ATE78822T1 - Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung. - Google Patents

Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.

Info

Publication number: ATE78822T1
Authority: AT; Austria
Prior art keywords: sup; quinolizine; hydrates; benzo; salts
Prior art date: 1985-05-24

Application number

AT86303948T

Other languages

English (en)

Inventor

Atsushi Takagi

Masao Yajima

Toshiaki Kikuchi

Masaki Saeki

Original Assignee

Tokyo Tanabe Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-24

Filing date

1986-05-23

Publication date

1992-08-15

1986-05-23 Application filed by Tokyo Tanabe Co filed Critical Tokyo Tanabe Co

1992-08-15 Application granted granted Critical

1992-08-15 Publication of ATE78822T1 publication Critical patent/ATE78822T1/de

Links

150000004677 hydrates Chemical class 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
229910052799 carbon Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
230000005923 long-lasting effect Effects 0.000 abstract 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)

AT86303948T 1985-05-24 1986-05-23 Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung. ATE78822T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP11022785		1985-05-24
JP11022685		1985-05-24
EP86303948A EP0203795B1 (de)	1985-05-24	1986-05-23	Benzo[i,j]chinolizin-2-carbonsäurederivate, ihre Salze und Hydrate, diese enthaltende pharmazeutische Zubereitungen und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number	Publication Date
ATE78822T1 true ATE78822T1 (de)	1992-08-15

Family

ID=26449894

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86303948T ATE78822T1 (de)	1985-05-24	1986-05-23	Benzo(i,j>chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.

Country Status (6)

Country	Link
US (1)	US4720495A (de)
EP (1)	EP0203795B1 (de)
AT (1)	ATE78822T1 (de)
AU (1)	AU585981B2 (de)
CA (1)	CA1253154A (de)
DE (1)	DE3686201T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4929613A (en) *	1987-08-26	1990-05-29	Warner-Lambert Company	Antibacterial agents
JPH01250380A (ja) *	1987-12-26	1989-10-05	Tokyo Tanabe Co Ltd	光学活性ベンゾキノリジン誘導体、その製造方法およびそれを有効成分とする抗菌剤
NZ232091A (en) *	1989-01-16	1990-12-21	Bellon Labor Sa Roger	7-fluoro-8-(piperazin-1-yl)-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof
US4923868A (en) *	1989-02-21	1990-05-08	American Cyanamid Company	8-fluoro and 7,8,10-trifluoro-9-(substituted)-6-oxo-6H-benzo(C)quinolizine-5-carboxylic acids
US4948894A (en) *	1989-02-21	1990-08-14	American Cyanamid Company	8-fluoro and 7, 8, 10-trifluoro-9-(substituted)-6-oxo-6H-benzo-(C)quinolizine-5-carboxylic acids

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4014877A (en) *	1972-11-02	1977-03-29	Riker Laboratories, Inc.	Substituted benzo[ij]quinolizine-2-carboxylic acids and derivatives thereof
JPS5040616A (de) *	1973-07-06	1975-04-14
ES446538A1 (es) *	1975-04-14	1977-10-16	Riker Laboratories Inc	Procedimiento para preparar benzoquinoliznios sustituidos.
JPS6019910B2 (ja) *	1979-10-11	1985-05-18	大塚製薬株式会社	ベンゾ〔ｉｊ〕キノリジン−２−カルボン酸誘導体及びその製造法
DE2953974C2 (de) *	1978-04-12	1992-06-25	Otsuka Pharmaceutical Co., Ltd., Tokio/Tokyo, Jp
US4416884A (en) *	1978-04-12	1983-11-22	Otsuka Pharmaceutical Co., Ltd.	Piperazinylbenzoheterocyclic compounds
JPS5746986A (en) *	1980-09-02	1982-03-17	Dai Ichi Seiyaku Co Ltd	Pyrido(1,2,3-de)(1,4)benzoxazine derivative
NO156828C (no) *	1980-11-10	1987-12-02	Otsuka Pharma Co Ltd	Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
AT380250B (de) *	1980-12-18	1986-04-25	Otsuka Pharma Co Ltd	Verfahren zur herstellung benzoheterocyclischer verbindungen
JPS59106488A (ja) *	1982-12-10	1984-06-20	Dai Ichi Seiyaku Co Ltd	ベンゾキノリジン誘導体
JPS59137482A (ja) *	1983-01-26	1984-08-07	Otsuka Pharmaceut Co Ltd	ピロロ〔３，２，１，−ｉｊ〕キノリン−５−カルボン酸誘導体
US4659734A (en) *	1983-08-15	1987-04-21	Nippon Shinyaku Co., Ltd.	Olinecarboxylic acid derivatives

1986
- 1986-05-15 CA CA000509221A patent/CA1253154A/en not_active Expired
- 1986-05-15 AU AU57484/86A patent/AU585981B2/en not_active Ceased
- 1986-05-20 US US06/865,530 patent/US4720495A/en not_active Expired - Fee Related
- 1986-05-23 EP EP86303948A patent/EP0203795B1/de not_active Expired - Lifetime
- 1986-05-23 AT AT86303948T patent/ATE78822T1/de not_active IP Right Cessation
- 1986-05-23 DE DE8686303948T patent/DE3686201T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU585981B2 (en)	1989-06-29
DE3686201T2 (de)	1993-01-07
AU5748486A (en)	1986-11-27
EP0203795A2 (de)	1986-12-03
EP0203795A3 (en)	1988-02-10
DE3686201D1 (de)	1992-09-03
US4720495A (en)	1988-01-19
EP0203795B1 (de)	1992-07-29
CA1253154A (en)	1989-04-25

Similar Documents

Publication	Publication Date	Title
ATE60761T1 (de)	1991-02-15	Chinazolinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE22889T1 (de)	1986-11-15	8-chlor-1,5-benzothiazepinderivate, verfahren zur herstellung und pharmazeutische zusammensetzungen.
DE3576690D1 (de)	1990-04-26	Pyrimidopyrimidinderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als anti-allergische mittel.
ATE13056T1 (de)	1985-05-15	Indanderivate, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
NO810478L (no)	1981-08-14	Fremgangsmaate for fremstilling av terapeutisk aktive substituerte imidazolderivater
DE69004340D1 (de)	1993-12-09	Substituierte 2-Alkinylphenole mit entzündungshemmender Wirkung, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen.
ATE40126T1 (de)	1989-02-15	1,5-benzothiazepinderivate, verfahren zu ihrer herstellung und arzneimittel.
NO158017C (no)	1988-06-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolderivater.
MY101801A (en)	1992-01-31	Novel phenoxyacetic acid derivatives, process for preparing the same and pharmaceutical composition having the same as an active ingredient.
ATE41772T1 (de)	1989-04-15	Polymethoxybenzyl-piperazin-derivate, verfahren zu ihrer herstellung und diese derivate enthaltende pharmazeutische zusammensetzungen.
PL109657B1 (en)	1980-06-30	Method of producing new derivatives of pyrido/1,2a/pyrimidine
DE3686201D1 (de)	1992-09-03	Benzo(i,j)chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.
ATE40127T1 (de)	1989-02-15	1,5-benzothiazepinderivate, verfahren zu ihrer herstellung und arzneimittel.
ATE48994T1 (de)	1990-01-15	Benzimidazol-derivat, verfahren zu seiner herstellung und pharmazeutische zusammensetzung.
CA2128202A1 (en)	1993-07-22	Alkyl Derivatives of Trazodone with CNS Activity
EP0299076A4 (en)	1991-01-09	5-hydroxyindole-3-carboxamide compound and medicinal use thereof
ATE34739T1 (de)	1988-06-15	Neue 2-pyridin-thiol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
IE781467L (en)	1979-01-25	4"-ureido-oleandomycin derivatives
ATE63114T1 (de)	1991-05-15	Piperazinderivate, verfahren zu ihrer herstellung und diese als wirkstoffe enthaltende pharmazeutische zusammensetzungen.
ATE52509T1 (de)	1990-05-15	Thiazolidinderivate und verfahren zu ihrer herstellung.
JPS56150017A (en)	1981-11-20	Cholesteril lowering agent
JPS57139015A (en)	1982-08-27	Remedy for infectious disease for oral administration
JPS5566560A (en)	1980-05-20	Quinolone derivative
ES8308565A1 (es)	1983-09-01	Procedimiento para la preparacion de compuestos de 1,4-benzodiazepina.
JPS5615291A (en)	1981-02-14	Oxacephamycin derivative, its preparation, and antibacterial agent consisting mainly of it

Legal Events

Date	Code	Title	Description
1993-02-15	UEP	Publication of translation of european patent specification
1999-02-15	REN	Ceased due to non-payment of the annual fee