ATE75743T1 - Hydrazinderivate und ihre verwendung. - Google Patents
Hydrazinderivate und ihre verwendung.Info
- Publication number
- ATE75743T1 ATE75743T1 AT85112762T AT85112762T ATE75743T1 AT E75743 T1 ATE75743 T1 AT E75743T1 AT 85112762 T AT85112762 T AT 85112762T AT 85112762 T AT85112762 T AT 85112762T AT E75743 T1 ATE75743 T1 AT E75743T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrazine derivatives
- formulaand
- exhibited
- pharmaceutically acceptable
- acceptable salts
- Prior art date
Links
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical class NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/658,849 US4610824A (en) | 1984-10-09 | 1984-10-09 | Hydrazide derivatives of monocyclic beta-lactam antibiotics |
| EP85112762A EP0177940B1 (de) | 1984-10-09 | 1985-10-08 | Hydrazinderivate und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE75743T1 true ATE75743T1 (de) | 1992-05-15 |
Family
ID=24642965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85112762T ATE75743T1 (de) | 1984-10-09 | 1985-10-08 | Hydrazinderivate und ihre verwendung. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4610824A (de) |
| EP (1) | EP0177940B1 (de) |
| JP (2) | JPH0647588B2 (de) |
| AT (1) | ATE75743T1 (de) |
| DE (1) | DE3585980D1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4775670A (en) * | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
| US4632985A (en) * | 1985-06-03 | 1986-12-30 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
| US4638062A (en) * | 1985-06-17 | 1987-01-20 | E. R. Squibb & Sons, Inc. | 3-acylamino-2-oxo-1-azetidinesulfonic acids |
| FI872879A7 (fi) * | 1986-07-21 | 1988-01-22 | Sankei Yakuhin Kk | --laktamfoerening, foerfarande foer dess framstaellning, denna innehaollande laekemedelskomposition foer behandling av sjukdom med bakterieinfektion samt mellanprodukter foer dess syntes. |
| US4904775A (en) * | 1988-05-16 | 1990-02-27 | E. R. Squibb & Sons, Inc. | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics |
| CA2024282A1 (en) * | 1989-09-21 | 1991-03-22 | Peter H. Ermann | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics |
| GB8928373D0 (en) * | 1989-12-15 | 1990-02-21 | Erba Carlo Spa | Beta-lactam derivatives |
| US5030724A (en) * | 1990-01-22 | 1991-07-09 | E. R. Squibb & Sons, Inc. | Monobactam hydrazides containing catechol sulfonic acid groups |
| ZA918014B (en) * | 1990-11-05 | 1992-07-29 | Squibb & Sons Inc | Heteroaroyl derivatives of monocyclic beta-lactam antibiotics |
| US5250691A (en) * | 1991-09-09 | 1993-10-05 | E. R. Squibb & Sons, Inc. | Heteroaryl derivatives of monocyclic beta-lactam antibiotics |
| DE19654920A1 (de) | 1996-06-26 | 1998-01-08 | Gruenenthal Gmbh | Neue synthetische Catecholderivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE19625524C2 (de) * | 1996-06-26 | 2000-11-30 | Gruenenthal Gmbh | Neue synthetische Catechol-Antibiotika-Konjugate und diese enthaltende Arzneimittel |
| US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
| DE122011100043I1 (de) | 2000-12-27 | 2011-12-15 | Gilead Sciences Inc | Inhalierbares aztreonam zur behandlung und vorbeugung von bakteriellen lungeninfektionen. |
| US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| MX373444B (es) | 2014-03-24 | 2020-04-30 | Novartis Ag | Compuestos organicos de monobactam para el tratamiento de infecciones bacterianas. |
| PL3353175T3 (pl) | 2015-09-23 | 2021-02-22 | Novartis Ag | Sole i postacie stałe antybiotyku monobaktamowego |
| JP7235718B2 (ja) | 2017-08-02 | 2023-03-08 | ノバルティス アーゲー | モノバクタム系抗生物質およびその中間体を製造するための化学的方法 |
| CN113754651B (zh) | 2020-06-02 | 2023-04-18 | 中国医学科学院医药生物技术研究所 | 一种β-内酰胺化合物、其用途及其制备方法 |
| JP2024532211A (ja) * | 2021-08-20 | 2024-09-05 | ユニバーシティ・オブ・ノートル・ダム・デュ・ラック | 単環式β－ラクタムとシデロフォア模倣体との結合体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE439312B (sv) * | 1977-03-25 | 1985-06-10 | Roussel Uclaf | Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra |
| NZ205240A (en) * | 1980-02-07 | 1984-07-31 | Squibb & Sons Inc | Sulphonamide derivatives,being starting materials for producing beta-lactams |
| US4252802A (en) * | 1980-03-13 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins |
| EP0048953B1 (de) * | 1980-09-29 | 1988-03-09 | E.R. Squibb & Sons, Inc. | Beta-Lactam-Antibiotika |
| DE3372768D1 (de) * | 1982-06-03 | 1987-09-03 | Hoffmann La Roche | 1-sulfo-2-oxoazetidine derivatives |
-
1984
- 1984-10-09 US US06/658,849 patent/US4610824A/en not_active Expired - Lifetime
-
1985
- 1985-10-08 EP EP85112762A patent/EP0177940B1/de not_active Expired - Lifetime
- 1985-10-08 DE DE8585112762T patent/DE3585980D1/de not_active Expired - Fee Related
- 1985-10-08 AT AT85112762T patent/ATE75743T1/de not_active IP Right Cessation
- 1985-10-08 JP JP60225923A patent/JPH0647588B2/ja not_active Expired - Lifetime
-
1993
- 1993-12-13 JP JP5311610A patent/JPH0755938B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0755938B2 (ja) | 1995-06-14 |
| US4610824A (en) | 1986-09-09 |
| EP0177940A3 (en) | 1988-03-30 |
| EP0177940B1 (de) | 1992-05-06 |
| EP0177940A2 (de) | 1986-04-16 |
| JPS6191187A (ja) | 1986-05-09 |
| JPH0647588B2 (ja) | 1994-06-22 |
| DE3585980D1 (de) | 1992-06-11 |
| JPH06329648A (ja) | 1994-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE75743T1 (de) | Hydrazinderivate und ihre verwendung. | |
| FI914928A0 (fi) | Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner. | |
| NO843642L (no) | Visse nye 1,3-cykloheksandion-derivater med herbicide egenskaper | |
| IT8419790A0 (it) | Derivati pirido-benzotiazinici ad elevata attivita' antimicrobica. | |
| DE3581547D1 (de) | Piperazine-derivate und ihre saeure-additionsalze. | |
| ATE34392T1 (de) | Imidazolinderivate, ihre herstellung und therapeutische verwendung. | |
| AP8800109A0 (en) | "Heterocyclic insecticides". | |
| DK333785A (da) | Mevalonolactonderivater | |
| CA1271748C (en) | BENZAZEPINE DERIVATIVES | |
| IT8422150A0 (it) | Composti dotati di attivita'antiallergica. | |
| EP0175266A3 (en) | Antihypertensive derivatives | |
| ES8602021A1 (es) | Procedimiento de preparar compuestos espirociclicos antihi- pertensivos | |
| ES2093051T3 (es) | Purinil- y pirimidil-tetrahidrofuranos. | |
| IT8523158A0 (it) | Composti eterociclici dotati di attivita' terapeutica. | |
| IT8719846A0 (it) | Composti dotati di attivita'antiallergica. | |
| SU1319521A1 (ru) | 5-(2,2,2-Трифтор-1-окси-1-трифторметилэтил)фурил-2-метилгидразонийбромид, проявляющий антимикробную и противовоспалительную активность | |
| IT8423967A0 (it) | Composti eterociclici dotati di attivita' terapeutica. | |
| SU1351063A1 (ru) | Производные 2-тиазолзамещенного 5-нитрофурана, проявляющие антистафилококковую активность | |
| IT8719845A0 (it) | Composti dotati di attivita'antiallergica. | |
| SU1160709A1 (ru) | Гидрохлорид 6-метил-1-оксо-1,2,3,4-тетрагидроиндоло/2,3-с/-хинолина, обладающий транквилизирующей активностью | |
| SU1610823A1 (ru) | S-трет-бутилтиуронийбромид, обладающий антиишемической активностью | |
| SU1489139A1 (ru) | 3-Изобутил-1-(4-тиоцианатофенил)-5-фенил-Δ-пиразолин, проявляющий противовоспалительную активность | |
| ATE56017T1 (de) | Cephalosporinverbindungen und ihre herstellung. | |
| SU961332A1 (ru) | [5-(2,2-Диметил-4,6-диоксо-1,3-диоксан-5-метенил)фурил-2]-(бензотиазолил-2) сульфид, проявляющий антимикробную активность | |
| SU1262916A1 (ru) | Гидразинопроизводные 1,3-диметил-5-нитрозоурацила, обладающие противомикробной активностью |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |