ATE81254T1 - Neovaskularisierungsinhibitoren und deren herstellung. - Google Patents

Neovaskularisierungsinhibitoren und deren herstellung.

Info

Publication number
ATE81254T1
ATE81254T1 AT86901626T AT86901626T ATE81254T1 AT E81254 T1 ATE81254 T1 AT E81254T1 AT 86901626 T AT86901626 T AT 86901626T AT 86901626 T AT86901626 T AT 86901626T AT E81254 T1 ATE81254 T1 AT E81254T1
Authority
AT
Austria
Prior art keywords
production
neovascularization inhibitors
cells
polypeptides
neovascularization
Prior art date
Application number
AT86901626T
Other languages
English (en)
Inventor
Bert M Glaser
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE81254T1 publication Critical patent/ATE81254T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/849—Eyes; vessels; umbilical cord

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT86901626T 1985-02-26 1986-02-14 Neovaskularisierungsinhibitoren und deren herstellung. ATE81254T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70625985A 1985-02-26 1985-02-26
EP86901626A EP0213180B1 (de) 1985-02-26 1986-02-14 Neovaskularisierungsinhibitoren und deren herstellung
PCT/US1986/000312 WO1986004783A1 (en) 1985-02-26 1986-02-14 Neovascularization inhibitors and methods for their production and use

Publications (1)

Publication Number Publication Date
ATE81254T1 true ATE81254T1 (de) 1992-10-15

Family

ID=24836851

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86901626T ATE81254T1 (de) 1985-02-26 1986-02-14 Neovaskularisierungsinhibitoren und deren herstellung.

Country Status (12)

Country Link
US (1) US4996159A (de)
EP (1) EP0213180B1 (de)
JP (1) JPS61246132A (de)
AT (1) ATE81254T1 (de)
AU (1) AU590872B2 (de)
DE (1) DE3686927T2 (de)
DK (1) DK509286A (de)
FI (1) FI864293A0 (de)
NO (1) NO864254L (de)
NZ (1) NZ215195A (de)
WO (1) WO1986004783A1 (de)
ZA (1) ZA861403B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329123C (en) * 1987-10-13 1994-05-03 Moses Judah Folkman Inhibitor of angiogenesis
JPH04178328A (ja) * 1990-11-08 1992-06-25 Unitika Ltd 血管新生阻害剤
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
JPH08500255A (ja) * 1992-04-01 1996-01-16 バクスター・インターナショナル・インコーポレーテッド 血管形成組織移植システムおよびその方法
US5840686A (en) * 1992-09-24 1998-11-24 The United States Of America As Represented By The Department Of Health And Human Services Pigment epithelium-derived factor: characterization of its novel biological activity and sequences encoding and expressing the protein and methods of use
US6451763B1 (en) * 1992-06-04 2002-09-17 The United States Of America As Represented By The Department Of Health And Human Services Retinal pigmented epithelium derived neurotrophic factor and methods of use
US6319687B1 (en) 1992-09-24 2001-11-20 The United States Of America As Represented By The Department Of Health And Human Services Pigment epithelium-derived factor: characterization, genomic organization and sequence of PEDF gene
US5886026A (en) * 1993-07-19 1999-03-23 Angiotech Pharmaceuticals Inc. Anti-angiogenic compositions and methods of use
US5985330A (en) * 1996-08-05 1999-11-16 Coastside Bio Resources Inhibition of angiogenesis by sea cucumber fractions
EP0957901B1 (de) 1996-12-31 2009-11-18 Antioxidant Pharmaceuticals Corporation Pharmazeutische glutathionpräparate und methoden zu dern verabreichung
CA2298018C (en) 1997-07-23 2008-12-16 Northwestern University Methods and compositions for inhibiting angiogenesis
US7105496B2 (en) * 1998-07-23 2006-09-12 Northwestern University Methods and compositions for inhibiting angiogenesis
US6797691B1 (en) * 1997-07-23 2004-09-28 Northwestern University Methods and compositions for inhibiting angiogenesis
US7828827B2 (en) * 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6875165B2 (en) 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye
US7070554B2 (en) 2003-01-15 2006-07-04 Theragenics Corporation Brachytherapy devices and methods of using them
EP2298412A1 (de) * 2004-02-12 2011-03-23 Neovista, Inc. Vorrichtung für die intraokulare Brachytherapie
US7563222B2 (en) 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
BRPI0618677A2 (pt) * 2005-11-15 2011-09-06 Neovista Inc métodos e aparelho para braquiterapia intra-ocular
US8821446B2 (en) * 2007-01-22 2014-09-02 Corium International, Inc. Applicators for microneedles
ES2817249T3 (es) 2007-04-16 2021-04-06 Corium Inc Matrices de microagujas obtenidas mediante disolución y colada que contienen un principio activo
WO2009048607A1 (en) * 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2009149175A1 (en) 2008-06-04 2009-12-10 Neovista, Inc. Handheld radiation delivery system for advancing a radiation source wire
EP2429627B1 (de) * 2009-04-24 2017-06-14 Corium International, Inc. Verfahren zur herstellung von mikroprojektionsarrays
EP2566501B1 (de) 2010-05-04 2019-03-13 Corium International, Inc. Verfahren und vorrichtung zur transdermalen verabreichung von parathormon mithilfe eines mikroprojektions-arrays
EP2934660B1 (de) 2012-12-21 2019-07-17 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur herstellung davon
EP4094799A1 (de) 2013-03-12 2022-11-30 Corium, Inc. Mikroprojektionsapplikatoren
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
US20160367620A1 (en) 2015-06-19 2016-12-22 Harry B. Demopoulos Glutathione
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30239A (en) * 1860-10-02 Improvement in machines for stem m ing corn-husks
US4042457A (en) * 1975-11-10 1977-08-16 Rush-Presbyterian-St. Luke's Medical Center Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor
USRE30239E (en) * 1975-11-10 1980-03-25 Cell proliferation and tissue invasion inhibitor
US4182753A (en) * 1978-03-29 1980-01-08 Saltarelli Cora G Sarcoma 180 tumor inhibitor and method of making same
US4176177A (en) * 1978-11-16 1979-11-27 Rush-Presbyterian-St. Luke's Medical Center Inhibition of bone resorption
US4356261A (en) * 1980-04-22 1982-10-26 Rush-Presbyterian-St. Luke's Medical Center Anti-invasion factor containing cultures
US4534967A (en) * 1982-08-03 1985-08-13 Boston Biomedical Research Institute Cell proliferation inhibitor and method of preparation

Also Published As

Publication number Publication date
DK509286D0 (da) 1986-10-24
WO1986004783A1 (en) 1986-08-28
DE3686927D1 (de) 1992-11-12
JPS61246132A (ja) 1986-11-01
DE3686927T2 (de) 1993-03-25
ZA861403B (en) 1986-12-30
FI864293A7 (fi) 1986-10-23
FI864293L (fi) 1986-10-23
AU590872B2 (en) 1989-11-23
FI864293A0 (fi) 1986-10-23
DK509286A (da) 1986-10-24
EP0213180A1 (de) 1987-03-11
EP0213180B1 (de) 1992-10-07
NO864254L (no) 1986-10-23
NZ215195A (en) 1991-11-26
EP0213180A4 (de) 1988-12-28
US4996159A (en) 1991-02-26
AU5455386A (en) 1986-09-10

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee