ATE85345T1 - Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. - Google Patents

Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.

Info

Publication number: ATE85345T1
Authority: AT; Austria
Prior art keywords: fragment; anf; cdd; arg; ser
Prior art date: 1987-03-02

Application number

AT88901838T

Other languages

English (en)

Inventor

Wolf-Georg Forssmann

Jeanette M Alt

Gerhard Becker

Franz Herbst

Original Assignee

Forssmann Wolf Georg

Bissendorf Peptide Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-02

Filing date

1988-02-27

Publication date

1993-02-15

1987-03-02 Priority claimed from DE19873706731 external-priority patent/DE3706731A1/de

1987-05-22 Priority claimed from DE19873717329 external-priority patent/DE3717329A1/de

1988-02-27 Application filed by Forssmann Wolf Georg, Bissendorf Peptide Gmbh filed Critical Forssmann Wolf Georg

1993-02-15 Application granted granted Critical

1993-02-15 Publication of ATE85345T1 publication Critical patent/ATE85345T1/de

Links

239000012634 fragment Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
102400001279 Urodilatin Human genes 0.000 abstract 4
IUCCYQIEZNQWRS-DWWHXVEHSA-N ularitide Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 IUCCYQIEZNQWRS-DWWHXVEHSA-N 0.000 abstract 4
108010033276 Peptide Fragments Proteins 0.000 abstract 3
102000007079 Peptide Fragments Human genes 0.000 abstract 3
150000001413 amino acids Chemical group 0.000 abstract 3
108010001957 Ularitide Proteins 0.000 abstract 2
101800001849 Urodilatin Proteins 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
210000003734 kidney Anatomy 0.000 abstract 1
238000011084 recovery Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Neurology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Ophthalmology & Optometry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Polyesters Or Polycarbonates (AREA)

AT88901838T 1987-03-02 1988-02-27 Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. ATE85345T1 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
DE19873706731 DE3706731A1 (de)	1987-03-02	1987-03-02	Neues cardiodilatinfragment und verfahren zur gewinnung von cardiodilatinfragmenten
DE19873717329 DE3717329A1 (de)	1987-05-22	1987-05-22	Neues cardiodilatinfragment, verfahren zu seiner gewinnung und seine verwendung
DE3741641		1987-12-09
EP88901838A EP0349545B1 (de)	1987-03-02	1988-02-27	Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung
PCT/EP1988/000144 WO1988006596A1 (en)	1987-03-02	1988-02-27	New cardiodilatin fragment, process for preparing same and use thereof

Publications (1)

Publication Number	Publication Date
ATE85345T1 true ATE85345T1 (de)	1993-02-15

Family

ID=27195544

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88901838T ATE85345T1 (de)	1987-03-02	1988-02-27	Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.

Country Status (7)

Country	Link
EP (1)	EP0349545B1 (de)
JP (1)	JP2819467B2 (de)
AT (1)	ATE85345T1 (de)
AU (1)	AU614738B2 (de)
DE (1)	DE3878231T2 (de)
DK (1)	DK174112B1 (de)
WO (1)	WO1988006596A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5262521A (en) *	1991-06-07	1993-11-16	Sri International	Isolated atrial peptide-degrading enzyme and novel compounds useful as inhibitors thereof
DE4216133A1 (de) *	1992-05-15	1993-11-18	Bissendorf Peptide Gmbh	Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen
US5665704A (en) *	1993-11-12	1997-09-09	Genentech, Inc.	Receptor specific atrial natriuretic peptides
US6525022B1 (en)	1993-11-12	2003-02-25	Genentech, Inc.	Receptor specific atrial natriuretic peptides
US5846932A (en) *	1993-11-12	1998-12-08	Genentech, Inc.	Receptor specific atrial natriuretic peptides
EP0763061B1 (de) *	1994-06-02	2002-10-30	Forssmann, Wolf-Georg, Prof. Dr. med.	Verfahren zur herstellung von cardiodilatin-fragmenten, hochgereinigte cardiodilatin-fragmente und zwischenprodukte zu deren herstellung
DE19535445A1 (de) *	1995-09-23	1997-03-27	Boehringer Mannheim Gmbh	Verfahren zur Herstellung von natriuretischen Peptiden über Streptavidin-Fusionsproteine
JP2000500019A (ja) *	1995-11-16	2000-01-11	ロシュダイアグノスティクスゲゼルシャフトミットベシュレンクテルハフツング	ストレプトアビジン融合タンパク質経由でのペプチドの生産方法
DE19951471A1 (de) *	1999-10-26	2001-05-03	Forssmann Wolf Georg	Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen
DE10116552A1 (de)	2001-04-03	2002-10-10	Abc Armbruster Biochemicals	Verfahren zur Bestimmung der wirksamen Parathormon-Aktivität in einer Probe
EP2510942B1 (de)	2005-04-07	2015-09-02	Cardiorentis AG	Verwendung eines natriuretischen Peptids zur Behandlung von Herzversagen
US8580746B2 (en)	2006-03-30	2013-11-12	Palatin Technologies, Inc.	Amide linkage cyclic natriuretic peptide constructs
MX2008012663A (es)	2006-03-30	2008-10-13	Palatin Technologies Inc	Constructos ciclicos de peptidos natriureticos.
AU2007233123A1 (en)	2006-03-30	2007-10-11	Palatin Technologies, Inc.	Linear natriuretic peptide constructs
EP2185183B1 (de) *	2007-09-11	2016-03-16	Cardiopep Pharma GmbH	Verwendung von natriuretischen peptiden zur behandlung von angioödemen
EP2631247A1 (de)	2012-02-22	2013-08-28	Immundiagnostik AG	Mittel und Verfahren zum Messen des Parathyroid-Hormons bei unter oxidativem Stress leidenden Patienten
EP2775306B1 (de)	2013-03-08	2018-06-27	Immundiagnostik AG	Nicht oxidiertes, biologisch aktives Parathormon zur Bestimmung der Sterblichkeit bei Hämodialysepatienten
US20200371118A1 (en)	2018-01-17	2020-11-26	Immundiagnostik Ag	Biomarker predicting coronary artery diseases
FR3099056B1 (fr) *	2019-07-26	2022-08-12	Univ Rouen Normandie	Utilisation de l’ANP pour détruire les biofilms bactériens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0780907B2 (ja) *	1984-04-19	1995-08-30	シオス・ノバ・インク	新規な心房性ナトリウム尿排泄亢進性及び血管拡張性ポリペプチド
DE3443257A1 (de) *	1984-11-28	1986-05-28	Bissendorf Peptide GmbH, 3002 Wedemark	Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap)

1988
- 1988-02-27 AU AU13481/88A patent/AU614738B2/en not_active Expired
- 1988-02-27 AT AT88901838T patent/ATE85345T1/de not_active IP Right Cessation
- 1988-02-27 DE DE8888901838T patent/DE3878231T2/de not_active Expired - Lifetime
- 1988-02-27 JP JP63502001A patent/JP2819467B2/ja not_active Expired - Lifetime
- 1988-02-27 EP EP88901838A patent/EP0349545B1/de not_active Expired - Lifetime
- 1988-02-27 WO PCT/EP1988/000144 patent/WO1988006596A1/en not_active Ceased
- 1988-11-02 DK DK198806108A patent/DK174112B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3878231T2 (de)	1993-05-27
DK174112B1 (da)	2002-06-24
JP2819467B2 (ja)	1998-10-30
AU1348188A (en)	1988-09-26
DE3878231D1 (de)	1993-03-18
WO1988006596A1 (en)	1988-09-07
EP0349545A1 (de)	1990-01-10
JPH02502636A (ja)	1990-08-23
DK610888D0 (da)	1988-11-02
AU614738B2 (en)	1991-09-12
EP0349545B1 (de)	1993-02-03
DK610888A (da)	1988-11-02

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Legal Events

Date	Code	Title	Description
1993-08-15	UEP	Publication of translation of european patent specification
2003-11-15	REN	Ceased due to non-payment of the annual fee