DK420385A - Antioestrogent laegemiddel til perkutan indgift - Google Patents
Antioestrogent laegemiddel til perkutan indgift Download PDFInfo
- Publication number
- DK420385A DK420385A DK420385A DK420385A DK420385A DK 420385 A DK420385 A DK 420385A DK 420385 A DK420385 A DK 420385A DK 420385 A DK420385 A DK 420385A DK 420385 A DK420385 A DK 420385A
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- percutive
- antioestrogent
- administration
- medicine
- Prior art date
Links
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
- 210000000481 breast Anatomy 0.000 abstract 2
- 229940046836 anti-estrogen Drugs 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000328 estrogen antagonist Substances 0.000 abstract 1
- -1 p-dimethylaminoethoxyphenyl Chemical group 0.000 abstract 1
- 229960003387 progesterone Drugs 0.000 abstract 1
- 239000000186 progesterone Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8400927 | 1984-01-20 | ||
| FR8400927A FR2558373B1 (fr) | 1984-01-20 | 1984-01-20 | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| EP8400436 | 1984-12-21 | ||
| PCT/EP1984/000436 WO1985003228A1 (fr) | 1984-01-20 | 1984-12-21 | Medicament antioestrogene pour administration percutanee |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK420385A true DK420385A (da) | 1985-09-17 |
| DK420385D0 DK420385D0 (da) | 1985-09-17 |
| DK155143B DK155143B (da) | 1989-02-20 |
| DK155143C DK155143C (da) | 1989-07-03 |
Family
ID=9300348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK420385A DK155143C (da) | 1984-01-20 | 1985-09-17 | Antioestrogent laegemiddel til behandling af benigne og canceroese tilstande i brystet |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4919937A (da) |
| EP (2) | EP0151326B1 (da) |
| JP (1) | JPH0667826B2 (da) |
| AT (1) | ATE73334T1 (da) |
| DE (1) | DE3485581D1 (da) |
| DK (1) | DK155143C (da) |
| FR (1) | FR2558373B1 (da) |
| WO (1) | WO1985003228A1 (da) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8604528D0 (en) * | 1986-02-24 | 1986-04-03 | Ici Plc | Therapeutic agents |
| ES2077675T3 (es) * | 1989-03-10 | 1995-12-01 | Endorecherche Inc | Terapia combinada para el tratamiento de enfermedades sensibles a los estrogenos. |
| US5119827A (en) * | 1990-09-05 | 1992-06-09 | Board Of Regents, The University Of Texas System | Mechanisms of antiestrogen resistance in breast cancer |
| US5705185A (en) * | 1991-09-25 | 1998-01-06 | Beta Pharmaceuticals Co. | Transdermal delivery of estradiol and process for manufacturing said device |
| US5518734A (en) * | 1991-09-25 | 1996-05-21 | Beta Pharmaceuticals Co. | Transdermal delivery system for estradiol and process for manufacturing said device |
| GB9207437D0 (en) * | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| US5543150A (en) * | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
| DE4407742C1 (de) * | 1994-03-08 | 1995-06-22 | Hexal Pharma Gmbh | Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat |
| DE59703511D1 (de) * | 1996-03-29 | 2001-06-13 | S W Patentverwaltungs Ges M B | Kosmetikum bzw. kosmetikzusammensetzung zur glättung und straffung der haut bei gestörtem unterhaut-binde-fettgewebe, insbesondere bei der "cellulite" |
| RU2123838C1 (ru) * | 1996-07-31 | 1998-12-27 | Акционерное общество открытого типа "Нижфарм" | Состав для лечения гирсутизма |
| EP0943333A1 (de) * | 1998-03-18 | 1999-09-22 | S.W. Patentverwertungs GmbH | Medikament zur Prophylaxe und/oder Behandlung des Mammakarzinoms enthaltend einen Hemmer der Bildung von Oestrogenen |
| US20020086856A1 (en) | 1998-03-18 | 2002-07-04 | Alfred Schmidt | Medicament for preventing and/or treating a mammary carcinoma, containing a steroidal aromatase inhibitor |
| FI982733L (fi) | 1998-12-17 | 2000-06-18 | Orion Yhtymae Oyj | Trifenyylietyleeniantiestrogeenien liukoisia koostumuksia |
| US7863011B2 (en) * | 2000-05-10 | 2011-01-04 | Signe Biopharma, Inc. | Screening method for predicting susceptibility to breast cancer |
| MXPA02011092A (es) | 2000-05-10 | 2004-08-19 | David A Sirbasku | Composiciones y metodos para demostrar la regulacion del sistema inmune secretor del crecimiento de la celula de cancer que responde a la hormona esteroidea. |
| US8119138B2 (en) * | 2000-05-10 | 2012-02-21 | Signe Biopharma Inc. | Anti-estrogen and immune modulator combinations for treating breast cancer |
| US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| DE10054294A1 (de) * | 2000-11-02 | 2002-05-16 | Heinrich Wieland | Topische Behandlung bei der Mastalgie |
| EP1515748A4 (en) * | 2001-11-14 | 2006-04-12 | David A Sirbasku | ANTIESTROGEN AND IMMUNOMODULATOR COMBINATIONS FOR THE TREATMENT OF BREAST CANCER |
| JP2005513080A (ja) | 2001-12-20 | 2005-05-12 | フェムファーマ, インコーポレイテッド | 薬物の膣送達 |
| DE60327363D1 (de) | 2002-12-18 | 2009-06-04 | Besins Int Lab | Verringerung der dichte des brustgewebes durch 4-hydroxy tamoxifen |
| MXPA05006526A (es) * | 2002-12-18 | 2006-02-17 | Besins Int Lab | Tratamiento de mastalgia con 4-hidroxi tamoxifen. |
| US9173836B2 (en) | 2003-01-02 | 2015-11-03 | FemmeParma Holding Company, Inc. | Pharmaceutical preparations for treatments of diseases and disorders of the breast |
| MXPA05007266A (es) * | 2003-01-02 | 2006-01-17 | Femmepharma Holding Co Inc | Preparaciones farmaceuticas para tratamientos de enfermedades y trastornos del seno. |
| ES2456958T3 (es) | 2003-04-01 | 2014-04-24 | Besins Healthcare Luxembourg Sarl | Formulaciones para prevención y tratamiento de cáncer de seno con 4-hidroxi tamoxifen |
| JP4682129B2 (ja) * | 2003-06-09 | 2011-05-11 | アセンド セラピュティクス インコーポレイテッド | 4−ヒドロキシタモキシフェンによる過剰瘢痕化の治療及び予防 |
| EP1550440A1 (en) * | 2003-12-15 | 2005-07-06 | Laboratoires Besins International | Use of 4-hydroxytamoxifen for the preparation of a medicament for the treatment of gynecomastia |
| PT1694319E (pt) * | 2003-12-15 | 2008-10-24 | Besins Int Lab | Utilização de 4-hidroxi-tamoxifeno na preparação de um medicamento para o tratamento da ginecomastia |
| US7968532B2 (en) * | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| US20050208139A1 (en) * | 2004-03-22 | 2005-09-22 | Ascend Therapeutics, Inc. | Chemically stable compositions of 4-hydroxy tamoxifen |
| US7507769B2 (en) * | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| PT1748770E (pt) * | 2004-03-22 | 2008-07-16 | Besins Int Lab | Tratamento e prevenção de doença benigna da mama com 4-hidroxi-tamoxifeno |
| EP1579856A1 (en) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| EP1647271A1 (en) * | 2004-10-14 | 2006-04-19 | Laboratoires Besins International | 4-Hydroxy tamoxifen gel formulations |
| EA011295B1 (ru) * | 2004-10-14 | 2009-02-27 | Лаборатуар Безен Энтернасьональ | Рецептура геля с 4-гидрокситамоксифеном |
| US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
| ES3012497T3 (en) | 2005-10-12 | 2025-04-09 | Besins Healthcare Lu Sarl | Improved testosterone gel and method of use |
| KR100850910B1 (ko) * | 2006-12-22 | 2008-08-07 | 삼성전자주식회사 | 블루투스 디바이스를 연결하기 위한 장치 및 방법 |
| EP2104489A2 (en) * | 2006-12-26 | 2009-09-30 | FemmePharma Holding Company, Inc. | Topical administration of danazol |
| US20110003000A1 (en) * | 2009-07-06 | 2011-01-06 | Femmepharma Holding Company, Inc. | Transvaginal Delivery of Drugs |
| WO2018034945A1 (en) | 2016-08-19 | 2018-02-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Selective estrogen-receptor modulators (serms) confer protection against photoreceptor degeneration |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002097B1 (en) * | 1977-08-22 | 1981-08-05 | Imperial Chemical Industries Plc | Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them |
| DE3046719C2 (de) * | 1980-12-11 | 1983-02-17 | Klinge Pharma GmbH, 8000 München | 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel |
| FR2515041A1 (fr) * | 1981-10-26 | 1983-04-29 | Besins Jean | Medicament a base de progesterone pour le traitement des affections mammaires |
-
1984
- 1984-01-20 FR FR8400927A patent/FR2558373B1/fr not_active Expired
- 1984-12-19 EP EP84201920A patent/EP0151326B1/fr not_active Expired
- 1984-12-21 EP EP85900469A patent/EP0169214B1/fr not_active Expired - Lifetime
- 1984-12-21 AT AT85900469T patent/ATE73334T1/de not_active IP Right Cessation
- 1984-12-21 US US06/777,786 patent/US4919937A/en not_active Expired - Lifetime
- 1984-12-21 WO PCT/EP1984/000436 patent/WO1985003228A1/fr not_active Ceased
- 1984-12-21 DE DE8585900469T patent/DE3485581D1/de not_active Expired - Lifetime
- 1984-12-21 JP JP60500495A patent/JPH0667826B2/ja not_active Expired - Fee Related
-
1985
- 1985-09-17 DK DK420385A patent/DK155143C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| DE3485581D1 (de) | 1992-04-16 |
| ATE73334T1 (de) | 1992-03-15 |
| EP0169214B1 (fr) | 1992-03-11 |
| EP0151326B1 (fr) | 1989-07-12 |
| EP0151326A1 (fr) | 1985-08-14 |
| DK420385D0 (da) | 1985-09-17 |
| JPH0667826B2 (ja) | 1994-08-31 |
| EP0169214A1 (fr) | 1986-01-29 |
| US4919937A (en) | 1990-04-24 |
| FR2558373B1 (fr) | 1987-07-03 |
| DK155143C (da) | 1989-07-03 |
| JPS61500914A (ja) | 1986-05-08 |
| WO1985003228A1 (fr) | 1985-08-01 |
| FR2558373A1 (fr) | 1985-07-26 |
| DK155143B (da) | 1989-02-20 |
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