ATE87826T1 - Herstellung und verwendung von purpurinen, chlorinen und purpurin und chlorin enthaltenden zubereitungen. - Google Patents
Herstellung und verwendung von purpurinen, chlorinen und purpurin und chlorin enthaltenden zubereitungen.Info
- Publication number
- ATE87826T1 ATE87826T1 AT87900613T AT87900613T ATE87826T1 AT E87826 T1 ATE87826 T1 AT E87826T1 AT 87900613 T AT87900613 T AT 87900613T AT 87900613 T AT87900613 T AT 87900613T AT E87826 T1 ATE87826 T1 AT E87826T1
- Authority
- AT
- Austria
- Prior art keywords
- metal complexes
- purpurin
- chlorin
- purpurins
- chlorins
- Prior art date
Links
- BBNQQADTFFCFGB-UHFFFAOYSA-N purpurin Chemical compound C1=CC=C2C(=O)C3=C(O)C(O)=CC(O)=C3C(=O)C2=C1 BBNQQADTFFCFGB-UHFFFAOYSA-N 0.000 title abstract 6
- SURLGNKAQXKNSP-DBLYXWCISA-N chlorin Chemical compound C\1=C/2\N/C(=C\C3=N/C(=C\C=4NC(/C=C\5/C=CC/1=N/5)=CC=4)/C=C3)/CC\2 SURLGNKAQXKNSP-DBLYXWCISA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000002184 metal Substances 0.000 abstract 5
- 150000004035 chlorins Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81571486A | 1986-01-02 | 1986-01-02 | |
| US84212586A | 1986-03-18 | 1986-03-18 | |
| EP87900613A EP0256036B1 (de) | 1986-01-02 | 1986-12-31 | Herstellung und verwendung von purpurinen, chlorinen und purpurin und chlorin enthaltenden zubereitungen |
| PCT/US1986/002824 WO1987004071A1 (en) | 1986-01-02 | 1986-12-31 | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE87826T1 true ATE87826T1 (de) | 1993-04-15 |
Family
ID=27123989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87900613T ATE87826T1 (de) | 1986-01-02 | 1986-12-31 | Herstellung und verwendung von purpurinen, chlorinen und purpurin und chlorin enthaltenden zubereitungen. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0256036B1 (de) |
| AT (1) | ATE87826T1 (de) |
| CA (1) | CA1340951C (de) |
| DE (1) | DE3688253T2 (de) |
| WO (1) | WO1987004071A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216012A (en) * | 1986-01-02 | 1993-06-01 | University Of Toledo | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
| US5051415A (en) * | 1986-01-02 | 1991-09-24 | The University Of Toledo | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
| US5534506A (en) * | 1986-01-02 | 1996-07-09 | University Of Toledo | Use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
| US5109129A (en) * | 1989-09-29 | 1992-04-28 | The University Of Toledo, Medical College Of Ohio | Porphyrin derivatives |
| US5250668A (en) * | 1988-01-11 | 1993-10-05 | Morgan Alan R | Production and use of porphyrin derivatives and of compositions containing such derivatives |
| US4916711A (en) * | 1988-09-29 | 1990-04-10 | Boyer Joseph H | Lasing compositions and methods for using the same |
| US5446157A (en) * | 1990-04-23 | 1995-08-29 | Morgan; Lee R. | Boron difluoride compounds useful in photodynamic therapy and production of laser light |
| WO1995031197A1 (en) * | 1994-05-13 | 1995-11-23 | Monsanto Company | Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor |
| US6245758B1 (en) | 1994-05-13 | 2001-06-12 | Michael K. Stern | Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor |
| CN1090633C (zh) * | 1999-10-28 | 2002-09-11 | 许德余 | 叶绿素a降解产物金属络合物、其制备方法及抗胃溃疡药物 |
| US6605606B1 (en) * | 2000-08-04 | 2003-08-12 | Miravant Pharmaceuticals, Inc. | Solid forms of tin ethyl etiopurpurin and processes for producing such forms |
| RU2183956C1 (ru) * | 2001-03-30 | 2002-06-27 | Общество с ограниченной ответственностью "РАДА-ФАРМА" | Фотосенсибилизатор и способ его получения |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU581840B2 (en) * | 1982-09-27 | 1989-03-09 | Health Research Inc. | Porphyrin derivatives |
| DE142732T1 (de) * | 1983-10-24 | 1985-11-21 | Toyo Hakka Kogyo K.K., Okayama | Pheophorbidderivate und diese enthaltende pharmazeutische mittel. |
| JPS6092287A (ja) * | 1983-10-24 | 1985-05-23 | Toyo Hatsuka Kogyo Kk | 9−デスオキソ−9−ハイドロオキシ−フエオホ−バイド誘導体およびそれらのアルカリ塩類 |
-
1986
- 1986-12-31 AT AT87900613T patent/ATE87826T1/de not_active IP Right Cessation
- 1986-12-31 DE DE8787900613T patent/DE3688253T2/de not_active Expired - Lifetime
- 1986-12-31 EP EP87900613A patent/EP0256036B1/de not_active Expired - Lifetime
- 1986-12-31 CA CA000526575A patent/CA1340951C/en not_active Expired - Fee Related
- 1986-12-31 WO PCT/US1986/002824 patent/WO1987004071A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0256036B1 (de) | 1993-04-07 |
| EP0256036A4 (de) | 1989-11-30 |
| DE3688253D1 (de) | 1993-05-13 |
| EP0256036A1 (de) | 1988-02-24 |
| WO1987004071A1 (en) | 1987-07-16 |
| CA1340951C (en) | 2000-04-11 |
| DE3688253T2 (de) | 1993-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |