ATE75607T1 - Mehrschichtige granula. - Google Patents

Mehrschichtige granula.

Info

Publication number
ATE75607T1
ATE75607T1 AT89101806T AT89101806T ATE75607T1 AT E75607 T1 ATE75607 T1 AT E75607T1 AT 89101806 T AT89101806 T AT 89101806T AT 89101806 T AT89101806 T AT 89101806T AT E75607 T1 ATE75607 T1 AT E75607T1
Authority
AT
Austria
Prior art keywords
layered
granula
releasing layer
layer
slow
Prior art date
Application number
AT89101806T
Other languages
English (en)
Inventor
Shigeru Aoki
Keizo Uesugi
Shigeru Sakashita
Masayoshi Kasai
Masanori Kayano
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE75607T1 publication Critical patent/ATE75607T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Glass Compositions (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT89101806T 1988-02-03 1989-02-02 Mehrschichtige granula. ATE75607T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63023215A JP2643222B2 (ja) 1988-02-03 1988-02-03 多重層顆粒
EP89101806A EP0327086B1 (de) 1988-02-03 1989-02-02 Mehrschichtige Granula

Publications (1)

Publication Number Publication Date
ATE75607T1 true ATE75607T1 (de) 1992-05-15

Family

ID=12104439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89101806T ATE75607T1 (de) 1988-02-03 1989-02-02 Mehrschichtige granula.

Country Status (11)

Country Link
US (1) US4994279A (de)
EP (1) EP0327086B1 (de)
JP (1) JP2643222B2 (de)
KR (1) KR910004582B1 (de)
CN (1) CN1031036C (de)
AT (1) ATE75607T1 (de)
CA (1) CA1337899C (de)
DE (1) DE68901384D1 (de)
ES (1) ES2031290T3 (de)
PH (1) PH26515A (de)
PT (1) PT89600B (de)

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ES2129356B1 (es) * 1997-03-26 2000-01-16 Pierre Fabre Iberica S A Forma farmaceutica de liberacion prolongada y procedimiento para su o btencion.
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EP0928610A1 (de) * 1998-01-08 1999-07-14 Development Center For Biotechnology Tacrine enthaltende Dosierungsform zur kontrollierten Freigabe
UA69413C2 (uk) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
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US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
CN100391438C (zh) * 1999-09-14 2008-06-04 史密丝克莱恩比彻姆公司 制备水性包被小球粒的方法
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SI1551372T1 (en) 2002-09-20 2018-08-31 Alpharma Pharmaceuticals Llc SUBVENCATION DATA AND RELATED CONSTRUCTIONS AND PROCEDURES
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
US20070224269A1 (en) * 2004-06-10 2007-09-27 Rubino Orapin P Controlled Release Pharmaceutical Formulation
AU2005320547B2 (en) * 2004-12-27 2009-02-05 Eisai R & D Management Co., Ltd. Method for stabilizing anti-dementia drug
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
EP2719378B1 (de) * 2006-06-19 2016-08-31 Alpharma Pharmaceuticals LLC Pharmazeutische Zusammensetzungen
AU2007322269A1 (en) * 2006-10-11 2008-05-29 Alpharma Pharmaceuticals, Llc Pharmaceutical compositions
US8486452B2 (en) * 2007-07-20 2013-07-16 Mylan Pharmaceuticals Inc. Stabilized tolterodine tartrate formulations
US8110226B2 (en) * 2007-07-20 2012-02-07 Mylan Pharmaceuticals Inc. Drug formulations having inert sealed cores
WO2009020595A2 (en) * 2007-08-03 2009-02-12 Shaklee Corporation Nutritional supplement system
US9763989B2 (en) 2007-08-03 2017-09-19 Shaklee Corporation Nutritional supplement system
US8323695B2 (en) * 2007-08-13 2012-12-04 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
IL199781A0 (en) 2009-07-09 2010-05-17 Yohai Zorea Heat resistant probiotic compositions and healthy food comprising them
US8623418B2 (en) * 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
EP2224808A4 (de) * 2007-12-17 2013-11-27 Alpharma Pharmaceuticals Llc Pharmazeutische zusammensetzung
CA2709905A1 (en) * 2007-12-17 2009-06-25 Alfred Liang Abuse-resistant oxycodone composition
US20100151014A1 (en) * 2008-12-16 2010-06-17 Alpharma Pharmaceuticals, Llc Pharmaceutical composition
ES2597038T3 (es) 2010-12-06 2017-01-13 Degama Berrier Ltd. Composición y método para mejorar la estabilidad y extender la vida útil de bacterias probióticas y productos alimenticios de las mismas
US10543175B1 (en) 2013-05-17 2020-01-28 Degama Berrier Ltd. Film composition and methods for producing the same
CA2936746C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
CN106035323B (zh) * 2016-05-25 2018-12-11 广西南宁农事帮农业科技服务有限公司 一种缓释农药颗粒剂及其制备方法
CN107188722A (zh) * 2017-07-12 2017-09-22 山东棉花研究中心 一种组合式短季棉专用配方肥
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

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US2921883A (en) * 1957-05-03 1960-01-19 Smith Kline French Lab Novel coating material for medicaments
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JPS55153715A (en) * 1979-05-18 1980-11-29 Nikken Kagaku Kk Prolonged granule of theophylline
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JPS59155309A (ja) * 1983-02-22 1984-09-04 Teijin Ltd 活性型ビタミンｄ↓３類組成物
DE3403329A1 (de) * 1984-02-01 1985-08-01 Horst Dr. 4019 Monheim Zerbe Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe
US4572883A (en) * 1984-06-11 1986-02-25 Xerox Corporation Electrophotographic imaging member with charge injection layer
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JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒

Also Published As

Publication number Publication date
KR890012636A (ko) 1989-09-18
CA1337899C (en) 1996-01-09
CN1031036C (zh) 1996-02-21
JP2643222B2 (ja) 1997-08-20
DE68901384D1 (de) 1992-06-11
PH26515A (en) 1992-08-07
PT89600B (pt) 1994-01-31
PT89600A (pt) 1989-10-04
KR910004582B1 (ko) 1991-07-06
ES2031290T3 (es) 1992-12-01
JPH01197433A (ja) 1989-08-09
CN1037082A (zh) 1989-11-15
EP0327086A2 (de) 1989-08-09
EP0327086A3 (en) 1989-09-06
US4994279A (en) 1991-02-19
EP0327086B1 (de) 1992-05-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee