ATE85083T1 - Verfahren zur enzymatischen trennung der optischen isomere von racemischen oxazolidinonderivaten. - Google Patents
Verfahren zur enzymatischen trennung der optischen isomere von racemischen oxazolidinonderivaten.Info
- Publication number
- ATE85083T1 ATE85083T1 AT87311519T AT87311519T ATE85083T1 AT E85083 T1 ATE85083 T1 AT E85083T1 AT 87311519 T AT87311519 T AT 87311519T AT 87311519 T AT87311519 T AT 87311519T AT E85083 T1 ATE85083 T1 AT E85083T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- alkyl
- branched
- straight
- group
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000003287 optical effect Effects 0.000 title abstract 2
- 238000000926 separation method Methods 0.000 title abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000003837 (C1-C20) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- 108010093096 Immobilized Enzymes Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 oxazolidinone compound Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT22884/86A IT1198266B (it) | 1986-12-30 | 1986-12-30 | Processo per la separazione enzimatica degli isomeri ottici di derivati ossazolidinonici racemi |
| EP87311519A EP0274277B1 (de) | 1986-12-30 | 1987-12-30 | Verfahren zur enzymatischen Trennung der optischen Isomere von racemischen Oxazolidinon-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE85083T1 true ATE85083T1 (de) | 1993-02-15 |
Family
ID=11201524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87311519T ATE85083T1 (de) | 1986-12-30 | 1987-12-30 | Verfahren zur enzymatischen trennung der optischen isomere von racemischen oxazolidinonderivaten. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4933290A (de) |
| EP (1) | EP0274277B1 (de) |
| JP (1) | JPS63245686A (de) |
| KR (1) | KR880007742A (de) |
| AT (1) | ATE85083T1 (de) |
| AU (1) | AU608798B2 (de) |
| BR (1) | BR8707155A (de) |
| CA (1) | CA1294910C (de) |
| DE (1) | DE3783901T2 (de) |
| ES (1) | ES2053572T3 (de) |
| IL (1) | IL84921A (de) |
| IT (1) | IT1198266B (de) |
| ZA (1) | ZA879669B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE87036T1 (de) * | 1986-11-28 | 1993-04-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von carbonsaeureestern. |
| GB8728064D0 (en) * | 1987-12-01 | 1988-01-06 | Shell Int Research | Process for preparation of substituted phenoxy propanoic acids |
| US5061629A (en) * | 1988-01-26 | 1991-10-29 | Hoffman-La Roche Inc. | Production of 2-hydroxy substituted arylalkanoic acids and esters by enzymatic hydrolysis |
| US5037747A (en) * | 1988-01-26 | 1991-08-06 | Hoffmann-La Roche Inc. | Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis |
| IT1216743B (it) * | 1988-02-10 | 1990-03-08 | Donegani Guido Ist | Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi. |
| US5106750A (en) * | 1988-08-30 | 1992-04-21 | G. D. Searle & Co. | Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents |
| WO1993022451A1 (en) * | 1992-05-01 | 1993-11-11 | Cognis, Inc. | PROCESS OF PREPARING ENRICHED ENANTIOMERS OF GLYCEROL CARBONATE AND DERIVATIVES THEREOF FOR SYNTHESIS OF β-BLOCKERS |
| JPH06125788A (ja) * | 1992-05-29 | 1994-05-10 | Kureha Chem Ind Co Ltd | 光学活性１，２−ジオール誘導体の製造方法 |
| BE1007297A3 (nl) * | 1993-07-19 | 1995-05-09 | Dsm Nv | Werkwijze voor de bereiding van optisch aktieve alcoholen en esters, en alcoholen en esters toegepast en bereid in dergelijke werkwijzen. |
| US5942527A (en) * | 1997-08-27 | 1999-08-24 | K & K Biosciences, Inc. | Hydrazones, hydrazines, semicarbazones and thiosemicarbazones derived from pyridyl ketones as anticonvulsant drugs and excitatory amino acid antagonists |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5931693A (ja) * | 1982-08-13 | 1984-02-20 | Kanegafuchi Chem Ind Co Ltd | 光学活性オキサゾリジノン誘導体の製造方法 |
| DE3378834D1 (en) * | 1982-08-13 | 1989-02-09 | Kanegafuchi Chemical Ind | Process for production of optically active oxazolidinone derivative |
-
1986
- 1986-12-30 IT IT22884/86A patent/IT1198266B/it active
-
1987
- 1987-12-22 IL IL84921A patent/IL84921A/xx unknown
- 1987-12-23 ZA ZA879669A patent/ZA879669B/xx unknown
- 1987-12-24 US US07/137,721 patent/US4933290A/en not_active Expired - Fee Related
- 1987-12-28 JP JP62330362A patent/JPS63245686A/ja active Pending
- 1987-12-29 CA CA000555529A patent/CA1294910C/en not_active Expired - Lifetime
- 1987-12-30 ES ES87311519T patent/ES2053572T3/es not_active Expired - Lifetime
- 1987-12-30 EP EP87311519A patent/EP0274277B1/de not_active Expired - Lifetime
- 1987-12-30 AT AT87311519T patent/ATE85083T1/de active
- 1987-12-30 AU AU83122/87A patent/AU608798B2/en not_active Ceased
- 1987-12-30 KR KR1019870015476A patent/KR880007742A/ko not_active Withdrawn
- 1987-12-30 BR BR8707155A patent/BR8707155A/pt not_active Application Discontinuation
- 1987-12-30 DE DE8787311519T patent/DE3783901T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0274277A2 (de) | 1988-07-13 |
| CA1294910C (en) | 1992-01-28 |
| EP0274277A3 (en) | 1989-06-14 |
| IT8622884A0 (it) | 1986-12-30 |
| DE3783901T2 (de) | 1993-05-19 |
| IT8622884A1 (it) | 1988-06-30 |
| US4933290A (en) | 1990-06-12 |
| ES2053572T3 (es) | 1994-08-01 |
| IL84921A (en) | 1992-03-29 |
| KR880007742A (ko) | 1988-08-29 |
| BR8707155A (pt) | 1988-08-02 |
| IT1198266B (it) | 1988-12-21 |
| EP0274277B1 (de) | 1993-01-27 |
| AU608798B2 (en) | 1991-04-18 |
| DE3783901D1 (de) | 1993-03-11 |
| ZA879669B (en) | 1988-06-23 |
| JPS63245686A (ja) | 1988-10-12 |
| IL84921A0 (en) | 1988-06-30 |
| AU8312287A (en) | 1988-06-30 |
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