ATE82968T1 - Hemmung vom 5-lipoxygenase-weg. - Google Patents

Hemmung vom 5-lipoxygenase-weg.

Info

Publication number
ATE82968T1
ATE82968T1 AT86309673T AT86309673T ATE82968T1 AT E82968 T1 ATE82968 T1 AT E82968T1 AT 86309673 T AT86309673 T AT 86309673T AT 86309673 T AT86309673 T AT 86309673T AT E82968 T1 ATE82968 T1 AT E82968T1
Authority
AT
Austria
Prior art keywords
inhibition
lipoxygenase pathway
lipoxygenase
pathway
diaryl
Prior art date
Application number
AT86309673T
Other languages
English (en)
Inventor
Paul Elliot Bender
Nabil Hanna
Don Edgar Griswold
Henry Martin Sarau
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE82968T1 publication Critical patent/ATE82968T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT86309673T 1985-12-12 1986-12-11 Hemmung vom 5-lipoxygenase-weg. ATE82968T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80839585A 1985-12-12 1985-12-12
US06/856,927 US4686231A (en) 1985-12-12 1986-04-28 Inhibition of 5-lipoxygenase products
EP86309673A EP0236628B1 (de) 1985-12-12 1986-12-11 Hemmung vom 5-Lipoxygenase-Weg

Publications (1)

Publication Number Publication Date
ATE82968T1 true ATE82968T1 (de) 1992-12-15

Family

ID=27123119

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86309673T ATE82968T1 (de) 1985-12-12 1986-12-11 Hemmung vom 5-lipoxygenase-weg.

Country Status (7)

Country Link
US (1) US4686231A (de)
EP (1) EP0236628B1 (de)
AT (1) ATE82968T1 (de)
AU (1) AU586907B2 (de)
DE (1) DE3687224T2 (de)
DK (1) DK593886A (de)
PT (1) PT83902B (de)

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US20030050330A1 (en) * 1997-01-10 2003-03-13 G.D. Searle & Co. 4,5-subtstituted imdazolyl compounds for the treatment of inflammation
US5929076A (en) * 1997-01-10 1999-07-27 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
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EP1023066A4 (de) 1997-06-13 2001-05-23 Smithkline Beecham Corp Neue pyrazole- und pyrazoline- substituierte verbindung
AU8154998A (en) 1997-06-19 1999-01-04 Smithkline Beecham Corporation Novel aryloxy substituted pyrimidine imidazole compounds
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US7301021B2 (en) * 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
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US6489325B1 (en) 1998-07-01 2002-12-03 Smithkline Beecham Corporation Substituted imidazole compounds
US6251914B1 (en) 1997-07-02 2001-06-26 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
US6362193B1 (en) 1997-10-08 2002-03-26 Smithkline Beecham Corporation Cycloalkenyl substituted compounds
AU1924699A (en) 1997-12-19 1999-07-12 Smithkline Beecham Corporation Compounds of heteroaryl substituted imidazole, their pharmaceutical compositionsand uses
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US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
US6599910B1 (en) * 1998-08-20 2003-07-29 Smithkline Beecham Corporation Substituted triazole compounds
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US6759410B1 (en) * 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
ES2249309T3 (es) 1999-11-23 2006-04-01 Smithkline Beecham Corp Compuestos de 3,4-dihidro-(1h)quinazolin-2-ona como inhibidores de csbp/p39 kinasa.
ES2230171T3 (es) 1999-11-23 2005-05-01 Smithkline Beecham Corporation Compuestos 3,4-dihidro-(1h)quinazolin-2-ona como inhibidores de csbp/p38 quinasa.
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US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
US7329401B2 (en) * 2002-04-15 2008-02-12 The Regents Of The University Of California Cyclooxygenase-2 selective agents useful as imaging probes and related methods
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Also Published As

Publication number Publication date
DK593886A (da) 1987-06-13
US4686231A (en) 1987-08-11
AU6645286A (en) 1987-06-18
DE3687224D1 (de) 1993-01-14
EP0236628B1 (de) 1992-12-02
PT83902B (en) 1988-10-31
DK593886D0 (da) 1986-12-10
AU586907B2 (en) 1989-07-27
EP0236628A1 (de) 1987-09-16
PT83902A (en) 1987-01-01
DE3687224T2 (de) 1993-04-08

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