ATE87213T1 - Potenzierung der erythropoiesis. - Google Patents

Potenzierung der erythropoiesis.

Info

Publication number: ATE87213T1
Authority: AT; Austria
Prior art keywords: erythropoiesis; inhibin; frp; modulating; potentation
Prior art date: 1987-11-13

Application number

AT88910384T

Other languages

English (en)

Inventor

John Chenc-Po Yu

Alice Lin-Tsing Yu

Joan Vaughan

Jean Edouard Frederic Rivier

Wylie Walker Vale Jr

Original Assignee

Salk Inst For Biological Studi

Scripps Clinic Res

Univ California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-13

Filing date

1988-11-14

Publication date

1993-04-15

1988-11-14 Application filed by Salk Inst For Biological Studi, Scripps Clinic Res, Univ California filed Critical Salk Inst For Biological Studi

1993-04-15 Application granted granted Critical

1993-04-15 Publication of ATE87213T1 publication Critical patent/ATE87213T1/de

Links

230000010437 erythropoiesis Effects 0.000 title abstract 4
239000000893 inhibin Substances 0.000 abstract 2
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 2
102000003951 Erythropoietin Human genes 0.000 abstract 1
108090000394 Erythropoietin Proteins 0.000 abstract 1
101000980898 Homo sapiens Cell division cycle-associated protein 4 Proteins 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000004069 differentiation Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229940105423 erythropoietin Drugs 0.000 abstract 1
210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
102000044493 human CDCA4 Human genes 0.000 abstract 1
OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
External Artificial Organs (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT88910384T 1987-11-13 1988-11-14 Potenzierung der erythropoiesis. ATE87213T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US07/120,470 US5032507A (en)	1987-11-13	1987-11-13	Potentiation of erythropoiesis
PCT/US1988/004063 WO1989004668A1 (en)	1987-11-13	1988-11-14	Potentiation of erythropoiesis
EP88910384A EP0346413B1 (de)	1987-11-13	1988-11-14	Potenzierung der erythropoiesis

Publications (1)

Publication Number	Publication Date
ATE87213T1 true ATE87213T1 (de)	1993-04-15

Family

ID=22390500

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88910384T ATE87213T1 (de)	1987-11-13	1988-11-14	Potenzierung der erythropoiesis.

Country Status (8)

Country	Link
US (1)	US5032507A (de)
EP (1)	EP0346413B1 (de)
JP (1)	JPH02502019A (de)
AT (1)	ATE87213T1 (de)
AU (1)	AU628309B2 (de)
CA (1)	CA1329762C (de)
DE (1)	DE3879685T2 (de)
WO (1)	WO1989004668A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196192A (en) *	1988-05-31	1993-03-23	Biotechnology Australia Pty. Ltd.	Actions of hormones
US4997815A (en) *	1988-11-01	1991-03-05	Children's Hospital Medical Center Of Northern California	Method for augmenting fetal hemoglobin by treatment with activin and/or inhibin
US5942220A (en) *	1990-03-16	1999-08-24	Chiron Corporation	Inhibitor of cytokine activity and applications thereof
US5061620A (en) *	1990-03-30	1991-10-29	Systemix, Inc.	Human hematopoietic stem cell
EP0548276A4 (en) *	1990-09-13	1993-12-29	Children's Hospital Medical Center Of Northern California	Method for increasing red blood cell production by treatment with activin or activin-related peptides
US5482924A (en) *	1991-05-06	1996-01-09	Centre National De La Recherche	Proteinaceous compositions having an activity on erythropoiesis
AU2677592A (en) *	1991-09-13	1993-04-27	New England Deaconess Hospital	Erythropoietin potentiating agents and methods for their use
US7910624B1 (en)	1995-03-03	2011-03-22	The Trustees Of Boston University	Compositions for the treatment of blood disorders
CA2141540A1 (en) *	1993-06-01	1994-12-08	Satomi Nishikawa	Monoclonal antibody, method for preparing the same and use of the same
US5487895A (en) *	1993-08-13	1996-01-30	Vitaphore Corporation	Method for forming controlled release polymeric substrate
AU7668894A (en) *	1993-08-13	1995-03-14	Vitaphore Corporation	Hydrogel-based microsphere drug delivery systems
WO1995011699A1 (en) *	1993-10-29	1995-05-04	The Trustees Of Boston University	Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
US5599705A (en) *	1993-11-16	1997-02-04	Cameron; Robert B.	In vitro method for producing differentiated universally compatible mature human blood cells
US6242417B1 (en)	1994-03-08	2001-06-05	Somatogen, Inc.	Stabilized compositions containing hemoglobin
US5631219A (en) *	1994-03-08	1997-05-20	Somatogen, Inc.	Method of stimulating hematopoiesis with hemoglobin
US6011000A (en) *	1995-03-03	2000-01-04	Perrine; Susan P.	Compositions for the treatment of blood disorders
US5728581A (en) *	1995-06-07	1998-03-17	Systemix, Inc.	Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
DE19612463C2 (de) *	1996-03-28	1998-04-30	Gsf Forschungszentrum Umwelt	Neues Protein mit differenzierungsinduzierender Aktivität für erythropoetische Zellen
WO1998004290A2 (en)	1996-07-26	1998-02-05	Perrine Susan P	Compositions comprising an inducing agent and an anti-viral agent for the treatment of blood, viral and cellular disorders
US5952226A (en) *	1996-11-05	1999-09-14	Modex Therapeutiques	Hypoxia responsive EPO producing cells
JP2002509077A (ja)	1998-02-09	2002-03-26	ユニヴァースティオブサザーンカリフォルニア	赤血球形成促進方法
AU774861B2 (en) *	1998-02-11	2004-07-08	Douglas V Faller	Compositions and methods for the treatment of cystic fibrosis
CA2521979A1 (en) *	2003-04-09	2004-10-28	University Of Utah Research Foundation	Compositions and methods related to production of erythropoietin
JP4819809B2 (ja) *	2004-07-28	2011-11-24	ユニベルシテ・ルネ・デカルト・パリ５	血管幹細胞及びその使用
WO2010105112A1 (en) *	2009-03-11	2010-09-16	Hemaquest Pharmaceuticals, Inc.	Detection of short-chain fatty acids in biological samples
US20110086869A1 (en)	2009-09-24	2011-04-14	The Trustees Of Boston University	Methods for treating viral disorders
WO2011072086A1 (en)	2009-12-08	2011-06-16	Hemaquest Pharmaceuticals, Inc.	Methods and low dose regimens for treating red blood cell disorders
US20110245154A1 (en)	2010-03-11	2011-10-06	Hemaquest Pharmaceuticals, Inc.	Methods and Compositions for Treating Viral or Virally-Induced Conditions
EP4650005A3 (de)	2016-07-15	2026-01-28	Viracta Subsidiary, Inc.	Histondeacetylasehemmer zur verwendung in der immuntherapie
CN114137194B (zh) *	2021-11-26	2023-09-29	南京中医药大学	一种基于补血效应的当归质量评价方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1341617C (en) *	1984-06-08	2011-06-28	Henry George Burger	Inhibin isolated from ovarian follicular fluid
JPH0637520B2 (ja) *	1985-07-03	1994-05-18	味の素株式会社	ポリペプチド
CA1302651C (en) *	1986-04-04	1992-06-02	Wylie Walker Vale, Jr.	Fsh-releasing peptide

1987
- 1987-11-13 US US07/120,470 patent/US5032507A/en not_active Expired - Lifetime
1988
- 1988-11-14 WO PCT/US1988/004063 patent/WO1989004668A1/en not_active Ceased
- 1988-11-14 EP EP88910384A patent/EP0346413B1/de not_active Expired - Lifetime
- 1988-11-14 CA CA000582960A patent/CA1329762C/en not_active Expired - Lifetime
- 1988-11-14 AU AU27140/88A patent/AU628309B2/en not_active Expired
- 1988-11-14 DE DE8888910384T patent/DE3879685T2/de not_active Expired - Lifetime
- 1988-11-14 JP JP63509583A patent/JPH02502019A/ja active Pending
- 1988-11-14 AT AT88910384T patent/ATE87213T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0346413A1 (de)	1989-12-20
WO1989004668A1 (en)	1989-06-01
EP0346413B1 (de)	1993-03-24
CA1329762C (en)	1994-05-24
DE3879685T2 (de)	1993-07-01
AU2714088A (en)	1989-06-14
DE3879685D1 (de)	1993-04-29
JPH02502019A (ja)	1990-07-05
AU628309B2 (en)	1992-09-17
US5032507A (en)	1991-07-16

Legal Events

Date	Code	Title	Description
1994-04-15	UEP	Publication of translation of european patent specification
2009-02-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE3879685D1 (de)	1993-04-29	Potenzierung der erythropoiesis.
ATE199096T1 (de)	2001-02-15	Il-11 aus säugetier
ATE253112T1 (de)	2003-11-15	Menschliche hematopoietische stammzellen
ES268633U (es)	1983-05-16	Estructura absorbente.
ES2147720T3 (es)	2000-10-01	Factor de celulas madre.
ES2053719T3 (es)	1994-08-01	Dimetilvermectinas no naturales y procedimiento para su preparacion.
IT7820120A0 (it)	1978-02-09	Proteine filate e processo per ottenere dette proteine.
IT7820821A0 (it)	1978-03-01	Procedimento per l'estinzione secca del coke e impianto per la sua realizzazione.
DE3789052D1 (de)	1994-03-24	Mittel zur Verbesserung der Haftung.
BR8007955A (pt)	1981-06-23	Catodos de hidrogenio com baixa sobretensao e processo de sua preparacao
BE855223R (fr)	1977-11-30	Phosphites organiques et leur utilisation comme stabilisants
ATE70453T1 (de)	1992-01-15	Verwendung von interleukin-1-proteinen gegen arthritis.
NL188249C (nl)	1992-05-06	Zuurstofmeetcel.
IT7921922A0 (it)	1979-04-17	Procedimento per la determinazione dell'attivita' della colinesterasi e derivati della colina che vengono impiegati nel procedimento.
DE3750344D1 (de)	1994-09-15	Beschleuniger der Aktivität von Hydrolase.
IT7825123A0 (it)	1978-06-29	Procedimento per produrre materiali per rotaie e , oppure per ruote, piu' stabili all'usura.
AU585279B2 (en)	1989-06-15	Pesticidal biphenylyloxy and biphenylylalkoxy aryl acyl urea compounds
GB1246436A (en)	1971-09-15	Improved game or teaching aid
IT1092166B (it)	1985-07-06	Fosforo rosso tabilizzato e procedimento per la sua produzione
BE848489A (fr)	1977-05-18	Halogenures d'acides sulfamiques et leur preparation,
ES8707706A1 (es)	1987-08-16	Un procedimiento para la preparacion de nuevos derivados de propanodiona.
GB871382A (en)	1961-06-28	Improvements in or relating to methods of manufacturing waveguide structures
JPS5390801A (en)	1978-08-10	Semiconductor laser switching system
SE8105057L (sv)	1982-03-11	Y-cirkulator enligt planledningsteknik
SU563367A1 (ru)	1977-06-30	Фильерный питатель