ATE82135T1 - Synthetische hepatitis-b-virus-vakzine die tzellen- und b-zellenbestimmer enthalten. - Google Patents

Synthetische hepatitis-b-virus-vakzine die tzellen- und b-zellenbestimmer enthalten.

Info

Publication number
ATE82135T1
ATE82135T1 AT85301588T AT85301588T ATE82135T1 AT E82135 T1 ATE82135 T1 AT E82135T1 AT 85301588 T AT85301588 T AT 85301588T AT 85301588 T AT85301588 T AT 85301588T AT E82135 T1 ATE82135 T1 AT E82135T1
Authority
AT
Austria
Prior art keywords
cell
determiners
hepatitis
virus vaccine
vaccine containing
Prior art date
Application number
AT85301588T
Other languages
English (en)
Inventor
David R Milich
Frank V Chisari
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/587,983 external-priority patent/US4599231A/en
Priority claimed from US06/588,122 external-priority patent/US4599230A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Application granted granted Critical
Publication of ATE82135T1 publication Critical patent/ATE82135T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Selective Calling Equipment (AREA)
  • Air Bags (AREA)
AT85301588T 1984-03-09 1985-03-07 Synthetische hepatitis-b-virus-vakzine die tzellen- und b-zellenbestimmer enthalten. ATE82135T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/587,983 US4599231A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US06/588,122 US4599230A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
EP85301588A EP0155146B1 (de) 1984-03-09 1985-03-07 Synthetische Hepatitis-B-Virus-Vakzine die T-Zellen- und B-Zellenbestimmer enthalten

Publications (1)

Publication Number Publication Date
ATE82135T1 true ATE82135T1 (de) 1992-11-15

Family

ID=27080174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85301588T ATE82135T1 (de) 1984-03-09 1985-03-07 Synthetische hepatitis-b-virus-vakzine die tzellen- und b-zellenbestimmer enthalten.

Country Status (11)

Country Link
EP (1) EP0155146B1 (de)
AT (1) ATE82135T1 (de)
AU (2) AU579148B2 (de)
CA (1) CA1253069A (de)
DE (1) DE3586801D1 (de)
DK (1) DK516385A (de)
FI (1) FI84558C (de)
IL (3) IL74545A (de)
NO (1) NO167359C (de)
NZ (2) NZ211356A (de)
WO (1) WO1985004103A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
WO1987007896A1 (en) * 1986-06-20 1987-12-30 Scripps Clinic And Research Foundation T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen
US6222020B1 (en) * 1987-01-07 2001-04-24 Imperial Cancer Research Technology Limited Antigens derived from the core protein of the human mammary epithelial mucin
EP0293201A3 (de) * 1987-05-26 1990-02-28 The Wistar Institute Methode zur Impfung gegen Hepatitis-B-Virus
IL86832A (en) 1987-06-22 2002-09-12 Medeva Holdings Bv A recombinant DNA molecule containing a nucleotide sequence of part of the region encoding HBV pre-1s, an immunogenic particle containing multiple peptide monomers containing a pre-s1 epitope and pharmaceutical preparations containing it
WO1989001943A1 (en) * 1987-09-04 1989-03-09 Whitehead Institute For Biomedical Research Peptide complexes having enhanced stability
EP0491077A1 (de) * 1990-12-19 1992-06-24 Medeva Holdings B.V. Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten
GB9325772D0 (en) * 1993-12-16 1994-02-16 Smithkline Beecham Biolog Novel compounds
CA2251904A1 (en) * 1996-04-18 1997-10-23 Abbott Laboratories An antigenic epitope of the a determinant of hepatitis b surface antigen and uses thereof
EP2298900A1 (de) 1996-09-17 2011-03-23 Novartis Vaccines and Diagnostics, Inc. Zusammensetzungen und Verfahren zur Behandlung intrazellulärer Erkrankungen
WO1998029442A1 (en) * 1996-12-30 1998-07-09 Innogenetics N.V. ANNEXIN V-BINDING POLYPEPTIDES DERIVED FROM HBsAg AND THEIR USES
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
ES2330904B1 (es) 2005-09-21 2010-09-23 Fundacio Centre De Recerca En Sanitat Animal Polinucleotidos de haemophilus parasuis y su uso.
WO2008017517A1 (en) 2006-08-11 2008-02-14 Life Sciences Research Partners Vzw Immunogenic peptides and their use in immune disorders
US20120009678A1 (en) 2008-02-14 2012-01-12 Jean-Marie Saint-Remy Immunotherapy targeting intracellular pathogens
WO2009101205A2 (en) 2008-02-14 2009-08-20 Life Sciences Research Partners Vzw Immunogenic control of tumours and tumour cells
US10023847B2 (en) 2010-11-25 2018-07-17 Imnate Sarl Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
ES2834072T3 (es) * 2012-06-11 2021-06-16 Univ Xiamen Polipéptidos y anticuerpos para el tratamiento de la infección por vhb y enfermedades relacionadas
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
EP3352782B1 (de) 2015-09-25 2021-03-31 ImCyse SA Verbesserte verfahren und verbindungen zur beseitigung von immunreaktionen auf therapeutische mittel
WO2017182528A1 (en) 2016-04-19 2017-10-26 Imcyse Sa Novel immunogenic cd1d binding peptides
EP3617317A4 (de) 2017-02-17 2021-01-13 Xiamen University Peptidträger zur anzeige eines zielpolypeptids und verwendung davon

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
YU44186B (en) * 1978-12-22 1990-04-30 Biogen Nv Process for obtaining recombinant dnk molecules
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
IL61904A (en) * 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
EP0082789B1 (de) * 1981-12-22 1987-04-08 Baylor College of Medicine Immunologische Zusammensetzung und Methode für Hepatitis-B-Virus
US4483793A (en) * 1982-10-04 1984-11-20 The Regents Of The University Of California Dimeric oligopeptides as heptenic epitopic sites for hepatitis
JPS5974985A (ja) * 1982-10-19 1984-04-27 Takeda Chem Ind Ltd 新規ｄｎａ
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids

Also Published As

Publication number Publication date
DE3586801D1 (de) 1992-12-17
IL74545A (en) 1990-11-05
FI854396A0 (fi) 1985-11-07
FI84558B (fi) 1991-09-13
AU623106B2 (en) 1992-05-07
AU579148B2 (en) 1988-11-17
IL74545A0 (en) 1985-06-30
NO854460L (no) 1986-01-08
CA1253069A (en) 1989-04-25
NO167359B (no) 1991-07-22
NO167359C (no) 1991-10-30
EP0155146A2 (de) 1985-09-18
EP0155146A3 (en) 1988-01-20
FI854396L (fi) 1985-11-07
AU4115985A (en) 1985-10-11
IL90035A0 (en) 1989-12-15
IL90035A (en) 1990-11-05
EP0155146B1 (de) 1992-11-11
DK516385D0 (da) 1985-11-08
FI84558C (fi) 1991-12-27
DK516385A (da) 1985-11-08
NZ227731A (en) 1990-07-26
NZ211356A (en) 1990-07-26
WO1985004103A1 (en) 1985-09-26
AU2682388A (en) 1989-05-25

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