ATE85345T1 - Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. - Google Patents

Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.

Info

Publication number: ATE85345T1
Authority: AT; Austria
Prior art keywords: fragment; anf; cdd; arg; ser
Prior art date: 1987-03-02

Application number

AT88901838T

Other languages

English (en)

Inventor

Wolf-Georg Forssmann

Jeanette M Alt

Gerhard Becker

Franz Herbst

Original Assignee

Forssmann Wolf Georg

Bissendorf Peptide Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-02

Filing date

1988-02-27

Publication date

1993-02-15

1987-03-02 Priority claimed from DE19873706731 external-priority patent/DE3706731A1/de

1987-05-22 Priority claimed from DE19873717329 external-priority patent/DE3717329A1/de

1988-02-27 Application filed by Forssmann Wolf Georg, Bissendorf Peptide Gmbh filed Critical Forssmann Wolf Georg

1993-02-15 Application granted granted Critical

1993-02-15 Publication of ATE85345T1 publication Critical patent/ATE85345T1/de

Links

239000012634 fragment Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
102400001279 Urodilatin Human genes 0.000 abstract 4
IUCCYQIEZNQWRS-DWWHXVEHSA-N ularitide Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 IUCCYQIEZNQWRS-DWWHXVEHSA-N 0.000 abstract 4
108010033276 Peptide Fragments Proteins 0.000 abstract 3
102000007079 Peptide Fragments Human genes 0.000 abstract 3
150000001413 amino acids Chemical group 0.000 abstract 3
108010001957 Ularitide Proteins 0.000 abstract 2
101800001849 Urodilatin Proteins 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
210000003734 kidney Anatomy 0.000 abstract 1
238000011084 recovery Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Neurology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Ophthalmology & Optometry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

AT88901838T 1987-03-02 1988-02-27 Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. ATE85345T1 (de)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
DE19873706731 DE3706731A1 (de)	1987-03-02	1987-03-02	Neues cardiodilatinfragment und verfahren zur gewinnung von cardiodilatinfragmenten
DE19873717329 DE3717329A1 (de)	1987-05-22	1987-05-22	Neues cardiodilatinfragment, verfahren zu seiner gewinnung und seine verwendung
DE3741641		1987-12-09
PCT/EP1988/000144 WO1988006596A1 (en)	1987-03-02	1988-02-27	New cardiodilatin fragment, process for preparing same and use thereof
EP88901838A EP0349545B1 (de)	1987-03-02	1988-02-27	Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung

Publications (1)

Publication Number	Publication Date
ATE85345T1 true ATE85345T1 (de)	1993-02-15

Family

ID=27195544

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88901838T ATE85345T1 (de)	1987-03-02	1988-02-27	Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.

Country Status (7)

Country	Link
EP (1)	EP0349545B1 (de)
JP (1)	JP2819467B2 (de)
AT (1)	ATE85345T1 (de)
AU (1)	AU614738B2 (de)
DE (1)	DE3878231T2 (de)
DK (1)	DK174112B1 (de)
WO (1)	WO1988006596A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5262521A (en) *	1991-06-07	1993-11-16	Sri International	Isolated atrial peptide-degrading enzyme and novel compounds useful as inhibitors thereof
DE4216133A1 (de) *	1992-05-15	1993-11-18	Bissendorf Peptide Gmbh	Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen
US5665704A (en) *	1993-11-12	1997-09-09	Genentech, Inc.	Receptor specific atrial natriuretic peptides
US6525022B1 (en)	1993-11-12	2003-02-25	Genentech, Inc.	Receptor specific atrial natriuretic peptides
US5846932A (en) *	1993-11-12	1998-12-08	Genentech, Inc.	Receptor specific atrial natriuretic peptides
JPH10500969A (ja) *	1994-06-02	1998-01-27	ベーリンガーマンハイムゲゼルシャフトミットベシュレンクテルハフツング	カルジオジラチンフラグメントの調製方法、高度に精製されたカルジオジラチンフラグメント及びそれらの調製のための中間生成物類
DE19535445A1 (de) *	1995-09-23	1997-03-27	Boehringer Mannheim Gmbh	Verfahren zur Herstellung von natriuretischen Peptiden über Streptavidin-Fusionsproteine
JP2000500019A (ja) *	1995-11-16	2000-01-11	ロシュダイアグノスティクスゲゼルシャフトミットベシュレンクテルハフツング	ストレプトアビジン融合タンパク質経由でのペプチドの生産方法
DE19951471A1 (de) *	1999-10-26	2001-05-03	Forssmann Wolf Georg	Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen
DE10116552A1 (de)	2001-04-03	2002-10-10	Abc Armbruster Biochemicals	Verfahren zur Bestimmung der wirksamen Parathormon-Aktivität in einer Probe
EP2510942B1 (de)	2005-04-07	2015-09-02	Cardiorentis AG	Verwendung eines natriuretischen Peptids zur Behandlung von Herzversagen
US7795221B2 (en)	2006-03-30	2010-09-14	Palatin Technologies, Inc.	Linear natriuretic peptide constructs
KR101434612B1 (ko)	2006-03-30	2014-08-26	팔라틴 테크놀로지스 인코포레이티드	사이클릭 나트륨 이뇨 펩타이드 구조물
US8580746B2 (en)	2006-03-30	2013-11-12	Palatin Technologies, Inc.	Amide linkage cyclic natriuretic peptide constructs
ES2575397T3 (es) *	2007-09-11	2016-06-28	Cardiopep Pharma Gmbh	Uso de péptidos natriuréticos para el tratamiento de síndromes de angioedema
EP2631247A1 (de)	2012-02-22	2013-08-28	Immundiagnostik AG	Mittel und Verfahren zum Messen des Parathyroid-Hormons bei unter oxidativem Stress leidenden Patienten
EP2775306B1 (de)	2013-03-08	2018-06-27	Immundiagnostik AG	Nicht oxidiertes, biologisch aktives Parathormon zur Bestimmung der Sterblichkeit bei Hämodialysepatienten
US20200371118A1 (en)	2018-01-17	2020-11-26	Immundiagnostik Ag	Biomarker predicting coronary artery diseases
FR3099056B1 (fr) *	2019-07-26	2022-08-12	Univ Rouen Normandie	Utilisation de l’ANP pour détruire les biofilms bactériens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE120759T1 (de) *	1984-04-19	1995-04-15	Scios Nova Inc	Atrielle natriumuretische/gefässerweiterende polypeptide.
DE3443257A1 (de) *	1984-11-28	1986-05-28	Bissendorf Peptide GmbH, 3002 Wedemark	Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap)

1988
- 1988-02-27 DE DE8888901838T patent/DE3878231T2/de not_active Expired - Lifetime
- 1988-02-27 AU AU13481/88A patent/AU614738B2/en not_active Expired
- 1988-02-27 EP EP88901838A patent/EP0349545B1/de not_active Expired - Lifetime
- 1988-02-27 JP JP63502001A patent/JP2819467B2/ja not_active Expired - Lifetime
- 1988-02-27 AT AT88901838T patent/ATE85345T1/de not_active IP Right Cessation
- 1988-02-27 WO PCT/EP1988/000144 patent/WO1988006596A1/en not_active Ceased
- 1988-11-02 DK DK198806108A patent/DK174112B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK174112B1 (da)	2002-06-24
JPH02502636A (ja)	1990-08-23
AU1348188A (en)	1988-09-26
DK610888A (da)	1988-11-02
EP0349545B1 (de)	1993-02-03
DE3878231D1 (de)	1993-03-18
EP0349545A1 (de)	1990-01-10
JP2819467B2 (ja)	1998-10-30
DE3878231T2 (de)	1993-05-27
AU614738B2 (en)	1991-09-12
DK610888D0 (da)	1988-11-02
WO1988006596A1 (en)	1988-09-07

Legal Events

Date	Code	Title	Description
1993-08-15	UEP	Publication of translation of european patent specification
2003-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE85345T1 (de)	1993-02-15	Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.
PT93910A (pt)	1991-01-08	Prodesso para a preparacao de uma proteina heterologa mediante secrecao a partir de uma celula
TR199802789T2 (xx)	1999-03-22	Eksendin analoglar� bunlar�n �retimi i�in y�ntemler ve bunlar� i�eren farmas�tik m�stahzarlar.
GEP20033002B (en)	2003-06-25	Osteoprotegerin Binding Protein and Receptors
ATE75483T1 (de)	1992-05-15	Oligonukleotides heilmittel und dessen herstellungsverfahren.
ATE32728T1 (de)	1988-03-15	Modifizierte protease-inhibitoren, verfahren zu ihrer herstellung und daraus bereitete pharmazeutische mittel.
HUT58813A (en)	1992-03-30	Process for producing tissue-plasminogen activator derivative
HUT46061A (en)	1988-09-28	Dna sequences encoding hirudin-like protein and process for producing such proteins
DK162233C (da)	1992-03-16	Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii
ATA309588A (de)	1997-04-15	Neue kristallform von ciclosporin, verfahren zu ihrer herstellung, diese kristallform enthaltende pharmazeutische zusammensetzung und verwendung dieser kristallform
AU617989B2 (en)	1991-12-12	Variants of hirudin, their use and their preparation
SE9501472D0 (sv)	1995-04-21	Truncated IGF-I
DK482185D0 (da)	1985-10-21	Peptider, deres fremstilling og anvendelse som laegemidler
EP0546087A4 (de)	1994-01-05
ES2170144T3 (es)	2002-08-01	Variantes que no se empalman de gp350/220.
KR880011200A (ko)	1988-10-27	텐다미스탵 유도체
ATE6639T1 (de)	1984-03-15	Ein gereinigtes polypeptid, ein verfahren zu dessen herstellung, dessen anwendung und das enthaltende pharmazeutische praeparat.
AR018532A1 (es)	2001-11-28	Proteinas sustancialmente puras que contienen analogos de la beta-lipoproteina (blt); aislados de acidos nucleicos que codifican dichas proteinas yformulaciones farmaceuticas que comprenden las proteinas
BG101846A (en)	1998-07-31	HUMAN DNase I VARIANTS
PT88913A (pt)	1988-12-01	Processo para a preparacao da proteina pp4-x anticoagulante
WO1990003394A3 (fr)	1990-07-12	Nouvelles lymphokines, sequences d'adn codant pour ces lymphokines et compositions pharmaceutiques contenant ces lymphokines
DK0580782T3 (da)	1998-05-04	Anti-HIV-protein, TAP 29, fra Trichosanthes, DNA, som koder derfor, og terapeutiske anvendelser deraf
WO1998036068A3 (en)	1998-10-22	Human p24 vesicle proteins
ATE32066T1 (de)	1988-02-15	Antihypertensive 3-aryl-1,2-benzisoxazolsulfonyl und -sulfinyl-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von medikamenten.
BG101847A (en)	1998-07-31	Human dnase i variants