ATE81009T1 - N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel. - Google Patents

N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.

Info

Publication number: ATE81009T1
Authority: AT; Austria
Prior art keywords: acetyl; fluoroneuraminic; acid; antiviral medicine; fluoroneuraminic acid
Prior art date: 1988-05-13

Application number

AT89108596T

Other languages

English (en)

Inventor

Isao Suda

Hiroshi Ohrui

Hiroshi Meguro

Tatsuo Ido

Original Assignee

Kanto Ishi Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-13

Filing date

1989-05-12

Publication date

1992-10-15

1989-05-12 Application filed by Kanto Ishi Pharma Co Ltd filed Critical Kanto Ishi Pharma Co Ltd

1992-10-15 Application granted granted Critical

1992-10-15 Publication of ATE81009T1 publication Critical patent/ATE81009T1/de

Links

ALJLGESFXXDPKH-OLUMBMSPSA-N (4R,5R,6R)-5-acetamido-3-fluoro-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C(F)C(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ALJLGESFXXDPKH-OLUMBMSPSA-N 0.000 title abstract 2
230000000840 anti-viral effect Effects 0.000 title 1
239000003443 antiviral agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT89108596T 1988-05-13 1989-05-12 N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel. ATE81009T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP63116500A JPH01287029A (ja)	1988-05-13	1988-05-13	新規抗ウィルス剤
EP89108596A EP0341735B1 (de)	1988-05-13	1989-05-12	N-acetyl-3-fluoroneuraminsäure als antivirales Arzneimittel

Publications (1)

Publication Number	Publication Date
ATE81009T1 true ATE81009T1 (de)	1992-10-15

Family

ID=14688671

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT89108596T ATE81009T1 (de)	1988-05-13	1989-05-12	N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.

Country Status (9)

Country	Link
EP (1)	EP0341735B1 (de)
JP (1)	JPH01287029A (de)
KR (1)	KR970005326B1 (de)
AT (1)	ATE81009T1 (de)
AU (1)	AU624138B2 (de)
DE (1)	DE68903031T2 (de)
DK (1)	DK232989A (de)
IL (1)	IL90271A (de)
NZ (1)	NZ229128A (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992006691A1 (en) *	1990-10-19	1992-04-30	Biota Scientific Management Pty. Ltd.	Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
GB9410817D0 (en) *	1994-05-28	1994-07-20	Glaxo Group Ltd	Medicaments
US7960139B2 (en)	2007-03-23	2011-06-14	Academia Sinica	Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
DK2318832T3 (da)	2008-07-15	2014-01-20	Academia Sinica	Glycan-arrays på PTFE-lignende aluminiumcoatede objektglas og relaterede fremgangsmåder
US11377485B2 (en)	2009-12-02	2022-07-05	Academia Sinica	Methods for modifying human antibodies by glycan engineering
US10087236B2 (en)	2009-12-02	2018-10-02	Academia Sinica	Methods for modifying human antibodies by glycan engineering
WO2011130332A1 (en)	2010-04-12	2011-10-20	Academia Sinica	Glycan arrays for high throughput screening of viruses
US10130714B2 (en)	2012-04-14	2018-11-20	Academia Sinica	Enhanced anti-influenza agents conjugated with anti-inflammatory activity
US9914956B2 (en) *	2012-08-18	2018-03-13	Academia Sinica	Cell-permeable probes for identification and imaging of sialidases
WO2014210397A1 (en)	2013-06-26	2014-12-31	Academia Sinica	Rm2 antigens and use thereof
EP3013347B1 (de)	2013-06-27	2019-12-11	Academia Sinica	Glykankonjugate und verwendung davon
EP3041484B1 (de)	2013-09-06	2021-03-03	Academia Sinica	Humane inkt-zell-aktivierung mittels glykolipiden mit veränderten glycosylgruppen
US10150818B2 (en)	2014-01-16	2018-12-11	Academia Sinica	Compositions and methods for treatment and detection of cancers
KR20160104727A (ko)	2014-01-16	2016-09-05	아카데미아 시니카	암의 치료 및 검출을 위한 조성물 및 방법
TWI797430B (zh)	2014-03-27	2023-04-01	中央研究院	反應性標記化合物及其用途
US10118969B2 (en)	2014-05-27	2018-11-06	Academia Sinica	Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
KR20170010003A (ko)	2014-05-27	2017-01-25	아카데미아 시니카	박테로이드 기원의 푸코시다제 및 이의 사용 방법
JP2017518989A (ja)	2014-05-27	2017-07-13	アカデミアシニカＡｃａｄｅｍｉａＳｉｎｉｃａ	抗ｃｄ２０糖操作抗体群およびその使用
EP4116329A1 (de)	2014-05-27	2023-01-11	Academia Sinica	Anti-her2-glykoantikörper und verwendungen davon
JP7063538B2 (ja)	2014-05-28	2022-05-09	アカデミアシニカ	抗ＴＮＦα糖操作抗体群およびその使用
EP3191500A4 (de)	2014-09-08	2018-04-11	Academia Sinica	Aktivierung menschlicher inkt-zellen mithilfe von glykolipiden
US9975965B2 (en)	2015-01-16	2018-05-22	Academia Sinica	Compositions and methods for treatment and detection of cancers
US10495645B2 (en)	2015-01-16	2019-12-03	Academia Sinica	Cancer markers and methods of use thereof
AU2015378564A1 (en)	2015-01-24	2017-07-13	Academia Sinica	Novel glycan conjugates and methods of use thereof
CN109195996A (zh)	2016-03-08	2019-01-11	中央研究院	N-聚醣及其阵列的模组化合成方法
CA3034057A1 (en)	2016-08-22	2018-03-01	CHO Pharma Inc.	Antibodies, binding fragments, and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2573594B2 (ja) *	1987-03-06	1997-01-22	メクト株式会社	Ｎーアセチルー３ーフルオローノイラミン酸誘導体およびその製造方法

1988
- 1988-05-13 JP JP63116500A patent/JPH01287029A/ja active Pending
1989
- 1989-05-12 IL IL9027189A patent/IL90271A/en unknown
- 1989-05-12 AU AU34798/89A patent/AU624138B2/en not_active Ceased
- 1989-05-12 AT AT89108596T patent/ATE81009T1/de not_active IP Right Cessation
- 1989-05-12 DE DE8989108596T patent/DE68903031T2/de not_active Expired - Fee Related
- 1989-05-12 DK DK232989A patent/DK232989A/da not_active Application Discontinuation
- 1989-05-12 EP EP89108596A patent/EP0341735B1/de not_active Expired - Lifetime
- 1989-05-13 KR KR1019890006392A patent/KR970005326B1/ko not_active Expired - Lifetime
- 1989-05-15 NZ NZ229128A patent/NZ229128A/en unknown

Also Published As

Publication number	Publication date
DE68903031T2 (de)	1993-02-18
JPH01287029A (ja)	1989-11-17
IL90271A (en)	1994-04-12
AU624138B2 (en)	1992-06-04
KR970005326B1 (ko)	1997-04-15
EP0341735B1 (de)	1992-09-30
IL90271A0 (en)	1989-12-15
DE68903031D1 (de)	1992-11-05
AU3479889A (en)	1989-11-16
EP0341735A1 (de)	1989-11-15
DK232989A (da)	1989-11-14
NZ229128A (en)	1991-05-28
DK232989D0 (da)	1989-05-12
KR890016966A (ko)	1989-12-14

Legal Events

Date	Code	Title	Description
1993-04-15	UEP	Publication of translation of european patent specification
1996-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE68903031D1 (de)	1992-11-05	N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.
AU666702B2 (en)	1996-02-22	Morphinan derivative and medicinal use
FI914928A0 (fi)	1991-10-18	Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner.
SE8505112D0 (sv)	1985-10-29	Novel pharmacological compounds
DE59010810D1 (de)	1998-04-16	Arzneimittel enthaltend als Wirkstoff R-alpha-Liponsäure oder S-alpha-Liponsäure
ATE143598T1 (de)	1996-10-15	Arzneimittellösung enhaltend derivate von fk506
ATE110071T1 (de)	1994-09-15	Pyridazinon-derivate und diese enthaltende pharmazeutische zubereitungen.
FI931855A0 (fi)	1993-04-23	Farmaceutisk sammansaettning som innehaoller kinolin- och kinazolinderivat samt nya foereningar daerfoer
ATE114154T1 (de)	1994-12-15	Thienotriazolodiazepine und ihre pharmazeutische verwendung.
DK0571243T3 (da)	1995-12-04	Thiochromanderivater, fremgangsmåder til fremstilling heraf samt farmaceutiske midler indeholdende d isse
AU621634B2 (en)	1992-03-19	Glycerin derivative and its pharmacological use
ATE237619T1 (de)	2003-05-15	Sesquiterpen-derivate mit antiviraler aktivität
DK540589D0 (da)	1989-10-30	Pyrrolidinderivater
ES2093051T3 (es)	1996-12-16	Purinil- y pirimidil-tetrahidrofuranos.
DE3675291D1 (de)	1990-12-06	1-alkyl-ergolinyl-thioharnstoffderivate.
ATE89288T1 (de)	1993-05-15	L-pyroglutamyl-l-cystein-dipeptid mit hoher anti- cataractogener wirkung und dies enthaltende pharmazeutische zusammensetzungen.