DK516385A - Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter - Google Patents

Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter Download PDF

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Publication number
DK516385A
DK516385A DK516385A DK516385A DK516385A DK 516385 A DK516385 A DK 516385A DK 516385 A DK516385 A DK 516385A DK 516385 A DK516385 A DK 516385A DK 516385 A DK516385 A DK 516385A
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DK
Denmark
Prior art keywords
bcelle
celle
determinants
against hepatitis
vaccine against
Prior art date
Application number
DK516385A
Other languages
English (en)
Other versions
DK516385D0 (da
Inventor
David R Milich
Frank V Chisari
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/588,122 external-priority patent/US4599230A/en
Priority claimed from US06/587,983 external-priority patent/US4599231A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK516385A publication Critical patent/DK516385A/da
Publication of DK516385D0 publication Critical patent/DK516385D0/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Selective Calling Equipment (AREA)
  • Air Bags (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK516385A 1984-03-09 1985-11-08 Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter DK516385D0 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/588,122 US4599230A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US06/587,983 US4599231A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
PCT/US1985/000360 WO1985004103A1 (en) 1984-03-09 1985-03-06 Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants

Publications (2)

Publication Number Publication Date
DK516385A true DK516385A (da) 1985-11-08
DK516385D0 DK516385D0 (da) 1985-11-08

Family

ID=27080174

Family Applications (1)

Application Number Title Priority Date Filing Date
DK516385A DK516385D0 (da) 1984-03-09 1985-11-08 Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter

Country Status (11)

Country Link
EP (1) EP0155146B1 (da)
AT (1) ATE82135T1 (da)
AU (2) AU579148B2 (da)
CA (1) CA1253069A (da)
DE (1) DE3586801D1 (da)
DK (1) DK516385D0 (da)
FI (1) FI84558C (da)
IL (3) IL74545A (da)
NO (1) NO167359C (da)
NZ (2) NZ211356A (da)
WO (1) WO1985004103A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
AU617292B2 (en) * 1986-06-20 1991-11-28 Scripps Clinic And Research Foundation T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen
US6222020B1 (en) * 1987-01-07 2001-04-24 Imperial Cancer Research Technology Limited Antigens derived from the core protein of the human mammary epithelial mucin
EP0293201A3 (en) * 1987-05-26 1990-02-28 The Wistar Institute Method of vaccination for hepatitis b virus
EP0300213A1 (en) * 1987-06-22 1989-01-25 Hexal-Pharma Gentechnik GmbH & Co. KG Hepatitis a viral peptide particle immunogens
JPH03500408A (ja) * 1987-09-04 1991-01-31 ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ 増強された安定性を有するペプチド複合体
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
GB9325772D0 (en) * 1993-12-16 1994-02-16 Smithkline Beecham Biolog Novel compounds
CA2251904A1 (en) * 1996-04-18 1997-10-23 Abbott Laboratories An antigenic epitope of the a determinant of hepatitis b surface antigen and uses thereof
CA2266656A1 (en) 1996-09-17 1998-03-26 Chiron Corporation Compositions and methods for treating intracellular diseases
JP2001508054A (ja) * 1996-12-30 2001-06-19 イノジェネティックス・ナムローゼ・フェンノートシャップ HBsAg由来アネキシンV結合ポリペプチドおよびその使用
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
ES2330904B1 (es) 2005-09-21 2010-09-23 Fundacio Centre De Recerca En Sanitat Animal Polinucleotidos de haemophilus parasuis y su uso.
ES2709176T3 (es) 2006-08-11 2019-04-15 Life Sciences Res Partners Vzw Péptidos inmunogénicos y su uso en trastornos inmunitarios
EP2719396B1 (en) 2008-02-14 2017-06-21 Life Sciences Research Partners VZW Immunotherapy targeting intracellular pathogens
EP2247306B1 (en) 2008-02-14 2018-04-18 Life Sciences Research Partners VZW Immunogenic control of tumours and tumour cells
ES2869155T3 (es) 2010-11-25 2021-10-25 Imnate Sarl Péptidos inmunogénicos para su uso en la prevención y/o tratamiento de enfermedades infecciosas, enfermedades autoinmunitarias, respuestas inmunitarias a alofactores, enfermedades alérgicas, tumores, rechazo de injerto y respuestas inmunitarias contra vectores virales usados para terapia génica o vacunación génica
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
JP6440259B2 (ja) * 2012-06-11 2018-12-19 シャアメン ユニバーシティ Hbv感染及び関連疾患を処置するためのポリペプチド及び抗体
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
EP3352782B1 (en) 2015-09-25 2021-03-31 ImCyse SA Improved methods and compounds for eliminating immune responses to therapeutic agents
KR20220132023A (ko) 2016-04-19 2022-09-29 임시스 에스에이 신규 면역원성 CD1d 결합 펩티드
TWI728228B (zh) 2017-02-17 2021-05-21 廈門大學 一種用於展示目的多肽的多肽載體及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
DK171727B1 (da) * 1978-12-22 1997-04-14 Biogen Inc Rekombinante hepatitis B virus DNA-molekyler, værtsorganismer transformeret hermed, HBV-antigenspecifikke polypeptider, DNA-sekvenser kodende for HBV-antigenspecifikke polypeptider, metoder til påvisning af hepatitis B virus-antistoffer, metoder til fremstilling af nævnte DNA-molekyler, fremgangsmåder til fremstilling af nævnte polypeptider og midler til påvisning af HBV-infektion
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
IL61904A (en) * 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
DE3275998D1 (en) * 1981-12-22 1987-05-14 Baylor College Medicine Immunological composition and method for hepatitis b virus
US4483793A (en) * 1982-10-04 1984-11-20 The Regents Of The University Of California Dimeric oligopeptides as heptenic epitopic sites for hepatitis
JPS5974985A (ja) * 1982-10-19 1984-04-27 Takeda Chem Ind Ltd 新規dna
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids

Also Published As

Publication number Publication date
IL74545A (en) 1990-11-05
IL90035A (en) 1990-11-05
ATE82135T1 (de) 1992-11-15
EP0155146A2 (en) 1985-09-18
AU579148B2 (en) 1988-11-17
NO167359B (no) 1991-07-22
IL90035A0 (en) 1989-12-15
AU2682388A (en) 1989-05-25
NZ211356A (en) 1990-07-26
EP0155146B1 (en) 1992-11-11
FI854396L (fi) 1985-11-07
FI854396A0 (fi) 1985-11-07
IL74545A0 (en) 1985-06-30
EP0155146A3 (en) 1988-01-20
NO854460L (no) 1986-01-08
AU623106B2 (en) 1992-05-07
CA1253069A (en) 1989-04-25
NO167359C (no) 1991-10-30
NZ227731A (en) 1990-07-26
DE3586801D1 (de) 1992-12-17
FI84558B (fi) 1991-09-13
AU4115985A (en) 1985-10-11
WO1985004103A1 (en) 1985-09-26
DK516385D0 (da) 1985-11-08
FI84558C (fi) 1991-12-27

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AHB Application shelved due to non-payment