ATE46536T1 - Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren. - Google Patents

Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren.

Info

Publication number
ATE46536T1
ATE46536T1 AT84300298T AT84300298T ATE46536T1 AT E46536 T1 ATE46536 T1 AT E46536T1 AT 84300298 T AT84300298 T AT 84300298T AT 84300298 T AT84300298 T AT 84300298T AT E46536 T1 ATE46536 T1 AT E46536T1
Authority
AT
Austria
Prior art keywords
protein
vertebrate
wircells
production
sequence
Prior art date
Application number
AT84300298T
Other languages
English (en)
Inventor
Arthur David Levinson
Christian Clinton Simonsen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE46536T1 publication Critical patent/ATE46536T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Separation, Sorting, Adjustment, Or Bending Of Sheets To Be Conveyed (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT84300298T 1983-01-19 1984-01-18 Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren. ATE46536T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/459,152 US4713339A (en) 1983-01-19 1983-01-19 Polycistronic expression vector construction
EP84300298A EP0117058B1 (de) 1983-01-19 1984-01-18 Verfahren zur Herstellung von reifen Proteinen in Wirtzellen von Wirbeltieren

Publications (1)

Publication Number Publication Date
ATE46536T1 true ATE46536T1 (de) 1989-10-15

Family

ID=23823622

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84300298T ATE46536T1 (de) 1983-01-19 1984-01-18 Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren.

Country Status (13)

Country Link
US (1) US4713339A (de)
EP (1) EP0117058B1 (de)
JP (3) JPH0630609B2 (de)
KR (1) KR840007253A (de)
AT (1) ATE46536T1 (de)
AU (1) AU578011B2 (de)
CA (1) CA1301675C (de)
DE (1) DE3479815D1 (de)
DK (1) DK173928B1 (de)
ES (1) ES529022A0 (de)
IE (1) IE55852B1 (de)
NZ (1) NZ206841A (de)
ZA (1) ZA84377B (de)

Families Citing this family (312)

* Cited by examiner, † Cited by third party
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EP0117058B1 (de) 1989-09-20
DK20984A (da) 1984-07-20
ES8507179A1 (es) 1985-09-01
ES529022A0 (es) 1985-09-01
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EP0117058A3 (en) 1986-02-12
IE840095L (en) 1984-07-19
DE3479815D1 (en) 1989-10-26
DK173928B1 (da) 2002-02-25
JPH06165672A (ja) 1994-06-14
JPH08252091A (ja) 1996-10-01
US4713339A (en) 1987-12-15
AU578011B2 (en) 1988-10-13
IE55852B1 (en) 1991-01-30
JP2557605B2 (ja) 1996-11-27
KR840007253A (ko) 1984-12-06
JP2719512B2 (ja) 1998-02-25
NZ206841A (en) 1987-06-30
AU2353184A (en) 1984-07-26
CA1301675C (en) 1992-05-26
EP0117058A2 (de) 1984-08-29
ZA84377B (en) 1985-02-27
JPH0630609B2 (ja) 1994-04-27
JPS59173096A (ja) 1984-09-29

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