ATE77742T1 - Ubidecarenon enthaltende mittel mit erhoehter absorption. - Google Patents

Ubidecarenon enthaltende mittel mit erhoehter absorption.

Info

Publication number: ATE77742T1
Authority: AT; Austria
Prior art keywords: ubidecarenone; increased absorption; containing agents; fatty acid; acid ester
Prior art date: 1985-03-28

Application number

AT86104153T

Other languages

English (en)

Inventor

Yasuhara Saeki

Takeshi Watanabe

Takayuki Ohwaki

Masahiro Kawahara

Yasuo Miyaka

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-28

Filing date

1986-03-26

Publication date

1992-07-15

1986-03-26 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

1992-07-15 Application granted granted Critical

1992-07-15 Publication of ATE77742T1 publication Critical patent/ATE77742T1/de

Links

ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 3
ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 3
235000017471 coenzyme Q10 Nutrition 0.000 title abstract 3
229960004747 ubidecarenone Drugs 0.000 title abstract 3
238000010521 absorption reaction Methods 0.000 title abstract 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
239000000194 fatty acid Substances 0.000 abstract 2
239000007788 liquid Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

AT86104153T 1985-03-28 1986-03-26 Ubidecarenon enthaltende mittel mit erhoehter absorption. ATE77742T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP60061927A JPS61221131A (ja)	1985-03-28	1985-03-28	吸収促進したユビデカレノン含有組成物
EP86104153A EP0196085B1 (de)	1985-03-28	1986-03-26	Ubidecarenon enthaltende Mittel mit erhöhter Absorption

Publications (1)

Publication Number	Publication Date
ATE77742T1 true ATE77742T1 (de)	1992-07-15

Family

ID=13185280

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86104153T ATE77742T1 (de)	1985-03-28	1986-03-26	Ubidecarenon enthaltende mittel mit erhoehter absorption.

Country Status (7)

Country	Link
US (1)	US4827062A (de)
EP (1)	EP0196085B1 (de)
JP (1)	JPS61221131A (de)
AT (1)	ATE77742T1 (de)
CA (1)	CA1266617A (de)
DE (1)	DE3685832T2 (de)
ES (1)	ES8706440A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL87483A (en) *	1987-09-14	1993-07-08	Abbott Lab	Anhydrous oil-based liquid suspension for delivering clorazepate dipotassium or estazolam
US5532002A (en) *	1989-08-17	1996-07-02	Cortecs Limited	Gelatin pharmaceutical formulations
CA2063791C (en) *	1989-08-17	2000-12-19	Michael John Story	Hard gelatine capsule containing fat-soluble nutrients.
US5189066A (en) *	1989-11-22	1993-02-23	The Procter & Gamble Company	Pharmaceutical compositions of tebufelone
US6461593B1 (en) *	1992-02-19	2002-10-08	Biomedical And Clinical Research	Therapy with coenzyme Q10 to reduce subgingival microorganisms in patients with periodontal disease
US5281420A (en) *	1992-05-19	1994-01-25	The Procter & Gamble Company	Solid dispersion compositions of tebufelone
US5559110A (en) *	1994-03-09	1996-09-24	The Dupont Merck Pharmaceutical Company	Pharmaceutical formulations of cyclic urea type compounds
US5447729A (en) *	1994-04-07	1995-09-05	Pharmavene, Inc.	Multilamellar drug delivery systems
GB9705813D0 (en) *	1997-03-20	1997-05-07	Smithkline Beecham Plc	Novel compositions
GB9907715D0 (en) *	1999-04-01	1999-05-26	Scherer Corp R P	Pharmaceutical compositions
DE20122900U1 (de) *	2001-07-12	2009-12-03	Aquanova Ag	Ubichinon Konzentrat
JP2003055204A (ja) *	2001-08-21	2003-02-26	Sansho Iyaku Kk	ユビデカレノン組成物及び同組成物を内容物とするカプセル
US6652891B2 (en) *	2001-12-12	2003-11-25	Herbasway Laboratories, Llc	Co-enzyme Q10 dietary supplement
JP5096658B2 (ja) *	2003-10-06	2012-12-12	株式会社三協	生物学的利用能を向上させたソフトカプセル
JP5258144B2 (ja) *	2004-12-21	2013-08-07	株式会社分子生理化学研究所	吸収性の改善された固形状のコエンザイムｑ１０経口製剤の製造方法
US8574568B2 (en)	2005-11-07	2013-11-05	Kaneka Corporation	Reduced coenzyme Q10-containing composition comprising a surfactant which is stable against oxidation and method for stabilization by mixing with surfactant(s)
JP2009155282A (ja) *	2007-12-27	2009-07-16	Kowa Co	固体分散体含有医薬組成物
EP3110891A4 (de)	2014-02-26	2017-10-11	Elevance Renewable Sciences, Inc.	Zusammensetzungen mit niedrigem gehalt an flüchtigen organischen verbindungen und verfahren zur herstellung und verwendung davon

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE637252A (de) *	1961-09-25
US3452144A (en) *	1966-03-26	1969-06-24	Takeda Chemical Industries Ltd	Method for treatment of congestive heart failure with coenzyme qn
AT360161B (de) *	1977-11-24	1980-12-29	Kali Chemie Pharma Gmbh	Verfahren zur herstellung von enteral hoch- resorbierbaren zubereitungen von an sich schwer resorbierbaren arzneistoffen
JPS5492616A (en) *	1977-12-28	1979-07-23	Ota Pharma	Ubidecalenone soft capsule preparation
JPS5581813A (en) *	1978-12-16	1980-06-20	Nisshin Flour Milling Co Ltd	Composition containing coenzyme q10 and its perparation
JPS5618914A (en) *	1979-07-25	1981-02-23	Eisai Co Ltd	Ubidecarenone composition having good absorbability
CA1208558A (en) *	1982-10-07	1986-07-29	Kazuo Kigasawa	Soft buccal
JPS59148718A (ja) *	1983-02-10	1984-08-25	Fujisawa Pharmaceut Co Ltd	ユビデカレノン組成物
JPS59163316A (ja) *	1983-03-08	1984-09-14	Eisai Co Ltd	けいれんの治療・予防剤
JPS60100517A (ja) *	1983-11-08	1985-06-04	Eisai Co Ltd	放射線潰瘍治療剤および方法

1985
- 1985-03-28 JP JP60061927A patent/JPS61221131A/ja active Pending
1986
- 1986-03-25 US US06/844,025 patent/US4827062A/en not_active Expired - Fee Related
- 1986-03-26 AT AT86104153T patent/ATE77742T1/de not_active IP Right Cessation
- 1986-03-26 CA CA000505220A patent/CA1266617A/en not_active Expired - Fee Related
- 1986-03-26 ES ES553499A patent/ES8706440A1/es not_active Expired
- 1986-03-26 EP EP86104153A patent/EP0196085B1/de not_active Expired - Lifetime
- 1986-03-26 DE DE8686104153T patent/DE3685832T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US4827062A (en)	1989-05-02
DE3685832T2 (de)	1992-12-17
EP0196085A2 (de)	1986-10-01
ES553499A0 (es)	1987-06-16
CA1266617A (en)	1990-03-13
JPS61221131A (ja)	1986-10-01
EP0196085A3 (en)	1987-08-12
EP0196085B1 (de)	1992-07-01
ES8706440A1 (es)	1987-06-16
DE3685832D1 (de)	1992-08-06

Legal Events

Date	Code	Title	Description
1993-02-15	UEP	Publication of translation of european patent specification
2001-12-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3685832D1 (de)	1992-08-06	Ubidecarenon enthaltende mittel mit erhoehter absorption.
DK581185D0 (da)	1985-12-13	Farmaceutisk praeparat indeholdende 13-cis-a-vitaminsyre
DE3669882D1 (de)	1990-05-03	2-zyanakrylsaeureester enthaltende zusammensetzung.
FI872438A7 (fi)	1987-06-01	Lipidimolekyylejä sisältävät koostumukset, joilla on lisääntynyt angi ogeeninen aktiivisuus.
ES2059775T3 (es)	1994-11-16	Composicion que contiene morfina.
IE830114L (en)	1983-07-21	Propylene glycol diester solutions of pge-type compounds
NO904196L (no)	1991-04-02	Orale preparater som virker mot plaque.
FI844677A0 (fi)	1984-11-28	Komposition och metod foer snabb upptaeckt av mikroorganismer i kliniska prover.
NO890271D0 (no)	1989-01-20	Steroid-lotion.
MX9203126A (es)	1992-07-01	Derivados de sulfonilurea y composiciones farmaceuticas que los contienen.
IL92357A0 (en)	1990-07-26	Pharmaceutical compositions containing an antibacterial compound and an absorption enhancing system
FI854167A0 (fi)	1985-10-24	Mun- och tandvaordsmedel.
NO862587D0 (no)	1986-06-26	Fremgangsmaate for fremstilling av en injiserbar opploesning inneholdende et antitumorantracyklin-glykosid.
DK0487973T3 (da)	1996-07-29	Topisk lotion indeholdende niclosamid
ATE75583T1 (de)	1992-05-15	Nicarbazin enthaltende vormischungszusammensetzungen.
TR27070A (tr)	1994-10-12	Stabilize edici maddeler ihtiva eden temizleme gücü artirilmis deterjan bilesimleri.
DE69017969D1 (de)	1995-04-27	2-Cyclohexylpropionsäure oder Derivate davon enthaltende Riechstoffzusammensetzung.
DE3688407D1 (de)	1993-06-17	Covulkanisierbare zusammensetzungen von fluorelastomeren.
FI854441A0 (fi)	1985-11-12	Foerfarande foer framstaellning av natriumperkarbonat i granulatform.
ATE36718T1 (de)	1988-09-15	Glykosaminoglykane verwendbar in kosmetologie.
DE3761662D1 (de)	1990-03-15	Dihydropyridin-5-phosphonsaure zyklische propylenester.
ATE33552T1 (de)	1988-05-15	Dermatologische praeparate.
SE9004076D0 (sv)	1990-12-20	Anvaendning av 10-acetyl-1,8,9-triacetoxi-antracen som antiinflammatoriskst medel vid framstaellning av farmaceutiska och kosmetiska kompositioner
UA13708A1 (uk)	1997-04-25	Кріопротектор
IT8223491A0 (it)	1982-09-28	Composizioni poliimidiche stabili all'ossidazione.