ATE79276T1 - Pasteurisierung von immunoglobulinloesungen. - Google Patents

Pasteurisierung von immunoglobulinloesungen.

Info

Publication number
ATE79276T1
ATE79276T1 AT87310326T AT87310326T ATE79276T1 AT E79276 T1 ATE79276 T1 AT E79276T1 AT 87310326 T AT87310326 T AT 87310326T AT 87310326 T AT87310326 T AT 87310326T AT E79276 T1 ATE79276 T1 AT E79276T1
Authority
AT
Austria
Prior art keywords
pasteurization
immunoglobulin solutions
mildly
immunoglobulin
solutions
Prior art date
Application number
AT87310326T
Other languages
English (en)
Inventor
Anthony A Magnin
Po-Shing Wah
Paul Dennis
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Lab filed Critical Connaught Lab
Application granted granted Critical
Publication of ATE79276T1 publication Critical patent/ATE79276T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/04—Heat
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/861—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgG3, IgG4, IgA, or IgY

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT87310326T 1986-11-25 1987-11-23 Pasteurisierung von immunoglobulinloesungen. ATE79276T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868628104A GB8628104D0 (en) 1986-11-25 1986-11-25 Pasteurization of immunoglobin solutions
EP87310326A EP0269405B1 (de) 1986-11-25 1987-11-23 Pasteurisierung von Immunoglobulinlösungen

Publications (1)

Publication Number Publication Date
ATE79276T1 true ATE79276T1 (de) 1992-08-15

Family

ID=10607869

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87310326T ATE79276T1 (de) 1986-11-25 1987-11-23 Pasteurisierung von immunoglobulinloesungen.

Country Status (16)

Country Link
US (1) US4849508A (de)
EP (1) EP0269405B1 (de)
JP (1) JPS6485929A (de)
KR (1) KR900006889B1 (de)
CN (1) CN1020253C (de)
AT (1) ATE79276T1 (de)
AU (1) AU596714B2 (de)
BR (1) BR8706374A (de)
CA (1) CA1302884C (de)
DE (1) DE3781104T2 (de)
ES (1) ES2033880T3 (de)
GB (1) GB8628104D0 (de)
GR (1) GR3005451T3 (de)
MX (1) MX168854B (de)
RU (1) RU2008916C1 (de)
ZA (1) ZA878815B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165467A (en) * 1991-07-20 2000-12-26 Yoshihide Hagiwara Stabilized human monoclonal antibody preparation
JPH07126182A (ja) * 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
FI952196A0 (fi) * 1995-05-08 1995-05-08 Suomen Punainen Risti Veripalv Framstaellning av immunoglobulin
US6686191B1 (en) * 1995-09-22 2004-02-03 Bayer Healthcare Llc Preparation of virally inactivated intravenously injectable immune serum globulin
KR20000067911A (ko) * 1996-07-18 2000-11-25 씨에스엘 리미티드 면역글로불린 용액의 저온살균방법
TW491855B (en) * 1996-08-07 2002-06-21 Csl Ltd Purification of immunoglobulins
CN1137727C (zh) * 1998-06-25 2004-02-11 四川远大蜀阳药业有限公司 无保护剂双重病毒灭活制备静注免疫球蛋白工艺
PT2193809E (pt) 1999-02-22 2015-08-24 Baxter Int Formulações de fator viii livres de albumina
WO2001055354A1 (en) * 2000-01-31 2001-08-02 Consortium For Plasma Science, Llc Methods for inactivating viruses
US7863011B2 (en) * 2000-05-10 2011-01-04 Signe Biopharma, Inc. Screening method for predicting susceptibility to breast cancer
US8119138B2 (en) * 2000-05-10 2012-02-21 Signe Biopharma Inc. Anti-estrogen and immune modulator combinations for treating breast cancer
US7947275B2 (en) 2000-05-10 2011-05-24 Signe Biopharma, Inc. Compositions and methods for demonstrating secretory immune system regulation of steroid hormone responsive cancer cell growth
GB0113179D0 (en) 2001-05-31 2001-07-25 Novartis Ag Organic compounds
EP1532983A1 (de) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulinpräparationen mit erhöhter Stabilität
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
ES2776657T3 (es) 2005-06-14 2020-07-31 Amgen Inc Formulaciones de proteínas autotamponantes
BRPI0719250A2 (pt) * 2006-10-12 2015-06-16 Wyeth Corp Métodos e composições com opalescência reduzida.
US8475789B2 (en) 2008-01-22 2013-07-02 Multimerics Aps Products and methods to prevent infections
BRPI0921429B1 (pt) * 2008-11-07 2022-07-12 Takeda Pharmaceutical Company Limited Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável
CA2788863C (en) 2010-02-04 2020-07-07 Csl Behring Ag Immunoglobulin preparation
EP2361636A1 (de) 2010-02-26 2011-08-31 CSL Behring AG Immunglobulinpräparat und Aufbewahrungssystem für ein Immunglobulinpräparat
MX388043B (es) 2014-12-03 2025-03-19 Csl Behring Ag Producto farmacéutico con estabilidad incrementada que comprende inmunoglobulinas.
EP3528787B1 (de) 2016-10-21 2026-01-07 Amgen Inc. Pharmazeutische formulierungen und verfahren zur herstellung davon

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3930039A (en) * 1971-07-30 1975-12-30 Molkerei J A Meggle Milchindus Method of preparing a protein concentrate from whey
US3896241A (en) * 1971-09-01 1975-07-22 Coca Cola Co Preparation of a whey protein concentrate
US3986927A (en) * 1975-04-28 1976-10-19 Armour Pharmaceutical Company Process for the purification and sterilization of acidophilic biologicals by extreme acidification at cold temperatures
DE2527064C3 (de) * 1975-06-18 1979-11-15 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines intravenösen Nativ-Human-Immunglobulin-Präparates mit natürlicher Halbwertszeit und gegenüber dem Ausgangsmaterial unveränderten Antikörperaktivität
NL7708005A (nl) * 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
US4075197A (en) * 1976-09-20 1978-02-21 Monsanto Company Serum albumin production
CH630243A5 (fr) * 1978-05-11 1982-06-15 Nestle Sa Procede de recuperation des proteines du lactoserum.
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4623717A (en) * 1980-03-05 1986-11-18 Miles Laboratories, Inc. Pasteurized therapeutically active protein compositions
JPS57140724A (en) * 1981-02-25 1982-08-31 Green Cross Corp:The Heat-treatment of aqueous solution containing cold insoluble globulin
JPS5874617A (ja) * 1981-10-28 1983-05-06 Green Cross Corp:The 人由来血液凝固第７因子含有水溶液の加熱処理方法
EP0124506B1 (de) * 1983-05-02 1988-08-17 IMMUNO Aktiengesellschaft für chemisch-medizinische Produkte Verfahren zur Inaktivierung von vermehrungsfähigen Krankheitserregern
JPH0669961B2 (ja) * 1984-09-25 1994-09-07 株式会社ミドリ十字 免疫グロブリンの加熱処理方法
JPH0825902B2 (ja) * 1985-02-21 1996-03-13 株式会社ミドリ十字 γ−グロブリンの加熱処理方法
DK595285D0 (da) * 1985-12-20 1985-12-20 Nordisk Gentofte Injicerbart og varmebehandet igg-praeparat og fremgangsmaade til fremstilling af samme
EP0445108A1 (de) * 1986-03-10 1991-09-11 RUBINSTEIN, Alan I. Verfahren zur behandlung von gammaglobulin

Also Published As

Publication number Publication date
KR900006889B1 (ko) 1990-09-24
RU2008916C1 (ru) 1994-03-15
EP0269405B1 (de) 1992-08-12
DE3781104T2 (de) 1992-12-17
AU596714B2 (en) 1990-05-10
GR3005451T3 (de) 1993-05-24
US4849508A (en) 1989-07-18
EP0269405A3 (en) 1989-05-10
CN87101294A (zh) 1988-07-06
MX168854B (es) 1993-06-11
DE3781104D1 (de) 1992-09-17
CN1020253C (zh) 1993-04-14
KR880005938A (ko) 1988-07-21
CA1302884C (en) 1992-06-09
ZA878815B (en) 1988-05-24
GB8628104D0 (en) 1986-12-31
JPH0438730B2 (de) 1992-06-25
ES2033880T3 (es) 1993-04-01
JPS6485929A (en) 1989-03-30
EP0269405A2 (de) 1988-06-01
BR8706374A (pt) 1988-07-19
AU8168187A (en) 1988-05-26

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time