ATE83667T1 - Stabilisierte kalcitoninzubereitung. - Google Patents

Stabilisierte kalcitoninzubereitung.

Info

Publication number: ATE83667T1
Authority: AT; Austria
Prior art keywords: kalcitonin; stabilized; preparation; calcitonins; pharmaceutical composition
Prior art date: 1989-05-23

Application number

AT90305542T

Other languages

English (en)

Inventor

Hideki Kobayashi

Seiji Mochizuki

Yuji Makino

Yoshiki Suzuki

Original Assignee

Teijin Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-23

Filing date

1990-05-22

Publication date

1993-01-15

1990-05-22 Application filed by Teijin Ltd filed Critical Teijin Ltd

1993-01-15 Application granted granted Critical

1993-01-15 Publication of ATE83667T1 publication Critical patent/ATE83667T1/de

Links

102000055006 Calcitonin Human genes 0.000 abstract 1
108060001064 Calcitonin Proteins 0.000 abstract 1
PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 1
229960004015 calcitonin Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Zoology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Organic Chemistry (AREA)
Otolaryngology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT90305542T 1989-05-23 1990-05-22 Stabilisierte kalcitoninzubereitung. ATE83667T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP1127743A JP2514249B2 (ja)	1989-05-23	1989-05-23	安定化されたカルシトニン類医薬組成物

Publications (1)

Publication Number	Publication Date
ATE83667T1 true ATE83667T1 (de)	1993-01-15

Family

ID=14967589

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90305542T ATE83667T1 (de)	1989-05-23	1990-05-22	Stabilisierte kalcitoninzubereitung.

Country Status (10)

Country	Link
US (1)	US5211950A (de)
EP (1)	EP0399781B1 (de)
JP (1)	JP2514249B2 (de)
KR (1)	KR950004697B1 (de)
AT (1)	ATE83667T1 (de)
AU (1)	AU635740B2 (de)
CA (1)	CA2017285C (de)
DE (1)	DE69000640T2 (de)
DK (1)	DK0399781T3 (de)
ES (1)	ES2053109T3 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0489217A1 (de) *	1990-12-05	1992-06-10	Dr. A. Tosi Farmaceutici S.R.L.	Calcitoninzusammensetzungen zur intranasalen Verabreichung
JP3179538B2 (ja) *	1990-12-11	2001-06-25	ノバルティスアクチエンゲゼルシャフト	安定なヒトカルシトニンの水性溶液
IT1244500B (it) *	1991-03-21	1994-07-15	Pulitzer Italiana	Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana
US5571788A (en) *	1991-12-09	1996-11-05	Ciba-Geigy Corporation	Stable calcitonin pharmaceutical compositions
US5482931A (en) *	1993-06-29	1996-01-09	Ferring Ab	Stabilized pharmaceutical peptide compositions
US5904935A (en) *	1995-06-07	1999-05-18	Alza Corporation	Peptide/protein suspending formulations
GB9623205D0 (en) *	1996-11-07	1997-01-08	Eurand Int	Novel pharmaceutical compositions
US6228836B1 (en)	1997-04-14	2001-05-08	Mitsubishi-Tokyo Pharmaceuticals, Inc.	Permucous preparation
US7402559B2 (en) *	1999-03-24	2008-07-22	Msh Pharma, Incorporated	Composition and method of treatment for urogenital conditions
CN1198611C (zh)	1999-09-17	2005-04-27	第一三得利制药株式会社	药物抗菌剂组合物
WO2004084859A2 (en)	2003-03-21	2004-10-07	Nastech Pharmaceutical Company Inc.	Nasal calcitonin formulations containing chlorobutanol
AU2003901515A0 (en) *	2003-04-02	2003-04-17	Norika Holdings	Sterilisation process for pharmaceutical product
US7648965B2 (en) *	2004-05-14	2010-01-19	Unigene Laboratories Inc.	Method for fostering bone formation and preservation
US9511144B2 (en)	2013-03-14	2016-12-06	The Proctor & Gamble Company	Cosmetic compositions and methods providing enhanced penetration of skin care actives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2364659A1 (fr) *	1976-09-21	1978-04-14	Commissariat Energie Atomique	Medicament antagoniste de l'action de la gastrine et des polypeptides apparentes
US4241051A (en) *	1977-11-04	1980-12-23	Christie Robert B	Calcitonin
US4476116A (en) *	1982-12-10	1984-10-09	Syntex (U.S.A.) Inc.	Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
AU572815B2 (en) *	1982-12-29	1988-05-19	Armour Pharmaceutical Company	Pharmaceutical calcitonin compositions for intranasal application
US4663309A (en) *	1983-06-29	1987-05-05	University Patents, Inc.	Novel peptide hormones with calcitonin-like activity
JPS61267528A (ja) *	1984-11-26	1986-11-27	Yamanouchi Pharmaceut Co Ltd	吸収促進剤を含有するカルシトニン経鼻剤
JPS61194034A (ja) *	1985-02-25	1986-08-28	Teijin Ltd	経鼻投与用粉末状組成物
IT1204400B (it) *	1986-06-20	1989-03-01	Sclavo Spa	Composizioni farmaceutiche contenente una calcitonina
IT1222734B (it) *	1987-09-25	1990-09-12	Scalvo S P A	Formulaziopne farmaceutiche e forme di dosaggio per la somminaistarzione rettale di calcitonina

1989
- 1989-05-23 JP JP1127743A patent/JP2514249B2/ja not_active Expired - Fee Related
1990
- 1990-05-22 CA CA002017285A patent/CA2017285C/en not_active Expired - Lifetime
- 1990-05-22 AU AU55802/90A patent/AU635740B2/en not_active Ceased
- 1990-05-22 ES ES90305542T patent/ES2053109T3/es not_active Expired - Lifetime
- 1990-05-22 DE DE9090305542T patent/DE69000640T2/de not_active Expired - Fee Related
- 1990-05-22 EP EP90305542A patent/EP0399781B1/de not_active Expired - Lifetime
- 1990-05-22 DK DK90305542.4T patent/DK0399781T3/da active
- 1990-05-22 AT AT90305542T patent/ATE83667T1/de not_active IP Right Cessation
- 1990-05-23 KR KR1019900007438A patent/KR950004697B1/ko not_active Expired - Fee Related
- 1990-05-23 US US07/527,461 patent/US5211950A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH02306921A (ja)	1990-12-20
JP2514249B2 (ja)	1996-07-10
CA2017285A1 (en)	1990-11-23
AU5580290A (en)	1990-11-29
US5211950A (en)	1993-05-18
DE69000640D1 (de)	1993-02-04
CA2017285C (en)	1996-12-10
DE69000640T2 (de)	1993-04-22
KR950004697B1 (ko)	1995-05-04
AU635740B2 (en)	1993-04-01
ES2053109T3 (es)	1994-07-16
EP0399781B1 (de)	1992-12-23
EP0399781A1 (de)	1990-11-28
KR900017609A (ko)	1990-12-19
DK0399781T3 (da)	1993-02-01

Legal Events

Date	Code	Title	Description
1993-06-15	UEP	Publication of translation of european patent specification
2010-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0399781T3 (da)	1993-02-01	Stabiliseret calcitoninpræparat
DE69004731D1 (de)	1994-01-05	Hilfsmittel enthaltende verdünnbare Formulierungen von Nachlaufherbiziden.
ATE46080T1 (de)	1989-09-15	Pharmazeutische komposition.
FI943563L (fi)	1994-07-29	Uusia biologisesti aktiivisia polypeptidejä, niiden valmistus ja niitä sisältävä farmaseuttinen koostumus
DK151985A (da)	1985-10-07	Humant fysiologisk aktivt polypeptid
FI916077A7 (fi)	1991-12-20	Glykosyloimattomia ihmisen interleukiini 3:n proteiinianalogeja
EP0169392A3 (de)	1986-11-05	Triazolobenzodiazepine und diese enthaltende Arzneimittel
IT1231509B (it)	1991-12-07	Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
DE3773295D1 (de)	1991-10-31	Homogene rekombinante immun-interferon-fragmente und diese enthaltende pharmazeutische zusammensetzungen.
FI863078A0 (fi)	1986-07-28	Kontinuerligt frigoerande peptidkompositioner.
IT8919637A0 (it)	1989-03-03	Isomero otticamente attivo della cloperastina avente attivita' antitussiva, processo per la sua preparazione e composizioni farmaceutiche che lo contengono.
IT8520234A0 (it)	1985-04-04	Composizione farmaceutiche adattivita' dopominergica.
SE8800461D0 (sv)	1988-02-11	Farmaceutisk komposition
IT8819731A0 (it)	1988-03-11	Composizioni farmaceutiche contenenti timosina alfa 1.
IT8221659A0 (it)	1982-06-02	Composizione terapeutica adattivita' antibatterica a base di una frazione estratta da fiori di camomilla e processo per lapreparazione di detta frazione.
IT1228803B (it)	1991-07-03	Struttura per giochi di abilita' combinatoria.
IT1215261B (it)	1990-01-31	Composizioni farmaceutiche adattivita' antigalattopoietica.
IT8723090A0 (it)	1987-12-18	Composizione cementizia a bassa viscosita'
IT8220251A0 (it)	1982-03-18	Composizione farmaceutica adattivita' immunomodulatrice.
IT8622051A0 (it)	1986-10-17	Composizioni farmaceutiche adattivita' cicatrizzante.
IT1205109B (it)	1989-03-15	Composizioni farmaceutiche ad attivita' immunomodulante
IT8719184A0 (it)	1987-01-28	Gastroduodenale. composizioni farmaceutiche ad azione sinergica antisecretoria per la cicatrizzazione dell'ulcera
IT8919283A0 (it)	1989-02-01	Composizione farmaceutica comprendente come ingrediente attivo 3 n piperidinometil azino metilrifamicina s.
IT8921302A0 (it)	1989-07-25	Composizione conservabile per l'alimentazione di giovani mammiferi e procedimento per la sua preparazione.
IT1228963B (it)	1991-07-11	Tavolo ad elevata flessibilita' di composizione.