ATE77627T1 - Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n- formylaminosaeure. - Google Patents

Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n- formylaminosaeure.

Info

Publication number
ATE77627T1
ATE77627T1 AT86830247T AT86830247T ATE77627T1 AT E77627 T1 ATE77627 T1 AT E77627T1 AT 86830247 T AT86830247 T AT 86830247T AT 86830247 T AT86830247 T AT 86830247T AT E77627 T1 ATE77627 T1 AT E77627T1
Authority
AT
Austria
Prior art keywords
formyl
ester
removal
peptide
formylamino acid
Prior art date
Application number
AT86830247T
Other languages
English (en)
Inventor
Goffredo Antonio Bolis
Giuseppe Cantarini
Col Marco Da
Original Assignee
Lark Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lark Spa filed Critical Lark Spa
Application granted granted Critical
Publication of ATE77627T1 publication Critical patent/ATE77627T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/122Hydrolysis with acids different from HF
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT86830247T 1985-09-30 1986-09-05 Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n- formylaminosaeure. ATE77627T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22310/85A IT1190395B (it) 1985-09-30 1985-09-30 Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido
EP86830247A EP0214941B1 (de) 1985-09-30 1986-09-05 Methode für die Beseitigung einer Formylgruppe von einem Ester eines N-Formylpeptids oder von N-Formylaminosäure

Publications (1)

Publication Number Publication Date
ATE77627T1 true ATE77627T1 (de) 1992-07-15

Family

ID=11194494

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86830247T ATE77627T1 (de) 1985-09-30 1986-09-05 Methode fuer die beseitigung einer formylgruppe von einem ester eines n-formylpeptids oder von n- formylaminosaeure.

Country Status (6)

Country Link
US (1) US4851563A (de)
EP (1) EP0214941B1 (de)
AT (1) ATE77627T1 (de)
CA (1) CA1290896C (de)
DE (1) DE3685786T2 (de)
IT (1) IT1190395B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8701035A (nl) * 1987-05-01 1988-12-01 Stamicarbon Werkwijze voor de bereiding van aspartylfenylalaninemethylester uit n-formylaspartylfenylalaninemethylester.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
IT1194795B (it) * 1981-05-13 1988-09-28 Pierrel Spa Procedimento per la eliminazione del gruppo n-formile da peptidi n-formilati e da esteri di peptidi n-formilati
IT1175926B (it) * 1984-01-13 1987-08-12 Debi Derivati Biologici Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenilalanina
IT8422177A0 (it) * 1984-08-01 1984-08-01 Farchemia Spa Procedimento per la preparazione di esteri.

Also Published As

Publication number Publication date
EP0214941B1 (de) 1992-06-24
DE3685786D1 (de) 1992-07-30
CA1290896C (en) 1991-10-15
EP0214941A2 (de) 1987-03-18
IT8522310A0 (it) 1985-09-30
DE3685786T2 (de) 1993-01-21
IT1190395B (it) 1988-02-16
US4851563A (en) 1989-07-25
EP0214941A3 (en) 1989-02-01

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties