ATE81285T1 - Freisetzungssysteme fuer die kontrollierte anwendung von lhrh-analoga. - Google Patents
Freisetzungssysteme fuer die kontrollierte anwendung von lhrh-analoga.Info
- Publication number
- ATE81285T1 ATE81285T1 AT88107345T AT88107345T ATE81285T1 AT E81285 T1 ATE81285 T1 AT E81285T1 AT 88107345 T AT88107345 T AT 88107345T AT 88107345 T AT88107345 T AT 88107345T AT E81285 T1 ATE81285 T1 AT E81285T1
- Authority
- AT
- Austria
- Prior art keywords
- delivery systems
- controlled use
- lhrh analogues
- controlled
- lhrh analog
- Prior art date
Links
- XLXSAKCOAKORKW-UHFFFAOYSA-N gonadorelin Chemical class C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 XLXSAKCOAKORKW-UHFFFAOYSA-N 0.000 title abstract 3
- 239000002434 gonadorelin derivative Substances 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920002379 silicone rubber Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/2036—Silicones; Polysiloxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Reproductive Health (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Polyesters Or Polycarbonates (AREA)
- Reduction Or Emphasis Of Bandwidth Of Signals (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/047,738 US5028430A (en) | 1987-05-08 | 1987-05-08 | Delivery systems for the controlled administration of LHRH analogs |
| EP88107345A EP0293632B1 (de) | 1987-05-08 | 1988-05-06 | Freisetzungssysteme für die kontrollierte Anwendung von LHRH-Analoga |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE81285T1 true ATE81285T1 (de) | 1992-10-15 |
Family
ID=21950670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88107345T ATE81285T1 (de) | 1987-05-08 | 1988-05-06 | Freisetzungssysteme fuer die kontrollierte anwendung von lhrh-analoga. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5028430A (de) |
| EP (1) | EP0293632B1 (de) |
| JP (1) | JPH0686391B2 (de) |
| AT (1) | ATE81285T1 (de) |
| AU (1) | AU621294B2 (de) |
| CA (1) | CA1336579C (de) |
| DE (1) | DE3875160T2 (de) |
| ES (1) | ES2052636T3 (de) |
| GR (1) | GR3005901T3 (de) |
| IE (1) | IE62969B1 (de) |
| NZ (1) | NZ224520A (de) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0657170A1 (de) * | 1993-12-09 | 1995-06-14 | ASTA Medica Aktiengesellschaft | Erzeugnisse zur Anwendung von initial hohen Dosen von Cetrorelix und Herstellung einer Kombinationspackung zur Verwendung bei Therapie von Krankheiten |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5387419A (en) * | 1988-03-31 | 1995-02-07 | The University Of Michigan | System for controlled release of antiarrhythmic agents |
| IL87982A0 (en) * | 1988-10-10 | 1989-03-31 | Israel Oceanographic & Limnolo | Compositions and methods for manipulating ovulation and spawning in fish |
| MY107937A (en) * | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
| ES2136624T3 (es) * | 1991-10-21 | 1999-12-01 | Peptech Limited | Implante biocompatible para regular la ovulacion en yeguas. |
| ES2150427T3 (es) * | 1992-06-02 | 2000-12-01 | Bard Inc C R | Procedimiento y dispositivo de implante para el suministro de farmacos a largo plazo. |
| US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US5733565A (en) * | 1996-02-23 | 1998-03-31 | The Population Council, Center For Biomedical Research | Male contraceptive implant |
| US20070185032A1 (en) * | 1996-12-11 | 2007-08-09 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
| US5968895A (en) | 1996-12-11 | 1999-10-19 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
| US6117441A (en) * | 1998-07-02 | 2000-09-12 | The Population Council, Inc. | Silicone core long term androgen delivery implant |
| US7029694B2 (en) | 2000-04-26 | 2006-04-18 | Watson Laboratories, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| CN1438861A (zh) | 2000-04-26 | 2003-08-27 | 沃特森药物公司 | 最小化与奥昔布宁疗法有关的副作用 |
| US7179483B2 (en) * | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| US20030124177A1 (en) * | 2000-04-26 | 2003-07-03 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| AUPR602501A0 (en) * | 2001-06-29 | 2001-07-26 | Smart Drug Systems Inc | Sustained release pharmaceutical composition |
| AUPR602401A0 (en) * | 2001-06-29 | 2001-07-26 | Smart Drug Systems Inc | Sustained release delivery system |
| US20040234572A1 (en) * | 2001-09-11 | 2004-11-25 | Martinod Serge R. | Preparation of sustained release pharmaceutical composition |
| US20060193825A1 (en) * | 2003-04-29 | 2006-08-31 | Praecis Phamaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
| US20050112087A1 (en) * | 2003-04-29 | 2005-05-26 | Musso Gary F. | Pharmaceutical formulations for sustained drug delivery |
| JP2008500973A (ja) * | 2004-05-31 | 2008-01-17 | スマート ドラッグ システムズ インコーポレイティド | 持続放出組成物 |
| US20120156049A1 (en) * | 2005-12-14 | 2012-06-21 | Hong Shek C | Method and coating for protecting and repairing an airfoil surface |
| US20090162416A1 (en) * | 2007-12-19 | 2009-06-25 | Dunham Rex A | Polymer implants for timed release of drugs with particular emphasis on ovulation or spermiation of fish |
| US20120163981A1 (en) * | 2010-12-22 | 2012-06-28 | Hong Shek C | Method and coating for protecting and repairing an airfoil surface |
| CN111278902B (zh) * | 2017-11-23 | 2022-01-04 | 丹麦科技大学 | 具有可控释放曲线的作为活性基体的甘油-有机硅弹性体 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791632A (fr) * | 1971-11-20 | 1973-05-21 | Schering Ag | Supports a base de caoutchouc siliconique pour agents medicamenteux |
| US4391797A (en) * | 1977-01-05 | 1983-07-05 | The Children's Hospital Medical Center | Systems for the controlled release of macromolecules |
| IT1149971B (it) * | 1979-06-11 | 1986-12-10 | Syntex Inc | Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante |
| US4234571A (en) * | 1979-06-11 | 1980-11-18 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
| US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| PH19942A (en) * | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4581169A (en) * | 1982-12-21 | 1986-04-08 | Syntex (U.S.A.) Inc. | Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists |
| US4481190A (en) * | 1982-12-21 | 1984-11-06 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists |
| JPS62174031A (ja) * | 1985-10-11 | 1987-07-30 | Sumitomo Pharmaceut Co Ltd | 高分子量薬物含有徐放性製剤 |
| NZ217844A (en) * | 1985-10-11 | 1989-10-27 | Sumitomo Pharma | A sustained release pharmaceutical composition containing silicone elastomer and an albumin |
| US4959217A (en) * | 1986-05-22 | 1990-09-25 | Syntex (U.S.A.) Inc. | Delayed/sustained release of macromolecules |
-
1987
- 1987-05-08 US US07/047,738 patent/US5028430A/en not_active Expired - Fee Related
-
1988
- 1988-05-06 EP EP88107345A patent/EP0293632B1/de not_active Expired - Lifetime
- 1988-05-06 JP JP63111389A patent/JPH0686391B2/ja not_active Expired - Lifetime
- 1988-05-06 ES ES88107345T patent/ES2052636T3/es not_active Expired - Lifetime
- 1988-05-06 CA CA000566179A patent/CA1336579C/en not_active Expired - Lifetime
- 1988-05-06 AU AU15682/88A patent/AU621294B2/en not_active Expired
- 1988-05-06 AT AT88107345T patent/ATE81285T1/de not_active IP Right Cessation
- 1988-05-06 DE DE8888107345T patent/DE3875160T2/de not_active Expired - Lifetime
- 1988-05-06 NZ NZ224520A patent/NZ224520A/en unknown
- 1988-05-06 IE IE136588A patent/IE62969B1/en not_active IP Right Cessation
-
1992
- 1992-10-08 GR GR920401565T patent/GR3005901T3/el unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0657170A1 (de) * | 1993-12-09 | 1995-06-14 | ASTA Medica Aktiengesellschaft | Erzeugnisse zur Anwendung von initial hohen Dosen von Cetrorelix und Herstellung einer Kombinationspackung zur Verwendung bei Therapie von Krankheiten |
| US5663145A (en) * | 1993-12-09 | 1997-09-02 | Asta Medica Aktiengesellschaft | Products for administering an initial high dose of Cetrorelix and producing a combination package for use when treating diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0293632B1 (de) | 1992-10-07 |
| EP0293632A1 (de) | 1988-12-07 |
| CA1336579C (en) | 1995-08-08 |
| ES2052636T3 (es) | 1994-07-16 |
| DE3875160D1 (de) | 1992-11-12 |
| IE881365L (en) | 1988-11-08 |
| AU1568288A (en) | 1988-11-10 |
| JPH0686391B2 (ja) | 1994-11-02 |
| JPS6445318A (en) | 1989-02-17 |
| NZ224520A (en) | 1990-12-21 |
| GR3005901T3 (de) | 1993-06-07 |
| AU621294B2 (en) | 1992-03-12 |
| DE3875160T2 (de) | 1993-03-18 |
| US5028430A (en) | 1991-07-02 |
| IE62969B1 (en) | 1995-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |