ATE73348T1 - Thymidinkinase-deletionsmutanten von bovinem herpesvirus-1, diese enthaltende impfstoffe gegen bovine rhinotracheitis und verfahren zu deren herstellung und verwendung. - Google Patents

Thymidinkinase-deletionsmutanten von bovinem herpesvirus-1, diese enthaltende impfstoffe gegen bovine rhinotracheitis und verfahren zu deren herstellung und verwendung.

Info

Publication number
ATE73348T1
ATE73348T1 AT86115455T AT86115455T ATE73348T1 AT E73348 T1 ATE73348 T1 AT E73348T1 AT 86115455 T AT86115455 T AT 86115455T AT 86115455 T AT86115455 T AT 86115455T AT E73348 T1 ATE73348 T1 AT E73348T1
Authority
AT
Austria
Prior art keywords
thymidine kinase
methods
bovine
manufacture
deletion mutants
Prior art date
Application number
AT86115455T
Other languages
English (en)
Inventor
Malon Kit
Saul Kit
Original Assignee
Novagene Inc
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novagene Inc, Baylor College Medicine filed Critical Novagene Inc
Application granted granted Critical
Publication of ATE73348T1 publication Critical patent/ATE73348T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/813—Viral vaccine for bovine species, e.g. cattle
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/822—Drug, bio-affecting and body treating compositions involving tk- virus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/22—Viral peptide or viral protein
    • Y10S930/224—Herpes related

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT86115455T 1985-11-12 1986-11-07 Thymidinkinase-deletionsmutanten von bovinem herpesvirus-1, diese enthaltende impfstoffe gegen bovine rhinotracheitis und verfahren zu deren herstellung und verwendung. ATE73348T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/796,840 US4703011A (en) 1985-11-12 1985-11-12 Thymidine kinase deletion mutants of bovine herpesvirus-1
EP86115455A EP0226029B1 (de) 1985-11-12 1986-11-07 Thymidinkinase-Deletionsmutanten von bovinem Herpesvirus-1, diese enthaltende Impfstoffe gegen bovine Rhinotracheitis und Verfahren zu deren Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE73348T1 true ATE73348T1 (de) 1992-03-15

Family

ID=25169196

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86115455T ATE73348T1 (de) 1985-11-12 1986-11-07 Thymidinkinase-deletionsmutanten von bovinem herpesvirus-1, diese enthaltende impfstoffe gegen bovine rhinotracheitis und verfahren zu deren herstellung und verwendung.

Country Status (8)

Country Link
US (2) US4703011A (de)
EP (1) EP0226029B1 (de)
JP (1) JPH0811064B2 (de)
AT (1) ATE73348T1 (de)
AU (1) AU598764B2 (de)
CA (1) CA1280986C (de)
DE (1) DE3684255D1 (de)
ES (1) ES2035818T3 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128128A (en) * 1985-07-29 1992-07-07 The Upjohn Company Virus vaccine
EP0231209B1 (de) * 1985-07-29 1991-02-06 The Upjohn Company Virus-impfstoff
US5223424A (en) * 1985-09-06 1993-06-29 Prutech Research And Development Attenuated herpesviruses and herpesviruses which include foreign DNA encoding an amino acid sequence
US5763269A (en) * 1985-09-06 1998-06-09 Syntro Corporation Recombinant infectious bovine rhinotrocheitis virus
US5352575A (en) * 1985-10-04 1994-10-04 The Upjohn Company Pseudorabies virus protein
US4703011A (en) * 1985-11-12 1987-10-27 Novagene, Inc. Thymidine kinase deletion mutants of bovine herpesvirus-1
US6251634B1 (en) 1985-11-26 2001-06-26 Pharmacia & Upjohn Company Pseudorabies virus protein
EP0256092B1 (de) * 1986-01-27 1998-04-08 Syntro Corporation Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten
US5593873A (en) * 1986-01-27 1997-01-14 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US6410033B1 (en) 1987-07-27 2002-06-25 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US4992051A (en) * 1987-11-03 1991-02-12 Novagene, Inc. Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same
US5672344A (en) * 1987-12-30 1997-09-30 The Regents Of The University Of Michigan Viral-mediated gene transfer system
JPH0235079A (ja) * 1988-01-26 1990-02-05 Novagene Inc 感染性ウシ鼻気管炎ウイルスの挿入突然変異体
US5324664A (en) * 1988-08-08 1994-06-28 The Upjohn Company Herpes virus thymidien kinase-encoding DNA
AU625584B2 (en) * 1989-03-08 1992-07-16 Health Research Inc. Recombinant poxvirus host selection system
ES2091243T3 (es) * 1989-05-22 1996-11-01 Hoffmann La Roche Metodos de señalizacion y rastreo de materiales mediante acidos nucleicos.
NL9100989A (nl) * 1991-06-07 1993-01-04 Stichting Centr Diergeneeskund Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1.
CA2113641A1 (en) * 1991-07-18 1993-02-04 Mark D. Cochran Recombinant infectious bovine rhinotracheitis virus
US5874279A (en) * 1991-07-18 1999-02-23 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US5855902A (en) * 1992-11-02 1999-01-05 Protatek International, Inc. Method of administering a vaccine comprising tritrichomonas foetus membrane surface antigens between 45 and 300 kilopaltons
US5545523A (en) * 1993-05-28 1996-08-13 Cornell Research Foundation, Inc. Methods of detecting bovine herpesvirus 1 (BHV-1) in semen by nucleic acid amplification
ES2074965B1 (es) * 1994-01-31 1996-05-01 Hipra Lab Sa Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
US6221360B1 (en) 1996-02-26 2001-04-24 Kansas State University Research Foundation Infectious bovine rhinotracheitis vaccines and methods
US6284251B1 (en) 1996-02-26 2001-09-04 Kansas State University Research Foundation BHV-1 gene-deleted virus vaccine
US5851804A (en) * 1996-05-06 1998-12-22 Apollon, Inc. Chimeric kanamycin resistance gene
CN102649948B (zh) * 2011-02-23 2016-05-25 华中农业大学 牛传染性鼻气管炎ΔTK/ΔgE基因缺失标志活疫苗及制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634587A (en) * 1969-11-06 1972-01-11 Ralston Purina Co Method of immunizing cattle against bovine respiratory disease syndrome
US3925544A (en) * 1971-07-12 1975-12-09 Univ Southern Illinois Bovine vaccines and methods of making and using same
US3907986A (en) 1972-12-18 1975-09-23 Rit Rech Ind Therapeut Live attenuated infectious bovine rhinotracheitis virus vaccines and preparation thereof
US4132775A (en) 1973-12-03 1979-01-02 Richardson-Merrell Inc. Infectious bovine rhinotracheitis virus vaccine and method of preparing and using the same
US4291019A (en) * 1979-07-09 1981-09-22 Iowa State University Research Foundation, Inc. Vaccine for infectious bovine rhinotracheitis
EP0074808A3 (de) * 1981-09-16 1984-07-04 University Patents, Inc. Rekombinantes Verfahren und Materialien
CA1237668A (en) * 1983-02-25 1988-06-07 Novagene Inc. Thymidine kinase-negative temperature resistant bovine herpes-virus-1 mutant as vaccine
GB8305323D0 (en) * 1983-02-25 1983-03-30 Baylor College Medicine Infectious bovine rhinotracheitis vaccine
NL8303501A (nl) * 1983-10-12 1985-05-01 Centraal Diergeneeskundig Inst Deletiemutant van een herpesvirus en vaccin, dat dit virus bevat.
US4514497B1 (en) * 1983-12-30 1998-02-24 Novagene Inc Modified live pseudorabies viruses
US4569849A (en) * 1984-12-19 1986-02-11 Leno Codino Process for making lasagna
US4703011A (en) * 1985-11-12 1987-10-27 Novagene, Inc. Thymidine kinase deletion mutants of bovine herpesvirus-1

Also Published As

Publication number Publication date
AU598764B2 (en) 1990-07-05
DE3684255D1 (de) 1992-04-16
JPS62118881A (ja) 1987-05-30
EP0226029B1 (de) 1992-03-11
EP0226029A1 (de) 1987-06-24
AU6489986A (en) 1987-05-14
CA1280986C (en) 1991-03-05
US4824667A (en) 1989-04-25
US4703011A (en) 1987-10-27
ES2035818T3 (es) 1993-05-01
JPH0811064B2 (ja) 1996-02-07

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