ATE81288T1 - Verkapselung von trh bzw. dessen analoga. - Google Patents

Verkapselung von trh bzw. dessen analoga.

Info

Publication number
ATE81288T1
ATE81288T1 AT87306794T AT87306794T ATE81288T1 AT E81288 T1 ATE81288 T1 AT E81288T1 AT 87306794 T AT87306794 T AT 87306794T AT 87306794 T AT87306794 T AT 87306794T AT E81288 T1 ATE81288 T1 AT E81288T1
Authority
AT
Austria
Prior art keywords
trh
analogs
encapsulation
active ingredient
release
Prior art date
Application number
AT87306794T
Other languages
English (en)
Inventor
Toshiro Heya
Hiroaki Okada
Yasuaki - Koaza-Tanita Ogawa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE81288T1 publication Critical patent/ATE81288T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/066TRH, thyroliberin, thyrotropin releasing hormone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Networks Using Active Elements (AREA)
  • Amplifiers (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT87306794T 1986-08-08 1987-07-31 Verkapselung von trh bzw. dessen analoga. ATE81288T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18746786 1986-08-08
EP87306794A EP0256726B1 (de) 1986-08-08 1987-07-31 Verkapselung von TRH bzw. dessen Analoga

Publications (1)

Publication Number Publication Date
ATE81288T1 true ATE81288T1 (de) 1992-10-15

Family

ID=16206591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87306794T ATE81288T1 (de) 1986-08-08 1987-07-31 Verkapselung von trh bzw. dessen analoga.

Country Status (7)

Country Link
US (1) US5652220A (de)
EP (1) EP0256726B1 (de)
JP (1) JP2526589B2 (de)
KR (1) KR880002514A (de)
AT (1) ATE81288T1 (de)
CA (1) CA1300011C (de)
DE (1) DE3782117T2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5271945A (en) * 1988-07-05 1993-12-21 Takeda Chemical Industries, Ltd. Sustained release microcapsule for water soluble drug
ATE133865T1 (de) * 1989-11-17 1996-02-15 Takeda Chemical Industries Ltd Therapeutisches mittel für erkrankungen des zentralnervensystems
MY107937A (en) * 1990-02-13 1996-06-29 Takeda Chemical Industries Ltd Prolonged release microcapsules.
JP2653255B2 (ja) * 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
JPH04124127A (ja) * 1990-09-14 1992-04-24 Chugai Pharmaceut Co Ltd マイクロカプセル型徐放性製剤及びその製造法
ZA918168B (en) * 1990-10-16 1993-04-14 Takeda Chemical Industries Ltd Prolonged release preparation and polymers thereof.
AU685784B2 (en) * 1993-02-23 1998-01-29 Genentech Inc. Excipient stabilization of polypeptides treated with organic solvents
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6149953A (en) * 1993-11-08 2000-11-21 Delta Food Group, Inc. Seeded microcapsules
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
US6303134B1 (en) 1996-08-29 2001-10-16 Advanced Research And Technology Institute, Inc. Pharmacotherapeutic process and composition for central nervous system disorders
WO2001080830A2 (en) 2000-04-21 2001-11-01 Advanced Research And Technology Institute, Inc. Pharmacotherapeutic process and composition for central nervous system disorders
DE10025948A1 (de) * 2000-05-26 2001-11-29 Gruenenthal Gmbh Wirkstoffkombination
US20040126900A1 (en) * 2001-04-13 2004-07-01 Barry Stephen E High affinity peptide- containing nanoparticles
FR2867075B1 (fr) * 2004-03-03 2006-07-14 Ethypharm Sa Procede de preparation de microspheres biodegradables calibrees
US20080305175A1 (en) * 2006-11-30 2008-12-11 Agency For Science, Technology And Research Micro-Container

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792550A (nl) * 1971-12-23 1973-06-12 Agfa Gevaert Nv Procede voor het vervaardigen van microcapsules
JPS5944308B2 (ja) * 1976-03-23 1984-10-29 武田薬品工業株式会社 ペプタイド
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
JPS57188526A (en) * 1981-05-14 1982-11-19 Takeda Chem Ind Ltd Peptide-containing pharmaceutical preparation
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
JPS60125245A (ja) * 1983-12-12 1985-07-04 Nitto Electric Ind Co Ltd 液状活性物質含有マイクロカプセルの製造方法
DE3678308D1 (de) * 1985-02-07 1991-05-02 Takeda Chemical Industries Ltd Verfahren zur herstellung von mikrokapseln.

Also Published As

Publication number Publication date
JPS63233926A (ja) 1988-09-29
US5652220A (en) 1997-07-29
EP0256726B1 (de) 1992-10-07
DE3782117T2 (de) 1993-03-11
EP0256726A3 (en) 1988-04-20
EP0256726A2 (de) 1988-02-24
DE3782117D1 (de) 1992-11-12
KR880002514A (ko) 1988-05-09
CA1300011C (en) 1992-05-05
JP2526589B2 (ja) 1996-08-21

Similar Documents

Publication Publication Date Title
ATE81288T1 (de) Verkapselung von trh bzw. dessen analoga.
EP0184942A3 (en) Improved pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient
EP0350246A3 (en) Sustained release microcapsule for water soluble drug
DE3882906D1 (de) Feine weichmikrokapseln enthaltendes kosmetisches praeparat.
DE3477137D1 (en) Aqueous solution containing lipid-soluble pharmaceutical substance and a process for preparing the same
DE3853566D1 (de) Formulierungen von Tetrazyklinverbindungen mit kontrollierter Freisetzung.
ATE137963T1 (de) Lh-rh-analoga enthaltende formulierungen
DE59010810D1 (de) Arzneimittel enthaltend als Wirkstoff R-alpha-Liponsäure oder S-alpha-Liponsäure
HUT52070A (en) Herbicide compositions containing pyrimidinyl-benzoic acid derivatives as active components, and process for producing the active components
TW234691B (de)
EP0186071A3 (en) Transdermal system for timolol
ZA90946B (en) Medicament containing dihydrolipoic acid as active substance
GR3006426T3 (de)
GR3004959T3 (de)
HUT47793A (en) Herbicide compositions containing 2,6-substituted-pyridine-carboxylic acid derivatives as active components and process for producing the active components
ATE115579T1 (de) Imidazolsulfonamid-derivate, herbizide und verfahren zur bekämpfung von schadpflanzen.
DE58903876D1 (de) Riboflavin-4'5'-cyclo-phosphorsaeureesterchlorid, dessen herstellung und verwendung zur herstellung von riboflavin-5'-phosphat (5'-fmn) bzw. dessen natriumsalz.
HUT44909A (en) Herbicides comprising 1-aryl-4-substituted-1,4-dihydro-5h-tetrazol-5-one derivatives and their sulphur analogs as active ingredient and process for producing the active ingredients and intermediaries thereof
DE3662143D1 (en) Novel carboxylic acid esters, methods for production thereof and insecticides containing them as the active ingredient
HUT47792A (en) Herbicide compositions containing 2,6-substituted-pyridine-carboxylic acid derivatives as active components and process for producing the active components
PT80961B (en) Process for the preparation of new pharmaceutical compounds containing mixtures of 4,9-dihydro-4-(1-methyl-4-piperydilene)-10h-benzoý4,5¨-cycloheptaý1,2-b¨thyophene-10-one and antiasthmati c xantines as active ingredient
JPS6420261A (en) Aqueous composition containing polymerized fatty acid polyamide
ATE20230T1 (de) Spasmolytisch wirksames (+)s-enantiomer von secoverin.
IL81330A (en) 10-carboxy-2,2-disubstituted-5-(cyclic)amino-2,3-dihydro-3-oxo-imidazo-(1',2':3',4)-imidazo(5,1-a)-pyridinium inner salts and ylides and analogs thereof,their preparation and herbicidal use
EG12070A (en) Agent for regulating plant growth containing as active ingredient 2-cyano-bicyclo(2,2,1)heptane

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties