ATE74276T1 - Antivirale kombinationen und zusammensetzungen dafuer. - Google Patents

Antivirale kombinationen und zusammensetzungen dafuer.

Info

Publication number
ATE74276T1
ATE74276T1 AT89306468T AT89306468T ATE74276T1 AT E74276 T1 ATE74276 T1 AT E74276T1 AT 89306468 T AT89306468 T AT 89306468T AT 89306468 T AT89306468 T AT 89306468T AT E74276 T1 ATE74276 T1 AT E74276T1
Authority
AT
Austria
Prior art keywords
compositions
ribonucleotide reductase
antiviral combinations
antiviral
combinations
Prior art date
Application number
AT89306468T
Other languages
English (en)
Inventor
Todd Andrew Blumenkopf
Thomas Spector
Devron Randolph Averett
Robert William Morrison Jr
Eric Cleveland Bigham
Virgil Lee Styles
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE74276T1 publication Critical patent/ATE74276T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT89306468T 1988-06-27 1989-06-26 Antivirale kombinationen und zusammensetzungen dafuer. ATE74276T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888815241A GB8815241D0 (en) 1988-06-27 1988-06-27 Antiviral combinations & compounds therefor
EP89306468A EP0349243B1 (de) 1988-06-27 1989-06-26 Antivirale Kombinationen und Zusammensetzungen dafür

Publications (1)

Publication Number Publication Date
ATE74276T1 true ATE74276T1 (de) 1992-04-15

Family

ID=10639423

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89306468T ATE74276T1 (de) 1988-06-27 1989-06-26 Antivirale kombinationen und zusammensetzungen dafuer.

Country Status (19)

Country Link
US (3) US5175165A (de)
EP (1) EP0349243B1 (de)
JP (1) JPH0245423A (de)
KR (1) KR910000149A (de)
AT (1) ATE74276T1 (de)
AU (1) AU626304B2 (de)
DE (1) DE68901111D1 (de)
DK (1) DK315889A (de)
ES (1) ES2031357T3 (de)
FI (1) FI893112A7 (de)
GB (1) GB8815241D0 (de)
GR (1) GR3005067T3 (de)
HU (1) HU206264B (de)
IE (1) IE64496B1 (de)
IL (1) IL90750A0 (de)
MY (1) MY106304A (de)
NZ (1) NZ229711A (de)
PT (1) PT90972B (de)
ZA (1) ZA894835B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
US5164395A (en) * 1988-06-27 1992-11-17 Burroughs Wellcome Co. Antiviral acetyl pyridine derivative or said acetyl pyridine derivative in combination with acyclovir
US5674849A (en) * 1990-10-24 1997-10-07 Allelix Biopharmaceuticals Inc. Anti-viral compositions
CA2033447C (en) * 1990-12-31 1999-08-31 Robert Deziel Synergistic combination for treating herpes infections
CA2033448C (en) * 1990-12-31 1996-11-26 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Antiherpes compositions and method of use
US5580571A (en) * 1991-10-15 1996-12-03 Hostetler; Karl Y. Nucleoside analogues
US5879700A (en) * 1991-10-15 1999-03-09 Hostetler; Karl Y. Nucleoside analogue phosphates for topical use
US6015573A (en) * 1993-05-12 2000-01-18 Hostetler; Karl Y. Nucleoside phosphate therapy for viral infection
AU701574B2 (en) * 1993-05-12 1999-02-04 Karl Y. Hostetler Acyclovir derivatives for topical use
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
GB9315755D0 (en) * 1993-07-30 1993-09-15 Wellcome Found Stabilized formulation
WO1996001638A1 (en) * 1994-07-11 1996-01-25 Hoechst Marion Roussel, Inc. Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
EP0831873A4 (de) 1995-06-07 2002-07-17 Trimeris Inc Die behandlung von hiv und anderen viralen infektionen mit der kombinationstherapie
US20030212051A1 (en) * 2001-04-06 2003-11-13 Polli James E Bile acid containing prodrugs with enhanced bioavailabilty
CN1968699B (zh) 2004-05-19 2010-12-15 爱密斯菲尔科技公司 阿昔洛韦制剂
JP4972062B2 (ja) * 2008-03-17 2012-07-11 メディヴィル・アクチエボラーグ 抗ウイルス製剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4777166A (en) * 1982-03-30 1988-10-11 The United States Of America As Represented By The Secretary Of The Army 2-acetylpyridine thiosemicarbazone compositions as anitviral agents
US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
GB8320308D0 (en) * 1983-07-28 1983-09-01 Wellcome Found Antiviral combinations
US4606917A (en) * 1984-10-03 1986-08-19 Syntex (U.S.A) Inc. Synergistic antiviral composition
US4751221A (en) * 1985-10-18 1988-06-14 Sloan-Kettering Institute For Cancer Research 2-fluoro-arabinofuranosyl purine nucleosides
US4829055A (en) * 1987-01-23 1989-05-09 Naficy Sadeque S Method of treatment for herpes infections of external tissues
GB8815241D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Antiviral combinations & compounds therefor
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8823319D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds

Also Published As

Publication number Publication date
GR3005067T3 (de) 1993-05-24
FI893112L (fi) 1989-12-28
HUT52379A (en) 1990-07-28
IE64496B1 (en) 1995-08-09
DE68901111D1 (de) 1992-05-07
HU206264B (en) 1992-10-28
ZA894835B (en) 1991-02-27
KR910000149A (ko) 1991-01-29
PT90972B (pt) 1995-01-31
JPH0245423A (ja) 1990-02-15
EP0349243A3 (en) 1990-07-11
DK315889D0 (da) 1989-06-26
US5021437A (en) 1991-06-04
PT90972A (pt) 1989-12-29
US5175165A (en) 1992-12-29
EP0349243A2 (de) 1990-01-03
ES2031357T3 (es) 1992-12-01
FI893112A7 (fi) 1989-12-28
AU626304B2 (en) 1992-07-30
US5393883A (en) 1995-02-28
DK315889A (da) 1989-12-28
NZ229711A (en) 1992-08-26
FI893112A0 (fi) 1989-06-26
GB8815241D0 (en) 1988-08-03
MY106304A (en) 1995-04-29
EP0349243B1 (de) 1992-04-01
AU3702689A (en) 1990-02-01
IE892060L (en) 1989-12-27
IL90750A0 (en) 1990-01-18

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