ATE73334T1 - Antioestrogenes arzneimittel zur perkutanen verabreichung. - Google Patents
Antioestrogenes arzneimittel zur perkutanen verabreichung.Info
- Publication number
- ATE73334T1 ATE73334T1 AT85900469T AT85900469T ATE73334T1 AT E73334 T1 ATE73334 T1 AT E73334T1 AT 85900469 T AT85900469 T AT 85900469T AT 85900469 T AT85900469 T AT 85900469T AT E73334 T1 ATE73334 T1 AT E73334T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- drug
- antioestrogenic
- percutaneous administration
- affections
- Prior art date
Links
- 230000001833 anti-estrogenic effect Effects 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
- 210000000481 breast Anatomy 0.000 abstract 2
- 229940046836 anti-estrogen Drugs 0.000 abstract 1
- 239000000328 estrogen antagonist Substances 0.000 abstract 1
- -1 p-dimethylaminoethoxyphenyl Chemical group 0.000 abstract 1
- 229960003387 progesterone Drugs 0.000 abstract 1
- 239000000186 progesterone Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8400927A FR2558373B1 (fr) | 1984-01-20 | 1984-01-20 | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| PCT/EP1984/000436 WO1985003228A1 (fr) | 1984-01-20 | 1984-12-21 | Medicament antioestrogene pour administration percutanee |
| EP85900469A EP0169214B1 (de) | 1984-01-20 | 1984-12-21 | Antiöstrogenes arzneimittel zur perkutanen verabreichung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE73334T1 true ATE73334T1 (de) | 1992-03-15 |
Family
ID=9300348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85900469T ATE73334T1 (de) | 1984-01-20 | 1984-12-21 | Antioestrogenes arzneimittel zur perkutanen verabreichung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4919937A (de) |
| EP (2) | EP0151326B1 (de) |
| JP (1) | JPH0667826B2 (de) |
| AT (1) | ATE73334T1 (de) |
| DE (1) | DE3485581D1 (de) |
| DK (1) | DK155143C (de) |
| FR (1) | FR2558373B1 (de) |
| WO (1) | WO1985003228A1 (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8604528D0 (en) * | 1986-02-24 | 1986-04-03 | Ici Plc | Therapeutic agents |
| IL93693A (en) * | 1989-03-10 | 2000-01-31 | Endorech Inc | Pharmaceutical compositions for the treatment of estrogen sensitive diseases |
| US5119827A (en) * | 1990-09-05 | 1992-06-09 | Board Of Regents, The University Of Texas System | Mechanisms of antiestrogen resistance in breast cancer |
| US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
| US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
| GB9207437D0 (en) * | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| US5543150A (en) * | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
| DE4407742C1 (de) * | 1994-03-08 | 1995-06-22 | Hexal Pharma Gmbh | Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat |
| JP2001500841A (ja) * | 1996-03-29 | 2001-01-23 | エス ヴェー パテントフェアヴェアツングス ゲゼルシャフト ミット ベシュレンクテル ハフツンク | 障害された皮下結合脂肪組織、とりわけ脂肪性浮腫の場合における皮膚を引きしめ滑らかにするための化粧品および化粧用組成物 |
| RU2123838C1 (ru) * | 1996-07-31 | 1998-12-27 | Акционерное общество открытого типа "Нижфарм" | Состав для лечения гирсутизма |
| US20020086856A1 (en) | 1998-03-18 | 2002-07-04 | Alfred Schmidt | Medicament for preventing and/or treating a mammary carcinoma, containing a steroidal aromatase inhibitor |
| EP0943333A1 (de) * | 1998-03-18 | 1999-09-22 | S.W. Patentverwertungs GmbH | Medikament zur Prophylaxe und/oder Behandlung des Mammakarzinoms enthaltend einen Hemmer der Bildung von Oestrogenen |
| FI982733L (fi) * | 1998-12-17 | 2000-06-18 | Orion Yhtymae Oyj | Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia |
| US7947275B2 (en) | 2000-05-10 | 2011-05-24 | Signe Biopharma, Inc. | Compositions and methods for demonstrating secretory immune system regulation of steroid hormone responsive cancer cell growth |
| US8119138B2 (en) * | 2000-05-10 | 2012-02-21 | Signe Biopharma Inc. | Anti-estrogen and immune modulator combinations for treating breast cancer |
| US7863011B2 (en) * | 2000-05-10 | 2011-01-04 | Signe Biopharma, Inc. | Screening method for predicting susceptibility to breast cancer |
| US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
| DE10054294A1 (de) * | 2000-11-02 | 2002-05-16 | Heinrich Wieland | Topische Behandlung bei der Mastalgie |
| WO2003041654A2 (en) * | 2001-11-14 | 2003-05-22 | Sirbasku David A | Anti-estrogen and immune modulator combinations for treating breast cancer |
