ATE86661T1 - Lipase und lipasische extrakte, verfahren zur herstellung und therapeutische anwendung. - Google Patents
Lipase und lipasische extrakte, verfahren zur herstellung und therapeutische anwendung.Info
- Publication number
- ATE86661T1 ATE86661T1 AT87401984T AT87401984T ATE86661T1 AT E86661 T1 ATE86661 T1 AT E86661T1 AT 87401984 T AT87401984 T AT 87401984T AT 87401984 T AT87401984 T AT 87401984T AT E86661 T1 ATE86661 T1 AT E86661T1
- Authority
- AT
- Austria
- Prior art keywords
- lipase
- preparation
- extracts
- therapeutic application
- malabsorptions
- Prior art date
Links
- 102000004882 Lipase Human genes 0.000 title abstract 4
- 108090001060 Lipase Proteins 0.000 title abstract 4
- 239000004367 Lipase Substances 0.000 title abstract 4
- 235000019421 lipase Nutrition 0.000 title abstract 4
- 239000000284 extract Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- 206010025476 Malabsorption Diseases 0.000 abstract 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000004255 ion exchange chromatography Methods 0.000 abstract 1
- 239000002808 molecular sieve Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8612996A FR2603804B1 (fr) | 1986-09-17 | 1986-09-17 | Lipases et extraits lipasiques, leur procede de preparation et leur application en therapeutique |
| EP87401984A EP0261016B1 (de) | 1986-09-17 | 1987-09-04 | Lipase und lipasische Extrakte, Verfahren zur Herstellung und therapeutische Anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE86661T1 true ATE86661T1 (de) | 1993-03-15 |
Family
ID=9339032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87401984T ATE86661T1 (de) | 1986-09-17 | 1987-09-04 | Lipase und lipasische extrakte, verfahren zur herstellung und therapeutische anwendung. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5075231A (de) |
| EP (1) | EP0261016B1 (de) |
| JP (1) | JPS6379589A (de) |
| KR (1) | KR960011522B1 (de) |
| AT (1) | ATE86661T1 (de) |
| AU (1) | AU602349B2 (de) |
| CA (1) | CA1308678C (de) |
| DE (1) | DE3784607T2 (de) |
| DK (1) | DK483087A (de) |
| ES (1) | ES2053575T3 (de) |
| FI (1) | FI87232C (de) |
| FR (1) | FR2603804B1 (de) |
| IE (1) | IE59972B1 (de) |
| IS (1) | IS3251A7 (de) |
| NO (1) | NO170316C (de) |
| NZ (1) | NZ221568A (de) |
| ZA (1) | ZA876322B (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2683549B1 (fr) * | 1991-11-13 | 1994-11-18 | Jouveinal Inst Rech | Acides nucleiques codant pour la lipase gastrique de lapin et derives polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques a base de ces derniers. |
| US5998189A (en) * | 1992-12-16 | 1999-12-07 | Warner-Lambert Company | Polypeptide derivatives of dog gastric lipase and pharmaceutical compositions containing same |
| FR2699179B1 (fr) * | 1992-12-16 | 1995-01-06 | Jouveinal Inst Rech | Acides nucléiques codant pour la lipase gastrique de chien et dérivés polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques à base de ces derniers. |
| FR2733249B1 (fr) * | 1995-04-20 | 1997-06-06 | Biocem | Lipase gastrique de chien recombinante et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| JP2000026311A (ja) * | 1998-07-02 | 2000-01-25 | Amano Pharmaceut Co Ltd | 胃排出能亢進剤組成物 |
| US6534300B1 (en) | 1999-09-14 | 2003-03-18 | Genzyme Glycobiology Research Institute, Inc. | Methods for producing highly phosphorylated lysosomal hydrolases |
| US6770468B1 (en) | 1999-09-14 | 2004-08-03 | Genzyme Glycobiology Research Institute, Inc. | Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway |
| WO2001049282A2 (en) * | 2000-01-06 | 2001-07-12 | Martek Biosciences Corporation | Therapeutic preparations of highly unsaturated fatty acids |
| EP1149585A1 (de) * | 2000-04-27 | 2001-10-31 | Warner-Lambert Company | Verwendung einer rekombinanten Lipase aus Magen zur Behandlung der funktionellen Dyspepsia |
| US6800472B2 (en) | 2001-12-21 | 2004-10-05 | Genzyme Glycobiology Research Institute, Inc. | Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase |
| US6905856B2 (en) | 2001-12-21 | 2005-06-14 | Genzyme Glycobiology Research Institute, Inc. | Soluble GlcNAc phosphotransferase |
| DE102005010604B3 (de) * | 2005-03-06 | 2006-07-20 | Lange Uhren Gmbh | Uhr |
| KR100828146B1 (ko) * | 2006-04-28 | 2008-05-08 | 김우식 | 췌장 리파아제의 선택적 추출방법 |
| EP1870649A1 (de) | 2006-06-20 | 2007-12-26 | Octapharma AG | Gefriertocknung zum Erzielen einer bestimmte Restfeuchte durch beschränkte Desorptionsenergiepegeln. |
| DK2079445T3 (en) | 2007-02-20 | 2016-02-15 | Allergan Pharmaceuticals Internat Ltd | Stable digestive compositions |
| EP2214481B1 (de) | 2007-10-15 | 2019-05-01 | United Animal Health, Inc. | Verfahren zur erhöhung der leistung von nachkommen |
| KR20140019292A (ko) | 2010-10-01 | 2014-02-14 | 아프탈리스 파르마 리미티드 | 장용 코팅된 저 강도 췌장 리파제 제제 |
| ES2558756T3 (es) | 2011-08-08 | 2016-02-08 | Aptalis Pharma Limited | Método para la prueba de disolución de composiciones sólidas que contienen enzimas digestivas |
| US10184121B2 (en) | 2013-06-28 | 2019-01-22 | Allergan Pharmaceuticals International Limited | Methods for removing viral contaminants from pancreatic extracts |
| RU2679832C2 (ru) | 2013-08-09 | 2019-02-13 | Аллерган Фармасьютикалз Интернэйшнл Лимитед | Композиция пищеварительных ферментов, подходящая для энтерального введения |
| CA2915671A1 (en) * | 2013-11-05 | 2015-05-14 | Allergan Pharmaceuticals International Limited | High potency pancreatin pharmaceutical compositions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3256150A (en) * | 1964-04-20 | 1966-06-14 | Dairyland Food Lab | Method for treating malabsorption syndrome |
| GB1139991A (en) * | 1965-07-19 | 1969-01-15 | Armour Pharma | Stabilized enzyme composition |
| FR6622M (de) * | 1967-09-12 | 1969-01-13 | ||
| JPS60501758A (ja) * | 1983-07-01 | 1985-10-17 | セルテク リミテツド | タンパク質、医薬構成物、遺伝子、ベクタ−宿主生物及びそれらの生産方法 |
| GB8421210D0 (en) * | 1984-08-21 | 1984-09-26 | Celltech Ltd | Polypeptide and polypeptide composition |
-
1986
- 1986-09-17 FR FR8612996A patent/FR2603804B1/fr not_active Expired
-
1987
- 1987-08-21 IS IS3251A patent/IS3251A7/is unknown
- 1987-08-25 ZA ZA876322A patent/ZA876322B/xx unknown
- 1987-08-26 NZ NZ221568A patent/NZ221568A/xx unknown
- 1987-09-04 DE DE87401984T patent/DE3784607T2/de not_active Expired - Fee Related
- 1987-09-04 EP EP87401984A patent/EP0261016B1/de not_active Expired - Lifetime
- 1987-09-04 AT AT87401984T patent/ATE86661T1/de not_active IP Right Cessation
- 1987-09-04 AU AU77956/87A patent/AU602349B2/en not_active Ceased
- 1987-09-04 ES ES87401984T patent/ES2053575T3/es not_active Expired - Lifetime
- 1987-09-08 IE IE240187A patent/IE59972B1/en not_active IP Right Cessation
- 1987-09-15 DK DK483087A patent/DK483087A/da not_active Application Discontinuation
- 1987-09-16 FI FI874038A patent/FI87232C/fi not_active IP Right Cessation
- 1987-09-16 NO NO873885A patent/NO170316C/no not_active IP Right Cessation
- 1987-09-16 CA CA000547006A patent/CA1308678C/en not_active Expired - Lifetime
- 1987-09-17 KR KR1019870010343A patent/KR960011522B1/ko not_active Expired - Fee Related
- 1987-09-17 US US07/097,896 patent/US5075231A/en not_active Expired - Lifetime
- 1987-09-17 JP JP62231219A patent/JPS6379589A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU7795687A (en) | 1988-03-24 |
| DK483087A (da) | 1988-03-18 |
| IE59972B1 (en) | 1994-05-04 |
| CA1308678C (en) | 1992-10-13 |
| EP0261016A1 (de) | 1988-03-23 |
| FI87232C (fi) | 1992-12-10 |
| FI874038L (fi) | 1988-03-18 |
| FI874038A0 (fi) | 1987-09-16 |
| DE3784607D1 (de) | 1993-04-15 |
| KR960011522B1 (ko) | 1996-08-23 |
| DE3784607T2 (de) | 1993-10-07 |
| AU602349B2 (en) | 1990-10-11 |
| ES2053575T3 (es) | 1994-08-01 |
| JPS6379589A (ja) | 1988-04-09 |
| IS3251A7 (is) | 1987-11-30 |
| KR880004084A (ko) | 1988-06-01 |
| DK483087D0 (da) | 1987-09-15 |
| NZ221568A (en) | 1991-11-26 |
| FR2603804A1 (fr) | 1988-03-18 |
| NO873885D0 (no) | 1987-09-16 |
| US5075231A (en) | 1991-12-24 |
| FI87232B (fi) | 1992-08-31 |
| ZA876322B (en) | 1988-03-02 |
| EP0261016B1 (de) | 1993-03-10 |
| FR2603804B1 (fr) | 1989-10-27 |
| IE872401L (en) | 1988-03-17 |
| NO170316C (no) | 1992-10-07 |
| NO170316B (no) | 1992-06-29 |
| NO873885L (no) | 1988-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |