ATE81009T1 - N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel. - Google Patents
N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel.Info
- Publication number
- ATE81009T1 ATE81009T1 AT89108596T AT89108596T ATE81009T1 AT E81009 T1 ATE81009 T1 AT E81009T1 AT 89108596 T AT89108596 T AT 89108596T AT 89108596 T AT89108596 T AT 89108596T AT E81009 T1 ATE81009 T1 AT E81009T1
- Authority
- AT
- Austria
- Prior art keywords
- acetyl
- fluoroneuraminic
- acid
- antiviral medicine
- fluoroneuraminic acid
- Prior art date
Links
- ALJLGESFXXDPKH-OLUMBMSPSA-N (4R,5R,6R)-5-acetamido-3-fluoro-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C(F)C(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ALJLGESFXXDPKH-OLUMBMSPSA-N 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63116500A JPH01287029A (ja) | 1988-05-13 | 1988-05-13 | 新規抗ウィルス剤 |
| EP89108596A EP0341735B1 (de) | 1988-05-13 | 1989-05-12 | N-acetyl-3-fluoroneuraminsäure als antivirales Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE81009T1 true ATE81009T1 (de) | 1992-10-15 |
Family
ID=14688671
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89108596T ATE81009T1 (de) | 1988-05-13 | 1989-05-12 | N-acetyl-3-fluoroneuraminsaeure als antivirales arzneimittel. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0341735B1 (de) |
| JP (1) | JPH01287029A (de) |
| KR (1) | KR970005326B1 (de) |
| AT (1) | ATE81009T1 (de) |
| AU (1) | AU624138B2 (de) |
| DE (1) | DE68903031T2 (de) |
| DK (1) | DK232989A (de) |
| IL (1) | IL90271A (de) |
| NZ (1) | NZ229128A (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992006691A1 (en) * | 1990-10-19 | 1992-04-30 | Biota Scientific Management Pty. Ltd. | Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus |
| GB9410817D0 (en) * | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| EP2318832B1 (de) | 2008-07-15 | 2013-10-09 | Academia Sinica | Glycan-arrays auf objektträgern mit ptfe-aluminiumbeschichtung und entsprechende verfahren |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| JP6302909B2 (ja) | 2012-08-18 | 2018-03-28 | アカデミア シニカAcademia Sinica | シアリダーゼの同定および画像化のための細胞透過性プローブ |
| US10086054B2 (en) | 2013-06-26 | 2018-10-02 | Academia Sinica | RM2 antigens and use thereof |
| WO2014210564A1 (en) | 2013-06-27 | 2014-12-31 | Academia Sinica | Glycan conjugates and use thereof |
| CA2923579C (en) | 2013-09-06 | 2023-09-05 | Academia Sinica | Human inkt cell activation using glycolipids with altered glycosyl groups |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US9982041B2 (en) | 2014-01-16 | 2018-05-29 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| CN106415244B (zh) | 2014-03-27 | 2020-04-24 | 中央研究院 | 反应性标记化合物及其用途 |
| CN106661099A (zh) | 2014-05-27 | 2017-05-10 | 中央研究院 | 抗her2醣抗体及其用途 |
| US20150344585A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-cd20 glycoantibodies and uses thereof |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| EP3904388A1 (de) | 2014-05-27 | 2021-11-03 | Academia Sinica | Fucosidase aus bacteroiden und verfahren damit |
| EP3154582A4 (de) | 2014-05-28 | 2018-01-10 | Academia Sinica | Anti-tnf-alpha-glycoantikörper und verwendungen davon |
| EP3191500A4 (de) | 2014-09-08 | 2018-04-11 | Academia Sinica | Aktivierung menschlicher inkt-zellen mithilfe von glykolipiden |
| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| CA2972072A1 (en) | 2015-01-24 | 2016-07-28 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
| KR20180114210A (ko) | 2016-03-08 | 2018-10-17 | 아카데미아 시니카 | N-글리칸의 모듈 합성 방법 및 그의 어레이 |
| US10538592B2 (en) | 2016-08-22 | 2020-01-21 | Cho Pharma, Inc. | Antibodies, binding fragments, and methods of use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2573594B2 (ja) * | 1987-03-06 | 1997-01-22 | メクト株式会社 | Nーアセチルー3ーフルオローノイラミン酸誘導体およびその製造方法 |
-
1988
- 1988-05-13 JP JP63116500A patent/JPH01287029A/ja active Pending
-
1989
- 1989-05-12 DE DE8989108596T patent/DE68903031T2/de not_active Expired - Fee Related
- 1989-05-12 DK DK232989A patent/DK232989A/da not_active Application Discontinuation
- 1989-05-12 AU AU34798/89A patent/AU624138B2/en not_active Ceased
- 1989-05-12 IL IL9027189A patent/IL90271A/en unknown
- 1989-05-12 AT AT89108596T patent/ATE81009T1/de not_active IP Right Cessation
- 1989-05-12 EP EP89108596A patent/EP0341735B1/de not_active Expired - Lifetime
- 1989-05-13 KR KR1019890006392A patent/KR970005326B1/ko not_active Expired - Lifetime
- 1989-05-15 NZ NZ229128A patent/NZ229128A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR970005326B1 (ko) | 1997-04-15 |
| DK232989D0 (da) | 1989-05-12 |
| NZ229128A (en) | 1991-05-28 |
| EP0341735B1 (de) | 1992-09-30 |
| DE68903031T2 (de) | 1993-02-18 |
| KR890016966A (ko) | 1989-12-14 |
| AU3479889A (en) | 1989-11-16 |
| AU624138B2 (en) | 1992-06-04 |
| JPH01287029A (ja) | 1989-11-17 |
| DK232989A (da) | 1989-11-14 |
| IL90271A (en) | 1994-04-12 |
| DE68903031D1 (de) | 1992-11-05 |
| EP0341735A1 (de) | 1989-11-15 |
| IL90271A0 (en) | 1989-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |