ATE82266T1 - 2,6-bis(chlormethyloxycarbonyloxymethyl)pyridin - Google Patents

2,6-bis(chlormethyloxycarbonyloxymethyl)pyridin

Info

Publication number: ATE82266T1
Authority: AT; Austria
Prior art keywords: bis; pyridine; chlormethyloxycarbonyloxymethyl; preparation; pyridinolcarbamate
Prior art date: 1986-08-22

Application number

AT87307408T

Other languages

English (en)

Inventor

Jozsef Toth

Mate Kovatsits

Laszlo Csutoras

Gabor Szabo

Sandor Goeroeg

Ferenc Trischler

Sandor Holly

Erzsebet Nee Czinege Francsics

Bela Losonczi

Gabor Havasi

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-22

Filing date

1987-08-21

Publication date

1992-11-15

1987-08-21 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1992-11-15 Application granted granted Critical

1992-11-15 Publication of ATE82266T1 publication Critical patent/ATE82266T1/de

Links

OPQIGZYBALLUFI-UHFFFAOYSA-N [6-(chloromethoxycarbonyloxymethyl)pyridin-2-yl]methyl chloromethyl carbonate Chemical compound ClCOC(=O)OCC1=CC=CC(COC(=O)OCCl)=N1 OPQIGZYBALLUFI-UHFFFAOYSA-N 0.000 title abstract 2
YEKQSSHBERGOJK-UHFFFAOYSA-N Pyricarbate Chemical compound CNC(=O)OCC1=CC=CC(COC(=O)NC)=N1 YEKQSSHBERGOJK-UHFFFAOYSA-N 0.000 abstract 1
LFQYNSVRPGADOZ-UHFFFAOYSA-N [6-(hydroxymethyl)pyridin-2-yl]methanol;methylcarbamic acid Chemical compound CNC(O)=O.CNC(O)=O.OCC1=CC=CC(CO)=N1 LFQYNSVRPGADOZ-UHFFFAOYSA-N 0.000 abstract 1
230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229940070851 pyridinolcarbamate Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Fats And Perfumes (AREA)

AT87307408T 1986-08-22 1987-08-21 2,6-bis(chlormethyloxycarbonyloxymethyl)pyridin ATE82266T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU863654A HU197306B (en)	1986-08-22	1986-08-22	Process for producing new 2,6-di/hydroxy-methyl/-pyridine-bis/alpha-chloro-methyl-carbamate/
EP19870307408 EP0258009B1 (de)	1986-08-22	1987-08-21	2,6-Bis(chlormethyloxycarbonyloxymethyl)pyridin

Publications (1)

Publication Number	Publication Date
ATE82266T1 true ATE82266T1 (de)	1992-11-15

Family

ID=10964932

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT87307408T ATE82266T1 (de)	1986-08-22	1987-08-21	2,6-bis(chlormethyloxycarbonyloxymethyl)pyridin

Country Status (11)

Country	Link
US (1)	US4764613A (de)
EP (1)	EP0258009B1 (de)
JP (1)	JPS63101362A (de)
AT (1)	ATE82266T1 (de)
CA (1)	CA1304091C (de)
DE (1)	DE3782585T2 (de)
DK (1)	DK437787A (de)
ES (1)	ES2052571T3 (de)
FI (1)	FI873251A7 (de)
HU (1)	HU197306B (de)
SU (1)	SU1510717A3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6127529A (en) *	1988-06-29	2000-10-03	Wallac Oy	Metal-chelating 2,6-disubstituted pyridine compounds and their use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH484134A (de) *	1966-03-21	1970-01-15	Banyu Pharma Co Ltd	Verfahren zur Herstellung von 2,6-Pyridindimethanol-bis-carbamat-Derivaten
DE3604873A1 (de) *	1986-02-15	1987-08-20	Basf Ag	Verfahren zur herstellung von 2,6-bis (hydroxymethyl)-pyridin-2,6-bis-(n-methylcarbamat)

1986
- 1986-08-22 HU HU863654A patent/HU197306B/hu not_active IP Right Cessation
1987
- 1987-07-24 FI FI873251A patent/FI873251A7/fi not_active Application Discontinuation
- 1987-08-21 CA CA000545124A patent/CA1304091C/en not_active Expired - Lifetime
- 1987-08-21 SU SU874203225A patent/SU1510717A3/ru active
- 1987-08-21 AT AT87307408T patent/ATE82266T1/de not_active IP Right Cessation
- 1987-08-21 EP EP19870307408 patent/EP0258009B1/de not_active Expired - Lifetime
- 1987-08-21 JP JP62206596A patent/JPS63101362A/ja active Pending
- 1987-08-21 DE DE8787307408T patent/DE3782585T2/de not_active Expired - Fee Related
- 1987-08-21 ES ES87307408T patent/ES2052571T3/es not_active Expired - Lifetime
- 1987-08-21 DK DK437787A patent/DK437787A/da not_active Application Discontinuation
- 1987-08-24 US US07/088,875 patent/US4764613A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HU197306B (en)	1989-03-28
DK437787D0 (da)	1987-08-21
DK437787A (da)	1988-02-23
DE3782585D1 (de)	1992-12-17
CA1304091C (en)	1992-06-23
HUT46308A (en)	1988-10-28
JPS63101362A (ja)	1988-05-06
EP0258009B1 (de)	1992-11-11
EP0258009A3 (en)	1989-04-26
FI873251A0 (fi)	1987-07-24
EP0258009A2 (de)	1988-03-02
SU1510717A3 (ru)	1989-09-23
US4764613A (en)	1988-08-16
DE3782585T2 (de)	1993-04-15
ES2052571T3 (es)	1994-07-16
FI873251A7 (fi)	1988-02-23

Legal Events

Date	Code	Title	Description
1993-04-15	UEP	Publication of translation of european patent specification
1996-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
FI901530A0 (fi)	1990-03-27	Menetelmä immunomoduloivien atsaspiraanien valmistamiseksi
BR8704582A (pt)	1988-04-26	Processo para preparar derivados de piridinacarboxamida
ES8307806A1 (es)	1983-08-01	"procedimiento para la preparacion de 1,2-a piridinas y pirazinas".
ATE21105T1 (de)	1986-08-15	7-oxo-4-thia-1-aza(3.2.0)heptan- und 7-oxo-4-thia-1-aza-(3.2.0)hept-2-en-derivate.
NO894349L (no)	1990-05-03	Tienopyridin-type mevalonolaktoner.
ZA883444B (de)	1988-11-16
FI882358A0 (fi)	1988-05-19	Cykliska antikoagulationspeptider.
DK543987A (da)	1988-04-18	Quinolinbaseret forbindelse, fremgangsmaade til fremstilling heraf samt anticancermiddel omfattende samme
IT8420358A0 (it)	1984-04-02	Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti.
ATE58532T1 (de)	1990-12-15	(2-amino-4-aryl-thiazol-5-yl)aethanol, und deren derivate mit diuretischer aktivitaet und verfahren zu deren herstellung.
ATE82266T1 (de)	1992-11-15	2,6-bis(chlormethyloxycarbonyloxymethyl)pyridin
DK638787A (da)	1988-06-06	Anthracyclinderivater, deres fremstilling og anvendelse
NO842345L (no)	1984-12-27	Heksahydropyrrolo(2,1-a)isoquinolin-derivater.
LV5491A3 (lv)	1994-03-10	2-tiazolidinona atvasinajumu iegusanas panemiens
DE3660959D1 (de)	1988-11-24	Benz-trisubstituted 2-aminotetralins
DE69008130D1 (de)	1994-05-19	Glutarsäurederivate und ihre Herstellung.
ES8708226A1 (es)	1987-10-01	Procedimiento para la produccion de derivados de 1,4-dihi- dropiridina
PT84067B (pt)	1989-02-28	Processo de preparacao de novos derivados de pregnano
DE3775905D1 (de)	1992-02-20	Purin-histamin-h1-antagonisten, ihre herstellung und sie enthaltende pharmazeutische praeparate.
ES541540A0 (es)	1986-12-01	Un metodo de preparar un derivado de n-(piridina sustituida en posicion 6)-2-carbonil-histidina sustituida en posicion 3