ATE72458T1 - Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen. - Google Patents

Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen.

Info

Publication number
ATE72458T1
ATE72458T1 AT86302219T AT86302219T ATE72458T1 AT E72458 T1 ATE72458 T1 AT E72458T1 AT 86302219 T AT86302219 T AT 86302219T AT 86302219 T AT86302219 T AT 86302219T AT E72458 T1 ATE72458 T1 AT E72458T1
Authority
AT
Austria
Prior art keywords
ribosomes
cell cultures
mutant
protein
producing proteins
Prior art date
Application number
AT86302219T
Other languages
English (en)
Inventor
Boer Herman Albert De
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE72458T1 publication Critical patent/ATE72458T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT86302219T 1985-03-27 1986-03-26 Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen. ATE72458T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/716,781 US4772555A (en) 1985-03-27 1985-03-27 Dedicated ribosomes and their use
EP86302219A EP0196223B1 (de) 1985-03-27 1986-03-26 Zugeordnete Ribosomen und ihre Verwendung zur Herstellung von Proteinen aus Zellkulturen

Publications (1)

Publication Number Publication Date
ATE72458T1 true ATE72458T1 (de) 1992-02-15

Family

ID=24879402

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86302219T ATE72458T1 (de) 1985-03-27 1986-03-26 Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen.

Country Status (7)

Country Link
US (1) US4772555A (de)
EP (1) EP0196223B1 (de)
JP (1) JPS61224991A (de)
AT (1) ATE72458T1 (de)
DE (1) DE3683784D1 (de)
IE (1) IE58424B1 (de)
IL (1) IL78270A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232840A (en) * 1986-03-27 1993-08-03 Monsanto Company Enhanced protein production in bacteria by employing a novel ribosome binding site
US6970182B1 (en) * 1999-10-20 2005-11-29 National Instruments Corporation Image acquisition system and method for acquiring variable sized objects
FR2810675B1 (fr) * 2000-06-22 2002-09-27 Pf Medicament Construction modifiee en aval du codon d'initiation pour la surexpression de proteines recombinantes
WO2004003511A2 (en) 2002-07-01 2004-01-08 Wayne State University Methods and compositions for the identification of antibiotics that are not susceptible to antibiotic resistance
WO2006122224A1 (en) * 2005-05-11 2006-11-16 Wayne State University Methods and compositions for the identification of antibiotics that are not susceptible to antibiotic resistance in pseudomonas aeruginosa
US8178659B2 (en) 2005-05-11 2012-05-15 Wayne State University Targets for the identification of antibiotics that are not susceptible to antibiotic resistance
US8362203B2 (en) * 2009-02-10 2013-01-29 Wayne State University Non-natural peptides as models for the development of antibiotics
CN113891941A (zh) * 2019-03-28 2022-01-04 特拉维夫大学拉莫特有限公司 修饰翻译的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression

Also Published As

Publication number Publication date
IL78270A0 (en) 1986-07-31
IE58424B1 (en) 1993-09-22
DE3683784D1 (de) 1992-03-19
US4772555A (en) 1988-09-20
IL78270A (en) 1992-06-21
IE860800L (en) 1986-09-27
JPS61224991A (ja) 1986-10-06
EP0196223A3 (en) 1988-12-07
EP0196223B1 (de) 1992-02-05
EP0196223A2 (de) 1986-10-01

Similar Documents

Publication Publication Date Title
DE69939901D1 (de) Verfahren und materialien zur herstellung von glucosamin
DE68921364D1 (de) Verfahren zur Herstellung von Proteinen mittels rekombinanter DNA.
DE3762616D1 (de) Hydrierung von methylendianilin zur herstellung von bis-(para-aminocyclohexyl)methanen.
ATE286126T1 (de) Glialmitogene faktoren, ihre herstellung und verwendung
DE3486206D1 (de) Expressionssysteme für Hefe mit PyK-Promotoren enthaltenden Vektoren und Synthese von Fremdproteinen.
ATE91716T1 (de) Verfahren zur herstellung vielkettige polypeptide oder proteine.
DE3583194D1 (de) Verfahren zur herstellung von einem polypeptid mittels eines transformierten mikroorganismus, ein dazu geeigneter transformierter mikroorganismus, und zur herstellung dieser mikroorganismen geeignete dns sequenzen.
DE3688209D1 (de) Verfahren zur herstellung von kohlenstoffilamenten und durch dieses verfahren erhaltene kohlenstoffilamente.
ATE46536T1 (de) Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren.
ATE68830T1 (de) Verfahren zur erhoehung der ausbeute von heterologen proteinen, produziert durch zuechtung von rekombinanten bakterien.
BG60053B2 (bg) Метод за повишаване способността за получаване на антибиотик
KR840002031A (ko) Dna, 재조합 dna, 이들을 갖는 숙주 및 폴리펩타이드를 제조하는 방법
FI885679A0 (fi) Samuttryckning i eukariotiska celler.
KR960700346A (ko) 면역억제제의 제조방법 및 이에 사용되는 신규 미생물(a process for producing immunosuppressives and a novel microbial species to be employed therein)
ATE72458T1 (de) Zugeordnete ribosomen und ihre verwendung zur herstellung von proteinen aus zellkulturen.
ATE112574T1 (de) Igg-bindendes protein h, kodierendes gen dafür und verfahren zu seiner herstellung.
BR8108074A (pt) Sequencia de dna,plasmidio recombinante,ligadores de dna,cultura bacterial e processo para produzir taumatina
DE3787998D1 (de) ART-Nukleotidsegmente, -Vektoren, -Zellinien, Verfahren zur Herstellung und Verwendung.
DK1200561T3 (da) Rekombinant stabil celleklon, dens fremstilling og anvendelse
ATE124454T1 (de) Gentechnische herstellung von faktor xiiia.
DE3687948D1 (de) Verfahren und nukleinsaeure zur herstellung von lecithin: cholestrinacyltransferase.
ATE88216T1 (de) Erhoehung der expression von genen in mikroorganismen.
DE69529750D1 (de) Verbesserungen in der herstellung von proteinen in wirtszellen
EA199900256A1 (ru) Нуклеотидная и белковая последовательность маммастатина и способы применения
DE3685337D1 (de) Verfahren zur herstellung von amiden unter verwendung von mikroorganismen.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee