ATE81009T1 - N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel. - Google Patents

N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.

Info

Publication number: ATE81009T1
Authority: AT; Austria
Prior art keywords: acetyl; fluoroneuraminic; acid; antiviral medicine; fluoroneuraminic acid
Prior art date: 1988-05-13

Application number

AT89108596T

Other languages

English (en)

Inventor

Isao Suda

Hiroshi Ohrui

Hiroshi Meguro

Tatsuo Ido

Original Assignee

Kanto Ishi Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-13

Filing date

1989-05-12

Publication date

1992-10-15

1989-05-12 Application filed by Kanto Ishi Pharma Co Ltd filed Critical Kanto Ishi Pharma Co Ltd

1992-10-15 Application granted granted Critical

1992-10-15 Publication of ATE81009T1 publication Critical patent/ATE81009T1/de

Links

ALJLGESFXXDPKH-OLUMBMSPSA-N (4R,5R,6R)-5-acetamido-3-fluoro-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C(F)C(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ALJLGESFXXDPKH-OLUMBMSPSA-N 0.000 title abstract 2
230000000840 anti-viral effect Effects 0.000 title 1
239000003443 antiviral agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT89108596T 1988-05-13 1989-05-12 N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel. ATE81009T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP63116500A JPH01287029A (ja)	1988-05-13	1988-05-13	新規抗ウィルス剤
EP89108596A EP0341735B1 (de)	1988-05-13	1989-05-12	N-acetyl-3-fluoroneuraminsäure als antivirales Arzneimittel

Publications (1)

Publication Number	Publication Date
ATE81009T1 true ATE81009T1 (de)	1992-10-15

Family

ID=14688671

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89108596T ATE81009T1 (de)	1988-05-13	1989-05-12	N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.

Country Status (9)

Country	Link
EP (1)	EP0341735B1 (de)
JP (1)	JPH01287029A (de)
KR (1)	KR970005326B1 (de)
AT (1)	ATE81009T1 (de)
AU (1)	AU624138B2 (de)
DE (1)	DE68903031T2 (de)
DK (1)	DK232989A (de)
IL (1)	IL90271A (de)
NZ (1)	NZ229128A (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992006691A1 (en) *	1990-10-19	1992-04-30	Biota Scientific Management Pty. Ltd.	Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
GB9410817D0 (en) *	1994-05-28	1994-07-20	Glaxo Group Ltd	Medicaments
US7960139B2 (en)	2007-03-23	2011-06-14	Academia Sinica	Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
ES2442024T3 (es)	2008-07-15	2014-02-07	Academia Sinica	Matrices de glucano sobre portaobjetos de vidrio revestidos con aluminio de tipo PTFE y métodos relacionados
US11377485B2 (en)	2009-12-02	2022-07-05	Academia Sinica	Methods for modifying human antibodies by glycan engineering
US10087236B2 (en)	2009-12-02	2018-10-02	Academia Sinica	Methods for modifying human antibodies by glycan engineering
US10338069B2 (en)	2010-04-12	2019-07-02	Academia Sinica	Glycan arrays for high throughput screening of viruses
US10130714B2 (en)	2012-04-14	2018-11-20	Academia Sinica	Enhanced anti-influenza agents conjugated with anti-inflammatory activity
WO2014031498A1 (en) *	2012-08-18	2014-02-27	Academia Sinica	Cell-permeable probes for identification and imaging of sialidases
EP3013365B1 (de)	2013-06-26	2019-06-05	Academia Sinica	Rm2-antigene und verwendung davon
EP3013347B1 (de)	2013-06-27	2019-12-11	Academia Sinica	Glykankonjugate und verwendung davon
JP6486368B2 (ja)	2013-09-06	2019-03-20	アカデミアシニカＡｃａｄｅｍｉａＳｉｎｉｃａ	改変されたグリコシル基を含む糖脂質を用いたヒトｉＮＫＴ細胞の活性化
AU2015206370A1 (en)	2014-01-16	2016-07-07	Academia Sinica	Compositions and methods for treatment and detection of cancers
US10150818B2 (en)	2014-01-16	2018-12-11	Academia Sinica	Compositions and methods for treatment and detection of cancers
CN106415244B (zh)	2014-03-27	2020-04-24	中央研究院	反应性标记化合物及其用途
CA2950415A1 (en)	2014-05-27	2015-12-03	Academia Sinica	Anti-cd20 glycoantibodies and uses thereof
JP7093612B2 (ja)	2014-05-27	2022-06-30	アカデミアシニカ	Ｂａｃｔｅｒｏｉｄｅｓ由来のフコシダーゼおよびそれを使用する方法
CN106661099A (zh)	2014-05-27	2017-05-10	中央研究院	抗her2醣抗体及其用途
US10118969B2 (en)	2014-05-27	2018-11-06	Academia Sinica	Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
WO2015184001A1 (en)	2014-05-28	2015-12-03	Academia Sinica	Anti-tnf-alpha glycoantibodies and uses thereof
TWI745275B (zh)	2014-09-08	2021-11-11	中央研究院	使用醣脂激活人類ｉＮＫＴ細胞
US9975965B2 (en)	2015-01-16	2018-05-22	Academia Sinica	Compositions and methods for treatment and detection of cancers
US10495645B2 (en)	2015-01-16	2019-12-03	Academia Sinica	Cancer markers and methods of use thereof
JP6779887B2 (ja)	2015-01-24	2020-11-04	アカデミアシニカＡｃａｄｅｍｉａＳｉｎｉｃａ	新規なグリカンコンジュゲートおよびその使用方法
EP3426693A4 (de)	2016-03-08	2019-11-13	Academia Sinica	Verfahren zur modularen synthese von n-glykanen und anordnungen davon
CA3034057A1 (en)	2016-08-22	2018-03-01	CHO Pharma Inc.	Antibodies, binding fragments, and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2573594B2 (ja) *	1987-03-06	1997-01-22	メクト株式会社	Ｎーアセチルー３ーフルオローノイラミン酸誘導体およびその製造方法

1988
- 1988-05-13 JP JP63116500A patent/JPH01287029A/ja active Pending
1989
- 1989-05-12 AT AT89108596T patent/ATE81009T1/de not_active IP Right Cessation
- 1989-05-12 DE DE8989108596T patent/DE68903031T2/de not_active Expired - Fee Related
- 1989-05-12 AU AU34798/89A patent/AU624138B2/en not_active Ceased
- 1989-05-12 DK DK232989A patent/DK232989A/da not_active Application Discontinuation
- 1989-05-12 IL IL9027189A patent/IL90271A/en unknown
- 1989-05-12 EP EP89108596A patent/EP0341735B1/de not_active Expired - Lifetime
- 1989-05-13 KR KR1019890006392A patent/KR970005326B1/ko not_active Expired - Lifetime
- 1989-05-15 NZ NZ229128A patent/NZ229128A/en unknown

Also Published As

Publication number	Publication date
DE68903031T2 (de)	1993-02-18
IL90271A (en)	1994-04-12
EP0341735A1 (de)	1989-11-15
KR970005326B1 (ko)	1997-04-15
DK232989A (da)	1989-11-14
NZ229128A (en)	1991-05-28
AU3479889A (en)	1989-11-16
KR890016966A (ko)	1989-12-14
AU624138B2 (en)	1992-06-04
JPH01287029A (ja)	1989-11-17
EP0341735B1 (de)	1992-09-30
DK232989D0 (da)	1989-05-12
DE68903031D1 (de)	1992-11-05
IL90271A0 (en)	1989-12-15

Legal Events

Date	Code	Title	Description
1993-04-15	UEP	Publication of translation of european patent specification
1996-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE81009T1 (de)	1992-10-15	N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.
FI914928A0 (fi)	1991-10-18	Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
SE8505112D0 (sv)	1985-10-29	Novel pharmacological compounds
AU666702B2 (en)	1996-02-22	Morphinan derivative and medicinal use
DE59010810D1 (de)	1998-04-16	Arzneimittel enthaltend als Wirkstoff R-alpha-Liponsäure oder S-alpha-Liponsäure
ATE143598T1 (de)	1996-10-15	Arzneimittellösung enhaltend derivate von fk506
ATE110071T1 (de)	1994-09-15	Pyridazinon-derivate und diese enthaltende pharmazeutische zubereitungen.
DE68919378D1 (de)	1994-12-22	Thienotriazolodiazepine und ihre pharmazeutische Verwendung.
DK0571243T3 (da)	1995-12-04	Thiochromanderivater, fremgangsmåder til fremstilling heraf samt farmaceutiske midler indeholdende d isse
DE69627519D1 (de)	2003-05-22	Sesquiterpen-derivate mit antiviraler aktivität
AU621634B2 (en)	1992-03-19	Glycerin derivative and its pharmacological use
DK540589A (da)	1990-05-01	Pyrrolidinderivater
ES2093051T3 (es)	1996-12-16	Purinil- y pirimidil-tetrahidrofuranos.
DK0580503T3 (da)	1995-11-06	Aminoalkylchromoner, fremgangsmåde til fremstilling heraf samt midler indeholdende disse
ATE57928T1 (de)	1990-11-15	1-alkyl-ergolinyl-thioharnstoffderivate.
ATE89288T1 (de)	1993-05-15	L-pyroglutamyl-l-cystein-dipeptid mit hoher anti- cataractogener wirkung und dies enthaltende pharmazeutische zusammensetzungen.