/442,688 US4806529A (en)	1982-11-18	1982-11-18	Tetracycline activity enhancement
PCT/US1983/001825 WO1984001895A1 (en)	1982-11-18	1983-11-17	Tetracycline activity enhancement

Publications (1)

Publication Number	Publication Date
ATE72116T1 true ATE72116T1 (de)	1992-02-15

Family

ID=23757747

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT83903900T ATE72116T1 (de)	1982-11-18	1983-11-17	Erhoehung der tetracyclinwirkung.

Country Status (8)

Country	Link
US (2)	US4806529A (de)
EP (1)	EP0126145B1 (de)
JP (1)	JPH0780774B2 (de)
AT (1)	ATE72116T1 (de)
AU (1)	AU2342284A (de)
CA (1)	CA1225332A (de)
DE (1)	DE3382503D1 (de)
WO (1)	WO1984001895A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5064821A (en) *	1982-11-18	1991-11-12	Trustees Of Tufts College	Method and compositions for overcoming tetracycline resistance within living cells
US5589470A (en) *	1990-02-26	1996-12-31	Trustees Of Tufts College	Reducing tetracycline resistance in living cells
WO1993008806A1 (en) *	1991-11-06	1993-05-13	Trustees Of Tufts College	Reducing tetracycline resistance in living cells
US5281628A (en) *	1991-10-04	1994-01-25	American Cyanamid Company	9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines
US5494903A (en) *	1991-10-04	1996-02-27	American Cyanamid Company	7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
USRE40183E1 (en)	1991-10-04	2008-03-25	Wyeth Holdings Corporation	7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US6756365B2 (en) *	1991-11-06	2004-06-29	Trustees Of Tufts College	Reducing tetracycline resistance in living cells
TW318189B (de) *	1991-12-06	1997-10-21	American Cyanamid Co
US5328902A (en) *	1992-08-13	1994-07-12	American Cyanamid Co.	7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5284963A (en) *	1992-08-13	1994-02-08	American Cyanamid Company	Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
US5420272A (en) *	1992-08-13	1995-05-30	American Cyanamid Company	7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
SG47520A1 (en) *	1992-08-13	1998-04-17	American Cyanamid Co	New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5371076A (en) *	1993-04-02	1994-12-06	American Cyanamid Company	9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
US5989832A (en) *	1995-04-21	1999-11-23	Microcide Pharmaceuticals, Inc.	Method for screening for non-tetracycline efflux pump inhibitors
US20020123637A1 (en) *	1998-01-23	2002-09-05	Stuart B. Levy	Pharmaceutically active compounds and methods of use thereof
US6346391B1 (en) *	1999-07-22	2002-02-12	Trustees Of Tufts College	Methods of reducing microbial resistance to drugs
US20020132798A1 (en) *	2000-06-16	2002-09-19	Nelson Mark L.	7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) *	2000-06-16	2004-11-11	Trustees Of Tufts College	7-N-substituted phenyl tetracycline compounds
AU2001268475A1 (en) *	2000-06-16	2002-01-02	Trustees Of Tufts College	7-phenyl-substituted tetracycline compounds
KR100674047B1 (ko)	2000-07-07	2007-01-25	트러스티즈 오브 터프츠 칼리지	9-치환된 미노사이클린 화합물
WO2002072506A2 (en) *	2001-03-13	2002-09-19	Paratek Pharmaceuticals, Inc.	7-pyrollyl tetracycline compounds and methods of use thereof
EP2332547A1 (de)	2001-07-13	2011-06-15	Paratek Pharmaceuticals, Inc.	Tetracyclinverbindungen zur Behandlung von entzündlicher Darmerkrankung
RU2230563C1 (ru) *	2003-02-10	2004-06-20	ЗАО "Курорт Усть-Качка"	Средство для повышения чувствительности микроорганизмов к антимикробным препаратам
WO2005009943A2 (en) *	2003-07-09	2005-02-03	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds
US20060287283A1 (en) *	2003-07-09	2006-12-21	Paratek Pharmaceuticals, Inc.	Prodrugs of 9-aminomethyl tetracycline compounds
UA83266C2 (en)	2003-12-08	2008-06-25	Уайет	Oxazole derivatives of tetracyclines
RU2255746C1 (ru) *	2004-01-08	2005-07-10	ЗАО "Курорт Усть-Качка"	Средство для повышения чувствительности микроорганизмов к антимикробным препаратам
EP2269978A3 (de) *	2004-10-25	2011-09-21	Paratek Pharmaceuticals, Inc.	Substituierte Tetracyclinverbindungen
CA2597212A1 (en)	2005-02-04	2006-08-10	Paratek Pharmaceuticals, Inc.	11a, 12-derivatives of tetracycline compounds
EP1848686A2 (de)	2005-02-15	2007-10-31	Wyeth	9-substituierte tetracycline
US20080241235A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en)	2005-06-24	2014-05-13	Medicis Pharmaceutical Corporation	Extended-release minocycline dosage forms
US7544373B2 (en) *	2007-04-02	2009-06-09	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en)	2005-06-24	2011-04-05	Medicis Pharmaceutical Corporation	Method for the treatment of acne
US8252776B2 (en)	2007-04-02	2012-08-28	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) *	2007-04-02	2009-06-02	Medicis Pharmaceutical Coropration	Minocycline oral dosage forms for the treatment of acne
US20070093455A1 (en) *	2005-07-21	2007-04-26	Paul Abato	10-substituted tetracyclines and methods of use thereof
RU2008108215A (ru) *	2005-08-31	2009-10-10	Вайет (Us)	9-аминокарбонилзамещенные производные глицилциклинов
CA2652347A1 (en)	2006-05-15	2007-11-22	Paratek Pharmaceuticals, Inc.	Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
EP2120963B1 (de)	2006-12-21	2018-09-12	Paratek Pharmaceuticals, Inc.	Substituierte tetracyclinverbindungen zur behandlung von entzündlichen hautstörungen
IL270446B2 (en) *	2006-12-21	2023-10-01	Paratek Pharm Innc	A tetracycline compound, a pharmaceutical preparation containing the tetracycline compound, and the tetracycline compound or the pharmaceutical preparation for the treatment of the tetracycline-responsive condition
US20080241197A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline dosage forms for the treatment of acne
JP2010523684A (ja)	2007-04-12	2010-07-15	パラテックファーマシューティカルズインコーポレイテッド	テトラサイクリン化合物を用いる、脊髄筋委縮症を治療するための方法
AU2009220171A1 (en)	2008-03-05	2009-09-11	Paratek Pharmaceuticals, Inc.	Minocycline compounds and methods of use thereof
JP2011517697A (ja) *	2008-04-14	2011-06-16	パラテックファーマシューティカルズインコーポレイテッド	置換テトラサイクリン化合物
WO2010017310A1 (en)	2008-08-06	2010-02-11	Medicis Pharmaceutical Corporation	Method for the treatment of acne and certain dosage forms thereof
US9561241B1 (en)	2011-06-28	2017-02-07	Medicis Pharmaceutical Corporation	Gastroretentive dosage forms for minocycline
US10383884B2 (en)	2016-11-01	2019-08-20	Paratek Pharmaceuticals, Inc.	9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (CABP)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3454697A (en) *	1965-06-08	1969-07-08	American Cyanamid Co	Tetracycline antibiotic compositions for oral use
NL7306746A (de) *	1972-05-24	1973-11-27
DE2442829A1 (de) *	1974-09-06	1976-03-18	Merck Patent Gmbh	Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4126680A (en) *	1977-04-27	1978-11-21	Pfizer Inc.	Tetracycline antibiotic compositions
AU522973B2 (en) *	1978-03-02	1982-07-08	Karl Kristian Kobs Kroyer	Preparing dry-laid fibrous products

1982
- 1982-11-18 US US06/442,688 patent/US4806529A/en not_active Expired - Lifetime
1983
- 1983-11-17 JP JP59500096A patent/JPH0780774B2/ja not_active Expired - Lifetime
- 1983-11-17 DE DE8383903900T patent/DE3382503D1/de not_active Expired - Lifetime
- 1983-11-17 AU AU23422/84A patent/AU2342284A/en not_active Abandoned
- 1983-11-17 AT AT83903900T patent/ATE72116T1/de not_active IP Right Cessation
- 1983-11-17 EP EP83903900A patent/EP0126145B1/de not_active Expired - Lifetime
- 1983-11-17 WO PCT/US1983/001825 patent/WO1984001895A1/en not_active Ceased
- 1983-11-18 CA CA000441466A patent/CA1225332A/en not_active Expired
1986
- 1986-04-11 US US06/850,843 patent/US5021407A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPS60500257A (ja)	1985-02-28
WO1984001895A1 (en)	1984-05-24
US4806529A (en)	1989-02-21
AU2342284A (en)	1984-06-04
EP0126145A1 (de)	1984-11-28
JPH0780774B2 (ja)	1995-08-30
US5021407A (en)	1991-06-04
EP0126145A4 (de)	1985-06-06
CA1225332A (en)	1987-08-11
DE3382503D1 (de)	1992-03-12
EP0126145B1 (de)	1992-01-29

Legal Events

Date	Code	Title	Description
1992-09-15	UEP	Publication of translation of european patent specification
2004-02-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
ATE72116T1 (de)	1992-02-15	Erhoehung der tetracyclinwirkung.
CA922907A (en)	1973-03-20	Fuel delivery system
CA961719A (en)	1975-01-28	Fuel injection systems
CA937471A (en)	1973-11-27	Fuel injection systems
GB1051686A (de)
AU1666570A (en)	1972-01-06	Fuel injector
AU2275670A (en)	1972-06-01	Fuel injection systems
JPS51113513A (en)	1976-10-06	Specific telephone service system
AU435923B2 (en)	1971-08-19	Guandine and amidine accelerators for vulcanization of fluorelastomers (application no 28113/71 was lodged on the 27th april, 1971 as an additional of this application)
AU2841871A (en)	1972-11-09	Fuel injection systems
AU443095B2 (en)	1972-07-27	Improvements in or relating in fuel injection systems
BR7017111D0 (pt)	1973-06-05	Rolo compressor aperfeicoado com quatro cilindros
CA930847A (en)	1973-07-24	Fuel injection system
AU441123B2 (en)	1971-10-14	Fuel injection system
CA807432A (en)	1969-03-04	Fuel injection system
CA936939A (en)	1973-11-13	Fuel injection system
CA940621A (en)	1974-01-22	Fuel injection system
AU434878B2 (en)	1973-04-10	Fuel injection system
CA829642A (en)	1969-12-16	Fuel injection system
AU451464B2 (en)	1971-12-23	Fuel injection systems
AU447001B2 (en)	1974-03-21	Fuel injection systems
CA809958A (en)	1969-04-08	Fuel injection systems
CA810450A (en)	1969-04-15	Fuel injection systems
AU436561B2 (en)	1973-06-06	Fuel injection systems
CA819465A (en)	1969-08-05	Fuel injection systems