| PL370889A1 (en) * | 2001-12-20 | 2005-05-30 | Femmepharma, Inc. | Vaginal delivery of drugs |
| EP1572171B1 (de) * | 2002-12-18 | 2009-04-22 | Laboratoires Besins International | Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen |
| EP1572178B1 (de) * | 2002-12-18 | 2006-05-03 | Laboratoires Besins International | Behandlung von mastalgie mit4-hydroxy-tamoxifen |
| US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
| EP1578421A4 (de) * | 2003-01-02 | 2009-04-22 | Femmepharma Holding Co Inc | Pharmazeutische präparate für diebehandlung von erkrankungen und pathologischen zuständen der brust |
| NZ542499A (en) * | 2003-04-01 | 2008-10-31 | Besins Int Lab | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| JP4682129B2 (ja) * | 2003-06-09 | 2011-05-11 | アセンド セラピュティクス インコーポレイテッド | 4−ヒドロキシタモキシフェンによる過剰瘢痕化の治療及び予防 |
| US7968532B2 (en) * | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| CA2549824C (en) * | 2003-12-15 | 2012-03-13 | Laboratoires Besins International | Use of 4-hydroxytamoxifen for the preparation of a medicament for the treatment of gynecomastia |
| EP1550440A1 (de) * | 2003-12-15 | 2005-07-06 | Laboratoires Besins International | Verwendung von 4-hydroxytamoxifen zur Herstellung eines Arzneimittels zur Behandlung von Gynäkomastie |
| US7507769B2 (en) * | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| US20050208139A1 (en) * | 2004-03-22 | 2005-09-22 | Ascend Therapeutics, Inc. | Chemically stable compositions of 4-hydroxy tamoxifen |
| NZ549817A (en) * | 2004-03-22 | 2010-06-25 | Besins Int Lab | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| EP1579856A1 (de) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | 4-Hydroxytamoxifen zur Behandlung von benignen Brusterkrankungen |
| EP1647271A1 (de) * | 2004-10-14 | 2006-04-19 | Laboratoires Besins International | Gelzubereitung enthaltend 4-Hydroxy tamoxifen. |
| MX2007004371A (es) * | 2004-10-14 | 2007-06-07 | Besins Int Lab | Formulaciones de 4-hidroxitamoxifen en gel. |
| US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
| DK2450041T3 (en) | 2005-10-12 | 2018-11-19 | Unimed Pharmaceuticals Llc | Enhanced testosterone gel for use in the treatment of hypogonadism |
| KR100850910B1 (ko) * | 2006-12-22 | 2008-08-07 | 삼성전자주식회사 | 블루투스 디바이스를 연결하기 위한 장치 및 방법 |
| US20080153789A1 (en) * | 2006-12-26 | 2008-06-26 | Femmepharma Holding Company, Inc. | Topical administration of danazol |
| US20110003000A1 (en) * | 2009-07-06 | 2011-01-06 | Femmepharma Holding Company, Inc. | Transvaginal Delivery of Drugs |
| AU2017312499B2 (en) | 2016-08-19 | 2023-02-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002097B1 (de) * | 1977-08-22 | 1981-08-05 | Imperial Chemical Industries Plc | Triphenylalken-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten |
| DE3046719C2 (de) * | 1980-12-11 | 1983-02-17 | Klinge Pharma GmbH, 8000 München | 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel |
| FR2515041A1 (fr) | 1981-10-26 | 1983-04-29 | Besins Jean | Medicament a base de progesterone pour le traitement des affections mammaires |
-
1984
- 1984-01-20 FR FR8400927A patent/FR2558373B1/fr not_active Expired
- 1984-12-19 EP EP84201920A patent/EP0151326B1/de not_active Expired
- 1984-12-21 WO PCT/EP1984/000436 patent/WO1985003228A1/fr not_active Ceased
- 1984-12-21 JP JP60500495A patent/JPH0667826B2/ja not_active Expired - Fee Related
- 1984-12-21 US US06/777,786 patent/US4919937A/en not_active Expired - Lifetime
- 1984-12-21 EP EP85900469A patent/EP0169214B1/de not_active Expired - Lifetime
- 1984-12-21 DE DE8585900469T patent/DE3485581D1/de not_active Expired - Lifetime
- 1984-12-21 AT AT85900469T patent/ATE73334T1/de not_active IP Right Cessation
-
1985
- 1985-09-17 DK DK420385A patent/DK155143C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| DK155143B (da) | 1989-02-20 |
| WO1985003228A1 (fr) | 1985-08-01 |
| DK420385A (da) | 1985-09-17 |
| JPH0667826B2 (ja) | 1994-08-31 |
| JPS61500914A (ja) | 1986-05-08 |
| EP0169214A1 (de) | 1986-01-29 |
| EP0151326A1 (de) | 1985-08-14 |
| FR2558373B1 (fr) | 1987-07-03 |
| FR2558373A1 (fr) | 1985-07-26 |
| EP0169214B1 (de) | 1992-03-11 |
| DK155143C (da) | 1989-07-03 |
| DK420385D0 (da) | 1985-09-17 |
| US4919937A (en) | 1990-04-24 |
| DE3485581D1 (de) | 1992-04-16 |
| EP0151326B1 (de) | 1989-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |