ATE84300T1 - Aminosalze von alkan-1,n-dicarbonsaeure-mono-(2sulfato-|thyl)amiden. - Google Patents

Aminosalze von alkan-1,n-dicarbonsaeure-mono-(2sulfato-|thyl)amiden.

Info

Publication number
ATE84300T1
ATE84300T1 AT88906733T AT88906733T ATE84300T1 AT E84300 T1 ATE84300 T1 AT E84300T1 AT 88906733 T AT88906733 T AT 88906733T AT 88906733 T AT88906733 T AT 88906733T AT E84300 T1 ATE84300 T1 AT E84300T1
Authority
AT
Austria
Prior art keywords
amides
acid mono
2sulfato
alkan
thyl
Prior art date
Application number
AT88906733T
Other languages
English (en)
Inventor
Bruce A Pearlman
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE84300T1 publication Critical patent/ATE84300T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/02Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/34Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfuric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT88906733T 1987-07-16 1988-07-01 Aminosalze von alkan-1,n-dicarbonsaeure-mono-(2sulfato-|thyl)amiden. ATE84300T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7438187A 1987-07-16 1987-07-16
PCT/US1988/002181 WO1989000558A1 (en) 1987-07-16 1988-07-01 AMINE SALTS OF ALKANE-1,n-DICARBOXYLIC ACID MONO-(2-SULFATO-ETHYL)AMIDES
EP88906733A EP0374166B1 (de) 1987-07-16 1988-07-01 Aminosalze von alkan-1,n-dicarbonsäure-mono-(2-sulfato-äthyl)amiden

Publications (1)

Publication Number Publication Date
ATE84300T1 true ATE84300T1 (de) 1993-01-15

Family

ID=22119253

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88906733T ATE84300T1 (de) 1987-07-16 1988-07-01 Aminosalze von alkan-1,n-dicarbonsaeure-mono-(2sulfato-|thyl)amiden.

Country Status (8)

Country Link
EP (1) EP0374166B1 (de)
JP (1) JP2549724B2 (de)
KR (1) KR890701552A (de)
AT (1) ATE84300T1 (de)
AU (1) AU2138988A (de)
DE (1) DE3877361T2 (de)
HK (1) HK36096A (de)
WO (1) WO1989000558A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK404879A (da) * 1978-10-04 1980-04-05 Schering Ag Kortikoid-21-sulfopropionater og deres salte fremgangsmaade til deres fremstilling og farmaceutiske praeparater indeholdende disse forbindelser
US4456602A (en) * 1982-08-23 1984-06-26 The Upjohn Company Amine containing ester prodrugs of corticosteroids
US4472392A (en) * 1983-01-21 1984-09-18 The Upjohn Company Sulfonate containing ester prodrugs of corticosteroids
US4469689A (en) * 1983-03-30 1984-09-04 The Upjohn Company Sulfonate containing ester prodrugs of corticosteroids
CA1310009C (en) * 1984-03-28 1992-11-10 John Mark Braughler Ester prodrugs of steroids

Also Published As

Publication number Publication date
JP2549724B2 (ja) 1996-10-30
EP0374166A1 (de) 1990-06-27
EP0374166B1 (de) 1993-01-07
DE3877361D1 (de) 1993-02-18
WO1989000558A1 (en) 1989-01-26
HK36096A (en) 1996-03-08
DE3877361T2 (de) 1993-05-13
JPH02504276A (ja) 1990-12-06
AU2138988A (en) 1989-02-13
KR890701552A (ko) 1989-12-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee