ES2053575T3 - Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica. - Google Patents
Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica.Info
- Publication number
- ES2053575T3 ES2053575T3 ES87401984T ES87401984T ES2053575T3 ES 2053575 T3 ES2053575 T3 ES 2053575T3 ES 87401984 T ES87401984 T ES 87401984T ES 87401984 T ES87401984 T ES 87401984T ES 2053575 T3 ES2053575 T3 ES 2053575T3
- Authority
- ES
- Spain
- Prior art keywords
- lipasic
- lipases
- therapeutics
- extracts
- application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004882 Lipase Human genes 0.000 title abstract 2
- 108090001060 Lipase Proteins 0.000 title abstract 2
- 239000004367 Lipase Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 239000000284 extract Substances 0.000 title abstract 2
- 238000000926 separation method Methods 0.000 abstract 2
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000010828 elution Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 235000019421 lipase Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000002808 molecular sieve Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
Abstract
SE HACE SUBIR EN ESTOMAGOS DE CONEJOS O DE CABALLOS UNA EXTRACCION POR UN MEDIO ACUOSO ACIDO, SE AUMENTE EL EXTRACTO LIPASICO POR ADICION DE SALES HIDROSOLUBLES, DESPUES, POR UNA FILTRACION SOBRE TAMIZ MOLECULAR, SEGUIDAMENTE UNA SEPARACION POR CROMATOGRAFIA DE INTERCAMBIO IONICO, SE RECOGE UNA FRACCION DE ELUCION CONTENIENDO LA LIPASA. SE EMPLEA COMO MEDICAMENTO PARA LUCHAR CONTRA LAS MALAS ABSORCIONES GASTRICAS DE MATERIAS GRASAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8612996A FR2603804B1 (fr) | 1986-09-17 | 1986-09-17 | Lipases et extraits lipasiques, leur procede de preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2053575T3 true ES2053575T3 (es) | 1994-08-01 |
Family
ID=9339032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87401984T Expired - Lifetime ES2053575T3 (es) | 1986-09-17 | 1987-09-04 | Lipasas y extractos lipasicos, su procedimiento de preparacion y su aplicacion en terapeutica. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5075231A (es) |
| EP (1) | EP0261016B1 (es) |
| JP (1) | JPS6379589A (es) |
| KR (1) | KR960011522B1 (es) |
| AT (1) | ATE86661T1 (es) |
| AU (1) | AU602349B2 (es) |
| CA (1) | CA1308678C (es) |
| DE (1) | DE3784607T2 (es) |
| DK (1) | DK483087A (es) |
| ES (1) | ES2053575T3 (es) |
| FI (1) | FI87232C (es) |
| FR (1) | FR2603804B1 (es) |
| IE (1) | IE59972B1 (es) |
| IS (1) | IS3251A7 (es) |
| NO (1) | NO170316C (es) |
| NZ (1) | NZ221568A (es) |
| ZA (1) | ZA876322B (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2683549B1 (fr) * | 1991-11-13 | 1994-11-18 | Jouveinal Inst Rech | Acides nucleiques codant pour la lipase gastrique de lapin et derives polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques a base de ces derniers. |
| US5998189A (en) * | 1992-12-16 | 1999-12-07 | Warner-Lambert Company | Polypeptide derivatives of dog gastric lipase and pharmaceutical compositions containing same |
| FR2699179B1 (fr) * | 1992-12-16 | 1995-01-06 | Jouveinal Inst Rech | Acides nucléiques codant pour la lipase gastrique de chien et dérivés polypeptidiques, leur utilisation pour la production de ces polypeptides, et compositions pharmaceutiques à base de ces derniers. |
| FR2733249B1 (fr) * | 1995-04-20 | 1997-06-06 | Biocem | Lipase gastrique de chien recombinante et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations |
| JP2000026311A (ja) * | 1998-07-02 | 2000-01-25 | Amano Pharmaceut Co Ltd | 胃排出能亢進剤組成物 |
| US6770468B1 (en) | 1999-09-14 | 2004-08-03 | Genzyme Glycobiology Research Institute, Inc. | Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway |
| US6534300B1 (en) | 1999-09-14 | 2003-03-18 | Genzyme Glycobiology Research Institute, Inc. | Methods for producing highly phosphorylated lysosomal hydrolases |
| WO2001049282A2 (en) * | 2000-01-06 | 2001-07-12 | Martek Biosciences Corporation | Therapeutic preparations of highly unsaturated fatty acids |
| EP1149585A1 (en) * | 2000-04-27 | 2001-10-31 | Warner-Lambert Company | Use of recombinant gastric lipase for treating functional dyspepsia |
| US6800472B2 (en) | 2001-12-21 | 2004-10-05 | Genzyme Glycobiology Research Institute, Inc. | Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase |
| US6905856B2 (en) | 2001-12-21 | 2005-06-14 | Genzyme Glycobiology Research Institute, Inc. | Soluble GlcNAc phosphotransferase |
| DE102005010604B3 (de) * | 2005-03-06 | 2006-07-20 | Lange Uhren Gmbh | Uhr |
| KR100828146B1 (ko) * | 2006-04-28 | 2008-05-08 | 김우식 | 췌장 리파아제의 선택적 추출방법 |
| EP1870649A1 (en) | 2006-06-20 | 2007-12-26 | Octapharma AG | Lyophilisation targetting defined residual moisture by limited desorption energy levels |
| US8246950B2 (en) | 2007-02-20 | 2012-08-21 | Aptalis Pharma Limited | Stable digestive enzyme compositions |
| CA2702577A1 (en) | 2007-10-15 | 2009-04-23 | Jbs United, Inc. | Method for increasing performance of offspring |
| UA111726C2 (uk) | 2010-10-01 | 2016-06-10 | Апталіс Фарма Лімітед | Препарат панкреліпази низької сили з кишковорозчинним покриттям |
| CA2843556A1 (en) | 2011-08-08 | 2013-02-14 | Aptalis Pharma Ltd. | Method for dissolution testing of solid compositions containing digestive enzymes |
| MX2016001593A (es) | 2013-08-09 | 2016-09-29 | Allergan Pharmaceuticals Int Ltd | Composicion de enzima digestiva adecuada para administracion enterica. |
| MX2016000480A (es) * | 2013-11-05 | 2016-10-21 | Allergan Pharmaceuticals Int Ltd | Composiciones farmaceuticas de pancreatina de alta potencia. |
| JP2017519490A (ja) | 2014-06-19 | 2017-07-20 | アプタリス ファルマ リミテッド | 膵臓抽出物からのウイルス汚染の除去方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3256150A (en) * | 1964-04-20 | 1966-06-14 | Dairyland Food Lab | Method for treating malabsorption syndrome |
| GB1139991A (en) * | 1965-07-19 | 1969-01-15 | Armour Pharma | Stabilized enzyme composition |
| FR6622M (es) * | 1967-09-12 | 1969-01-13 | ||
| WO1985000381A1 (en) * | 1983-07-01 | 1985-01-31 | Celltech Limited | Proteins, pharmaceutical compositions, genes, vectors, host organisms and processes for their production |
| GB8421210D0 (en) * | 1984-08-21 | 1984-09-26 | Celltech Ltd | Polypeptide and polypeptide composition |
-
1986
- 1986-09-17 FR FR8612996A patent/FR2603804B1/fr not_active Expired
-
1987
- 1987-08-21 IS IS3251A patent/IS3251A7/is unknown
- 1987-08-25 ZA ZA876322A patent/ZA876322B/xx unknown
- 1987-08-26 NZ NZ221568A patent/NZ221568A/xx unknown
- 1987-09-04 ES ES87401984T patent/ES2053575T3/es not_active Expired - Lifetime
- 1987-09-04 AT AT87401984T patent/ATE86661T1/de not_active IP Right Cessation
- 1987-09-04 DE DE87401984T patent/DE3784607T2/de not_active Expired - Fee Related
- 1987-09-04 AU AU77956/87A patent/AU602349B2/en not_active Ceased
- 1987-09-04 EP EP87401984A patent/EP0261016B1/fr not_active Expired - Lifetime
- 1987-09-08 IE IE240187A patent/IE59972B1/en not_active IP Right Cessation
- 1987-09-15 DK DK483087A patent/DK483087A/da not_active Application Discontinuation
- 1987-09-16 FI FI874038A patent/FI87232C/fi not_active IP Right Cessation
- 1987-09-16 CA CA000547006A patent/CA1308678C/en not_active Expired - Lifetime
- 1987-09-16 NO NO873885A patent/NO170316C/no not_active IP Right Cessation
- 1987-09-17 JP JP62231219A patent/JPS6379589A/ja active Pending
- 1987-09-17 US US07/097,896 patent/US5075231A/en not_active Expired - Lifetime
- 1987-09-17 KR KR1019870010343A patent/KR960011522B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO873885D0 (no) | 1987-09-16 |
| DE3784607T2 (de) | 1993-10-07 |
| DE3784607D1 (de) | 1993-04-15 |
| JPS6379589A (ja) | 1988-04-09 |
| US5075231A (en) | 1991-12-24 |
| DK483087D0 (da) | 1987-09-15 |
| EP0261016A1 (fr) | 1988-03-23 |
| FR2603804B1 (fr) | 1989-10-27 |
| AU602349B2 (en) | 1990-10-11 |
| DK483087A (da) | 1988-03-18 |
| AU7795687A (en) | 1988-03-24 |
| FI87232C (fi) | 1992-12-10 |
| IS3251A7 (is) | 1987-11-30 |
| NZ221568A (en) | 1991-11-26 |
| FI87232B (fi) | 1992-08-31 |
| IE872401L (en) | 1988-03-17 |
| FI874038L (fi) | 1988-03-18 |
| FR2603804A1 (fr) | 1988-03-18 |
| CA1308678C (en) | 1992-10-13 |
| IE59972B1 (en) | 1994-05-04 |
| NO170316C (no) | 1992-10-07 |
| ATE86661T1 (de) | 1993-03-15 |
| NO170316B (no) | 1992-06-29 |
| NO873885L (no) | 1988-03-18 |
| FI874038A0 (fi) | 1987-09-16 |
| KR880004084A (ko) | 1988-06-01 |
| EP0261016B1 (fr) | 1993-03-10 |
| KR960011522B1 (ko) | 1996-08-23 |
| ZA876322B (en) | 1988-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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