ATE81254T1 - Neovaskularisierungsinhibitoren und deren herstellung. - Google Patents

Neovaskularisierungsinhibitoren und deren herstellung.

Info

Publication number
ATE81254T1
ATE81254T1 AT86901626T AT86901626T ATE81254T1 AT E81254 T1 ATE81254 T1 AT E81254T1 AT 86901626 T AT86901626 T AT 86901626T AT 86901626 T AT86901626 T AT 86901626T AT E81254 T1 ATE81254 T1 AT E81254T1
Authority
AT
Austria
Prior art keywords
production
neovascularization inhibitors
cells
polypeptides
neovascularization
Prior art date
Application number
AT86901626T
Other languages
English (en)
Inventor
Bert M Glaser
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE81254T1 publication Critical patent/ATE81254T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/849—Eyes; vessels; umbilical cord

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT86901626T 1985-02-26 1986-02-14 Neovaskularisierungsinhibitoren und deren herstellung. ATE81254T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70625985A 1985-02-26 1985-02-26
PCT/US1986/000312 WO1986004783A1 (en) 1985-02-26 1986-02-14 Neovascularization inhibitors and methods for their production and use
EP86901626A EP0213180B1 (de) 1985-02-26 1986-02-14 Neovaskularisierungsinhibitoren und deren herstellung

Publications (1)

Publication Number Publication Date
ATE81254T1 true ATE81254T1 (de) 1992-10-15

Family

ID=24836851

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86901626T ATE81254T1 (de) 1985-02-26 1986-02-14 Neovaskularisierungsinhibitoren und deren herstellung.

Country Status (12)

Country Link
US (1) US4996159A (de)
EP (1) EP0213180B1 (de)
JP (1) JPS61246132A (de)
AT (1) ATE81254T1 (de)
AU (1) AU590872B2 (de)
DE (1) DE3686927T2 (de)
DK (1) DK509286D0 (de)
FI (1) FI864293A0 (de)
NO (1) NO864254L (de)
NZ (1) NZ215195A (de)
WO (1) WO1986004783A1 (de)
ZA (1) ZA861403B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1329123C (en) * 1987-10-13 1994-05-03 Moses Judah Folkman Inhibitor of angiogenesis
JPH04178328A (ja) * 1990-11-08 1992-06-25 Unitika Ltd 血管新生阻害剤
US5853746A (en) * 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
CA2132016A1 (en) * 1992-04-01 1994-10-14 Baxter International Inc. Angiogenic tissue implant systems and methods
US6319687B1 (en) 1992-09-24 2001-11-20 The United States Of America As Represented By The Department Of Health And Human Services Pigment epithelium-derived factor: characterization, genomic organization and sequence of PEDF gene
US6451763B1 (en) 1992-06-04 2002-09-17 The United States Of America As Represented By The Department Of Health And Human Services Retinal pigmented epithelium derived neurotrophic factor and methods of use
US5840686A (en) * 1992-09-24 1998-11-24 The United States Of America As Represented By The Department Of Health And Human Services Pigment epithelium-derived factor: characterization of its novel biological activity and sequences encoding and expressing the protein and methods of use
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
US5985330A (en) * 1996-08-05 1999-11-16 Coastside Bio Resources Inhibition of angiogenesis by sea cucumber fractions
AU5620598A (en) 1996-12-31 1998-07-31 Antioxidant Pharmaceuticals Corporation Pharmaceutical preparations of glutathione and methods of administration thereof
CA2298018C (en) 1997-07-23 2008-12-16 Northwestern University Methods and compositions for inhibiting angiogenesis
US6797691B1 (en) * 1997-07-23 2004-09-28 Northwestern University Methods and compositions for inhibiting angiogenesis
US7105496B2 (en) * 1998-07-23 2006-09-12 Northwestern University Methods and compositions for inhibiting angiogenesis
US7828827B2 (en) * 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US6875165B2 (en) * 2001-02-22 2005-04-05 Retinalabs, Inc. Method of radiation delivery to the eye
US7070554B2 (en) 2003-01-15 2006-07-04 Theragenics Corporation Brachytherapy devices and methods of using them
US7563222B2 (en) 2004-02-12 2009-07-21 Neovista, Inc. Methods and apparatus for intraocular brachytherapy
CN101005873B (zh) * 2004-02-12 2010-07-21 内奥维斯塔公司 用于眼内近程治疗的设备
AU2006315425A1 (en) * 2005-11-15 2007-05-24 Neovista Inc. Methods and apparatus for intraocular brachytherapy
WO2008091602A2 (en) * 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
US8911749B2 (en) * 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2296756A1 (de) 2008-06-04 2011-03-23 Neovista, Inc. Tragbares bestrahlungssystem zum vorschieben eines strahlungsquellendrahtes
ES2634667T3 (es) * 2009-04-24 2017-09-28 Corium International, Inc. Métodos para fabricar conjuntos de microproyección
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
KR102265808B1 (ko) 2012-12-21 2021-06-16 코리움, 인크. 치료제의 전달을 위한 마이크로어레이 및 그것의 사용방법
CA2903748C (en) 2013-03-12 2021-11-02 Corium International, Inc. Microprojection applicators
AU2014237357B2 (en) 2013-03-15 2019-11-28 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators and methods of use
WO2014151654A1 (en) 2013-03-15 2014-09-25 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
EP3188714A1 (de) 2014-09-04 2017-07-12 Corium International, Inc. Mikrostrukturanordnung, verfahren zur herstellung und verfahren zur verwendung
US20160367620A1 (en) 2015-06-19 2016-12-22 Harry B. Demopoulos Glutathione
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30239A (en) * 1860-10-02 Improvement in machines for stem m ing corn-husks
US4042457A (en) * 1975-11-10 1977-08-16 Rush-Presbyterian-St. Luke's Medical Center Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor
USRE30239E (en) * 1975-11-10 1980-03-25 Cell proliferation and tissue invasion inhibitor
US4182753A (en) * 1978-03-29 1980-01-08 Saltarelli Cora G Sarcoma 180 tumor inhibitor and method of making same
US4176177A (en) * 1978-11-16 1979-11-27 Rush-Presbyterian-St. Luke's Medical Center Inhibition of bone resorption
US4356261A (en) * 1980-04-22 1982-10-26 Rush-Presbyterian-St. Luke's Medical Center Anti-invasion factor containing cultures
US4534967A (en) * 1982-08-03 1985-08-13 Boston Biomedical Research Institute Cell proliferation inhibitor and method of preparation

Also Published As

Publication number Publication date
AU590872B2 (en) 1989-11-23
US4996159A (en) 1991-02-26
ZA861403B (en) 1986-12-30
WO1986004783A1 (en) 1986-08-28
FI864293L (fi) 1986-10-23
DE3686927D1 (de) 1992-11-12
FI864293A7 (fi) 1986-10-23
DK509286A (da) 1986-10-24
NZ215195A (en) 1991-11-26
AU5455386A (en) 1986-09-10
FI864293A0 (fi) 1986-10-23
JPS61246132A (ja) 1986-11-01
EP0213180A1 (de) 1987-03-11
NO864254L (no) 1986-10-23
DK509286D0 (da) 1986-10-24
EP0213180A4 (de) 1988-12-28
DE3686927T2 (de) 1993-03-25
EP0213180B1 (de) 1992-10-07

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee